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| 1 | The Genome of Artemisia annua Provides Insight into the Evolution of Asteraceae Family and Artemisinin Biosynthesis显示文摘Artemisia annua,通常已知的同样香甜的苦恼或 Qinghao,是到中国的一个灌木土著人并且长被用于药用的目的。A。annua 现在作为有势力抗疟药混合物的唯一的生来的来源全球性被栽培, artemisinin。这里,我们报导 A 的 1.74-gigabase 染色体的一个高质量的草稿集会。annua,高度异质接合,富于重复定序,并且包含 63 ? 226 编码蛋白质的基因,在定序的植物种类之中的最大的数字之一。我们发现了那,作为在 Asteraceae 的一些定序的染色体之一, A。annua 染色体包含对这大被子植物 clade 特定的很多基因。尤其是,扩大和编码涉及萜烯生合成的酶的基因的功能的多样化与 artemisinin biosynthetic 小径的进化一致。我们进一步由介绍那 A 的 transcriptome 揭示了。annua 发展了复杂 transcriptional 规章的网络位于 \O 下面 artemisinin 生合成。把转基因的 A 基于我们产生了的全面 genomic 和 transcriptomic 分析。artemisinin 高级的生产的 annua 线,它现在为大规模生产准备好了并且将从而帮助遇见增加 artemisinin 的全球需求的挑战。 | Qian Shen Lida Zhang Zhihua Liao Shengyue Wang Tingxiang Yan Pu Shi Meng Liu Xueqing Fu Qifang Pan Yuliang Wang Zongyou Lv Xu Lu Fangyuan Zhang Weimin Jiang Yanan Ma Minghui Chen Xiaolong Hao Ling Li Yueli Tang Gang Lv Yan Zhou Xiaofen Sun Peter E. Brodelius Jocelyn K.C. Rose Kexuan Tang | 2018 | Molecular Plant2018，11，6： | 47 |
| 2 | Inulin Can Alleviate Metabolism Disorders in ob/ob Mice by Partially Restoring Leptinrelated Pathways Mediated by Gut Microbiota显示文摘Inulin has been used as a prebiotic to alleviate glucose and lipid metabolism disorders in mice and humans by modulating the gut microbiota. However, the mechanism underlying the alleviation of metabolic disorders by inulin through interactions between the gut microbiota and host cells is unclear. We use ob/ob mice as a model to study the effect of inulin on the cecal microbiota by16 S rRNA gene amplicon sequencing and its interaction with host cells by transcriptomics. The inulin-supplemented diet improved glucose and lipid metabolism disorder parameters in ob/ob mice,alleviating fat accumulation and glucose intolerance. The a diversity of gut microbial community of ob/ob mice was reduced after inulin treatment, while the b diversity tended to return to the level of wild type mice. Interestingly, Prevotellaceae UCG 001(family Prevotellaceae) was obviously enriched after inulin treatment. A comparative analysis of the gene expression profile showed that the cecal transcriptome was changed in leptin gene deficiency mice, whereas the inulin-supplemented diet partially reversed the changes in leptin gene-related signaling pathways, especially AMPK signaling pathway, where the levels of gene expression became comparable to those in wild type mice.Further analysis indicated that Prevotellaceae UCG 001 was positively correlated with the AMPK signaling pathway, which was negatively correlated with markers of glycolipid metabolism disorders. Our results suggest that the inulin-supplemented diet alleviates glucose and lipid metabolism disorders by partially restoring leptin related pathways mediated by gut microbiota. | Xiaofeng Song Liang Zhong Na Lyu Fei Liu Boxing Li Yanan Hao Yong Xue Jing Li Yuqing Feng Yue Ma Yongfei Hu Baoli Zhu | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 12 |
| 3 | High-speed image reconstruction for optically sectioned,super-resolution structured illumination microscopy显示文摘Super-resolution structured illumination microscopy(SR-SIM)is an outstanding method for visualizing the subcellular dynamics in living cells.To date,by using elaborately designed systems and algorithms,SR-SIM can achieve rapid,optically sectioned,SR observation with hundreds to thousands of time points.However,real-time observation is still out of reach for most SIM setups as conventional algorithms for image reconstruction involve a heavy computing burden.To address this limitation,an accelerated reconstruction algorithm was developed by implementing a simplified workflow for SR-SIM,termed joint space and frequency reconstruction.This algorithm results in an 80-fold improvement in reconstruction speed relative to the widely used Wiener-SIM.Critically,the increased processing speed does not come at the expense of spatial resolution or sectioning capability,as demonstrated by live imaging of microtubule dynamics and mitochondrial tubulation. | Zhaojun Wang Tianyu Zhao Huiwen Hao Yanan Cai Kun Feng Xue Yun Yansheng Liang Shaowei Wang Yujie Sun Piero RBianco Kwangsung Oh Ming Lei | 2022 | Advanced Photonics2022，4，2： | 9 |
| 4 | Outcome of multimodal MRI-guided intravenous thrombolysis in patients with stroke with unknown time of onset显示文摘Objective Intravenous tissue plasminogen activator(tPA)is the standard therapy for patients with acute ischaemic stroke(AIS)within 4.5 hours of onset.Recent trials have expanded the endovascular treatment window to 24 hours.We investigated the efficacy and safety of using multimodal MRI to guide intravenous tPA treatment for patients with AIS of unknown time of onset(UTO).Methods Data on patients with AIS with UTO and within 4.5 hours of onset were reviewed.Data elements collected and analysed included:demographics,National Institutes of Health Stroke Scale(NIHSS)score at baseline and 2 hours,24 hours,7 days after thrombolysis and before discharge,the modified Rankin Scale(mRS)score at 3 months after discharge,imaging findings and any adverse event.results Forty-two patients with UTO and 62 in control group treated within 4.5 hours of onset were treated with intravenous tPA.The NIHSS scores after thrombolysis and/or before discharge in UTO group were significantly improved compared with the baseline(p<0.05).Between the two groups,no significant differences in NIHSS score were observed(p>0.05).Utilising the non-inferiority test,to compare mRS scores(0-2)at 3 months between the two groups,the difference was 5.2%(92%CI,OR 0.196).Patients in the UTO group had mRS scores of 0-2,which were non-inferior to the control group.Their incidence of adverse events was similar.Conclusions Utilising multimodal MRI to guide intravenous only thrombolysis for patients with AIS with UTO was safe and effective.In those patients with AIS between 6 and 24 hours of time of onset but without large arterial occlusion,intravenous thrombolysis could be considered an option. | Jie Zhao Hongmei Zhao Runtao Li Jiangtao Li Chang Liu Juan Lv Yanan Li Wei Liu Dongpu Ma Huaihai Hao Xinguang Xiao Junzhong Liu Yongfeng Yin Rongli Liu Qiaoyan Yu Yingjie Wei Pengyan Li Yue Wang Runqing Wang | 2019 | Stroke & Vascular Neurology2019，4，1： | 8 |
| 5 | Comparison of the protective effects of resveratrol and pterostilbene against intestinal damage and redox imbalance in weanling piglets显示文摘Background: Evidence indicates that early weaning predisposes piglets to intestinal oxidative stress and increases the risk of intestinal dysfunction;however, there are minimal satisfactory treatment strategies for these conditions.This study investigated the potential of resveratrol and its analog, pterostilbene, as antioxidant protectants for regulating intestinal morphology, barrier function, and redox status among weanling piglets.Methods: A total of 144 piglets were selected at 21 days of age and randomly allocated into one of four treatment groups, each of which included six replicates. Piglets in a sow-reared control group were suckling normally between ages 21 and 28 days, while those in weaned groups were fed a basal diet, supplemented with either 300 mg/kg of resveratrol or with 300 mg/kg of pterostilbene. Parameters associated with intestinal injury and redox status were analyzed at the end of the feeding trial.Results: Early weaning disrupted the intestinal function of young piglets, with evidence of increased diamine oxidase activity and D-lactate content in the plasma, shorter villi, an imbalance between cell proliferation and apoptosis, an impaired antioxidant defense system, and severe oxidative damage in the jejunum relative to suckling piglets. Feeding piglets with a resveratrol-supplemented diet partially increased villus height(P = 0.056) and tended to diminish apoptotic cell numbers(P = 0.084) in the jejunum compared with those fed a basal diet. Similarly, these beneficial effects were observed in the pterostilbene-fed piglets. Pterostilbene improved the feed efficiency of weanling piglets between the ages of 21 and 28 days;it also resulted in diminished plasma diamine oxidase activity and D-lactate content relative to untreated weaned piglets(P < 0.05). Notably, pterostilbene restored jejunal antioxidant capacity, an effect that was nearly absent in the resveratrol-fed piglets. Pterostilbene reduced the malondialdehyde and 8-hydroxy-2′-deoxyguanosine contents of jejunal mucosa possibly through its regulatory role in facilitating the nuclear translocation of nuclear factor erythroid-2-related factor 2 and the expression levels of NAD(P)H quinone dehydrogenase 1 and superoxide dismutase 2(P < 0.05).Conclusions: The results indicate that pterostilbene may be more effective than its parent compound in alleviating early weaning-induced intestinal damage and redox imbalance among young piglets. | Hao Zhang Yanan Chen Yueping Chen Shuli Ji Peilu Jia Yue Li Tian Wang | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 8 |
| 6 | A review:Photonics devices,architectures,and algorithms for optical neural computing显示文摘The explosive growth of data and information has motivated various emerging non-von Neumann computational approaches in the More-than-Moore era.Photonics neuromorphic computing has attracted lots of attention due to the fascinating advantages such as high speed,wide bandwidth,and massive parallelism.Here,we offer a review on the optical neural computing in our research groups at the device and system levels.The photonics neuron and photonics synapse plasticity are presented.In addition,we introduce several optical neural computing architectures and algorithms including photonic spiking neural network,photonic convolutional neural network,photonic matrix computation,photonic reservoir computing,and photonic reinforcement learning.Finally,we summarize the major challenges faced by photonic neuromorphic computing,and propose promising solutions and perspectives. | Shuiying Xiang Yanan Han Ziwei Song Xingxing Guo Yahui Zhang Zhenxing Ren Suhong Wang Yuanting Ma Weiwen Zou Bowen Ma Shaofu Xu Jianji Dong Hailong Zhou Quansheng Ren Tao Deng Yan Liu Genquan Han Yue Hao | 2021 | Journal of Semiconductors2021，42，2： | 7 |
| 7 | Recent progress of integrated circuits and optoelectronic chips显示文摘Integrated circuits(ICs)and optoelectronic chips are the foundation stones of the modern information society.The IC industry has been driven by the so-called'Moore's law'in the past 60 years,and now has entered the post Moore's law era.In this paper,we review the recent progress of ICs and optoelectronic chips.The research status,technical challenges and development trend of devices,chips and integrated technologies of typical IC and optoelectronic chips are focused on.The main contents include the development law of IC and optoelectronic chip technology,the IC design and processing technology,emerging memory and chip architecture,brain-like chip structure and its mechanism,heterogeneous integration,quantum chip technology,silicon photonics chip technology,integrated microwave photonic chip,and optoelectronic hybrid integrated chip. | Yue HAO Shuiying XIANG Genquan HAN Jincheng ZHANG Xiaohua MA Zhangming ZHU Xingxing GUO Yahui ZHANG Yanan HAN Ziwei SONG Yan LIU Ling YANG Hong ZHOU Jiangyi SHI Wei ZHANG Min XU Weisheng ZHAO Biao PAN Yangqi HUANG Qi LIU Yimao CAI Jian ZHU Xin OU Tiangui YOU Huaqiang WU Bin GAO Zhiyong ZHANG Guoping GUO Yonghua CHEN Yong LIU Xiangfei CHEN Chunlai XUE Xingjun WANG Lixia ZHAO Xihua ZOU Lianshan YAN Ming LI | 2021 | Science China(Information Sciences)2021，64，10： | 7 |
| 8 | Micro RNA profiles and potential regulatory pattern during the early stage of spermatogenesis in mice显示文摘Spermatogenesis is a complicated and poorly understood process that relies on the precise regulation of the self-renewal and differentiation of spermatogonia. In many organisms, micro RNAs(mi RNAs) are involved in multiple developmental processes as critical regulators of transcriptional and post-transcriptional gene silencing. This study investigated the expression pattern of mi RNAs in type B spermatogonia cells(BSc) and primary spermatocytes(PSc) of mice, using a high-throughput small RNA sequencing system. The results revealed that the expression levels of Let-7 family mi RNAs were remarkably high in both cell types. Furthermore, the expression levels of mi R-21, mi R-140-3p, mi R-103, mi R-30 a, mi R-101 b and mi R-99 b were decreased during the transformation from BSc to PSc. These mi RNAs target vital genes that participate in apoptosis, cell proliferation and differentiation, junction assembly and cell cycle regulation. These results highlight the indispensable role of mi RNAs in spermatogenesis. | LUO MengMeng HAO LiLi HU Fen DONG YaNan GOU LiXia ZHANG WenDian WANG Xin ZHAO YuHui JIA MengChun HU SongNian ZHANG XiuJun | 2015 | Science China(Life Sciences)2015，58，5： | 6 |
| 9 | Generation of multi-channel chaotic signals with time delay signature concealment and ultrafast photonic decision making based on a globally-coupled semiconductor laser network显示文摘We propose and demonstrate experimentally and numerically a network of three globally coupled semiconductor lasers(SLs)that generate triple-channel chaotic signals with time delayed signature(TDS)concealment.The effects of the coupling strength and bias current on the concealment of the TDS are investigated.The generated chaotic signals are further applied to reinforcement learning,and a parallel scheme is proposed to solve the multiarmed bandit(MAB)problem.The influences of mutual correlation between signals from different channels,the sampling interval of signals,and the TDS concealment on the performance of decision making are analyzed.Comparisons between the proposed scheme and two existing schemes show that,with a simplified algorithm,the proposed scheme can perform as well as the previous schemes or even better.Moreover,we also consider the robustness of decision making performance against a dynamically changing environment and verify the scalability for MAB problems with different sizes.This proposed globally coupled SL network for a multi-channel chaotic source is simple in structure and easy to implement.The attempt to solve the MAB problem in parallel can provide potential values in the realm of the application of ultrafast photonics intelligence. | Yanan Han Shuiying Xiang Yang Wang Yuanting Ma Bo Wang Aijun Wen Yue Hao | 2020 | Photonics Research2020，8，11： | 6 |
| 10 | Delay-weight plasticity-based supervised learning in optical spiking neural networks显示文摘We propose a modified supervised learning algorithm for optical spiking neural networks,which introduces synaptic time-delay plasticity on the basis of traditional weight training.Delay learning is combined with the remote supervised method that is incorporated with photonic spike-timing-dependent plasticity.A spike sequence learning task implemented via the proposed algorithm is found to have better performance than via the traditional weight-based method.Moreover,the proposed algorithm is also applied to two benchmark data sets for classification.In a simple network structure with only a few optical neurons,the classification accuracy based on the delay-weight learning algorithm is significantly improved compared with weight-based learning.The introduction of delay adjusting improves the learning efficiency and performance of the algorithm,which is helpful for photonic neuromorphic computing and is also important specifically for understanding information processing in the biological brain. | Yanan Han Shuiying Xiang Zhenxing Ren Chentao Fu Aijun Wen Yue Hao | 2021 | Photonics Research2021，9，4： | 4 |
| 11 | Preliminary Analysis of Diesel-Degrading Bacteria Immobilized on Organic Carriers in Seawater显示文摘Oil pollution in marine environment is becoming increasingly serious. Oil bioremediation by immobilization technology has been widely studied. However, the effect of bacteria immobilization was limited because of lack of nutrients. In this paper, the organic materials(corn straw, corn cob and corn leaf) were used as carriers. The diesel removal rate achieved by the immobilized bacteria was studied, and the effects of nutrients(e.g. nitrogen and phosphorus) released from organic carriers to the immobilized bacteria were analyzed. Test results indicated that a certain amount of nutrients was released from organic carriers. Additionally, the diesel removal rates achieved by different immobilized bacteria were all higher than those achieved by free bacteria. And, the diesel removal rates achieved by bacteria decreased in the following order: bacteria immobilized on corn straw(79%), bacteria immobilized on corn leaf(70%) and bacteria immobilized on corn cob(43%). These findings indicated two aspects, viz.: the carriers porous structure and the nutrients, which were favorable to biodegradation. Finally, the changes in nitrogen and phosphorus contents that were released from different carriers during biodegradation were studied. The results showed that the rate of diesel biodegradation was fast in the initial phase because of the sufficient nutrients released from carriers. Meanwhile, in the final phase, the rate of diesel biodegradation was relatively slow because of few nutrients released from carriers. | Liu Zhixiu Xue Jianliang Wu Yanan Li Menglu Sun Xiyu Cui Hao Cheng Lijie Gao Yu Xiao Xinfeng | 2017 | China Petroleum Processing & Petrochemical Technology2017，19，2： | 4 |
| 12 | Resveratrol and its derivative pterostilbene ameliorate intestine injury in intrauterine growth-retarded weanling piglets by modulating redox status and gut microbiota显示文摘Background:Intestinal disorder is an important factor contributing to growth lag and high rates of morbidity and mortality of piglets with intrauterine growth retardation(IUGR).Resveratrol(RSV)and its derivative pterostilbene(PT)are natural stilbenes possessing various bioactivities,such as antioxidative and anti-inflammatory effects.This study compared the protective potential of RSV and PT on the intestinal redox status and gut microbiota in weanling piglets with IUGR.Methods:Eighteen male piglets of normal body weight(NBW)and 54 same-sex IUGR piglets were chosen according to their birth and weaning weights.The NBW piglets accepted a basal diet,while the IUGR piglets were allotted to one of three groups according to their body weight at weaning and received a basal diet,an RSV-supplemented diet(300 mg/kg),or a PT-supplemented diet(300 mg/kg),respectively.Results:Compared with IUGR piglets,both RSV and PT improved the IUGR-associated decrease in jejunal villus height and increases in plasma diamine oxidase activity and D-lactate level and jejunal apoptosis of piglets(P<0.05).Administering RSV and PT also enhanced jejunal superoxide dismutase activity and the mRNA and protein expression of superoxide dismutase 2 of IUGR piglets by promoting nuclear factor erythroid 2-related factor 2(Nrf2)nuclear translocation(P<0.05).Comparatively,PT was more effective than RSV in elevating the villus height/crypt depth ratio and occludin mRNA and protein levels in the jejunum of IUGR piglets(P<0.05).PT was also superior to RSV in increasing Nrf2 nuclear translocation and inhibiting malondialdehyde accumulation in the jejunum of IUGR piglets(P<0.05).Additionally,RSV modulated the composition of cecal microbiota of IUGR piglets,as evidenced by increasing the prevalence of the phylum Bacteroidetes and the genera Prevotella,Faecalibacterium,and Parabacteroides and inhibiting the growth of the phylum Proteobacteria and its genera Escherichia and Actinobacillus(P<0.05).Moreover,RSV significantly increased the butyrate concentration in the cecum of IUGR piglets(P<0.05).Conclusion:PT is more potent than RSV to prevent intestinal oxidative stress,while RSV has a stronger capacity to regulate gut microbiota compared to PT. | Yanan Chen Hao Zhang Yueping Chen Peilu Jia Shuli Ji Yuying Zhang Tian Wang | 2021 | Journal of Animal Science and Biotechnology2021，12，4： | 3 |
| 13 | A Small-Divergence-Angle Orbital Angular Momentum Metasurface Antenna显示文摘Electromagnetic waves carrying an orbital angular momentum (OAM) are of great interest. However, most OAM antennas presentdisadvantages such as a complicated structure, low efficiency, and large divergence angle, which prevents their practicalapplications. So far, there are few papers and research focuses on the problem of the divergence angle. Herein, a metasurfaceantenna is proposed to obtain the OAM beams with a small divergence angle. The circular arrangement and phase gradient wereused to simplify the structure of the metasurface and obtain the small divergence angle, respectively. The proposed metasurfaceantenna presents a high transmission coefficient and effectively decreases the divergence angle of the OAM beam. All thetheoretical analyses and derivation calculations were validated by both simulations and experiments. This compact structurepaves the way to generate OAM beams with a small divergence angle. | Jianchun Xu Ke Bi Ru Zhang Yanan Hao Chuwen Lan Klaus D.McDonald-Maier Xiaojun Zhai Zidong Zhang Shanguo Huang | 2019 | Research2019，，1： | 3 |
| 14 | Effect of different milling processes on the mineral distribution in a coal powder显示文摘Coal samples obtained from Wanbei(WB),Pingxiang(PX),Liupanshui(LP),and Datong(DT) mines were pulverized,using either a vibration mill or a ball mill,to different degrees of fineness.The effect of the different grinding methods on the mineral distribution within the pulverized coal was investigated by using proximate analysis,particle size analysis,and float-sink tests.The results show that the ash content in WB,PX,and DT coal increases with increasing particle size overall,while the ash content of the LP coal remain almost the same within each size fraction.In that case the ash in each fraction is similar to that of the raw coal.The ash versus size distributions for the same coal sample milled with the same grinding method to different degrees of fineness are similar.The ash versus size distribution of the coal powder with a 15% screen residue that was prepared with the vibration mill is different from the distribution of a similar sample prepared with a ball mill.The curves also vary between different coal samples.The grinding method has a great influence on the distribution of minerals across the various particle sizes.The float-sink tests and the laser particle size analysis results on PX and DT coal samples show that fines dominate the higher density fractions although the large +2.0 g/cm3 fraction was dominated by coarse particles.The size distribution of the low density fraction and +2.0 g/cm3 density fraction is bimodal.The size distribution of the intermediate density fraction is multimodal. | Hao Juan Zhang Hong Yang Keyang Lu Chao ChenJiabao Li Yanan | 2012 | International Journal of Mining Science and Technology2012，22，2： | 3 |
| 15 | Real-time optical spike-timing dependent plasticity in a single VCSEL with dual-polarized pulsed optical injection显示文摘We propose and numerically realize an optical spike-timing dependent plasticity(STDP)scheme by using a single vertical-cavity surface-emitting laser(VCSEL).In the scheme,the VCSEL is subjected to an orthogonally-polarized continuous-wave optical injection(OPCWOI)and dual-polarized pulsed optical injections(DPPOI).Based on the widely used spin-flip model,the response spiking dynamics of VCSEL is numerically studied,and then the optical STDP in a single VCSEL is explored.The roles of bias current,the strength of OPCWOI and DPPOI,and the frequency detuning on the optical STDP curve are numerically analyzed.It is found that,by simultaneously utilizing the response spiking dynamics in two orthogonal polarization modes,an optical STDP could be achieved by using a single VCSEL.Furthermore,the weight update of STDP curve can be calculated in real-time.Additionally,the STDP curves can also be controlled by adjusting some controllable parameters.The real-time optical STDP based on a single VCSEL is numerically realized for the first time,which paves the way towards fully VCSELs-based photonic neuromorphic systems with low power consumption. | Shuiying XIANG Yanan HAN Xingxing GUO Aijun WEN Genquan HAN Yue HAO | 2020 | Science China(Information Sciences)2020，63，6： | 3 |
| 16 | Photonic integrated spiking neuron chip based on a self-pulsating DFB laser with a saturable absorber显示文摘We proposed and experimentally demonstrated a simple and novel photonic spiking neuron based on a distributed feedback(DFB)laser chip with an intracavity saturable absorber(SA).The DFB laser with an intracavity SA(DFBSA)contains a gain region and an SA region.The gain region is designed and fabricated by the asymmetric equivalentπ-phase shift based on the reconstruction-equivalent-chirp technique.Under properly injected current in the gain region and reversely biased voltage in the SA region,periodic self-pulsation was experimentally observed due to the Q-switching effect.The self-pulsation frequency increases with the increase of the bias current and is within the range of several gigahertz.When the bias current is below the self-pulsation threshold,neuronlike spiking responses appear when external optical stimulus pulses are injected.Experimental results show that the spike threshold,temporal integration,and refractory period can all be observed in the fabricated DFB-SA chip.To numerically verify the experimental findings,a time-dependent coupled-wave equation model was developed,which described the physics processes inside the gain and SA regions.The numerical results agree well with the experimental measurements.We further experimentally demonstrated that the weighted sum output can readily be encoded into the self-pulsation frequency of the DFB-SA neuron.We also benchmarked the handwritten digit classification task with a simple single-layer fully connected neural network.By using the experimentally measured dependence of the self-pulsation frequency on the bias current in the gain region as an activation function,we can achieve a recognition accuracy of 92.2%,which bridges the gap between the continuous valued artificial neural networks and spike-based neuromorphic networks.To the best of our knowledge,this is the first experimental demonstration of a photonic integrated spiking neuron based on a DFB-SA,which shows great potential to realizing large-scale multiwavelength photonic spiking neural network chips. | YUECHUN SHI SHUIYING XIANG XINGXING GUO YAHUI ZHANG HONGJI WANG DIANZHUANG ZHENG YUNA ZHANG YANAN HAN YONG ZHAO XIAOJUN ZHU XIANGFEI CHEN XUN LI YUE HAO | 2023 | Photonics Research2023，11，8： | 2 |
| 17 | High-Throughput Rice Density Estimation from Transplantation to Tillering Stages Using Deep Networks显示文摘Rice density is closely related to yield estimation,growth diagnosis,cultivated area statistics,and management and damage evaluation.Currently,rice density estimation heavily relies on manual sampling and counting,which is inefficient and inaccurate.With the prevalence of digital imagery,computer vision(CV)technology emerges as a promising alternative to automate this task.However,challenges of an in-field environment,such as illumination,scale,and appearance variations,render gaps for deploying CV methods.To fill these gaps towards accurate rice density estimation,we propose a deep learningbased approach called the Scale-Fusion Counting Classification Network(SFC^(2)Net)that integrates several state-of-the-art computer vision ideas.In particular,SFC^(2)Net addresses appearance and illumination changes by employing a multicolumn pretrained network and multilayer feature fusion to enhance feature representation.To ameliorate sample imbalance engendered by scale,SFC^(2)Net follows a recent blockwise classification idea.We validate SFC^(2)Net on a new rice plant counting(RPC)dataset collected from two field sites in China from 2010 to 2013.Experimental results show that SFC^(2)Net achieves highly accurate counting performance on the RPC dataset with a mean absolute error(MAE)of 25.51,a root mean square error(MSE)of 38.06,a relative MAE of 3.82%,and a R^(2) of 0.98,which exhibits a relative improvement of 48.2%w.r.t.MAE over the conventional counting approach CSRNet.Further,SFC^(2)Net provides high-throughput processing capability,with 16.7 frames per second on 1024×1024 images.Our results suggest that manual rice counting can be safely replaced by SFC^(2)Net at early growth stages.Code and models are available online at http://gffzzb7e65fbbf9234179skw9vvpfpbcqb6uxo.ffgz.tsg.suse.edu.cn/sfc2net. | Liang Liu Hao Lu Yanan Li Zhiguo Cao | 2020 | Plant Phenomics2020，2，1： | 2 |
| 18 | The main restorer Rf3 of maize S type cytoplasmic male sterility encodes a PPR protein that functions in reduction of the transcripts of orf355显示文摘Dear Editor,Male sterile lines,especially cytoplasmic male sterile(CMS)lines,are extensively used in commercial hybrid seed production.Therefore a better understanding of the genetic basis of fertility restoration for CMS is important for the utility of heterosis in crops.In general,restorer of fertility(Rf)is controlled by one or two major genomic genes,and most of the Rf genes encode pro-teins containing P type pentatricopeptide repeat(PPR)motifs(Wang et al.,2006;Hu et al.,2012;Tang et al.,2014;Liu et al.,2016).S type CMS(CMS-S)is the main type of maize CMS with wide cytoplasmic sources,and orf355-orf77 in CMS-S was associated with male sterility(Zabala et al.,1997).The 5'stem-loop of the transcript of orf355-orf77 was thought to be associ-ated with its stability(Xiao et al.,2006).Recently,Xiao et al.(2020)confirmed that orf355 is the causal gene of CMS-S.Rf3,the main restorer of CMS-S,has been mapped to the long arm of chromosome 2 for a long time(Laughnan and Gabay,1978).Since then,great efforts have been made on genetic mapping and cloning of this gene(Xu et al.,2009). | Xiner Qin Shike Tian Wenliang Zhang Qi Zheng Hao Wang Yang Feng Yanan Lin Jihua Tang Yi Wang Jianbing Yan Mingqiu Dai Yonglian Zheng Bing Yue | 2021 | Molecular Plant2021，14，12： | 2 |
| 19 | Purple-bluish tongue is associated with platelet counts, and the recurrence of epithelial ovarian cancer显示文摘ObjectiveTo 评估在紫色带蓝色的舌头和血小板计数之间的关系,并且推进与 82 个上皮的卵巢的癌症病人全部的上皮的卵巢的 cancer.MethodsA 的复发检验他们的协会在这研究被注册。簇分析被用于组织 patients’P 红绿蓝 (Red-R;Green-G;Blue-B;红绿蓝的平均百分比, P 红绿蓝 ) 价值。接收装置操作特征(巨鸟) 曲线为检测紫色带蓝色的舌头的诊断标准被执行。2 测试被用来估计在紫色带蓝色的舌头和血小板之间的关系上皮的卵巢的癌症的计数,和复发。perioperative (外科手术前) 血小板水平是 examinedwith 舌头图象,疾病 recurrence.ResultsTongue 图象被分类进基于 P 由簇分析的图象的红绿蓝 价值。在簇 “1” 的盒子的数字(正常颜色舌头) 是 16 并且聚类 “2”(紫色带蓝色的舌头) 是 66。二组 P 红绿蓝 价值,由簇分析分类,显著地与基于视觉的舌头颜色识别被相关(Kappa = 0.852, P < 0.001 ) 。巨鸟曲线证明 P b 到 P r 有最高诊断的价值。敏感和 P b 到 P r 分别地是 95.3% 和 88.9% ,最佳的截止的点是 0.71。紫色带蓝色的舌头显著地与增加的血小板计数被相关(P < 0.001 ) 。两个都,增加的血小板数( P = 0.01 )并且紫色带蓝色的舌头与上皮的卵巢的癌症的复发被联系( P < 0.001 ) P b 到 P 当为紫色带蓝色的舌头诊断的指示物在症状模式使用了,比 0.71 大的 r 能服务在繁体中文药的鉴定。紫色带蓝色的舌头,与增加的血小板计数联系了,密切也与上皮的卵巢的癌症的复发被相关。 | Hao Jian Zhu Cuihong Cao Rui Yang Xue Ding Xiuli Man Yanan Wu Xiongzhi | 2016 | Journal of Traditional Chinese Medicine2016，36，3： | 2 |
| 20 | Pattern recognition in multi-synaptic photonic spiking neural networks based on a DFB-SA chip显示文摘Spiking neural networks(SNNs)utilize brain-like spatiotemporal spike encoding for simulating brain functions.Photonic SNN offers an ultrahigh speed and power efficiency platform for implementing high-performance neuromorphic computing.Here,we proposed a multi-synaptic photonic SNN,combining the modified remote supervised learning with delayweight co-training to achieve pattern classification.The impact of multi-synaptic connections and the robustness of the network were investigated through numerical simulations.In addition,the collaborative computing of algorithm and hardware was demonstrated based on a fabricated integrated distributed feedback laser with a saturable absorber(DFB-SA),where 10 different noisy digital patterns were successfully classified.A functional photonic SNN that far exceeds the scale limit of hardware integration was achieved based on time-division multiplexing,demonstrating the capability of hardware-algorithm co-computation. | Yanan Han Shuiying Xiang Ziwei Song Shuang Gao Xingxing Guo Yahui Zhang Yuechun Shi Xiangfei Chen Yue Hao | 2023 | Opto-Electronic Science2023，2，9： | 1 |
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