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| 1 | Four-sample lactose hydrogen breath test for diagnosis of lactose malabsorption in irritable bowel syndrome patients with diarrhea显示文摘AIM: To validate 4-sample lactose hydrogen breath testing(4SLHBT) compared to standard 13-sample LHBT in the clinical setting.METHODS: Irritable bowel syndrome patients with diarrhea(IBS-D) and healthy volunteers(HVs) were enrolled and received a 10 g, 20 g, or 40 g doselactose hydrogen breath test(LHBT) in a randomized, double-blinded, controlled trial. The lactase gene promoter region was sequenced. Breath samples and symptoms were acquired at baseline and every 15 min for 3 h(13 measurements). The detection rates of lactose malabsorption(LM) and lactose intolerance(LI) for a 4SLHBT that acquired four measurements at 0, 90, 120, and 180 min from the same data set were compared with the results of standard LHBT.RESULTS: Sixty IBS-D patients and 60 HVs were studied. The genotype in all participants was C/C-13910. LM and LI detection rates increased with lactose dose from 10 g, 20 g to 40 g in both groups(P < 0.001). 4SLHBT showed excellent diagnostic concordance with standard LHBT(97%-100%, Kappa 0.815-0.942) with high sensitivity(90%-100%) and specificity(100%) at all three lactose doses in both groups.CONCLUSION: Reducing the number of measurements from 13 to 4 samples did not significantly impact on the accuracy of LHBT in health and IBS-D. 4SLHBT is a valid test for assessment of LM and LI in clinical practice. | Jian-Feng Yang Mark Fox Hua Chu Xia Zheng Yan-Qin Long Daniel Pohl Michael Fried Ning Dai | 2015 | World Journal of Gastroenterology2015，21，24： | 4 |
| 2 | Tunable nonlinear refractive index of two-dimensional MoS2, WS2, and MoSe2 nanosheet dispersions [Invited]显示文摘Liquid-phase-exfoliation technology was utilized to prepare layered MoS2, WS2, and MoSe2 nanosheets in cyclohexylpyrrolidone. The nonlinear optical response of these nanosheets in dispersions was investigated by observing spatial self-phase modulation(SSPM) using a 488 nm continuous wave laser beam. The diffraction ring patterns of SSPM were found to be distorted along the vertical direction right after the laser traversing the nanosheet dispersions. The nonlinear refractive index of the three transition metal dichalcogenides dispersions n2 was measured to be 10-7cm2W-1, and the third-order nonlinear susceptibility χ(3)10-9 esu. The relative change of effective nonlinear refractive index Δn2e∕n(2e) of the MoS2, WS2, and MoSe2 dispersions can be modulated 0.012–0.240, 0.029–0.154, and 0.091–0.304, respectively, by changing the incident intensities. Our experimental results imply novel potential application of two-dimensional transition metal dichalcogenides in nonlinear phase modulation devices. | Gaozhong Wang Saifeng Zhang Xiaoyan Zhang Long Zhang Ya Cheng Daniel Fox Hongzhou Zhang Jonathan N.Coleman Werner J.Blau Jun Wang | 2015 | Photonics Research2015，3，2： | 4 |
| 3 | Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome显示文摘 | Jianfeng Yang Yanyong Deng Hua Chu Yanqun Cong Jianmin Zhao Daniel Pohl Benjamin Misselwitz Michael Fried Ning Dai Mark Fox | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 4 | DDX3X: stressing the NLRP3 inflammasome显示文摘Stress granules and inflammasomes are intracellular complexes that assemble in response to cellular stress signals,enabling cells to persist and perish,respectively.In a recent study published in Nature,Samir et al.identify the helicase DDX3X as a central decision maker in the formation of pro-survival stress granules or pro-death NLRP3 inflammasomes. | Daniel Fox Si Ming Man | 2019 | Cell Research2019，29，12： | 2 |
| 5 | Microscopic insight into the single step growth of in-plane heterostructures between graphene and hexagonal boron nitride显示文摘Graphene-h-BN hybrid nanostructures are grown in one step on the Pt(111) surface by ultra-high vacuum chemical vapor deposition using a single precursor,the dimethylamino borane complex.By varying the deposition conditions,different nanostructures ranging from a fully continuous hybrid monolayer to well-separated Janus nanodots can be obtained.The growth starts with heterogeneous nucleation on morphological defects such as Pt step edges and proceeds by the addition of small clusters formed by the decomposition of the dimethylamino borane complex.Scanning tunneling microscopy measurements indicate that a sharp zigzag in-plane boundary is formed when graphene grows aligned with the Pt substrate and consequently with the h-BN layer as well.When graphene is rotated by 30°,the graphene armchair edges are seamlessly connected to h-BN zigzag edges.This is confirmed by a thorough density functional theory (DFT) study.Angle resolved photoemission spectroscopy (ARPES) data suggests that both h-BN and graphene present the typical electronic structure of self-standing non-interacting materials. | Thanh Hai Nguyen Daniele Perilli Mattia Cattelan Hongsheng Liu Francesco Sedona Neil A. Fox Cristiana Di Valentin Stefano Agnoli | 2019 | Nano Research2019，12，3： | 2 |
| 6 | Data-Driven Discovery in Mineralogy: Recent Advances in Data Resources, Analysis, and Visualization显示文摘Large and growing data resources on the diversity, distribution, and properties of minerals are ushering in a new era of data-driven discovery in mineralogy. The most comprehensive international mineral database is the IMA database, which includes information on more than 5400 approved mineral species and their properties, and the mindat.org data source, which contains more than 1 million species/locality data on minerals found at more than 300 000 localities. Analysis and visualization of these data with diverse techniques—including chord diagrams, cluster diagrams, Klee diagrams, skyline diagrams, and varied methods of network analysis—are leading to a greater understanding of the co-evolving geosphere and biosphere. New data-driven approaches include mineral evolution, mineral ecology, and mineral network analysis—methods that collectively consider the distribution and diversity of minerals through space and time. These strategies are fostering a deeper understanding of mineral co-occurrences and, for the first time, facilitating predictions of mineral species that occur on Earth but have yet to be discovered and described. | Robert M. Hazen Robert T. Downs Ahmed Eleish Peter Fox Olivier C. Gagné Joshua J. Golden Edward S. Grew Daniel R. Hummer Grethe Hystad Sergey V. Krivovichev Congrui Li Chao Liu Xiaogang Ma Shaunna M. Morrison Feifei Pan Alexander J. Pires Anirudh Prabhu Jolyon Ralph Simone E. Runyon Hao Zhong | 2019 | Engineering2019，5，3： | 2 |
| 7 | Trends in Cardiovascular Disease Risk Factors in Individuals With and Without Diabetes Mellitus in the Framingham Heart Study显示文摘 | Sarah Rosner Preis Michael J. Pencina Shih-Jen Hwang Ralph B. D’Agostino Peter J. Savage Daniel Levy Caroline S. Fox | 2009 | Circulation2009，，3： | 1 |
| 8 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 9 | Investigation of coupled cobalt-silver nanoparticle system by plan view TEM | Daniel Fox Ruggero Verre Brendan J. O'Dowd Sunil K. Arora Colm C. Faulkner Igor V. Shvets | 2012 | Progress in Natural Science:Materials International2012，22，3： | 1 |
| 10 | A comparison of the index of complexity outcome and need (ICON)with the peer as- sessment rating (PAR)and the index of orthodontic treat- ment need (IOTN)显示文摘 | Fox NA Daniels C Gilgrass T | 2002 | Br Dent J2002，，4： | 1 |
| 11 | Cholinergic control mechanisms for im- munoreactive motilin release and motility in the canine duodenum 显示文摘 | Fox JET Daniel EE Jury J | 1983 | Can J Physiol Pharmacol1983，61，： | 1 |
| 12 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 13 | The use of measured boron concentration data from the GREAT-ER UK validation study(1996-1998) to generate predicted regional boron concentrations显示文摘 | FOX K K DANIEL M MORRIS G | 2000 | The Science of the Total Environment2000，，： | 1 |
| 14 | Activity and safety of crizotinib in patients with ALK -positive non-small-cell lung cancer: updated results from a phase 1 study显示文摘 | D Ross Camidge Yung-Jue Bang Eunice L Kwak A John Iafrate Marileila Varella-Garcia Stephen B Fox Gregory J Riely Benjamin Solomon Sai-Hong I Ou Dong-Wan Kim Ravi Salgia Panagiotis Fidias Jeffrey A Engelman Leena Gandhi Pasi A J?nne Daniel B Costa Geoffrey | 2012 | Lancet Oncology2012，，10： | 1 |
| 15 | Solution of population balance equations using the direct quadrature method of moments显示文摘 | Daniele L. Marchisio Rodney O. Fox | 2004 | Journal of Aerosol Science2004，，1： | 1 |
| 16 | Structural bases for function of circular muscle of canine corpus 显示文摘 | DANIEL E E SAKAI Y FOX JET | 1984 | Can J Physiol Pharmacol1984，62，： | 1 |
| 17 | Removal of linear alkylbenzene sulfonate from a small Yorkshire stream:contribution to GREAT-ER project # 7显示文摘 | Holt M Daniel M | 2000 | Science of the Total Environment2000，251，： | 1 |
| 18 | Outcomes After Cardioversion and Atrial Fibrillation Ablation in Patients Treated With Rivaroxaban and Warfarin in the ROCKET AF Trial显示文摘 | Jonathan P. Piccini Susanna R. Stevens Yuliya Lokhnygina Manesh R. Patel Jonathan L. Halperin Daniel E. Singer Graeme J. Hankey Werner Hacke Richard C. Becker Christopher C. Nessel Kenneth W. Mahaffey Keith A.A. Fox Robert M. Califf Günter Breithardt | 2013 | Journal of the American College of Cardiology2013，，19： | 1 |
| 19 | A novel and highly efficient synthetic route to unsymmetrical organoselenides using cesium base显示文摘 | Richard J Cohen Daniel L Fox Ralph Nicholas Salvatore | 2004 | J Org Chem2004，69，： | 1 |
| 20 | Pericardial Fat Is Associated With Prevalent Atrial Fibrillation: The Framingham Heart Study显示文摘 | George Thanassoulis Joseph M. Massaro Christopher J. O?Donnell Udo Hoffmann Daniel Levy Patrick T. Ellinor Thomas J. Wang Renate B. Schnabel Ramachandran S. Vasan Caroline S. Fox Emelia J. Benjamin | 2010 | Circulation: Arrhythmia and Electrophysiology2010，，4： | 1 |
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