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| 1 | MdMYB6 regulates anthocyanin formation in apple both through direct inhibition of the biosynthesis pathway and through substrate removal显示文摘Anthocyanin biosynthesis and sugar metabolism are important processes during plant growth,but the molecular interactions underlying these pathways are still unclear.In this work,we analyzed the anthocyanin and soluble sugar contents,as well as the transcript levels of transcription factors that are known to be related to the biosynthesis of anthocyanin in‘Hongcui 1’apple flesh during fruit development.Overexpression of MdMYB6 in red-fleshed calli was found to reduce anthocyanin content and result in downregulated expression of the MdANS and MdGSTF12 proteins.Yeast one-hybrid and electrophoretic mobility shift analyses showed that MdMYB6 could directly bind to the promoters of MdANS and MdGSTF12,indicating that MdMYB6 could inhibit anthocyanin biosynthesis by regulating MdANS and MdGSTF12.Overexpression of MdTMT1 in the Arabidopsis tmt1 mutant restored the glucose and fructose contents to the wild-type levels,while overexpression of MdTMT1 in red-fleshed calli increased the contents of glucose and fructose but reduced the contents of UDP-glucose,UDP-galactose,and anthocyanin.Using a GUS reporter system,yeast one-hybrid,chromatin immunoprecipitation-PCR and electrophoretic mobility shift analyses,we found that MdMYB6 could bind to the promoter of MdTMT1,resulting in increased promoter activity.Overexpression of MdMYB6 in calli overexpressing MdTMT1 increased the expression of MdTMT1,which led to reduced contents of UDP-glucose and UDP-galactose and decreased anthocyanin content compared to those of the calli that overexpressed MdTMT1.This finding suggested that MdMYB6 could also inhibit anthocyanin biosynthesis by regulating MdTMT1 to decrease the contents of UDP-glucose and UDP-galactose.Taken together,these results showed that MdMYB6 and MdTMT1 play key roles in both anthocyanin biosynthesis and sugar transport. | Haifeng Xu Qi Zou Guanxian Yang Shenghui Jiang Hongcheng Fang Yicheng Wang Jing Zhang Zongying Zhang Nan Wang Xuesen Chen | 2020 | Horticulture Research2020，7，1： | 6 |
| 2 | Research on paleo-fluid sources and hydrocarbon preservation conditions in marine carbonates inthe central Yangtze,China显示文摘87Sr/86Sr,δ18O andδ13C ratios of calcite,dolomite,gypsum filling vugs and fissures in marine carbonates and their host rocks from the Sinian to the middle Triassic,are employed to trace the possible source and migration path of key fluids related to development of hydrocarbon,hydrocarbon preservation condition are then discussed further.Comprehensive research,based on the paleo-fluid,the property of formation water and the deformation intensity etc.,indicates that the preservation conditionsin the Shizhu synclinorium zone and Fangdoushan anticlinorium zone are the most predominant in the central Yangtze.Three sets of fluid systems in the Shizhu synclinorium zone are identified.Little fluid exchange occurs between the upper-middle fluid system and the lower fluid system,so two independent preservation units have developed.Both the Permian and the Triassic in the upper preservation unitsand the Dengying Formation of the Sinian and the lower Cambrian in the lower preservation units havegood preservation conditions.The preservation condition in the lower association(Z-S)located in the Huaguoping synclinorium zone in the western Hubei and Hunan is better than that in other tectonic units,where the fluids in the lower association migrated vertically across strata when the fluid isolating intervalswere destroyed,the regional seals are absent and the conditions for the preservation of hydrocarbon accumulations are totally destroyed.The preservation condition is increasingly more favorable from the western Jiangxi and Hunan to the western Hubei&eastern Chongqing on the whole. | Wang Guozhi Xu Guosheng Yuan Haifeng Hu Xiaofeng Zou Can | 2011 | Petroleum Science2011，8，3： | 4 |
| 3 | In-situ Synthesis and Characterization of Poly(vinyl alcohol)/Hydroxyapatite Composite Hydrogel by Freezing-thawing Method显示文摘Poly(vinyl alcohol)/hydroxyapatite(PVA/HA) composite hydrogel was successfully in-situ synthesized via three cycles of freezing-thawing. The composition and structure of products were investigated by X-ray diffraction( XRD), Fourier transformed infrared spectroscopy(FTIR) and scanning electron microscopy(SEM). The influence of different preparation methods and contents of material on the mechanical properties of PVA/HA composite hydrogel was discussed through tensile and compressive tests. The template of PVA could avoid the agglomeration of HA particles, which improves the mechanical properties of the composite hydrogel effectively. The tensile strength, modulus and compressive performances of the PVA/HA composite hydrogel prepared by the in-situ synthesis method were better than those of hydrogel obtained by the simple blend metliod. In addition, the effect of the content of PVA, HA, and the pH value on tlie properties of tlie PVA/HA composite hydrogel has been discussed in detail. | MENG Deyue ZHOU Xiuqing ZHENG Keyan MIAO Chong SHENG Ye ZOU Haifeng | 2019 | Chemical Research in Chinese Universities2019，35，3： | 3 |
| 4 | Influences of Re on low-cycle fatigue behaviors of single crystal superalloys at intermediate temperature显示文摘Low-cycle fatigue behaviors of Ni-base single crystal superalloys containing different Re contents have been investigated at 760℃. During heat treatment. Reretards γ phases coarsening and equalizes the distribution of γ' phases. As Re content increases, fatigue life increases and slip bands distribute more inhomogeneously. Moreover, adding Re not only reduces stacking fault energy of the matrix, but also promotes the element segregation to increase the lattice misfit. However, the larger lattice misfit does not lead to the formation of dislocation networks, but which activates dislocation movement and promotes dislocations cross-slip and climbing movement under high temperature and applied stress. On the other hand, with the addition of Re, cyclic deformation behaviors change from cyclic hardening to cyclic stability, mainly depending on a transformation of deformation mechanisms from slip bands cutting through γ and γ' phases to stacking faults shearing. | Liu Liu Jie Meng Jinlai Liu Mingke Zou Haifeng Zhang Xudong Sun Yizhou Zhou | 2019 | Journal of Materials Science & Technology2019，35，9： | 2 |
| 5 | Preparation and Properties of Silica Nanoparticles from Oil Shale Ash显示文摘 | Gao Guimei Zou Haifeng Gan Shucai etal | 2009 | Powder Technology2009，，191： | 1 |
| 6 | MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7显示文摘 | Qiang Li Chaoxia Zou Chendan Zou Zhongjing Han Haifeng Xiao Huiyan Wei Wei Wang Lei Zhang Xueying Zhang Qingchao Tang Chunjing Zhang Ji Tao Xishan Wang Xu Gao | 2013 | Cancer Letters2013，，： | 1 |
| 7 | Preparation and Properties of Silica Nanoparticles from Oil Shale Ash显示文摘 | Gao Guimei Zou Haifeng Gan Shucai | 2009 | Pow- der Technol2009，191，12： | 1 |
| 8 | Grape-seed proanthocyanidins ameliorate contact hypersensitivity induced by 2,4-dinitrofluorobenzene (DNFB) and inhibit T cell proliferation in vitro显示文摘 | Qiuqiong Tang Peng Zou Haifeng Jin Jun Fu Jintao Yang Lanqin Shang Xuetao Wei | 2012 | Toxicology Letters2012，，： | 1 |
| 9 | Influence of Surfactant Surface Coverage and Aging Time on Physical Properties of Silica Nanoparticles显示文摘 | Gao Guimei Zou Haifeng Liu Darui | 2009 | Colloids and Surfaces2009，350，： | 1 |
| 10 | MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7显示文摘 | Qiang Li Chaoxia Zou Chendan Zou Zhongjing Han Haifeng Xiao Huiyan Wei Wei Wang Lei Zhang Xueying Zhang Qingchao Tang Chunjing Zhang Ji Tao Xishan Wang Xu Gao | 2013 | Cancer Letters2013，，1： | 1 |
| 11 | Structural,dielectric and magnetic properties of Nd-doped CO2 Z-type hexaferrites显示文摘 | XU Jijing JI Guijuans ZOU Haifeng | 2011 | Journal of Alloys and Compounds2011，509，11： | 1 |
| 12 | Preparation and properties of silica nanoparticles from oil shale ash显示文摘 | Gao Guimei Zou Haifeng Gan Shucai | 2009 | Powder Techn2009，191，1： | 1 |
| 13 | Green light emission by Ce 3+ and Tb 3+ co-doped Sr 3 MgSi 2 O 8 phosphors for potential application in ultraviolet whitelight-emitting diodes显示文摘 | Hong Yu Wenwen Zi Shi Lan Shucai Gan Haifeng Zou Xuechun Xu Guangyan Hong | 2012 | Optics and Laser Technology2012，，7： | 1 |
| 14 | Relationship between brachial-ankle pulse wave velocity and metabolic syndrome components in a Chinese population显示文摘The purpose of this study was to assess the relationship between arterial stiffness,as measured by brachial-ankle pulse wave velocity(baPWV),and the presence of the metabolic syndrome(MS)in a Chinese population.A total of 4,445 subjects were enrolled.The prevalence of MS in our study population was 21.7%,17.2%and 25.6%for the general population,males and females,respectively.With adjustments for age,gender,cigarette smoking,heart rate,total cholesterol,low-density lipoprotein(LDL)cholesterol,and the use of anti-hypertensive drug,the stepwise regression analysis showed that baPWV had a significant relationship with components of MS,including systolic blood pressure(P<0.001),diastolic blood pressure(P<0.001),glucose(P<0.001),highdensity lipoprotein(HDL)cholesterol(P=0.04),and triglycerides(P<0.001),but no relationship with waist circumference(P=0.25).With an increase in the number of the MS components,baPWV increased significantly both in women and men.This study indicated that the MS is indeed a risk factor for arterial stiffness.Monitoring of baPWV in patients with MS may help in identifying persons at high risk for cardiovascular disease. | Fang Zhou Haifeng Zhang Wenming Yao Hongbin Mei Dongjie Xu Yanhui Sheng Rong Yang Xiangqing Kong Liansheng Wang Jiangang Zou Zhijian Yang Xinli Li | 2014 | The Journal of Biomedical Research2014，28，4： | 1 |
| 15 | Design and characterization of metallic glass/graphene multilayer with excellent nanowear properties显示文摘The excellent properties of metallic glass(MG)films make them perfect candidates for the use in miniature systems and tools.However,their high coefficients of friction(COFs)and poor wear resistance considerably limit their long-term performance in nanoscale contact.We report the fabrication of a MG/graphene multilayer by the repeated deposition of Cu_(50)Zr_(50) MG with alternating layers of graphene.The microstructure of the multilayer was characterized by the transmission electron microscopy(TEM).Its mechanical and nanotribological properties were studied by nanoindentation and nanoscratch tests,respectively.A molecular dynamics(MD)simulation revealed that the addition of graphene endowed the MG with superelastic recovery,which reduced friction during nanoscratching.In comparison with the monolithic MG film,the multilayer exhibited improved wear resistance and a low COF in repeated nanowear tests owing to the enhanced mechanical properties and lubricating effect caused by the graphene layer.This work is expected to motivate the design of other novel MG films with excellent nanowear properties for engineering applications. | Qing ZHOU Dawei LUO Dongpeng HUA Wenting YE Shuo LI Qiguang ZOU Ziqiang CHEN Haifeng WANG | 2022 | Friction2022，10，11： | 1 |
| 16 | Near-infrared photothermal release of hydrogen sulfide from nanocomposite hydrogels for anti-inflammation applications显示文摘A novel near-infrared light photothemal-activated H2S-donating nanocomposite hydrogel was developed,through combination of a thermo-labile H2S donor and photothermal nanoparticles in agarose hydrogel.The polyethylenimine dithiocarbamate polymer,a thermo-labile compound,was synthesized as a novel H2S donor.The combination of a thermo-labile hydrogen sulfide donor and photothermal nanoparticles enabled the generation of H2S in agarose hydrogel upon irradiation with near-infrared light.The ability to modulate the photoirradiation for controlled generation and spatiotemporally release of H2S are its specific advantages.This photothermal spatiotemporally controlled H2S-releasing strategy was successfully applied to anti-inflammation treatment in a rat model,demonstrating its utility as a novel H2S-based therapeutic approach. | Yan Huang Haifeng Li Xiaoxiao He Xiaohai Yang Li Li Songyang Liu Zhen Zou Kemin Wang Jianbo Liu | 2020 | Chinese Chemical Letters2020，31，3： | 1 |
| 17 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 18 | A Self-Powered Optogenetic System for Implantable Blood Glucose Control显示文摘Diabetes treatment and rehabilitation are usually a lifetime process.Optogenetic engineered designer cell-therapy holds great promise in regulating blood glucose homeostasis.However,portable,sustainable,and long-term energy supplementation has previously presented a challenge for the use of optogenetic stimulation in vivo.Herein,we_purpose a self-powered optogenetic system(SOS)for implantable blood glucose control.The SOS consists of a biocompatible far-red light(FRL)source,FRL-triggered transgene-expressing cells,a power management unit,and a flexible implantable piezoelectric nanogenerator(i-PENG)to supply long-term energy by converting biomechanical energy into electricity.Our results show that this system can harvest energy from body movement and power the FRL source,which then significantly enhanced production of a short variant of human glucagon-like peptide 1(shGLP-1)in vitro and in vivo.Indeed,diabetic mice equipped with the SOS showed rapid restoration of blood glucose homeostasis,improved glucose,and insulin tolerance.Our results suggest that the SOs is sufficiently effective in self-powering the modulation of therapeutic outputs to control glucose homeostasis and,furthermore,present a new strategy for providing energy in optogenetic-based cell therapy. | Zhuo Liu Yang Zhou Xuecheng Qu Lingling Xu Yang Zou Yizhu Shan Jiawei Shao Chan Wang Ying Liu Jiangtao Xue Dongjie Jiang Yubo Fan Zhou Li Haifeng Ye | 2022 | Research2022，，4： | 0 |
| 19 | Larvicidal activity and microencapsulation of tobacco(Nicotiana tabacum)extract on Malacosoma neustria testacea larvae显示文摘To understand and improve the stability of the insecticidal activity of tobacco extract,the 3 rd instar larvae of Malacosoma neustria testacea was determined by the leaf film method.Spectrophotometry identified extract effects on activities of several enzymes.In addition,to improve the stability of the extract,microcapsules were prepared by complex coacervation and phase separation with the extract as core material,and gelatin and gum arabic as wall material.With the embedding rate as the evaluation index,the response surface method was used to optimize the preparation process of the microcapsules.The results show that the extract had a strong insecticidal activity on the larvae,with inhibitory effects on several enzymes examined of carboxylesterase,acetylcholinesterase,glutathione-S transferase,catalase,and superoxide dismutase.The inhibition rate increased with time.The best preparation process of tobacco extract microcapsules was 25% mass fraction of emulsifier,2.05% mass fraction of gelatin,3% mass fraction of gum arabic,1.34 wall core ratio,36 min of complex coacervation time.The embedding rate was 58.4% which is approximately the theoretical embedding rate(58.9%).The microcapsules prepared by this method have a smooth surface,good combining form and particle size distribution,and a median diameter of 8.6 μm.Infrared characteristic peaks of the extracts were preserved at 877.55 cm^(-1) and2922.13 cm^(-1).Microencapsulation can improve the thermal stability of the tobacco extract.Indoor toxicity tests showed that LC_(50) of extract microcapsules was 20.2 mg·mL^(-1),equivalent to the toxicity level of the tobacco extract itself,indicating that microencapsulation did not reduce extract insecticidal effects.This research may provide a reference for the optimization of the tobacco extract microcapsule preparation process. | Yunze Chen Jing Yang Guocai Zhang Bowen Zhang Jianyong Zeng Haifeng Zou Tao Li | 2021 | Journal of Forestry Research2021，32，4： | 0 |
| 20 | Genesis and significance of quartz cement in sandstones显示文摘Quartz cement as syntaxial overgrowths is one of the most abundant cements in sandstones. Distribution of quartz cement in time and space indicates that the more younger the stratigraphy is, the more smaller the amount of quartz cement, and the amount of quartz cement increases with increasing of depth and basin type also is a factor which controls the amount of quartz cement. The sources of silica for quartz cement have many different opinions, but there is one or more dominant sources. Temperature and pH of fluid are major factors which influence the precipitation of quartz cement. There exist three hypotheses on the flow of pore fluid and transport and precipitation of silica, that is, the hypothesis of cycle of shallow underground water, the hypothesis of high concentration of fluid driven by compaction and the hypothesis of diffusion and recycle of local fluid. The research of quartz cement is significant for the timing of paleotemperature, heterogeneity of reservoir, physical property of reservoir and the timing of oil immersion, etc. | Yu Junmin, Liu li, Gao Fuhong and Zou Haifeng (Changchun University of Science and Technology, Changchun 130026) Yang Yongchang, Sun Xiaoming and Zhang Liqin (Geology and Development Institute,Dagang Oil Field Group Ltd., Tianjin 300280) | 1999 | Global Geology1999，4，1： | 0 |
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