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| 1 | 胃食管反流性疾病显示文摘胃食管反流性疾病(GORD)是一种常见病, 它可以导致多种症状,且与包括哮喘和食道腺癌在内的一些重要疾病有关遗传因素和生活方式比如吸烟,肥胖以及饮食行为都可能与GORD的发病有关胃食管相接处的结构和功能是反流性疾病发病的关键,此处的病变会导致一过性食道下端括约肌松弛,反流的风险及反流量增加如果没有报警症状,常规的内镜检查对于反流症状患者不是必需的质子泵抑制剂对大多数有典型反流症状的患者可以安全有效地长期缓解症状,但是对于不典型的症状效果较差非酸反流是导致病人对质子泵抑制剂治疗无效。 | Mark Fox Ian Forgacs 姚炜(译) 林三仁(校) | 2006 | 英国医学杂志中文版2006，9，2： | 8 |
| 2 | Four-sample lactose hydrogen breath test for diagnosis of lactose malabsorption in irritable bowel syndrome patients with diarrhea显示文摘AIM: To validate 4-sample lactose hydrogen breath testing(4SLHBT) compared to standard 13-sample LHBT in the clinical setting.METHODS: Irritable bowel syndrome patients with diarrhea(IBS-D) and healthy volunteers(HVs) were enrolled and received a 10 g, 20 g, or 40 g doselactose hydrogen breath test(LHBT) in a randomized, double-blinded, controlled trial. The lactase gene promoter region was sequenced. Breath samples and symptoms were acquired at baseline and every 15 min for 3 h(13 measurements). The detection rates of lactose malabsorption(LM) and lactose intolerance(LI) for a 4SLHBT that acquired four measurements at 0, 90, 120, and 180 min from the same data set were compared with the results of standard LHBT.RESULTS: Sixty IBS-D patients and 60 HVs were studied. The genotype in all participants was C/C-13910. LM and LI detection rates increased with lactose dose from 10 g, 20 g to 40 g in both groups(P < 0.001). 4SLHBT showed excellent diagnostic concordance with standard LHBT(97%-100%, Kappa 0.815-0.942) with high sensitivity(90%-100%) and specificity(100%) at all three lactose doses in both groups.CONCLUSION: Reducing the number of measurements from 13 to 4 samples did not significantly impact on the accuracy of LHBT in health and IBS-D. 4SLHBT is a valid test for assessment of LM and LI in clinical practice. | Jian-Feng Yang Mark Fox Hua Chu Xia Zheng Yan-Qin Long Daniel Pohl Michael Fried Ning Dai | 2015 | World Journal of Gastroenterology2015，21，24： | 4 |
| 3 | Prevalence and Presentation of Lactose Intolerance and Effects on Dairy Product Intake in Healthy Subjects and Patients With Irritable Bowel Syndrome显示文摘 | Jianfeng Yang Yanyong Deng Hua Chu Yanqun Cong Jianmin Zhao Daniel Pohl Benjamin Misselwitz Michael Fried Ning Dai Mark Fox | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 4 | Combining spatial modelling and radar to identify and protect avian migratory hot-spots显示文摘 | Mark DESHOLM Rashpal GILL Thomas BOVITH Anthony D. FOX | 2014 | Current Zoology2014，60，5： | 2 |
| 5 | The Effects of Dietary Fat and Calorie Density on Esophageal Acid Exposure and Reflux Symptoms显示文摘 | Mark Fox Carole Barr Suzanne Nolan Miranda Lomer Angela Anggiansah Terry Wong | 2007 | Clinical Gastroenterology and Hepatology2007，，4： | 2 |
| 6 | Agent-Oriented Supply-Chain Management显示文摘 | Mark S Fox MiHai Barbuceanu Rune Teigen | 2000 | The International Journal of Flexible Manufacturing System2000，，12： | 2 |
| 7 | DNA damage, poly (ADP-ribosyl) ation and apoptotic cell death as a potential common pathway of cytotoxic drug action显示文摘 | Marks D I Fox R M | 1991 | Biochemical pharmacology1991，42，10： | 1 |
| 8 | Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: A U.S.–Canadian multicenter study显示文摘 | Norbert Br?u Rena K. Fox Peiying Xiao Kristen Marks Zeenat Naqvi Lynn E. Taylor Anita Trikha Morris Sherman Mark S. Sulkowski Douglas T. Dieterich Michael O. Rigsby Teresa L. Wright Maria D. Hernandez Mamta K. Jain Gajendra K. Khatri Richard K. Sterling M | 2007 | Journal of Hepatology2007，，4： | 1 |
| 9 | Transoral Incisionless Fundoplication: 2-year Results from the Prospective Multicenter U.S. Study显示文摘 | Bell Reginald C W Barnes William E Carter Bart J Sewell Robert W Mavrelis Peter G Ihde Glenn M Hoddinott Kevin M Fox Mark A Freeman Katherine D Gunsberger Tanja Hausmann Mark G Dargis David Gill Brian DaCosta Wilson Erik Trad Karim S | 2014 | The American Surgeon2014，，11： | 1 |
| 10 | Evaluating implicit measures to improve web search显示文摘 | Steve Fox Kuldeep Karnawat Mark Mydland Susan Dumais Thomas White | 2005 | ACM Transactions on Information Systems (TOIS)2005，，2： | 1 |
| 11 | Agent-Oriented SupplyChain Management显示文摘 | Mihai Barbuceauu Rune Teigen | 2000 | The International Journal of Flexible Manufacturing Systems2000，12，： | 1 |
| 12 | E-commerce Business Models for the Musiclndustry 显示文摘 | Mark Fox | 2004 | Popular Music and Society2004，，27： | 1 |
| 13 | The inactivation of mussel catalase by oxygen显示文摘 | Marks G W Fox D L | 1993 | J Biol Chem1993，，103： | 1 |
| 14 | Characterization of CeO2-supported Cu-Pd bimetallic catalyst for the oxygen-assisted water-gas shift reaction显示文摘 | Fox Elise B Velu Subramani Engelhard Mark H | 2008 | Journal of Catalysis2008，260，： | 1 |
| 15 | Isoflurane inhibits the neurotransmitter release machinery显示文摘 | Herring B E Xie Z Marks J Fox A P | | 0，，02： | 1 |
| 16 | Ground Tests of Magnetometer-Based Autonomous Navigation (MAGNAV) for Low-Earth-Orbiting Spacecraft 显示文摘 | Mark L P Huang L Fox S M | 1993 | Journal of Guidance Control and Dynamics1993，16，1： | 1 |
| 17 | The relation between quantitative right ventricular ejection fraction and indices of tricuspid annular motion and myocardial performance显示文摘 | Darryl Miller Michel G Farah Anna Liner Keith Fox Mark Schluchter Brian D Hoit | 2004 | Journal of the American Society of Echocardiography2004，，5： | 1 |
| 18 | Male infertility,genetic analysis of the DAZ genes on the human Y chromosome and genetic analysis of DNA repair显示文摘 | Mark S Fox Renee A Reijo Pera | 2001 | Molecular and Cellular Endocrinology2001，184，： | 1 |
| 19 | Agent-Oriented Supply-Chain Management显示文摘 | Mark S. Fox Mihai Barbuceanu Rune Teigen | 2000 | International Journal of Flexible Manufacturing Systems (-)2000，，2： | 1 |
| 20 | The relation between quantitative right ventricular ejection fraction and indices of tricuspid annular motion and myocardial performance显示文摘 | Darryl Miller Michel G Farah Anna Liner Keith Fox Mark Schluchter Brian D Hoit | 2004 | Journal of the American Society of Echocardiography2004，，5： | 1 |
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