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| 1 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Julien Vergniol Juliette Foucher Brigitte Le Bail Elise Chanteloup Maud Haaser Monique Darriet Patrice Couzigou Victor de Lédinghen | 2005 | Gastroenterology2005,,2: | 8 |
| 2 | Pulsatile gonadotropin-releasing hormone therapy is associated with earlier spermatogenesis compared to combined gonadotropin therapy in patients with congenital hypogonadotropic hypogonadism显示文摘 | Jiang-Feng Mao Zhao-Xiang Liu Min Nie Xi Wang Hong-Li Xu Bing-Kun Huang Jun-Jie Zheng Le Min Ursula Brigitte Kaiser Xue-Yan Wu | 2017 | Asian Journal of Andrology2017,19,6: | 8 |
| 3 | Noninvasive assessment of liver fibrosis with impulse elastography: comparison of Supersonic Shear Imaging with ARFI and Fibroscan显示文摘 | Christophe Cassinotto Bruno Lapuyade Amaury Mouries Jean-baptiste Hiriart Julien Vergniol Delphine Gaye Claire Castain Brigitte Le Bail Faiza Chermak Juliette Foucher Fran?ois Laurent Michel Montaudon Victor De Ledinghen | 2014 | Journal of Hepatology2014,,: | 4 |
| 4 | Endocrine disrupting chemicals in mixture and obesity,diabetes and related metabolic disorders显示文摘Obesity and associated metabolic disorders represent a major societal challenge in health and quality of life with large psychological consequences in addition to physical disabilities. They are also one of the leading causes of morbidity and mortality. Although, different etiologic factors including excessive food intake and reduced physical activity have been well identified, they cannot explain the kinetics of epidemic evolution of obesity and diabetes with prevalence rates reaching pandemic proportions. Interestingly, convincing data have shown that environmental pollutants, specifically those endowed with endocrine disrupting activities, could contribute to the etiology of these multifactorial metabolic disorders. Within this review, we will recapitulate characteristics of endocrine disruption. We will demonstrate that metabolic disorders could originate from endocrine disruption with a particular focus on convincing data from the literature. Eventually, we will present how handling an original mouse model of chronic exposition to a mixture of pollutants allowed demonstrating that a mixture of pollutants each at doses beyond their active dose could induce substantial deleterious effects on several metabolic end-points. This proof-of-concept study, as well as other studies on mixtures of pollutants, stresses the needs for revisiting the current threshold model used in risk assessment which does not take into account potential effects of mixtures containing pollutants at environmental doses, e.g., the real life exposure. Certainly, more studies are necessary to better determine the nature of the chemicals to which humans are exposed and at which level, and their health impact. As well, research studies on substitute products are essential to identify harmless molecules. | Brigitte Le Magueresse-Battistoni Emmanuel Labaronne Hubert Vidal Danielle Naville | 2017 | World Journal of Biological Chemistry2017,8,2: | 4 |
| 5 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006,12,45: | 3 |
| 6 | Liver Fibrosis: Noninvasive Assessment with Acoustic Radiation Force Impulse Elastography—Comparison with FibroScan M and XL Probes and FibroTest in Patients with Chronic Liver Disease显示文摘 | Christophe Cassinotto Bruno Lapuyade Ania A?t-Ali Julien Vergniol Delphine Gaye Juliette Foucher Claire Bailacq-Auder Faiza Chermak Brigitte Le Bail Victor de Lédinghen | 2013 | Radiology2013,,1: | 3 |
| 7 | Controlled Attenuation parameter (CAP) for the diagnosis of steatosis: a prospective study of 5,323 examinations显示文摘 | Victor de Lédinghen Julien Vergniol Maylis Capdepont Faiza Chermak Jean-Baptiste Hiriart Christophe Cassinotto Wassil Merrouche Juliette Foucher Brigitte Le Bail | 2013 | Journal of Hepatology2013,,: | 3 |
| 8 | Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C显示文摘 | Julien Vergniol Juliette Foucher Eric Terrebonne Pierre–Henri Bernard Brigitte le Bail Wassil Merrouche Patrice Couzigou Victor de Ledinghen | 2011 | Gastroenterology2011,,7: | 3 |
| 9 | Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: Comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores显示文摘 | Laurent Castéra Brigitte Le Bail Fran?oise Roudot-Thoraval Pierre-Henri Bernard Juliette Foucher Wassil Merrouche Patrice Couzigou Victor de Lédinghen | 2008 | Journal of Hepatology2008,,1: | 1 |
| 10 | Imaging aspects and non-surgical interventional treatment in human alveolar echinococcosis显示文摘 | Solange Bresson-Hadni Eric Delabrousse Oleg Blagosklonov Brigitte Bartholomot Stéphane Koch Jean-Philippe Miguet Georges André Mantion Dominique Angèle Vuitton | 2005 | Parasitology International2005,,: | 1 |
| 11 | Liver Stiffness Measurement in Children Using FibroScan: Feasibility Study and Comparison With Fibrotest, Aspartate Transaminase to Platelets Ratio Index, and Liver Biopsy显示文摘 | Victor de Lédinghen Brigitte Le Bail Laurent Rebouissoux Céline Fournier Juliette Foucher Véronique Miette Laurent Castéra Laurent Sandrin Wassil Merrouche Frédéric Lavrand Thierry Lamireau | 2007 | Journal of Pediatric Gastroenterology and Nutrition2007,,4: | 1 |
| 12 | Outcome and Cost Analysis of Sacral Nerve Modulation for Treating Urinary and/or Fecal Incontinence显示文摘 | Anne-Marie Leroi Xavier Lenne Beno?t Dervaux Emmanuel Chartier-Kastler Brigitte Mauroy Lo?c Le Normand Philippe Grise Jean-Luc Faucheron Yann Parc Paul-Antoine Lehur Fran?ois Mion Henri Damon Xavier Barth Albert Leriche Christian Saussine Laurent Guy Fran | 2011 | Annals of Surgery2011,,4: | 1 |
| 13 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Julien Vergniol Juliette Foucher Brigitte Le Bail Elise Chanteloup Maud Haaser Monique Darriet Patrice Couzigou Victor de Lédinghen | 2005 | Gastroenterology2005,,2: | 1 |
| 14 | Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?显示文摘 | Kriz Wilhelm Kaissling Brigitte Hir Michel Le | 2011 | Journal of Clinical Investigation2011,,2: | 1 |
| 15 | Prognostic Factors and Longterm Survival after Hepatic Resection for Hepatocellular Carcinoma Originating from Noncirrhotic Liver显示文摘 | Christophe Laurent Jean Frédéric Blanc Steeve Nobili Antonio Sa Cunha Brigitte le Bail Paulette Bioulac-Sage Charles Balabaud Maylis Capdepont Jean Saric | 2005 | Journal of the American College of Surgeons2005,,5: | 1 |
| 16 | Characterization of renal interstitial fibroblast-specific protein?1/S100A4-positive cells in healthy and inflamed rodent kidneys显示文摘 | Michel Le Hir Ivan Hegyi Dominique Cueni-Loffing Johannes Loffing Brigitte Kaissling | 2005 | Histochemistry and Cell Biology (-)2005,,4: | 1 |
| 17 | Thalidomide for steroid-dependent immune reconstitution inflammatory syndromes during AIDS显示文摘 | Anne-Sophie Brunel Jacques Reynes Edouard Tuaillon Pierre-Alain Rubbo Olivier Lortholary Brigitte Montes Vincent Le Moing Alain Makinson | 2012 | AIDS2012,,16: | 1 |
| 18 | Expression of hepatocyte growth factor in human hepatocellular carcinoma显示文摘 | Josée Guirouilh Brigitte Le Bail Liliane Boussarie Charles Balabaud Paulette Bioulac-Sage Alexis Desmoulière Detlef Schuppan Jean Rosenbaum | 2001 | Journal of Hepatology2001,,1: | 1 |
| 19 | Diagnosis of liver fibrosis and cirrhosis using liver stiffness measurement: Comparison between M and XL probe of FibroScan?显示文摘 | Victor de Lédinghen Vincent Wai-Sun Wong Julien Vergniol Grace Lai-Hung Wong Juliette Foucher Shirley Ho-Ting Chu Brigitte Le Bail Paul Cheung-Lung Choi Faiza Chermak Karen Kar-Lum Yiu Wassil Merrouche Henry Lik-Yuen Chan | 2011 | Journal of Hepatology2011,,4: | 1 |
| 20 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Julien Vergniol Juliette Foucher Brigitte Le Bail Elise Chanteloup Maud Haaser Monique Darriet Patrice Couzigou Victor de Lédinghen | 2005 | Gastroenterology2005,,2: | 1 |