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| 1 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Julien Vergniol Juliette Foucher Brigitte Le Bail Elise Chanteloup Maud Haaser Monique Darriet Patrice Couzigou Victor de Lédinghen | 2005 | Gastroenterology2005，，2： | 8 |
| 2 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 3 | Prevalence and factors associated with failure of liver stiffness measurement using FibroScan in a prospective study of 2114 examinations显示文摘 | Juliette Foucher Laurent Castéra Pierre-Henri Bernard Xavier Adhoute David Laharie Julien Bertet Patrice Couzigou Victor de Lédinghen | 2006 | European Journal of Gastroenterology & Hepatology2006，，4： | 3 |
| 4 | Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C显示文摘 | Julien Vergniol Juliette Foucher Eric Terrebonne Pierre–Henri Bernard Brigitte le Bail Wassil Merrouche Patrice Couzigou Victor de Ledinghen | 2011 | Gastroenterology2011，，7： | 3 |
| 5 | Psychological impact of chronic hepatitis C:Comparison with other stressful life events and chronic diseases显示文摘瞄准:检验长期的丙肝(CHC ) 的心理影响在 CHC 病人的一个大队的诊断作为与带威胁生活的复杂并发症的风险的另外的紧张的生活事件和慢性病相比。方法:有补偿 CHC 的 185 个门诊病人被问到自我等级,用 100 公里 visual 类似物规模(管) ,应力的度由听说 CHC 诊断和他们的疾病的察觉的严厉引起了。诊断相关的应力与四个另外的紧张的生活事件相比并且察觉了严厉与四另外的普通慢性病相比的 CHC。结果:听说 CHC 诊断被认为一个主要紧张的事件(mean+/-SD 分数:72+/-25 ) ,显著地爱一个的不到死亡(89+/-13, P<0.0001 ) 并且离婚(78+/-23, P<0.007 ) ,但是多于工作打发(68+/-30, P<0.04 ) 并且家移动(26+/-24, P<0.0001 ) 。CHC 被认为严重疾病(74+/-19 ) ,在爱滋病以后(94+/-08, P<0.001 ) 并且癌症(91+/-11, P<0.001 ) ,但是在糖尿病前(66+/-23, P<0.001 ) 并且高血压(62+/-20, P<0.001 ) 。察觉的 CHC 严厉不与肝疾病的实际严厉有关,根据 Metavir 纤维变性 20 估计了。在里面多变量分析,诊断相关的应力与察觉的疾病严厉(P<0.001 ) 有关,特点焦虑(P<0.001 ) 和通过输血(P<0.001 ) 的感染。结论:我们的结果显示出 CHC 的诊断代表的可观的心理、感情的负担,甚至当重要的肝疾病不在时。当宣布 CHC 的诊断以便减少它的否定效果时,他们应该被考虑。 | Laurent Castera Aymery Constant Pierre-Henri Bernard Victor de Ledinghen Patrice Couzigou | 2006 | World Journal of Gastroenterology2006，12，10： | 2 |
| 6 | Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: Comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scores显示文摘 | Laurent Castéra Brigitte Le Bail Fran?oise Roudot-Thoraval Pierre-Henri Bernard Juliette Foucher Wassil Merrouche Patrice Couzigou Victor de Lédinghen | 2008 | Journal of Hepatology2008，，1： | 1 |
| 7 | Primary transcripts of microRNAs encode regulatory pep- tides显示文摘 | LAURESSERGUES D COUZIGOU JM CLEMENTE HS | 2015 | Nature2015，520，7545： | 1 |
| 8 | Short pe ripheral venous catheters:effect of evidence-based guide lines on insertion,maintenance and outcomes in auniver sity hospital显示文摘 | Couzigou C Lamory J Salmon-Ceron D | 2006 | J Hosp Infect2006，59，1： | 1 |
| 9 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Julien Vergniol Juliette Foucher Brigitte Le Bail Elise Chanteloup Maud Haaser Monique Darriet Patrice Couzigou Victor de Lédinghen | 2005 | Gastroenterology2005，，2： | 1 |
| 10 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Julien Vergniol Juliette Foucher Brigitte Le Bail Elise Chanteloup Maud Haaser Monique Darriet Patrice Couzigou Victor de Lédinghen | 2005 | Gastroenterology2005，，2： | 1 |
| 11 | Detection of nodules in liver cirrhosis: spiral computed tomography or magnetic resonance imaging? A prospective study of 88 nodules in 34 patients显示文摘 | Victor de Lédinghen David Laharie Robin Lecesne Brigitte Le Bail Maria Winnock Pierre-Henri Bernard Jean Saric Patrice Couzigou Charles Balabaud Paulette Bioulac-Sage Jacques Drouillard | 2002 | European Journal of Gastroenterology & Hepatology2002，，2： | 1 |
| 12 | Prospective comparison of two algorithms combining non-invasive methods for staging liver fibrosis in chronic hepatitis C显示文摘 | Laurent Castéra Giada Sebastiani Brigitte Le Bail Victor de Lédinghen Patrice Couzigou Alfredo Alberti | 2009 | Journal of Hepatology2009，，2： | 1 |
| 13 | Pitfalls of liver stiffness measurement: A 5‐year prospective study of 13,369 examinations显示文摘 | Laurent Castéra Juliette Foucher Pierre‐Henri Bernard Fran?oise Carvalho Daniele Allaix Wassil Merrouche Patrice Couzigou Victor de Lédinghen | 2010 | Hepatology2010，，3： | 1 |
| 14 | Alcohol and aldehyde dehydrogenase genetypes alcoholism and alcohol related disease显示文摘 | Couzigou P Coutelle C Fleury B | 1994 | Alcohol Alcohol Supple1994，2，： | 1 |
| 15 | Noninvasive Tests for Fibrosis and Liver Stiffness Predict 5-Year Outcomes of Patients With Chronic Hepatitis C显示文摘 | Julien Vergniol Juliette Foucher Eric Terrebonne Pierre–Henri Bernard Brigitte le Bail Wassil Merrouche Patrice Couzigou Victor de Ledinghen | 2011 | Gastroenterology2011，，7： | 1 |
| 16 | Detection of HCV-RNA in saliva of patients with chronic hepatitis C显示文摘 | Couzigou P Richard L Dumas F | | 0，，： | 1 |
| 17 | 显示文摘 | Couzigou P | 2013 | Presse Med2013，42，12： | 1 |
| 18 | Interferon-gamma with peginterferon alpha-2a and ribavirin in nonresponder pa- tients with chronic hepatitis C (ANRS HC16 GAMMATRI) 显示文摘 | Couzigou P Perusat S Bourliere M | 2013 | J Gastroenterol Hepatol2013，28，2： | 1 |
| 19 | Alcohol and aldehyde dehydrogenase genetypes alcoholism and alcohol related disease 显示文摘 | Couzigou P Coutelle C Fleury B | 1994 | Alcohol Alcohol Supple1994，2，： | 1 |
| 20 | Hepatitis B virus genotypes : a retrospective survey in Southwestern France, 1999-2004显示文摘 | Pascale Trimoulet Mathieu Boutonnet Maria Winnock Muriel Faure Marc-Arthur Loko Victor De Lédinghen Pierre-Henri Bernard Laurent Castéra Juliette Foucher Michel Dupon Jean-Marie Ragnaud Marie-édith Lafon Patrice Couzigou Fran?ois Dabis Hervé Fleury Didier | 2007 | Gastroenterologie Clinique et Biologique2007，，12： | 1 |
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