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| 1 | Relationship between the severity of hepatitis C virus-related liver disease and the presence of Helicobacter species in the liver: A prospective study显示文摘AIM: To determine the presence of Helicobacter species DNA in the liver of chronic hepatitis C (CHC) patients with and without cirrhosis as compared to controls, and to identify the bacterial species involved. METHODS: Seventy-nine consecutive patients (HBV and HIV negative) with a liver sample obtained after liver biopsy or hepatic resection were studied: 41 with CHC without cirrhosis, 12 with CHC and cirrhosis, and 26 controls (HCV negative). Polymerase chain reactions (PCRs) targeting Helicobacter 16S rDNA and species- specific were performed on DNA extracted from the liver. A gastric infection with H pylori was determined by serology and confirmed by 13C-urea breath test. RESULTS: Overall, Helicobacter 16S rDNA was found in 16 patients (20.2%). Although positive cases tended to be higher in CHC patients with cirrhosis (41.6%) than in those without cirrhosis (17.0%) or in controls (15.4%), the difference was not statistically significant (P =0.08). H pylori-like DNA was identified in 12 cases and H. pullorum DNA in 2, while 2 cases remained unidenti- fied. Gastric infection with H pylori was found in only 2 of these patients. CONCLUSION: Our results do not confirm the associ- ation of Helicobacter species DNA in the liver of CHC patients with advanced liver disease. The lack of correlation between positive H pylori serology and the presence of H pylori-like DNA in the liver may indicate the presence of a variant of this species. | Laurent Castéra Anne Pedeboscq Marcia Rocha Brigitte Le Bail Corinne Asencio Victor de Lédinghen Pierre-Henri Bernard Christophe Laurent Marie-Edith Lafon Maylis Capdepont Patrice Couzigou Paulette Bioulac-Sage Charles Balabaud FrancisMégraud Armelle Ménard | 2006 | World Journal of Gastroenterology2006，12，45： | 3 |
| 2 | Controlled Attenuation parameter (CAP) for the diagnosis of steatosis: a prospective study of 5,323 examinations显示文摘 | Victor de Lédinghen Julien Vergniol Maylis Capdepont Faiza Chermak Jean-Baptiste Hiriart Christophe Cassinotto Wassil Merrouche Juliette Foucher Brigitte Le Bail | 2013 | Journal of Hepatology2013，，： | 3 |
| 3 | SK channels in excita- bility,pacemaking and synaptic integration显示文摘 | Bond CT Maylie J Adelman JP | 2005 | Curr Opin Neurobiol2005，15，3： | 1 |
| 4 | Impact of Tumor Response on Survival After Radiochemotherapy in Locally Advanced Rectal Carcinoma显示文摘 | Anne Rullier Christophe Laurent Maylis Capdepont Véronique Vendrely Paulette Bioulac-Sage Eric Rullier | 2010 | The American Journal of Surgical Pathology2010，，4： | 1 |
| 5 | Small-conductance Ca2 + - activated K + channels: form and function显示文摘 | Adelman JP Maylie J Sah P | 2012 | Annu Rev Physiol2012，74，： | 1 |
| 6 | SK channels in excitability, pacemaking and synaptic integration显示文摘 | BOND C T MAYLIE J ADELMAN J P | 2005 | Curr Opin Neurobiol2005，15，3： | 1 |
| 7 | SK channels in excitability, paeemaking and synaptie integration显示文摘 | Bond CT Maylie J Adelman JP | 2005 | Current Opinion in Neurobiology2005，15，： | 1 |
| 8 | Small- conductance Ca2 +- activated K ~ channe type 2 (SK2) modulates hJppocampal learning, memory, and synaptic plasticity显示文摘 | Hammond RS Bond CT Strassmaier T Ngo-Anh T J Adelman JP Maylie J | 2006 | J Neurosci2006，26，6： | 1 |
| 9 | Prognostic Factors and Longterm Survival after Hepatic Resection for Hepatocellular Carcinoma Originating from Noncirrhotic Liver显示文摘 | Christophe Laurent Jean Frédéric Blanc Steeve Nobili Antonio Sa Cunha Brigitte le Bail Paulette Bioulac-Sage Charles Balabaud Maylis Capdepont Jean Saric | 2005 | Journal of the American College of Surgeons2005，，5： | 1 |
| 10 | Coupet & Thierry Mayer, Institutional Determinants of Foreign Direct Investment 显示文摘 | Benassy Quere Agnes Maylis | 2007 | The World Economy2007，30，： | 1 |
| 11 | Institutional Determinants of Foreign Direct Investment显示文摘 | Agnès Bénassy-Quéré Maylis Coupet and Thierry Mayer | 2007 | The World Economy2007，，01022： | 1 |
| 12 | Small conductance Ca^2+ -activated K^+ channels and calmodulin显示文摘 | Maylie J Bond CT Herson PS | 2004 | J Physiol2004，554，2： | 1 |
| 13 | Gating of recombinant small-conductance Ca-activated K^+ channels by calcium显示文摘 | Hirschberg B Maylie J Adelman JP | 1998 | J Gen Physiol1998，111，： | 1 |
| 14 | Small-conductance calcium-acti-vated potassium channels 显示文摘 | Maylie J Adelman JP | 1999 | Ann NY Acad Sci1999，868，： | 1 |
| 15 | Small-conductance Ca2 + -activated K + channels : form and function 显示文摘 | Adelman JP Maylie J Sah P | 2012 | Annu Rev Physiol2012，74，12： | 1 |
| 16 | Stimulation dependent faciliation of the high threshold calcium current in guinea-pig ventricular myocytes显示文摘 | Maylie J | 1990 | J Physiol(Lond)1990，428，： | 1 |
| 17 | Smal-conductance,calcium-activated potassium channels from mammalian brain显示文摘 | K?hler M Hirschberg B Bond CT Kinzie JM Marrion NV Maylie J | 1996 | Science1996，273，5282： | 1 |
| 18 | Determinants of Apamin and d-tubocurarine block in SKpotassium channels显示文摘 | Ishii TM Maylie J Adelman JP | 1997 | J Biol Chem1997，272，23： | 1 |
| 19 | Organization and regulation of small conductance Caz+ -activated K+channels multip- rotein complexes显示文摘 | Allen D Fakler B Maylie J | 2007 | Neurosci2007，27，9： | 1 |
| 20 | SK channels in excita- bility, pacemaking and synaptic integration显示文摘 | Bond CT Maylie J Adelman JP | 2005 | Curr Opin Neurobiol2005，15，3： | 1 |
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