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| 1 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 2 | Controlled Attenuation parameter (CAP) for the diagnosis of steatosis: a prospective study of 5,323 examinations显示文摘 | Victor de Lédinghen Julien Vergniol Maylis Capdepont Faiza Chermak Jean-Baptiste Hiriart Christophe Cassinotto Wassil Merrouche Juliette Foucher Brigitte Le Bail | 2013 | Journal of Hepatology2013，，： | 3 |
| 3 | Impact of Tumor Response on Survival After Radiochemotherapy in Locally Advanced Rectal Carcinoma显示文摘 | Anne Rullier Christophe Laurent Maylis Capdepont Véronique Vendrely Paulette Bioulac-Sage Eric Rullier | 2010 | The American Journal of Surgical Pathology2010，，4： | 1 |
| 4 | Risk factors for fecal incontinence after intersphincteric resection for rectal cancer显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 5 | Prognostic Factors and Longterm Survival after Hepatic Resection for Hepatocellular Carcinoma Originating from Noncirrhotic Liver显示文摘 | Christophe Laurent Jean Frédéric Blanc Steeve Nobili Antonio Sa Cunha Brigitte le Bail Paulette Bioulac-Sage Charles Balabaud Maylis Capdepont Jean Saric | 2005 | Journal of the American College of Surgeons2005，，5： | 1 |
| 6 | Risk factors for fecal incontinence after intersphincteric resection for rectal cancer显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，： | 1 |
| 7 | Lymph nodes after preoperative ehemoradiotherapy for rectal carcinoma:number, status, and impact on survival 显示文摘 | Rullier A Laurent C Capdepont M | 2008 | Am J Surg Pathol2008，32，1： | 1 |
| 8 | Risk factors for fecal in- continence after intersphincteric resection for rectal cancer显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 9 | Risk factors for fecal incontinence after intersphincteric resection for rectal cancer 显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 10 | Lymph nodes after preoperative chemoradiotherapy for rectal carcinoma: number, status, and impact on survival显示文摘 | Rullier A Laurent C Capdepont M | 2008 | Am J Surg Pathol2008，32，1： | 1 |
| 11 | Impact of mucosal healing on long‐term outcomes in ulcerative colitis treated with infliximab: a multicenter experience显示文摘 | D. Laharie J. Filippi X. Roblin S. Nancey J.‐B. Chevaux X. Hébuterne B. Flourié M. Capdepont L. Peyrin‐Biroulet | 2013 | Aliment Pharmacol Ther2013，，10： | 1 |
| 12 | Risk factors for fecal incontinence after intersphincteric resection for rectal cancer显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 13 | Risk factorsfor fecal incontinence after intersphincteric resectionfor rectal cancer显示文摘 | Denost Q Laurent M Capdepont F | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 14 | Risk factors for fecal incontinence after interspbincteric resection for rectal cancer显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 15 | Risk factors for fecal in- continence after intersphincteric resection for rectal cancer显示文摘 | Denost Q Laurent C Capdepont M et aI | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 16 | Risk factors for fe-cal incontinence after intersphincteric resection for rectalcancer显示文摘 | Denost Q Laurent C Capdepont M | 2011 | Dis Colon Rectum2011，54，8： | 1 |
| 17 | Controlled at- tenuation parameter (CAP) for the diagnosis of steatosis: a pro- spective study of 5323 examinations显示文摘 | de Ledinghen V Vergniol J Capdepont M | 2014 | J Hepatol2014，60，5： | 1 |
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