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| 1 | Evaluation of intrahepatic manifestation and distant extrahepatic disease in alveolar echinococcosis显示文摘BACKGROUND The main endemic areas of alveolar echinococcosis(AE)are in Central Europe and Western China.Both the infiltration of intrahepatic vascular and bile duct structures as well as extrahepatic disease can lead to further complications and may increase morbidity in patients with AE.AIM To evaluate vascular/biliary involvement in hepatic AE and its distant extrahepatic disease manifestations in an international collective was the aim.METHODS Consecutively,five experienced examiners evaluated contrast-enhanced abdominal computed tomography(CT)scans for 200 patients with hepatic AE of each of four locations(n=50)in Germany,France and China.Therefore,we retrospectively included the 50 most recent abdominal contrast-enhanced CT examinations at each center,performed because of hepatic AE from September 21,2007 to March 21,2018.AE liver lesions were classified according to the echinococcosis multilocularis Ulm classification for CT(EMUC-CT).Distant extrahepatic manifestations were documented either by whole body positron emission tomography–CT or with the addition of thoracic CT and cranial magnetic resonance imaging.Vascular/biliary involvement of the hepatic disease as well as the presence of distant extrahepatic manifestations were correlated with the EMUC-CT types of liver lesion.Statistical analysis was performed using SAS Version 9.4(SAS Institute Inc.,Cary,NC,United States).RESULTS Distant extrahepatic AE manifestations were significantly more frequent in China than in Europe(P=0.0091).A significant relationship was found between the presence of distant extrahepatic disease and AE liver lesion size(P=0.0075).Vascular/biliary structures were involved by the liver lesions significantly more frequently in China than in Europe(P<0.0001),and vascular/biliary involvement depended on lesion size.Different morphological types of AE liver lesions led to varying frequencies of vascular/biliary involvement and were associated with different frequencies of distant extrahepatic manifestations:Vascular/biliary involvement as a function of lesions primary morphology ranged from 5.88%of type IV liver lesions to 100%among type III lesions.Type IV differed significantly in these associations from types I,II,and III(P<0.0001).With respect to extrahepatic disease,the primary morphology types IV and V of liver lesions were not associated with any case of distant extrahepatic disease.In contrast,distant extrahepatic manifestations in types I–III were found to varying degrees,with a maximum of 22%for type III.CONCLUSION Different CT morphological patterns of hepatic AE lesions influence vascular/biliary involvement and the occurrence of distant extrahepatic manifestations.There are intercontinental differences regarding the characteristics of AE manifestation. | Tilmann Graeter Hai-Hua Bao Rong Shi Wen-Ya Liu Wei-Xia Li Yi Jiang Julian Schmidberger Eleonore Brumpt Eric Delabrousse Wolfgang Kratzer | 2020 | World Journal of Gastroenterology2020，26，29： | 7 |
| 2 | Clinical characteristics and outcomes of patients with hepatic angiomyolipoma:A literature review显示文摘First reported in 1976,hepatic angiomyolipoma(HAML)is a rare mesenchymal liver tumor occurring mostly in middle-aged women.Diagnosis of the liver mass is often incidental on abdominal imaging due to the frequent absence of specific symptoms.Nearly 10%of HAMLs are associated with tuberous sclerosis complex.HAML contains variable proportions of blood vessels,smooth muscle cells and adipose tissue,which renders radiological diagnosis hazardous.Cells express positivity for HMB-45 and actin,thus these tumors are integrated into the group of perivascular epithelioid cell tumors.Typically,a HAML appears on magnetic resonance imaging(or computed tomography scan)as a hypervascular solid tumor with fatty areas and with washout,and can easily be misdiagnosed as other liver tumors,particularly hepatocellular carcinoma.The therapeutic strategy is not clearly defined,but surgical resection is indicated for symptomatic patients,for tumors showing an aggressive pattern(i.e.,changes in size on imaging or high proliferation activity and atypical epithelioid pattern on liver biopsy),for large(>5 cm)biopsy-proven HAML,and if doubts remain on imaging or histology.Conservative management may be justified in other conditions,since most cases follow a benign clinical course.In summary,the correct diagnosis of HAML is challenging on imaging and relies mainly on pathological findings. | Paul Calame Gaelle Tyrode Delphine Weil Verhoeven Sophie Felix Anne Julia Klompenhouwer Vincent Di Martino Eric Delabrousse Thierry Thevenot | 2021 | World Journal of Gastroenterology2021，27，19： | 5 |
| 3 | WHO classification of alveolar echinococcosis: Principles and application显示文摘 | Peter Kern Hao Wen Naoki Sato Dominique A. Vuitton Beate Gruener Yinmei Shao Eric Delabrousse Wolfgang Kratzer Solange Bresson-Hadni | 2005 | Parasitology International2005，，： | 2 |
| 4 | Gallstone ileus:CT findings显示文摘 | Delabrousse E Bartholomot B Sohm O | 2000 | Eur Radiol2000，10，6： | 1 |
| 5 | The pubic tubercle:a CT landmark in groin hernia显示文摘 | Delabrousse E Denue PO Aubry S | 2007 | Abdom Imaging2007，32，： | 1 |
| 6 | Value of the small bowel feces sign at CT in adhesive small bowel obstruction显示文摘 | Delabrousse E Baulard R Sarlieve P | 2005 | Radiologic Practice2005，86，： | 1 |
| 7 | Imaging aspects and non-surgical interventional treatment in human alveolar echinococcosis显示文摘 | Solange Bresson-Hadni Eric Delabrousse Oleg Blagosklonov Brigitte Bartholomot Stéphane Koch Jean-Philippe Miguet Georges André Mantion Dominique Angèle Vuitton | 2005 | Parasitology International2005，，： | 1 |
| 8 | Value of the pubic tubercle as a CT reference point in groin hernias显示文摘 | Delabrousse E Michalakis D Sarliève P | 2005 | J Radiol2005，86，61： | 1 |
| 9 | CTof small bowel obstruction in adults 显示文摘 | Delabrousse E Destrumelle N Brunelle S | 2003 | Abdeom Imaging2003，28，： | 1 |
| 10 | The pubic tubercle: a CT landmark in groin hernia 显示文摘 | Delabrousse E Denue PO Aubry S | 2007 | Abdom Imaging2007，32，： | 1 |
| 11 | CT of small bowel obstruction in adults显示文摘 | Delabrousse E Destrumelle N Brunelle S | 2003 | Abdom Imagine2003，28，2： | 1 |
| 12 | CT of small bowel obstruction in adults显示文摘 | Delabrousse E Destrumelle N Brunelle S | | 0，，02： | 1 |
| 13 | Small-bowel bezoar versus small-bowel feces:CT evaluation显示文摘 | Delabrousse E Lubrano J Sailley N | 2008 | AJR Am J Roentgenol2008，191，5： | 1 |
| 14 | Value of the pubic tubercle as a CT reference point in groin hernias显示文摘 | Delabrousse E Miehalakis D Sarlieve P | 2005 | J Radiol2005，86，6： | 1 |
| 15 | Metronomic cyclophosphamide: An alternative treatment for hepatic epithelioid hemangioendothelioma显示文摘 | Zaher Lakkis Stefano Kim Eric Delabrousse Marine Jary Thierry Nguyen Georges Mantion Bruno Heyd Catherine Lassabe Christophe Borg | 2013 | Journal of Hepatology2013，，6： | 1 |
| 16 | Gallstone ile-us:CT findings显示文摘 | Delabrousse E Bartholomot B sohm O | 2000 | Eur Radiol2000，10，6： | 1 |
| 17 | Strangulated transomental hernia: CT findings显示文摘 | E. Delabrousse M. Couvreur O. Saguet B. Heyd S. Brunelle B. Kastler | 2001 | Abdominal Imaging2001，，1： | 1 |
| 18 | Gallstone ileus: CT findings 显示文摘 | Delabrousse E Bartholomot B Sohm O | 2000 | Eur Radiol2000，10，6： | 1 |
| 19 | CT of small bowel obstruction in adults 显示文摘 | Delabrousse E Destrumelle N Brunelle S | 2003 | Abdom Imaging2003，28，2： | 1 |
| 20 | An evalua-tion of the EOS X-ray imaging system in pelvimetry 显示文摘 | Sigmann MH Delabrousse E Riethmuller D | 2014 | DiagnInterv Imaging2014，95，9： | 1 |
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