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| 1 | P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte- endothelial adhesion and promotes neurovascular injury during septic encephalopathy显示文摘 | Huan Wang Ling-Juan Hong Ji-Yun Huang Quan Jiang Rong-Rong Tao Chao Tan Nan-Nan Lu Cheng-Kun Wang Muhammad M Ahmed Ying-Mei Lu Zhi-Rong Liu Wei-Xing Shi En-Yin Lai Christopher S Wilcox Feng Han | 2015 | Cell Research2015，25，6： | 16 |
| 2 | Safety and success of precut biliary sphincterotomy: Is it linked to experience or expertise?显示文摘瞄准:决定成功的率和按规格裁切的复杂并发症胆汁的括约肌切开术(PBS ) 基于优先的经验并且到比较在 PBS 和标准内视镜的括约肌切开术(ES ) 之间的复杂并发症率。方法:回顾的评估有希望地在一个学术第三级的工作分派中心收集了非使随机化的数据。包括的学习没有 formal 在 PBS 训练的由单个 endoscopist 经历了 PBS 和 ES 的在一个八年的时期的所有病人。学习的主要结果措施是有到 ES 的复杂并发症的比较的 PBS 的成功和复杂并发症。结果:一个总数 2939 内视镜后退 cholangiopancreatographies (ERCP ) 在学习时期期间被执行,包括 818 (28%) ES 并且 150 (5%) PBS 过程。经由 PBS 的选择胆汁的管子在在 75% 病人的第一次尝试是成功的。管子被完成在一另外在一次随后的尝试(总数 87%) 的 13% 病人。从 PBS 的复杂并发症率比 ES 高是 45% ,但是没显著地不同[7%(10/50 ) 对 5%(38/818 ) , P = 0.29 ] 。任何一个从 PBS 的复杂并发症都不是严重的。向增加成功的一个重要趋势关于 endoscopist 存在 ?ˉs 在按规格裁切的第一次尝试(P = 0.0393,为趋势的 Cochran-Armitage 准确测试, Z =-1.7588) 。结论:尽管有在这种技术的特定的训练的缺乏, PBS 从另外的富有经验的中心与高成功率和类似于的复杂并发症率或不到报告被执行。这些结果建议内视镜的经验和也许天生的内视镜的技巧可以在这个过程的结果起一个重要作用。 | Lindsay S Robison Shyam Varadarajulu C Mel Wilcox | 2007 | World Journal of Gastroenterology2007，13，15： | 10 |
| 3 | On environmental threats to male infertility显示文摘 | Allen J Wilcox Jens Peter E Bonde | 2013 | Asian Journal of Andrology2013，15，2： | 7 |
| 4 | Sphincter of Oddi dysfunction Type Ⅲ: New studies suggest new approaches are needed显示文摘Sphincter of Oddi dysfunction(SOD) has been classified into three types based upon the presence or absence of objective findings including liver test abnormalities and bile duct dilatation. Type Ⅲ is the most controversial and is classified as biliary type pain in the absence ofany these objective findings. Many prior studies have shown that the clinical response to endoscopic therapy is higher based upon the presence of these objective criteria. However, there has been variable correlation of the manometry findings to outcome after endoscopic therapy. Nevertheless, manometry and sphincterotomy has been recommended for Type Ⅲ patients given the overall response rate of 33%, although the reported response rates are highly variable. However, all of the prior data was non-blinded and non-randomized with variable follow-up. The evaluating predictors in SOD study- a prospective randomized blinded sham controlled one year outcome study showed no correlation between manometric findings and outcome after sphincterotomy. Furthermore, patients receiving sham therapy had a statistically significantly better outcome than those undergoing biliary or dual sphincterotomy. This study calls into question the whole concept of SOD Type Ⅲ and, based upon prior physiologic studies, one can suggest that SOD Type Ⅲ likely represents a right upper quadrant functional abdominal pain syndrome and should be treated as such. | C Mel Wilcox | 2015 | World Journal of Gastroenterology2015，21，19： | 6 |
| 5 | Equal Efficacy of Endoscopic and Surgical Cystogastrostomy for Pancreatic Pseudocyst Drainage in a Randomized Trial显示文摘 | Shyam Varadarajulu Ji Young Bang Bryce S. Sutton Jessica M. Trevino John D. Christein C. Mel Wilcox | 2013 | Gastroenterology2013，，： | 6 |
| 6 | Endoscopic closure of a gastrocolic fistula using the over-the-scope-clip-system显示文摘Gastrointestinal (GI) defects such as fistulas and leaks can be potentially closed endoscopically using hemo-clips and loops. However, hemoclips may not allow for closure of large defects and they do not exert enough tensile force to keep fibrotic defects larger than 5 mm approximated. Herein we present a case of successful endoscopic closure of a gastrocolic fistula in a severely malnourished patient with complex post-surgical upper GI anatomy. We strongly believe that this device is a major breakthrough for the management of various types of discontinuity defects or fistulas. In addition, we show the usefulness of placing a direct jejunostomy using the double balloon enteroscopy (DBE) technique during the same procedure. The concept of providing direct jejunal feedings while allowing for upper gas-trointestinal bowel rest to promote the healing of the minimally invasive endoscopic operation is novel. Thus, our case is unique and exemplifies the utility of mini-mally invasive endoscopic endoluminal surgery. | Klaus Mnkemüller Shajan Peter Basem Alkurdi Jayapal Ramesh Daniel Popa C Mel Wilcox | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，8： | 5 |
| 7 | Use of anesthesia on the rise in gastrointestinal endoscopy显示文摘Conscious sedation has been the standard of care for many years for gastrointestinal endoscopic procedures. As procedures have become more complex and lengthy, additional medications became essential for adequate sedation. Often time's deep sedation is required for procedures such as endoscopic retrograde cholangiography which necessitates higher doses of narcotics and benzodiazepines or even use of other medications such as ketamine. Given its pharmacologic properties, pro-pofol was rapidly adopted worldwide to gastrointestinal endoscopy for complex procedures and more recently to routine upper and lower endoscopy. Many studies have shown superiority for both the physician and patient compared to standard sedation. Nevertheless, its use remains highly controversial. A number of studies worldwide show that propofol can be given safely by endoscopists or nurses when well trained. Despite this wealth of data, at many centers its use has been pro-hibited unless administered by anesthesiology. In this commentary, we review the use of anesthesia support for endoscopy in the United States based on recent data and its implications for gastroenterologists world-wide. | Basil Al-Awabdy C Mel Wilcox | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，1： | 5 |
| 8 | High-performance oxygen reduction and evolution carbon catalysis: From mechanistic studies to device integration显示文摘能容易集成于存在的高效、便宜的氧减小和进化催化剂的发展设备为利用 O 2-H2 O 化学,例如再生燃料房间和金属空气电池。此处,我们报导 NH 3-activated 做 N 的层次碳(NHC ) 催化剂经由一条可伸缩的线路综合了,并且表明它的设备集成。NHC 催化剂为氧减小反应(ORR ) 和氧进化反应(OER ) 展出了好性能,当综合时,借助于电气化学的研究和评估示威了进一个再生燃料房间的氧电极。为 ORR 和 OER 观察的活动比得上最先进的磅和红外催化剂在碱的环境完成的那些。我们进一步通过密度为电气化学的活动作为活跃地点识别了碳缺点的关键角色功能的理论计算和高分辨率的 TEM 可视化。这个工作加亮 NHC 的潜力在再生燃料房间并且可能代替商业宝贵金属为断断续续的可更新的精力的划算的存储的金属空气电池。 | John W. F. To Jia Wei Desmond Ng Samira Siahrostami Ai Leen Koh Yangjin Lee Zhihua Chen Kara D. Fong Shucheng Chen Jiajun He Won-Gyu Bae Jennifer Wilcox Hu Young Jeong Kwanpyo Kim Felix Studt Jens K. Nфrskov Thomas F. Jaramillo Zhenan Bao | 2017 | Nano Research2017，10，4： | 4 |
| 9 | Multipurpose use of the ‘bear claw’ (over‐the‐scope‐clip system) to treat endoluminal gastrointestinal disorders显示文摘 | Klaus M?nkemüller Shajan Peter Jay Toshniwal Daniel Popa Marzena Zabielski Richard D. Stahl Jayapal Ramesh C. Mel Wilcox | 2014 | Digestive Endoscopy2014，，3： | 4 |
| 10 | Post-processing of the full matrix of ultrasonic transmit–receive array data for non-destructive evaluation显示文摘 | Caroline Holmes Bruce W. Drinkwater Paul D. Wilcox | 2005 | NDT and E International2005，，8： | 2 |
| 11 | 慢性阻塞性肺疾病急性加重的标准化测量显示文摘背景和目的:COPD急性加重(AECOPD)反复发生是COPD病情进展的重要原因之一,减少AECOPD发生频率也是对COPD进行干预的主要目标之一。但是到目前为止,评估AECOPD的发生频率、严重程度和持续时间尚无有效的、标准化的监测工具。 | Leidy NK Wilcox TK Jones PW 白澎 孙永昌 | 2011 | 中华结核和呼吸杂志2011，34，9： | 2 |
| 12 | Vibro-modulation and Guided wave techniques for contact defect detection in plate显示文摘为在盘子中的接触缺点的察觉的一种非线性的声学的技术被开发把指导波浪与低频率颤动改变的vibro调整 techniques.The 联系在接触缺点以内的接口区域;然后,指导波浪从接触反映了的高频率的振幅和阶段背叛将是到退出接触缺点的 modulated.Due ,在调制指导波浪 series.Furthermore | JIAO Jingpin HE Cunfu WU Bin B. W. Drinkwater S. A. Neild P. D. Wilcox | 2011 | Chinese Journal of Acoustics2011，30，1： | 2 |
| 13 | EUS versus surgical cyst-gastrostomy for management of pancreatic pseudocysts显示文摘 | Shyam Varadarajulu Tercio L. Lopes C. Mel Wilcox Ernesto R. Drelichman Meredith L. Kilgore John D. Christein | 2008 | Gastrointestinal Endoscopy2008，，4： | 2 |
| 14 | Multiple transluminal gateway technique for EUS-guided drainage of symptomatic walled-off pancreatic necrosis显示文摘 | Shyam Varadarajulu Milind A. Phadnis John D. Christein C. Mel Wilcox | 2011 | Gastrointestinal Endoscopy2011，，1： | 2 |
| 15 | 体部肿瘤CT灌注方案:大鼠肿瘤模型的优化扫描参数显示文摘目的评估动物模型的CT检查中总扫描时间(TST)、扫描延迟间隔时间(ISD)、包括I衄管增强峰值图像(IPVE)以及输入功能血管的选择对计算肿瘤血流(BF)准确性的影响。方法所有动物研究方案和实验设计均经动物保护和应用委员会批准同意。注入0.2mL或0.4mL碘对比剂后.对6只患有乳腺癌的大鼠(每只有3个肿瘤)进行横断位扫描5min,扫描延迟间隔(ISD)1s(参考扫描),层厚2.5mm,间隔2.5mm,螺距1-3.120kV,240mA,旋转时间0.5s。根据不同的TST、ISD, | A. Tognolini R.S.Bardach O.S.Pianykh C.J. Wilcox V.Raptopoulos S.N. Goldberg 何珍(译) 万业达(校) | 2009 | 国际医学放射学杂志2009，32，4： | 2 |
| 16 | Strategies for antigen loading of dondritic cell to enhance the antitumor immune response显示文摘 | Strome S Voss S Wilcox R | 2002 | Cancer Res2002，62，： | 2 |
| 17 | Cinacalcet is efficacious in pediatric dialysis patients显示文摘 | Douglas M. Silverstein Kanwal K. Kher Asha Moudgil Mona Khurana Jennifer Wilcox Kathleen Moylan | 2008 | Pediatric Nephrology2008，，10： | 2 |
| 18 | Carbon dioxide conversion to valuable chemical products over composite catalytic systems显示文摘This paper reports an experimental study on catalytic conversion of carbon dioxide to methanol,ethanol and acetic acid.Catalysts having different catalytic functions were synthesized and combined in different ways to enhance the selectivity to desired products.The combined catalyst system possessed the following functions:methanol synthesis,Fischer-Tropsch synthesis,water-gas-shift and hydrogenation.Results showed that the methods of integrating these catalytic functions played an important role in achieving the desired product selectivity.We speculate that if methanol synthesis sites were located adjacent to the C-C chain growth sites,the formation rate of C_2 oxygenates would be enhanced.The advantage of using a high temperature methanol catalyst PdZnAl in the combined catalyst system was demonstrated.In the presence of PdZnAl catalyst,the combined catalyst system was stable at 380°C.It was observed that,at high temperature,kinetics favored oxygenate formation.The results implied that the process can be intensified by operating at high temperature using Pd-based methanol synthesis catalyst.Steam reforming of the byproduct organics was demonstrated as a means to provide supplemental hydrogen.Preliminary process design,simulation,and economic analysis of the proposed CO_2 conversion process were carried out.Economic analysis indicates how ethanol production cost was affected by the price of CO_2 and hydrogen. | Robert A.Dagle Jianli Hu Susanne B.Jones Wayne Wilcox John G.Frye James F.White Juyuan Jiang Yong Wang | 2013 | Journal of Energy Chemistry2013，22，3： | 2 |
| 19 | Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACNF2 and MTP 显示文摘 | Wilcox LJ Borradaile NM Dreu LE | 2001 | J Lipid Res2001，42，5： | 1 |
| 20 | Choiee oflong-term strategy for the management of patients with seveFe esophagitis: a cost utilityanalysis显示文摘 | Heudebert GR Marks R Wilcox CM | 1997 | Gastroenterolagy1997，112，4： | 1 |
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