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2269篇 您的检索式:作者名="Pohl"
    题名 作者 年代 出处 被引量
1Role of receptor tyrosine kinases in gastric cancer: New targets for a selective therapy显示文摘受体酷氨酸家族 ases (RTK ) 象表皮的生长因素受体家庭那样包括增长和变形传播参予肿瘤形成的几步。几已知的 RTK 起来在是主要的胃的癌症调整了定制的治疗的目标。仅仅初步的数据然而,在使用上存在当前临床上可得到的药象在胃的癌症的背景的 trastuzumab, cetuximab, bevacizumab, gefitinib, erlotinib,和 imatinib 那样。现出症状之前的潜的数据建议他们的使用的一个潜在的好处,特别在有“常规”的抑制细胞的联合治疗。这评论象新途径和药一样在癌症治疗关于他们的使用总结当前的知识优化治疗成功。JC Becker C Müller-Tidow H Serve W Domschke T Pohle 2006World Journal of Gastroenterology2006,12,21:19
2Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing显示文摘Helicobacter pylori(H.pylori)infection is highly prevalent in the human population and may lead to severe gastrointestinal pathology including gastric and duodenal ulcers,mucosa associated tissue lymphoma and gastric adenocarcinoma.In recent years,an alarming increase in antimicrobial resistance and subsequently failing empiric H.pylori eradication therapies have been noted worldwide,also in many European countries.Therefore,rapid and accurate determination of H.pylori’s antibiotic susceptibility prior to the administration of eradication regimens becomes ever more important.Traditionally,detection of H.pylori and its antimicrobial resistance is done by culture and phenotypic drug susceptibility testing that are cumbersome with a long turn-around-time.Recent advances in diagnostics provide new tools,like real-time polymerase chain reaction(PCR)and line probe assays,to diagnose H.pylori infection and antimicrobial resistance to certain antibiotics,directly from clinical specimens.Moreover,high-throughput whole genome sequencing technologies allow the rapid analysis of the pathogen’s genome,thereby allowing identification of resistance mutations and associated antibiotic resistance.In the first part of this review,we will give an overview on currently available diagnostic methods for detection of H.pylori and its drug resistance and their implementation in H.pylori management.The second part of the review focusses on the use of next generation sequencing technology in H.pylori research.To this end,we conducted a literature search for original research articles in English using the terms“Helicobacter”,“transcriptomic”,“transcriptome”,“next generation sequencing”and“whole genome sequencing”.This review is aimed to bridge the gap between current diagnostic practice(histology,rapid urease test,H.pylori culture,PCR and line probe assays)and new sequencing technologies and their potential implementation in diagnostic laboratory settings in order to complement the currently recommended H.pylori management guidelines and subsequently improve public health.Daniel Pohl Peter M Keller Valentine Bordier Karoline Wagner 2019World Journal of Gastroenterology2019,25,32:15
3The American Society for Gastrointestinal Endoscopy PIVI (Preservation and Incorporation of Valuable Endoscopic Innovations) on real-time endoscopic assessment of the histology of diminutive colorectal polyps显示文摘Douglas K. Rex Charles Kahi Michael O’Brien T.R. Levin Heiko Pohl Amit Rastogi Larry Burgart Tom Imperiale Uri Ladabaum Jonathan Cohen David A. Lieberman 2011Gastrointestinal Endoscopy2011,,3:7
4猪场的粪便管理系统显示文摘Steve Pohl 2003国外畜牧学(猪与禽)2003,,5:6
5臭气的控制显示文摘Steve Pohl 2004国外畜牧学(猪与禽)2004,,5:5
6Formation and migration of space charge packet in low density polyethylene显示文摘Pressure wave propagation (PWP) method was utilized to observe the space charges packet-like behavior in sheet samples of low-density polyethylene (LDPE) under the relative low electric field. The experimental results show that space charge packets are always generated at the anode and move across the sample to the cathode regard- less of the polarity of DC voltage. This paper discusses the migration of space charge packets at 30―40 ℃ , the possible charge resource of space charge packets carriers and trap level of the space charge.ZHENG Feihu 1 , ZHANG Yewen 1 , GONG Bin 1 , ZHU Jianwei 1 & WU Changshun 2 1. Pohl Institute of Solid State Physics, Tongji University, Shanghai 200092, China 2. China National Center for Quality Supervision and Test of Electric Ware and Cable, Shanghai 200093, China 2005Science China(Technological Sciences)2005,48,3:4
7Four-sample lactose hydrogen breath test for diagnosis of lactose malabsorption in irritable bowel syndrome patients with diarrhea显示文摘AIM: To validate 4-sample lactose hydrogen breath testing(4SLHBT) compared to standard 13-sample LHBT in the clinical setting.METHODS: Irritable bowel syndrome patients with diarrhea(IBS-D) and healthy volunteers(HVs) were enrolled and received a 10 g, 20 g, or 40 g doselactose hydrogen breath test(LHBT) in a randomized, double-blinded, controlled trial. The lactase gene promoter region was sequenced. Breath samples and symptoms were acquired at baseline and every 15 min for 3 h(13 measurements). The detection rates of lactose malabsorption(LM) and lactose intolerance(LI) for a 4SLHBT that acquired four measurements at 0, 90, 120, and 180 min from the same data set were compared with the results of standard LHBT.RESULTS: Sixty IBS-D patients and 60 HVs were studied. The genotype in all participants was C/C-13910. LM and LI detection rates increased with lactose dose from 10 g, 20 g to 40 g in both groups(P < 0.001). 4SLHBT showed excellent diagnostic concordance with standard LHBT(97%-100%, Kappa 0.815-0.942) with high sensitivity(90%-100%) and specificity(100%) at all three lactose doses in both groups.CONCLUSION: Reducing the number of measurements from 13 to 4 samples did not significantly impact on the accuracy of LHBT in health and IBS-D. 4SLHBT is a valid test for assessment of LM and LI in clinical practice.Jian-Feng Yang Mark Fox Hua Chu Xia Zheng Yan-Qin Long Daniel Pohl Michael Fried Ning Dai 2015World Journal of Gastroenterology2015,21,24:4
8Review article Multisensor image fusion in remote sensing: concepts, methods and applications显示文摘C. Pohl J. L. Van Genderen 1998International Journal of Remote Sensing1998,,5:3
9Single Cr atom catalytic growth of graphene显示文摘Huy Q. Ta Uang Zhao Wanjian Yin Darius Pohl Bemd Rellinghaus Thomas Gemming Barbara Trzebicka Justinas Palisaitis Gao Jing Per O. A. Persson Zhongfan Liu Alicja Bachmatiuk Mark H. Rummeli 2018Nano Research2018,11,5:3
10猪舍通风系统的设计显示文摘Steve Pohl 秦崇德 2005养殖技术顾问2005,,8:3
11Fibrin glue, healing of gastric mucosal injury, and expression of growth factors: results from a human in vivo study显示文摘Jan C. Becker Marion Beckbauer Wolfram Domschke Hermann Herbst Thorsten Pohle 2005Gastrointestinal Endoscopy2005,,4:2
12了解环境控制猪舍,获取最佳生产性能显示文摘Steve Pohl 2003国外畜牧学(猪与禽)2003,,5:2
13海水淡化(RO)应用风力发电的技术经济分析显示文摘现今风力发电能够提供低成本和长期稳定的能量,因而其竞争能力可与大型常规发电相伦比。在密集的工业领域应用风电仍然要求混合能源优化配比以平衡负荷端进行能量管理。介绍风能用于反渗透海水淡化作为一个完全集成的解决方案,并重点分析了风电在今后几年应用于中大型项目的能力和潜能。胡立伟 Joaxhim Kufler Robert Pohl Hadi Sader 2012珠江现代建设2012,,4:2
14深圳水围柠盟人才公寓显示文摘在深圳,城中村一直都是一个热门的话题,多种观点相互碰撞。在过去的一二十年里,城中村的改造就意味着大规模的拆迁,彻底推倒重建,拆迁改善了生活环境,创造了财富,但导致了城市空间匀质化,同时,造成了一些社会问题,更割断了城市的历史。目前深圳市新出台的政策是通过综合整治,让城中村全面进入柔性改造的通道,鼓励在原来的用地上开展城中村的综合整治。然而新政策出台不久之后,却又发生了原住民反对综合整治,要求城市更新的情况。说明政策的转变对城中村的居民和开发企业都产生了很大的影响,“综合整治”和“拆除重建”的投入产出模型完全不同,两种模式的转变,意味着居民的诉求和企业的战略都应当做出相应的调整,在新形势下共同努力,继续探索。为此,我们选登了通过综合整治获得比较成功的水围村项目,该项目保留了城市的肌理、文脉和集体记忆,同时,也提升了消防、市政配套,及改善了生活设施。并增加空中连廊、电梯,创造出了一个符合现代标准的宜居空间立体的社区。该项目改造后,由政府返租补贴,并以低于市场的价格出租,以确保改造后的房源租金在可负担的范围内。水围村项目为城中村的改造提供了一种可能,并引发了社会各界对城中村改造的再思考,这也反映出有关城中村的争论还在继续,城中村的改造还需要不断的探索……Chris Lai Jasmine M.Y.Tsoi Kwan Yee Wong Cindy Yan David Wen Demi Han Zachary Bao Jack Ou Nita Lin Red Liu Ann Hu Morning Dong Ananda de Vos Helene Pohl Arnound Stavenuiter Bert Oostdijk 王晓勇 2019世界建筑导报2019,34,1:2
15Thermoelectric properties of silicon and recycled silicon sawing waste显示文摘Large-scale-applicable thermoelectric materials should be both self-sustaining,in order to survive longterm duty cycles,and nonpolluting.Among all classes of known thermoelectric materials,these criteria reduce the available candidate pool,leaving silicon as one of the remaining options.Here we first review the thermoelectric properties of various silicon-related materials with respect to their morphologies and microstructures.We then report the thermoelectric properties of silicon sawing wastes recycled from silicon wafer manufacturing.We obtain a high power factor of~32 mWcm1 K2 at 1273 K with 6%phosphorus substitution in the Si crystal,a value comparable to that of phosphorus-doped silicongermanium alloys.Our work suggests the large-scale thermoelectric applicability of recycled silicon that would otherwise contribute to the millions of tons of industrial waste produced by the semiconductor industry.Ran He Wieland Heyn Felix Thiel Nicolas Perez Christine Damm Darius Pohl Bernd Rellinghaus Christian Reimann Maximilian Beier Jochen Friedrich Hangtian Zhu Zhifeng Ren Kornelius Nielsch Gabi Schierning 2019Journal of Materiomics2019,5,1:2
16Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome显示文摘Jianfeng Yang Yanyong Deng Hua Chu Yanqun Cong Jianmin Zhao Daniel Pohl Benjamin Misselwitz Michael Fried Ning Dai Mark Fox 2013Clinical Gastroenterology and Hepatology2013,,:2
17Water-aided colonoscopy: a systematic review显示文摘Felix W. Leung Arnaldo Amato Christian Ell Shai Friedland Judith O. Harker Yu-Hsi Hsieh Joseph W. Leung Surinder K. Mann Silvia Paggi Jürgen Pohl Franco Radaelli Francisco C. Ramirez Rodelei Siao-Salera Vittorio Terruzzi 2012Gastrointestinal Endoscopy2012,,3:2
18Incomplete Polyp Resection During Colonoscopy—Results of the Complete Adenoma Resection (CARE) Study显示文摘Heiko Pohl Amitabh Srivastava Steve P. Bensen Peter Anderson Richard I. Rothstein Stuart R. Gordon L. Campbell Levy Arifa Toor Todd A. Mackenzie Thomas Rosch Douglas J. Robertson 2013Gastroenterology2013,,:2
19Detection of Coronary Artery Stenoses With Thin-Slice Multi-Detector Row Spiral Computed Tomography and Multiplanar Reconstruction显示文摘Dieter Ropers Ulrich Baum Karsten Pohle Katharina Anders Stefan Ulzheimer Bernd Ohnesorge Christian Schlundt Werner Bautz Werner G. Daniel Stephan Achenbach 2003Circulation: Journal of the American Heart Association2003,,5:2
20Comparison of computed virtual chromoendoscopy and conventional chromoendoscopy with acetic acid for detection of neoplasia in Barrett’s esophagus显示文摘J. Pohl A. May T. Rabenstein O. Pech M. Nguyen-Tat A. Fissler-Eckhoff C. Ell 2007Endoscopy2007,,:2
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