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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Characterization and fine mapping of an early senescence mutant (es-t) in Oryza sativa L.显示文摘An es-t (early senescence-temporary) mutant, produced by ethylene methylsulfonate treatment of strain Nipponbare, was identified in rice. The leaves of es-t appeared yellow at the seedling stage, and had decreased chlorophyll content. Rust spots were found during growth in es-t, especially at the leaf margin and tip. The plants showed a typical early-senescence phenotype at the milky stage. The leaf surface of es-t appeared smoother than wild-type leaves under a scanning electron microscope, because the leaves lack siliceous protuberances around the stoma. Chloroplasts grow abnormally and are filled with many starch grains in es-t. Paraffin section analysis showed that the development of the sclerenchyma cells and vascular bundles were also abnormal in es-t. Genetic analysis indicated that es-t was controlled by a recessive gene, which was finely mapped to a 42-kb interval on chromosome 5. These results will facilitate the positional cloning and functional studies of the gene. | YANG YaoLong RAO YuChun LIU HuiJuan FANG YunXia DONG GuoJun HUANG LiChao LENG YuJia GUO LonBiao ZHANG GuangHeng HU Jiang GAO ZhenYu QIAN Qian ZENG DaLi | 2011 | Chinese Science Bulletin2011，56，23： | 8 |
| 3 | The Trace Elements are Bounded by Organic Functional Groups in Coal:A Studying Result Based on FTIR Analysis显示文摘The relationship between trace elements in coal and organic functional groups of coal,also some of aromatic structure,was investigated by using curve fitting of infrared spectra.Cluster analysis was also performed according to the degree of affinity of organic groups to the trace elements.The results show that there is a possibility that trace elements,especially LREE,were bound to peripheral organic functional groups of middle rank coal macromolecule.The most possible functional group that binds trace element is the hydroxyl,and to the less degree,the asymmetric-CH_3and>CH_2 stretching,-CH_3 stretching,etc.The degree of affinity of trace elements to different functional groups varies.The tendency obeys the natural structural changing law of trace elements—the periodic law.The deviation of some trace elements from this regular trend is attributed to the deviation of intrinsic'confusion degree'(conventional molar entropy)of the matter system of coal basin,which is affected by the inner and outer factors during the evolution. | YANG Jianye WANG Guangheng ZHANG Weiguo | 2016 | Acta Geologica Sinica(English Edition)2016，90，1： | 5 |
| 4 | Genome-wide association study and transcriptome analysis reveal new QTL and candidate genes for nitrogen-deficiency tolerance in rice显示文摘The development of rice cultivars with improved nitrogen use efficiency(NUE)is desirable for sustainable agriculture.Achieving this goal depends in part on understanding how rice responds to low soil nitrogen(N)and identifying causative genes underlying this trait.To identify quantitative trait loci(QTL)or genes associated with low N response,we conducted a genome-wide association study(GWAS)using a diverse panel of 230 rice accessions and performed a transcriptomic investigation of rice accessions with differential responses to low N stress at two N levels.We detected 411 GWAS-associated genes in 5 QTL and 2722 differentially expressed genes in response to low N,of which 24 were identified by both methods and ranked according to gene annotations,literature queries,gene expression,and genetic diversity analysis.The large-scale datasets obtained from this study reveal low N-responsive characteristics and provide insights towards understanding the regulatory mechanisms of N-deficiency tolerance in rice,and the candidate genes or QTL would be valuable resources for increasing rice NUE via molecular biotechnology. | Qing Li Xueli Lu Changjian Wang Lan Shen Liping Dai Jinli He Long Yang Peiyuan Li Yifeng Hong Qiang Zhang Guojun Dong Jiang Hu Guangheng Zhang Deyong Ren Zhenyu Gao Longbiao Guo Qian Qian Li Zhu Dali Zeng | 2022 | The Crop Journal2022，10，4： | 3 |
| 5 | Influence of Heat Treatment on Microstructure and Mechanical Properties of Plasma Sprayed FeCrMoCBY Amorphous Coatings显示文摘The changes of the microstructure and the mechanical properties of FeCrMoCBY amorphous coatings prepared by plasma spraying after heat treatment were investigated.300,400,500 and 600℃were selected as the heat treatment temperature,and the crystallization phenomenon occurred after the heat treatment at 600℃.The crystallization products of the coating heat-treated at 600℃were a-Fe and Fe23(C,B)6.Heat treatment was beneficial to the microhardness and the bonding strength of the coatings.The microhardness of the coating heat-treated at 600℃increased obviously,and the strongest bonding strength occurred in the coating heat-treated at 500℃.The improvement of the wear resistance of the coatings could attribute to heat treatment as well,and the wear resistance of the coating heat-treated at 600℃was the optimum,compared with the coating heat-treated at 500℃. | 吴林涛 周泽华 DEND Yong ZHANG Xin WANG Miqi WANG Zehua ZHANG Kaicheng YANG Guangheng | 2021 | Journal of Wuhan University of Technology(Materials Science)2021，36，5： | 1 |
| 6 | Under-standing the hydrological trends of river basins in China 显示文摘 | Zhentao Cong Jingjing Zhao Dawen Yang Guangheng Ni | 2010 | Journal of Hydrology2010，388，： | 1 |
| 7 | Protection Performance of Plasma Sprayed Al_(2)O_(3)-13 wt%TiO_(2) Coating Sealed with an Organic-inorganic Hybrid Agent显示文摘An organic-inorganic hybrid sealing agent was fabricated and used in the plasma sprayed Al_(2)O_(3)-13 wt%TiO_(2)coating,and conventional silicone agent was also used for comparison.Protection performance of the coatings was comprehensively evaluated based on both anti-corrosion and anti-biofouling properties.The results reveal that the sealing treatment is remarkably useful to decrease the porosity of the coating,and the porosity of the coating sealed with the hybrid agent is only 0.035%.Immersion corrosion test and Tafel polarization test reveal that the sealed coating with the hybrid agent exhibits a better corrosion resistance by compared with the coating sealed with silicone agent.The corrosion current density i_(corr) of the hybrid agent sealed coating is only 0.7×10^(-6)A·cm^(-2).Moreover,anti-biofouling tests both in the outdoor analogue hydraulic environment and in the natural marine environment prove that the mentioned novel coating presents a better combination of corrosion resistance and anti-biofouling property by compared with the other coatings,and it could be used as a protection of metal components in the marine environment. | 张凯城 周泽华 DENG Yong WANG Guangyu WANG Zehua WU Lintao YANG Guangheng | 2022 | Journal of Wuhan University of Technology(Materials Science)2022，37，3： | 1 |
| 8 | Martingale Musielak-Orlicz Hardy spaces显示文摘In this article,we introduce the martingale Musielak-Orlicz Hardy spaces H_φ^*(■),Pφ(?),H_φ^S(■),Qφ(?)and H_φ^s(■),respectively,via the maximal function,the quadratic variation and the conditional quadratic variation of martingales.We then establish the atomic characterizations of H_φ^s(■),Pφ(■)and Qφ(■).As applications,we obtain the dual space of H_φ^s(■)and several martingale inequalities which further clarify the relations among H_φ^*(■),Pφ(■),H_φ^S(■),Qφ(■)and H_φ^s(■).Especially,as special cases,the results on atomic characterizations of H_φ^s(■),Pφ(?)and Qφ(■)as well as on the dual space of H_φ^s(■)in the weighted case are also new. | Guangheng Xie Yong Jiao Dachun Yang | 2019 | Science China Mathematics2019，62，8： | 1 |
| 9 | Photosynthesis Characteristics of Three Species of Forages in the Arid-Hot Valleys显示文摘By using TPS-1 portable photosynthesis measuring system, the photosynthesis characteristics of three kinds of high quality forages used in the arid-hot valley eco-agricultural models in Yuanmou were measured. The paper shows that Pennisetum purpureum Schumach is the heliophilous shade tolerance C4 plant and Styiosanthes guianensis is the heliophilous shade tolerance plant, both of them could make full use of the light energy under the weak light environment and have relatively strong CO2 assimilation capacity.Cajanus cajan(L.) Millspaugh is the strong heliophilous plant with high requirement for light and has a rela-tively weak CO2 assimilation capacity. Generally, these three kinds of high quality forages are drought resistant and show a relatively good adaptability to the arid-hot valley environment.To improve cultivation administration level and to interplant timely in the forest can be helpful to the ecological niche and to improve the productivity force. | YANG Yanxian LIAO Chengfei SHA Yucang PAN Zhixian FENG Guangheng JI Zhonghua | 2008 | Wuhan University Journal of Natural Sciences2008，13，3： | 0 |
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