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| 1 | Late biliary complications in human alveolar echinococcosis are associated with high mortality显示文摘AIM:To evaluate the incidence of late biliary complications in non-resectable alveolar echinococcosis(AE)under long-term chemotherapy with benzimidazoles.METHODS:Retrospective analysis of AE patients with biliary complications occurring more than three years after the diagnosis of AE.We compared characteristics of patients with and without biliary complications,analyzed potential risk factor for biliary complications and performed survival analyses.RESULTS:Ninety four of 148 patients with AE in Zurich had non-resectable AE requiring long-term benzimidazole chemotherapy,of which 26(28%)patients developed late biliary complications.These patients had a median age of 55.5(35.5-65)years at diagnosis of AE and developed biliary complications after 15(8.25-19)years of chemotherapy.The most common biliary complications during long-term chemotherapy were late-onset cholangitis(n=14),sclerosing cholangitis-like lesions(n=8),hepatolithiasis(n=5),affection of the common bile duct(n=7)and secondary biliary cirrhosis(n=7).Thirteen of the 26 patients had undergone surgery(including 12 resections)before chemotherapy.Previous surgery was a risk factor for late biliary complications in linear regression analysis(P=0.012).CONCLUSION:Late biliary complications can be observed in nearly one third of patients with non-resectable AE,with previous surgery being a potential risk factor.After the occurrence of late biliary complications,the median survival is only 3 years,suggesting that late biliary complications indicate a poor prognostic outcome. | Pascal Frei Benjamin Misselwitz Meher K Prakash Alain M Schoepfer Bettina M Prinz Vavricka Beat Müllhaupt Michael Fried Kuno Lehmann Rudolf W Ammann Stephan R Vavricka | 2014 | World Journal of Gastroenterology2014，20，19： | 5 |
| 2 | Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome显示文摘 | Jianfeng Yang Yanyong Deng Hua Chu Yanqun Cong Jianmin Zhao Daniel Pohl Benjamin Misselwitz Michael Fried Ning Dai Mark Fox | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 3 | Incidence and clinical relevance of heparin induced antibodies in patients with deep vein thrombosis treated with unfractionated or low- molecular weight heparin 显示文摘 | Lindhoff- Last E Nakov R Misselwitz F | 2002 | Br J Haematol2002，118，4： | 1 |
| 4 | Twin-totwin delivery time interval: influencing factors and effect on short-term outcome of the second twin 显示文摘 | Stein W Misselwitz B Schmidt S | 2008 | Acta Obstet Gynecol Scand2008，87，3： | 1 |
| 5 | Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial显示文摘 | Ajay K Kakkar Benjamin Brenner Ola E Dahl Bengt I Eriksson Patrick Mouret Jim Muntz Andrea G Soglian ákos F Pap Frank Misselwitz Sylvia Haas | 2008 | The Lancet2008，，9632： | 1 |
| 6 | Rates of bronchopulmo- nary dysplasia in very preterm neonates in Europe:results from the MOSAIC cohort显示文摘 | Gortner L Misselwitz B Milligan D | 2011 | Neonatology2011，99，2： | 1 |
| 7 | Politische Bildung in den neuen Lndern:In Verantwortung für die Demokratie in ganz Deutschland显示文摘 | Misselwitz H | 1992 | Politik und Zeitgeschichte1992，3738，： | 1 |
| 8 | MR Lymphography after Interstitial Injection of Contrast Media显示文摘 | Misselwitz B Platzek J Weinmann HJ | 1998 | Lymphology1998，31，2： | 1 |
| 9 | Rates of bronchopulmonary dysplasia in very preterm neonates in Europe:results from the MOSA显示文摘 | Gortner L Misselwitz B Milligan D | 2010 | Neonatology2010，99，2： | 1 |
| 10 | Gadofluorine 8: initial experience with a new contrast medium for interstitial MR lyrnphography显示文摘 | Misselwitz B Platzek J Raduchel B etal | 1999 | MAGMA1999，8，2： | 1 |
| 11 | Early MR Lymphography with Gadofluorine M in Rabbits显示文摘 | Misselwitz B Platzek J Weinmann H J | 2004 | Radiology2004，231，3： | 1 |
| 12 | Timecourse of health-related quality of life as determined 3,6 and 12 months after stroke:Relationship to neurological deficit,disability and depression显示文摘 | Suenkeler IH Nowak M Misselwitz B | 2002 | J Neurol2002，249，： | 1 |
| 13 | Predictors of in-hospital mortality and attributable risks of death after ischemic stroke:the Germam Stroke Registers Study Group显示文摘 | Heuschmann PU Kolominsky-Rabas PL Misselwitz B | 2004 | Arch Intern Med2004，164，16： | 1 |
| 14 | Interstitial MR lymphography using Gd-carrying lipsomes 显示文摘 | Misselwitz B Sachse A | 1997 | Acta Radiol Suppl1997，412，2： | 1 |
| 15 | Interstitial MR lymphography using Gd cartying liposomes显示文摘 | Misselwitz B Sachse A | 1997 | Acta Radio11997，412，38： | 1 |
| 16 | Matemal risks for newborn macrosomia,incidence of a shoulder dystocia and of damages of the plexus brachialis显示文摘 | Berle P Misselwitz B Scharlau J | 2003 | Z Geburtshilfe Neonatol2003，207，： | 1 |
| 17 | Do gender differences exist in pacemaker implantation---results of an obligatory external quality control program显示文摘 | Nowak B Misselwitz B Erdogan A | | 0，，02： | 1 |
| 18 | Dose-escalation study of rivaroxaban (BAY 59-7939) – an oral, direct Factor Xa inhibitor – for the prevention of venous thromboembolism in patients undergoing total hip replacement显示文摘 | Bengt I. Eriksson Lars C. Borris Ola E. Dahl Sylvia Haas Menno V. Huisman Ajay K. Kakkar Frank Misselwitz Eva Muehlhofer Peter K?lebo | 2007 | Thrombosis Research2007，，5： | 1 |
| 19 | Difference in Recognition of Right and Left Hemispheric Stroke显示文摘 | Foerch C Misselwitz B Sitzer M | 2005 | Lancet(S0140-6736)2005，366，9483： | 1 |
| 20 | Predictors of in-hospital mortality and attributable risks of death after ischemic stroke:the German Stroke Registers Study Group显示文摘 | Heuschmnann PU Kolominsky-Rabas PL Misselwitz B | 2004 | Arch Intern Med2004，164，10： | 1 |
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