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| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury显示文摘The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan,Hubei province,and rapidly spread to many provinces in China as well as other countries.Here we report the epidemiological,clinical,laboratory,and radiological characteristics,as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen,China.All 12 cases of the 2019-nCoV-infected patients developed pneumonia and half of them developed acute respiratory distress syndrome (ARDS).The most common laboratory abnormalities were hypoalbuminemia,lymphopenia,decreased percentage of lymphocytes (LYM) and neutrophils (NEU),elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH),and decreased CD8 count.The viral load of 2019-nCoV detected from patient respiratory tracts was positively linked to lung disease severity.ALB,LYM,LYM (%),LDH,NEU (%),and CRP were highly correlated to the acute lung injury.Age,viral load,lung injury score,and blood biochemistry indexes,albumin (ALB),CRP,LDH,LYM (%),LYM,and NEU (%),may be predictors of disease severity.Moreover,the Angiotensin Ⅱlevel in the plasma sample from 2019-nCoV infected patients was markedly elevated and linearly associated to viral load and lung injury.Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection. | Yingxia Liu Yang Yang Cong Zhang Fengming Huang Fuxiang Wang Jing Yuan Zhaoqin Wang Jinxiu Li Jianming Li Cheng Feng Zheng Zhang Lifei Wang Ling Peng Li Chen Yuhao Qin Dandan Zhao Shuguang Tan Lu Yin Jun Xu Congzhao Zhou Chengyu Jiang Lei Liu | 2020 | Science China(Life Sciences)2020，63，3： | 157 |
| 3 | Large-scale analysis of small RNAs derived from traditional Chinese herbs in human tissues显示文摘Plant-derived microRNAs have recently been reported to function in human blood and tissues. Controversy was immediately raised due to possible contamination and the lack of large sample sizes. Here, we report thousands of unique small RNAs derived from traditional Chinese medicine(TCM) herbs found in human blood cells and mouse lung tissues using a large-scale analysis.We extracted small RNAs from decoctions of 10 TCM plants(Ban Zhi Lian, Chai Hu, Chuan Xin Lian, Di Ding Zi Jin, Huang Qin, Jin Yin Hua, Lian Qiao, Pu Gong Ying, Xia Ku Cao, and Yu Xing Cao) and obtained millions of RNA sequences from each herb. We also obtained RNA-Seq data from the blood cells of humans who consumed herbal decoctions and from the lung tissues of mice administered RNAs from herbal decoctions via oral gavage. We identified thousands of unique small RNA sequences in human blood cells and mouse lung tissues. Some of these identified small RNAs from Chuan Xin Lian and Hong Jing Tian could be mapped to the genomes of the herbs, confirming their TCM plant origin. Small RNAs derived from herbs regulate mammalian gene expression in a sequence-specific manner, and thus are a superior novel class of herbal drug components that hold great potential as oral gene-targeted therapeutics, highlighting the important role of herbgenomics in their development. | Fengming Huang Jianchao Du Zhu Liang Zhichao Xu Jiantao Xu Yan Zhao Yexuan Lin Song Mei Quan He Jindong Zhu Qiang Liu Yanxu Zhang Yuhao Qin Wei Sun Jingyuan Song Shilin Chen Chengyu Jiang | 2019 | Science China(Life Sciences)2019，62，3： | 14 |
| 4 | The Coix Genome Provides Insights into Panicoideae Evolution and Papery Hull Domestication显示文摘Coix is a grass crop domesticated as early as the Neolithic era.It is still widely cultivated for both highly nutritional food and medicinal use.However,the genetic study and breeding of this crop are hindered by the lack of a sequenced genome.Here,we report de novo sequencing and assembly of the 1619-Mb genome of Coix,and annotation of 75.39%repeats and 39629 protein-coding genes.Comparative genomics analysis showed that Coix is more closely related to sorghum than maize,but intriguingly only Coix and maize had a recent genome duplication event,which was not detected in sorghum.We further constructed a genetic map and mapped several important traits,especially the strength of hull.Selection of papery hull(thin:easy dehulling)from the stony hull(thick:difficult dehulling)in wild progenitors was a key step in Coix domestication.The papery hull makes seed easier to process and germinate.Anatomic and global transcriptome analysis revealed that the papery hull is a result of inhibition of cell division and wall biogenesis.We also successfully demonstrated that seed hull pressure resistance is controlled by two major quantitative trait loci(QTLs),which are associated with hull thickness and color,respectively.The two QTLs were further fine mapped within intervals of 250 kb and 146 kb,respectively.These resources provide a platform for evolutionary studies and will facilitate molecular breeding of this important crop. | Chao Guo Yanan Wang Aiguo Yang Jun He Chaowen Xiao Shanhua Lv Fengming Han Yibing Yuan Yuan Yuan Xiaolong Dong Juan Guo YawenYang-Hailan Liu Ningzhi Zuo Yaxi Hu Kangxu Zhao Zhengbo Jiang Xing Wang Tingting Jiang Yaou Sherf Moju Cao Yuan Wang Zhaobo Long Tingzhao Rong Luqi Huang Shufeng Zhou | 2020 | Molecular Plant2020，13，2： | 11 |
| 5 | Application of Land-use Change Model in Guiding Regional Planning:A Case Study in Hun-Taizi River Watershed,Northeast China显示文摘This paper firstly investigated the land-use and land-cover change (LUCC) in the Hun-Taizi River watershed, Northeast China from 1988 to 2004 based on remotely sensed images and geographic information systems (GIS) technology. Then, using the famous land-use change model of Conversion of Land Use and its Effects at Small regional extent (CLUE-S), this paper simulated the land use changes under historical trend (HT), urban planning (UP) and ecological protection (EP) scenarios considering urban planning and ecological protection over the next 20 years. The simulated results under UP scenario in 2020 were compared with the planning map to assess the feasibility of using land-use change model to guide regional planning. Results show that forest land, dry farmland, paddy, and shrub land were the main land-use categories. Paddy and dry farmland being converted to urban area and rural settlement characterized the land-use change from 1988 to 2004. The main land-use categories changed over time. Landscape-pattern fragmentation will be worse under HT and UP scenarios, but better in EP scenario. The comparing results of simulated map with planning map in 2020 show that land-use change model is powerful tool to guide regional planning. Land-use scenarios can support regional planning and policy-making through analyzing future consequences scientifically. | LIU Miao HU Yuanman ZHANG Wei ZHU Junjun CHEN Hongwei XI Fengming | 2011 | Chinese Geographical Science2011，21，5： | 10 |
| 6 | Characteristics analysis of a novel centralized-driving flip-flow screen显示文摘During screening operation, blinding or clogging of screen perforations generally occurs to reduce the sieving capacity and efficiency. Recently, the flip-flow screening has been widely recognized as a feasible method to deal with the problem. In this paper, a novel centralized-driving flip-flow screen(CFS) was developed for the separation of fine and moist coal, and the key structures, namely, a centralized-driving mechanism and a quasi-circle beam mounted with the mat were designed for high reliability and stability. By means of a test on an experimental prototype, the effect of some factors, i.e., initial stretch and hardness of the polyurethane panel, respectively, and the rotation speed of the driving motor on the kinematic characteristic of the screen surface was investigated. Results show that without an initial stretch, the sieve mat generates the largest vibratory amplitude while the slacker the sieve mat initially is, the smaller amplitude it will accomplish. And an increase in the rotation speed could cause a rise in the vibratory amplitude. Unlike the two factors, the hardness does not have a definite effect on the kinematic performance, on which a further study is required. Finally, screening processing on a laboratory prototype was conducted to draw the conclusion that the developed CFS also has a high sieving efficiency for the fine and moist coal. | Peng Liping Li Fengming Dong Hailin Liu Chusheng Zhao Yuemin Duan Chenlong | 2014 | International Journal of Mining Science and Technology2014，24，2： | 9 |
| 7 | ACTIVE VIBRATION CONTROL OF FINITE L-SHAPED BEAM WITH TRAVELLING WAVE APPROACH显示文摘In this paper,the disturbance propagation and active vibration control of a finite L-shaped beam are studied.The dynamic response of the structure is obtained by the travelling wave approach.The active vibration suppression of the finite L-shaped beam is performed based on the structural vibration power flow.In the numerical calculation,the influences of the near field effect of the error sensor and the small error of the control forces on the control results are all considered.The simulation results indicate that the structural vibration response in the medium and high frequency regions can be effectively computed by the travelling wave method.The effect of the active control by controlling the power flow is much better than that by controlling the acceleration in some cases.And the control results by the power flow method are slightly affected by the locations of the error sensor and the small error of the control forces. | Chunchuan Liu Fengming Li1 Wenhu Huang(P.O.Box 137,School of Astronautics,Harbin Institute of Technology,Harbin 150001,China) | 2010 | Acta Mechanica Solida Sinica2010，23，5： | 8 |
| 8 | Elevated plasma levels of selective cytokines in COVID-19 patients reflect viral load and lung injury显示文摘A recent outbreak of pneumonia in Wuhan,China was found to be caused by a 2019 novel coronavirus(2019-nCoV or SARS-CoV-2 or HCoV-19).We previously reported the clinical features of 12 patients with2019-n Co V infections in Shenzhen,China.To further understand the pathogenesis of COVID-19 and find better ways to monitor and treat the disease caused by 2019-n Co V,we measured the levels of 48 cytokines in the blood plasma of those 12 COVID-19 patients.Thirty-eight out of the 48 measured cytokines in the plasma of 2019-n Co V-infected patients were significantly elevated compared to healthy individuals.Seventeen cytokines were linked to 2019-nCoV loads.Fifteen cytokines,namely M-CSF,IL-10,IFN-α2,IL-17,IL-4,IP-10,IL-7,IL-1 ra,G-CSF,IL-12,IFN-γ,IL-1α,IL-2,HGF and PDGF-BB,were strongly associated with the lung-injury Murray score and could be used to predict the disease severity of2019-n Co V infections by calculating the area under the curve of the receiver-operating characteristics.Our results suggest that 2019-nCoV infections trigger extensive changes in a wide array of cytokines,some of which could be potential biomarkers of disease severity of 2019-n Co V infections.These findings will likely improve our understanding of the immunopathologic mechanisms of this emerging disease.Our results also suggest that modulators of cytokine responses may play a therapeutic role in combating the disease once the functions of these elevated cytokines have been characterized. | Yingxia Liu Cong Zhang Fengming Huang Yang Yang Fuxiang Wang Jing Yuan Zheng Zhang Yuhao Qin Xiaoyun Li Dandan Zhao Shunwang Li Shuguang Tan Zhaoqin Wang Jinxiu Li Chenguang Shen Jianming Li Ling Peng Weibo Wu Mengli Cao Li Xing Zhixiang Xu Li Chen Congzhao Zhou William J Liu Lei Liu Chengyu Jiang | 2020 | National Science Review2020，7，6： | 6 |
| 9 | AntarcticaLC2000:The new Antarctic land cover database for the year 2000显示文摘Antarctica plays a key role in global energy balance and sea level change.It has been conventionally viewed as a whole ice body with high albedo in General Circulation Models or Regional Climate Models and the differences of land cover has usually been overlooked.Land cover in Antarctica is one of the most important drivers of changes in the Earth system.Detailed land cover information over the Antarctic region is necessary as spatial resolution improves in land process models.However,there is a lack of complete Antarctic land cover dataset derived from a consistent data source.To fill this data gap,we have produced a database named Antarctic Land Cover Database for the Year 2000(AntarcticaLC2000) using Landsat Enhanced Thematic Mapper Plus(ETM+) data acquired around 2000 and Moderate Resolution Imaging Spectrometer(MODIS) images acquired in the austral summer of 2003/2004 according to the criteria for the 1:100000-scale.Three land cover types were included in this map,separately,ice-free rocks,blue ice,and snow/firn.This classification legend was determined based on a review of the land cover systems in Antarctica(LCCSA) and an analysis of different land surface types and the potential of satellite data.Image classification was conducted through a combined usage of computer-aided and manual interpretation methods.A total of 4067 validation sample units were collected through visual interpretation in a stratified random sampling manner.An overall accuracy of 92.3%and the Kappa coefficient of 0.836 were achieved.Results show that the areas and percentages of ice-free rocks,blue ice,and snow/firn are 73268.81 km2(0.537%),225937.26 km2(1.656%),and 13345460.41 km2(97.807%),respectively.The comparisons with other different data proved a higher accuracy of our product and a more advantageous data quality.These indicate that AntarcticaLC2000,the new land cover dataset for Antarctica entirely derived from satellite data,is a reliable product for a broad spectrum of applications. | HUI FengMing KANG Jing LIU Yan CHENG Xiao GONG Peng WANG Fang LI Zhan YE YuFang GUO ZiQi | 2017 | Science China Earth Sciences2017，60，4： | 5 |
| 10 | Theories,technologies and practices of lacustrine shale oil exploration and development:A case study of Paleogene Kongdian Formation in Cangdong sag,Bohai Bay Basin,China显示文摘As the main factors affecting stable and high production and the production regularity of lacustrine shale oil are unclear,the theoretical understandings,key exploration and development technologies,development effect and production regularity of lacustrine shale oil have been analyzed and summarized based on 700 m cores taken systematically from Paleogene Kong 2 Member of 4 wells in Cangdong sag,over 100000 analysis data and formation testing data.Three theoretical understandings on shale oil enrichment and high production have been reached:(1)High-quality shale with“three highs and one low”is the material base for shale oil enrichment.(2)Medium-slightly high thermal evolution degree is the favorable condition for shale oil enrichment.(3)Laminar felsic shale is the optimal shale layer for oil enrichment in semi-deep lake facies.Key exploration and development technologies such as shale oil enrichment layer and area evaluation and prediction,horizontal well pattern layout,shale oil reservoir fracturing,optimization of shale oil production regime have been established to support high and stable shale oil production.Under the guidance of these theoretical understandings and technologies,shale oil in Cangdong sag has achieved high and stable production,and 4 of them had the highest production of over 100 tons a day during formation testing.In particular,Well GY5-1-1 L had a daily oil production of 208 m^(3).By April,2022,the 28 wells combined have a stable oil production of 300–350 tons a day,and have produced 17.8×10^(4) t of oil cumulatively.It is found that the shale oil production of horizontal well declines exponentially in natural flow stage,and declines in step pattern and then tends stable in the artificial lift stage.Proportion of light hydrocarbons in produced shale oil is in positive correlation with daily oil production and decreases regularly during production test. | ZHAO Xianzheng ZHOU Lihong PU Xiugang JIN Fengming HAN Wenzhong SHI Zhannan CHEN Changwei JIANG Wenya GUAN Quansheng XU Jing LIU Xuewei ZHANG Wei MA Jianying | 2022 | Petroleum Exploration and Development2022，49，3： | 4 |
| 11 | New bolting structure of fractured roof based on the Bossinesq equations显示文摘Present support theories contain a number of shortcomings in the designation of fractured roof bolt parameters of rectangular or trapezoidal coal roadways.Roof fall accidents occur easily in this kind of roadway.Based on the Bossinesq equations and the Mohr strength theory,we propose a theory of an anchored cluster structure for fractured roofs and have investigated the formation of such an anchored cluster structure,its self stability mechanism and mechanical properties.The results show that an anchor and the surrounding fractured rock can form a string-like supporting structure,referred to as the structure of an anchored cluster for rational bolt parameters.Not only can the structure maintain its own stability,but as well undertake the load of the overlying strata.The designated support parameters,based on anchored cluster theory can overcome the shortcomings of other support theories applied to a fractured roof of rectangular roadways or could not be calculated.Our anchored cluster theory can provide a theoretical basis for the design of support for rectangular fractured roofs.Furthermore,the theory will help to reduce the probability of roof fall accidents caused by local fractured rock blocks,which can destroy a supporting structure. | LIU, Hongtao MA, Nianjie ZHAO, Feihu LIU, Fengming | 2010 | Mining Science and Technology2010，20，2： | 4 |
| 12 | An improved Landsat Image Mosaic of Antarctica显示文摘A revised Landsat Image Mosaic of Antarctica (LIMA) is presented, using the 1073 multi-band scenes of the original Landsat-7 ETM+ LIMA image collection available at the United States Geological Survey (USGS: http://gffzza64998f73d704ee0hxwk60nb0owkw6b6b.ffgz.tsg.suse.edu.cn/). Three improvements have been applied during the data processing: (1) DN saturation is adjusted by adopting a linear regression, which has a lower root mean square error than the ratio regression used by LIMA; (2) solar elevation angle is calculated using pixel-level latitude/longitude and the acquisition time and date of the central pixel of the scene, improving slightly upon the bilinear interpolation of the solar elevation angles of scene corners applied in LIMA; and (3) two additional image bands, Band 5 and Band 7, are sharpened using the panchromatic band (Band 8) and a Gram-Schmidt Spectral Sharpening algorithm to more easily distinguish snow, cloud and exposed rocks. The final planetary reflectance product is stored in 16-bit bands to preserve the full radiometric content of the scenes. A comparative statistical analysis among 12 sample regions indicates that the new mosaic has enhanced visual qualities, information entropy, and information content for land cover classification relative to LIMA. | HUI FengMing CHENG Xiao LIU Yan ZHANG YanMei YE YuFang WANG XianWei LI Zhan WANG Kun ZHAN ZhiFei GUO JianHong HUANG HuaBing LI XiuHong GUO ZiQi GONG Peng | 2013 | Science China Earth Sciences2013，56，1： | 4 |
| 13 | Severe human infection with a novel avian-origin influenza A(H7N4) virus显示文摘Human infections with influenza H7 subtypes, such as H7N9, have raised concerns worldwide. Here, we report a human infection with a novel influenza A(H7N4) virus. A 68 years-old woman with cardiovascular and cholecystic comorbidities developed rapidly progressed pneumonia with influenza-like-illness as initial symptom, recovered after 23 days-hospitalization including 8 days in ICU. Laboratory indicators for liver and blood coagulation dysfunction were observed. Oseltamivir phosphate, glucocorticoids and antibiotics were jointly implemented, with nasal catheterization of oxygen inhalation for this patient.We obtained the medical records and collected serial respiratory and blood specimens from her. We collected throat, cloacal and/or feces samples of poultry and wild birds from the patient's backyard, neighborhood, local live poultry markets(LPMs) and the nearest lake. All close contacts of the patient were followed up and sampled with throat swabs and sera. Influenza viruses and other respiratory pathogens were tested by real-time RT-PCR, viral culturing and/or sequencing for human respiratory and bird samples. Micro-neutralizing assay was performed for sera. A novel reassortant wild bird-origin H7N4 virus is identified from the patient and her backyard poultry(chickens and ducks) by sequencing, which is distinct from previously-reported avian H7N4 and H7N9 viruses. At least four folds increase of neutralizing antibodies to H7N4 was detected in her convalescent sera. No samples from close contacts, wild birds or other poultry were tested positive for H7N4 by real-time RT-PCR. | Xiang Huo Lun-biao Cui Cong Chen Dayan Wang Xian Qi Ming-hao Zhou Xiling Guo Fengming Wang William J. Liu Weirong Kong Daxin Ni Ying Chi Yiyue Ge Haodi Huang Feifei Hu Chao Li Xiang Zhao Ruiqi Ren Chang-jun Bao George F. Gao Feng-Cai Zhu | 2018 | Science Bulletin2018，63，16： | 4 |
| 14 | Monitoring the Amery Ice Shelf front during 2004-2012 using ENVISAT ASAR data显示文摘The Amery Ice Shelf is the largest ice shelf in East Antarctica. It drains continental ice from an area of more than one million square kilometres through a section of coastline that represents approximately 2% of the total circumference of the Antarctic continent. In this study, we used a time series of ENVISAT ASAR images from 2004-2012 and flow lines derived from surface velocity data to monitor the changes in 12 tributaries of the Amery Ice Shelf front. The results show that the Amery Ice Shelf has been expanding and that the rates of expansion differ across the shelf. The highest average annual rate of advance from 2004-2012 was 3.36 m·d-1 and the lowest rate was 1.65 m·d-1 . The rates in 2009 and 2010 were generally lower than those in other years. There was a low correlation between the rate of expansion and the atmospheric temperature recorded at a nearby research station, however the mechanism of the relationship was complex. This study shows that the expansion of the Amery Ice Shelf is slowing down, reflecting a changing trend in climate and ice conditions in East Antarctica. | ZHAO Chen CHENG Xiao HUI Fengming KANG Jing LIU Yan WANG Xianwei WANG Fang CHENG Cheng FENG Zhunzhun CI Tianyu ZHAO Tiancheng ZHAI Mengxi | 2013 | Advances in Polar Science2013，24，2： | 4 |
| 15 | Detection of crevasses over polar ice shelves using Satellite Laser Altimeter显示文摘Ice shelf breakups account for most mass loss from the Antarctic Ice Sheet as the consequence of the propagation of crevasses(or rift)in response to stress.Thus there is a pressing need for detecting crevasses’location and depth,to understand the mechanism of calving processes.This paper presents a method of crevasse detection using the ICESat-1/GLAS data.A case study was taken at the Amery Ice Shelf of Antarctica to verify the accuracy of geo-location and depth of crevasses detected.Moreover,based on the limited crevasse points,we developed a method to detect the peak stress points which can be used to track the location of the crack tips and to identify the possible high-risk area where an ice shelf begins to break up.The spatial and temporal distribution of crevasse depth and the spatial distribution of peak stress points of the Amery Ice Shelf were analyzed through 132 tracks in 16 campaign periods of ICESat-1/GLAS between 2003 and 2008.The results showed that the depth of the detected crevasse points ranged from 2 to 31.7 m,which were above the sea level;the crevasse that advected downstream to the front edge of an ice shelf has little possibility to directly result in breakups because the crevasse depth did not show any increasing trend over time;the local stress concentration is distributed mainly in the suture zones on the ice shelves. | LIU Yan CHENG Xiao HUI FengMing WANG XianWei WANG Fang CHENG Cheng | 2014 | Science China Earth Sciences2014，57，6： | 3 |
| 16 | Functions and clinical significance of mechanical tumor microenvironment:cancer cell sensing,mechanobiology and metastasis显示文摘Dynamic and heterogeneous interaction between tumor cells and the surrounding microenvironment fuels the occurrence,progression,invasion,and metastasis of solid tumors.In this process,the tumormicroenvironment(TME)fractures cellular and matrix architecture normality through biochemical and mechanical means,abetting tumorigenesis and treatment resistance.Tumor cells sense and respond to the strength,direction,and duration of mechanical cues in the TME by various mechanotransduction pathways.However,far less understood is the comprehensive perspective of the functions and mechanisms of mechanotransduction.Due to the great therapeutic difficulties brought by the mechanical changes in the TME,emerging studies have focused on targeting the adverse mechanical factors in the TME to attenuate disease rather than conventionally targeting tumor cells themselves,which has been proven to be a potential therapeutic approach.In this review,we discussed the origins and roles ofmechanical factors in the TME,cell sensing,mechano-biological coupling and signal transduction,in vitro construction of the tumormechanicalmicroenvironment,applications and clinical significance in the TME. | Hanying Zhou Meng Wang Yixi Zhang Qingqing Su Zhengxin Xie Xiangyan Chen Ran Yan Ping Li Tingting Li Xiang Qin Hong Yang ChunhuiWu Fengming You Shun Li Yiyao Liu | 2022 | Cancer Communications2022，42，5： | 3 |
| 17 | Formation mechanism and height calculation of the caved zone and water-conducting fracture zone in solid backfill mining显示文摘To study the heights of the caved zone and water-conducting fracture zone in backfill mining,the failure mechanism of strata during backfill mining was analyzed,and a method for determining the heights of the two zones was proposed based on key strata theory.The movement and failure regularity of the strata above the backfilling panel were revealed through numerical simulation.Considering the geologic conditions of the CT101 backfilling panel,the height of the fracture zone was determined using the proposed method along with empirical calculation,numerical simulation,and borehole detection.The results of the new calculation method were similar to in situ measurements.The traditional empirical formula,which is based on the equivalent mining height model,resulted in large errors during calculation.The findings indicate the reliability of the new method and demonstrate its significance for creating reference data for related studies. | Lei Li Fengming Li Yong Zhang Daming Yang Xue Liu | 2020 | International Journal of Coal Science & Technology2020，7，1： | 3 |
| 18 | Band-gap Properties of Elastic Sandwich Metamaterial Plates with Composite Periodic Rod Core显示文摘A novel elastic sandwich metamaterial plate with composite periodic rod core is designed,and the frequency band-gap characteristics are numerically and experimentally investigated.The finite element and spectral element hybrid method(FE-SEHM)is developed to obtain the dynamic stiffness matrix of the sandwich metamaterial plate.The frequency response curves of the plate structure under the harmonic excitation are calculated using the presented numerical method and validated by the vibration experiment.By comparing with the frequency response curves of sandwich metamaterial plate with pure elastic rod core,improved band-gap properties are achieved from the designed metamaterial plate with composite periodic rod core.The elastic metamaterial plate with composite periodic rod core can generate more band-gaps,so it can suppress the vibration and elastic wave propagation in the structure more effectively. | Linzhongyang E Ziye Chen Fengming Liu Guangping Zou | 2022 | Acta Mechanica Solida Sinica2022，35，1： | 3 |
| 19 | A comprehensive analysis of the Bencao(herbal)small RNA Atlas reveals novel RNA therapeutics for treating human diseases显示文摘Cross-kingdom herbal mi RNA was first reported in 2012.Using a modified herbal extraction protocol,we obtained 73,677,287sequences by RNA-seq from 245 traditional Chinese Medicine(TCM),of which 20,758,257 were unique sequences.We constructed a Bencao(herbal)small RNA(s RNA)Atlas(http://gffzz4a3adbfa122d4a47hxwk60nb0owkw6b6b.ffgz.tsg.suse.edu.cn),annotated the sequences by sequence-based clustering,and created a nomenclature system for Bencao s RNAs.The profiles of 21,757 mi RNAs in the Atlas were highly consistent with those of plant mi RNAs in mi RBase.Using software tools,our results demonstrated that all human genes might be regulated by s RNAs from the Bencao s RNA Atlas,part of the predicted human target genes were experimentally validated,suggesting that Bencao s RNAs might be one of the main bioactive components of herbal medicines.We established roadmaps for oligonucleotide drugs development and optimization of TCM prescriptions.Moreover,the decoctosome,a lipo-nano particle consisting of 0.5%–2.5%of the decoction,demonstrated potent medical effects.We propose a Bencao(herbal)Index,including small-molecule compounds(SM),protein peptides(P),nucleic acid(N),non-nucleic and non-proteinogenic large-molecule compounds(LM)and elements from Mendeleev's periodic table(E),to quantitatively measure the medical effects of botanic medicine.The Bencao s RNA Atlas is a resource for developing gene-targeting oligonucleotide drugs and optimizing botanical medicine,and may provide potential remedies for the theory and practice of one medicine. | Yinghao Cao Yexuan Lin Na Sun Xinyi Du Yixin Dong Song Mei Xingyu Deng Xiaobei Li Shaoting Guo Kegong Tang Jiaqi Liu Xiangyu Qiao Dandan Zhao Yuhao Qin Cong Zhang Tianyi Xin Xiaohu Shi Congzhao Zhou Tao Dong De-an Guo Benedikt MKessler Dong Xu Jingyuan Song Fengming Huang Xiaoyue Wang Chengyu Jiang | 2023 | Science China(Life Sciences)2023，66，10： | 2 |
| 20 | ANALYSIS AND EXPERIMENT ON TRANSIENT DYNAMIC RESPONSE IN FINITE MINDLIN PLATE显示文摘The transient wave propagation in the finite rectangular Mindlin plate is investigated by the analytical and experimental methods. The generalized ray method (GRM) which has been successfully applied to study the transient responses of beams, planar trusses, space frames and infinite layered media is extended to investigate the transient wave propagation and early short time transient response in finite Mindlin plate. Combining the wave solution, the shock source and the boundary conditions, the ray groups transmitted in the finite rectangular plate can be determined. Numerical simulations and experiments are performed and compared with each other. The results show that the transient wave propagation and early short time transient responses in the finite plate can be studied using the GRM. The early short time transient accelerations are very large for the finite plate subjected to the unit impulse, while the early short time transient displacements are very small. The early short time transient accelerations under the unit impulse are much larger than those under the unit step impulse. The thickness and material characteristics have remarkable effects on the early short time transient responses. | Fengming Li Chunchuan Liu Tingwei Liang | 2013 | Acta Mechanica Solida Sinica2013，26，2： | 2 |
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