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| 1 | Torque teno virus:Its prevalence and isotypes in North India显示文摘AIM: To investigate the prevalence and genotype dis-tribution of Torque teno virus (TTV) in patients with different liver diseases and chronic renal failure treated at a referral hospital in North India. METHODS: Whereas prevalence of TTV was based on amplification of conserved region of ORF2 of TTV genome,the genotyping of TTV was carried out using restriction fragment length polymorphism (RFLP) procedure on the N22 region of ORF1. RESULTS: TTV-DNA was detected in 137 of 513 (26.7%) patients with liver diseases and 38 of 65 (58.5%) patients with chronic renal failure. TTV was also detected in 27% of healthy controls. The sequence analysis of the PCR product from 10 randomly selected cases failed to show a significant sequence divergence when compared with that of the TRM1 isolate of TTV genotype 1. The results of genotyping in 55 randomly selected patients showed the presence of genotype 1 (G1) in 53 (96.4%) and genotype 2 (G2) in 2 cases (3.6%),respectively. Other genotypes were not identified in this patient subgroup,suggesting that G1 is predominant in this area. The results of genotyping by RFLP were also supported by phylogenetic tree analysis,where G1 was found to be the major genotype. CONCLUSION: These results indicate that TTV is moderately present in Indian patients,with G1 to be the major genotype in North India. The pathogenicity and etiological role of TTV in different diseases is still a question mark and warrant further studies. | Mohammad Irshad Shiwani Singh Khushboo Irshad Sanjay Kumar Agarwal Yogendra Kumar Joshi | 2008 | World Journal of Gastroenterology2008，14，39： | 5 |
| 2 | Evaluation of cytotoxic and anti-tumor activity of partially purified serine protease isolate from the Indian earthworm Pheretima posthuma显示文摘Objective:To isolate,partially purify and evaluate the cytotoxic and antitumor activity of a serine protease from the chosen Indian earthworm Pheretima posthuma.Methods:Whole animal extract was prepared and purified its protein constituents by size and charge based chromatographic separation techniques using Sephadex G-50 and DEAE-Cellulose resin respectively.Average molecular weight of the protein isolate was determined and analyzed for its cytotoxic property against Vero cells in different dilutions(1:20 and 1:40)and anti-tumor activity by MTT assay(a colorimetric assay)using breast cancer cell line MCF-7,with tamoxifen as standard.Results:One of the protein constituents after purification was characterized as serine protease by Caseinolytic plate diffusion assay.Average molecular weight of this purified isolate was determined,by SDS-PAGE analysis with standard protein ladder,as of 15 kDa.The performed tests suggested that the 15kDa fraction has potent cytotoxic activity and satisfactory antitumor activity as well in vitro.Conclusions:Exact molecular mechanism of the cytotoxic and antitumor activities is yet to be explored and currently we are working on ultra-purification and biophysical characterization of this fraction.Further investigation into the mechanism(s)of cytotoxic and antitumor activities at molecular level would be useful in treatment of various classes of cancer and viral infections in future. | Mahendra Kumar Verma Francies Xavier Yogendra Kumar Verma Kota Sobha | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，11： | 3 |
| 3 | Early Enteral Nutrition in Severe Acute Pancreatitis: A Prospective Randomized Controlled Trial Comparing Nasojejunal and Nasogastric Routes显示文摘 | Ajay Kumar Namrata Singh Shyam Prakash Anoop Saraya Yogendra Kumar Joshi | 2006 | Journal of Clinical Gastroenterology2006，，5： | 2 |
| 4 | Dietary Counseling Versus Dietary Supplements for Malnutrition in Chronic Pancreatitis: A Randomized Controlled Trial显示文摘 | Siddharth Singh Shallu Midha Namrata Singh Yogendra Kumar Joshi Pramod Kumar Garg | 2008 | Clinical Gastroenterology and Hepatology2008，，3： | 1 |
| 5 | Subcritical water extraction of antioxidant compounds from Seabuckthorn (Hippopkae rkamnoides) leaves for the comparative evaluation ofantioxidant activity显示文摘 | YOGENDRA KUMAR M S RUMA D DIPTI P | 2011 | Food Chem2011，，127： | 1 |
| 6 | Subcritical water extraction of antioxidant compounds from Seabuckthorn (Hippopkae rkamnoides) leaves for the comparative evaluation ofantioxidant activity显示文摘 | YOGENDRA KUMAR M S RUMA D DIPTI P | 2011 | Food Chem2011，，127： | 1 |
| 7 | Dietary Counseling Versus Dietary Supplements for Malnutrition in Chronic Pancreatitis: A Randomized Controlled Trial显示文摘 | Siddharth Singh Shallu Midha Namrata Singh Yogendra Kumar Joshi Pramod Kumar Garg | 2008 | Clinical Gastroenterology and Hepatology2008，，3： | 1 |
| 8 | Genetic algorithm for supply restoration in distribution system with priority customers 显示文摘 | Yogendra Kumar Biswamp Das Jaydev Sharma | 2006 | 9th international conference on probabilistic methods applied to power systems KTH Stockholm Sweden June 11-152006，，： | 1 |
| 9 | Antioxidant, cytoprotective and antibacterial effects of Sea buckthorn ( Hippophae rhamnoides L.) leaves显示文摘 | Nitin K. Upadhyay M.S. Yogendra Kumar Asheesh Gupta | 2010 | Food and Chemical Toxicology2010，，12： | 1 |
| 10 | Multi-objective, Multi-constraint Service Restoration of Electric Power Distribution System With Priority Customers 显示文摘 | Yogendra Kumar Biswarup Das and Jaydev Sharma | 2008 | IEEE Trans on Power Delivery2008，23，1： | 1 |
| 11 | Polyethylenimine nanoparticles as efficient transfecting agents for mammalian cells显示文摘 | Surendra Nimesh Anita Goyal Vikas Pawar Sujatha Jayaraman Pradeep Kumar Ramesh Chandra Yogendra Singh Kailash C. Gupta | 2005 | Journal of Controlled Release2005，，2： | 1 |
| 12 | A simple and rapid spectrophotometric method for the determination of nitrite by its decolorizing effect on peroxovanadate complex 显示文摘 | ABDUL GALIL M S MAHADEVAIAH YOGENDRA KUMAR M S | 2007 | Spectrochim Acta Part A2007，67，1： | 1 |
| 13 | Comparative Studies of Different Organs of Nyctanthes arbortristis in Modulation of Cytokines in Murine Model of Arthritis显示文摘Objective To study the modulation effect of pro-and anti-inflammatory cytokines following long term use of water soluble ethanol extracts from different organs of Nyctanthes arbortristis(NAT) in mouse model of arthritis. Methods Arthritis was induced in mice by two injections of Freund's complete adjuvant on days 0 and 12 in the sub-planter surface of the right hind paw. Results Injection of adjuvant resulted in a maximum primary edema of the footpad with erythema,and edema and distortion of joints of the right hind paw after 24-48 hours. Second injection of FCA led to the formation of secondary swellings persisting more than four weeks that spread onto the other hind limb but to a lesser extent. Histological analysis of the ankle on day 47 showed marked evidence of cartilage destruction in association with pannus formation and moderate bone resorption. Proinflammatory cytokine levels in the inflamed joint homogenate were elevated on days 2,14,and 47. Oral administration of leaf and fruit extracts in arthritic mice reduced joint homogenate levels of tumor necrosis factor-α,interleukin-1β,and interleukin-6 on days 2,14,and 47 in comparison to untreated arthritic mice. Interleukin-10 level was elevated in the inflamed joint on days 2,14,and 47 in comparisons to untreated arthritic mice. Conclusion Evidence of lesser inflammation of the footpad and joint and associated histological observation support the therapeutic benefit of leaf and fruit extracts from Nyctanthes arbortristis. This study helps in understanding the mechanism of anti-inflammatory action of Nyctanthes arbortristis in the light of pro-and anti-inflammatory cytokine balance. | BRIJESH RATHORE BHOLANATH PAUL BHUSAN P CHAUDHURY ASHOK KUMAR SAXENA ANAND PRAKASH SAHU YOGENDRA KUMAR GUPTA | 2007 | Biomedical and Environmental Sciences2007，20，2： | 1 |
| 14 | Analytical Study of Planar Waveguide Sensor With a Metamaterial Guiding Layer显示文摘作为指导层有 metamaterial 的三层、四层的平面波导传感器的敏感为事件光并且与存在结果相比的 p 极化被分析。建议传感器表演为盖子层的每个盒子改进了盖子层敏感折射索引。另外,建议传感器为 adlayer 厚度和 adlayer 的不同价值表明改进 adlayer 敏感折射索引。metamaterial 由于它的异乎寻常的性质增加了迅速凋落的领域,这被观察,由哪个盖子层敏感以及 adlayer 敏感的价值被提高。 | Anurag UPADHYAY Yogendra Kumar PRAJAPATI Rajeev TRIPATHI | 2017 | Photonic Sensors2017，7，4： | 1 |
| 15 | Multiobjective,muiticonstraint service restoration of electric power distribution system with priority customers显示文摘 | Yogendra Kumar Biswarup Das Jaydev Sharma | 2008 | IEEE Trans on Power Delivery2008，23，1： | 1 |
| 16 | Antioxidant and hepatoprotective activities of phenolic rich fraction of Seabuckthorn ( Hippophae rhamnoides L.) leaves显示文摘 | D.T. Maheshwari M.S. Yogendra Kumar Saroj K. Verma Vijay K. Singh Som Nath Singh | 2011 | Food and Chemical Toxicology2011，，9： | 1 |
| 17 | Expression of accessory colonization factor subunit A (ACFA) of Vibrio cholerae and ACFA fused to cholera toxin B subunit in transgenic tomato ( Solanum lycopersicum )显示文摘 | Manoj Kumar Sharma Dewal Jani M. Thungapathra J.K. Gautam L.S. Meena Yogendra Singh Amit Ghosh Akhilesh Kumar Tyagi Arun Kumar Sharma | 2008 | Journal of Biotechnology2008，，1： | 1 |
| 18 | Effect of leaf extract of Seabuckthorn on lipopolysaccharide induced inflammatory response in murine macrophages显示文摘 | Yogendra Padwad Lilly Ganju Monika Jain Sudipta Chanda Dev Karan Pratul Kumar Banerjee Ramesh Chand Sawhney | 2005 | International Immunopharmacology2005，，1： | 1 |
| 19 | Multi- objective, multi-constraint service restoration of electric power distribution system with priority customers显示文摘 | Yogendra Kumar Biswarup Das Jaydev Sharma | 2008 | IEEE Trans on Power Delivery2008，23，1： | 1 |
| 20 | Intestinal permeability and complications in liver cirrhosis: A prospective cohort study显示文摘 | Jaya Benjamin Vikas Singla Indu Arora Seema Sood Yogendra Kumar Joshi | 2012 | Hepatology Research2012，，2： | 1 |
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