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| 1 | Mitochondrial transcription termination factor 2 binds to entire mitochondrial DNA and negatively regulates mitochondrial gene expression显示文摘(mTERF2 ) Mitochondrial 抄写结束因素 2 是绑在 mitochondrial DNA 的 mitochondrial 矩阵蛋白质。以前的研究证明了 mTERF2 的 overexpression 能禁止房间增长,但是机制到目前为止一直不是明确的。这研究试图在 vivo 介绍 mTERF2 的有约束力的模式给 mitochondrial DNA (mtDNA ) ,并且在 mtDNA, mRNA 抄写,和蛋白质翻译的复制上调查了 mTERF2 的生物功能。到全部 mtDNA 的 mTERF2 绑定经由染色质 immunoprecipitation 分析被识别。当 mTERF2 是在 HeLa 房间的 overexpressed 时,线粒体基因的 mtDNA 复制效率和表示层次显著地被禁止。mtDNA 内容的抑制水平是有 mRNA 和 mitochondrial 蛋白质表示的减少的层次的一样。总的来说, mTERF2 可能基于它 mtDNA 复制上的否定效果是一个细胞生长禁止者,它最后下面调整在是必要的为的线粒体的氧化 phosphorylation 部件,细胞是的所有精力新陈代谢。 | Weiwei Huang Min Yu Yang Jiao Jie Ma Mingxing Ma Zehua Wang Hong Wu Deyong Tan | 2011 | Acta Biochimica et Biophysica Sinica2011，43，6： | 17 |
| 2 | MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1显示文摘MicroRNAs (miRNAs ) 由抑制最近在 carcinogenesis 和转移在我们 non-protein-coding RNA 的角色的理解带给卓见的 posttranscriptional 施加功能。在这研究,我们在 CRC 在 colorectal 癌症(CRC ) 和它的潜在的临床的应用程序描述了函数和 miR-139-5p 的分子的机制。我们发现 miR-139-5p 是显著地, CRC 与邻近的 noncancerous 纸巾(NCT ) 相比取样的在 73.8% 的 downregulated,和减少的 miR-139-5p 与穷人被联系预后。功能的分析证明 miR-139-5p 的那个宫外的表达式在 vivo 在 vitro 和转移压制了 CRC 房间移植和侵略。机械学的调查表明 miR-139-5p 由指向 AMFR 和 NOTCH1 压制 CRC 房间侵略和转移。二基因 phenocopied 击倒 CRC 上的 miR-139-5p 的禁止的效果转移。而且,二基因的蛋白质层次与 NCT 相比是在 CRC 样品的 upregulated,并且相反地与 miR-139-5p 表示相关。增加的 NOTCH1 蛋白质表示与 CRC 病人的差的预后被相关。一起,我们的数据显示 miR-139-5p 为 CRC 是潜在的肿瘤 suppressor 和预示的因素,并且指向 miR-139-5p 可以镇压 CRC 的转移并且改善幸存。 | Mingxu Song Yuan Yin Jiwei Zhang Binbin Zhang Zehua Bian Chao Quan Leyuan Zhou Yaling Hu Qifeng Wang Shujuan Ni Bojian Fei Weili Wang Xiang Du Dong Hua Zhaohui Huang | 2014 | Protein & Cell2014，5，11： | 14 |
| 3 | SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer显示文摘SIRT7,a sirtuin family member implicated in aging and disease,is a regulator of metabolism and stress responses.It remains elusive how human somatic stem cell populations might be impacted by SIRT7.Here,we found that SIRT7 expression declines during human mesenchymal stem cell(hMSC)aging and that SIRT7 deficiency accelerates senescence.Mechanistically,SIRT7 forms a complex with nuclear lamina proteins and heterochromatin proteins,thus maintaining the repressive state of heterochromatin at nuclear periphery.Accordingly,deficiency of SIRT7 results in loss of heterochromatin,derepression of the LINE1 retrotransposon(LINE1),and activation of innate immune signaling via the cGAS-STING pathway.These agingassociated cellular defects were reversed by overexpression of heterochromatin proteins or treatment with a LINE1 targeted reverse-transcriptase inhibitor.Together,these findings highlight how SIRT7 safeguards chromatin architecture to control innate immune regulation and ensure geroprotection during stem cell aging. | Shijia Bi Zunpeng Liu Zeming Wu Zehua Wang Xiaoqian Liu Si Wang Jie Ren Yan Yao Weiqi Zhang Moshi Song Guang-Hui Liu Jing Qu | 2020 | Protein & Cell2020，11，7： | 10 |
| 4 | Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration显示文摘Accumulating evidence indicates an association between the circadian clock and the aging process.However,it remains elusive whether the deregulation of circadian clock proteins underlies stem cell aging and whether they are targetable for the alleviation of aging-associated syndromes.Here,we identified a transcription factor-independent role of CLOCK,a core component of the molecular circadian clock machinery,in counteracting human mesenchymal stem cell(hMSC)decay.CLOCK expression was decreased during hMSC aging.In addition,CLOCK deficiency accelerated hMSC senescence,whereas the overexpression of CLOCK,even as a transcriptionally inactive form,rejuvenated physiologically and pathologically aged hMSCs.Mechanistic studies revealed that CLOCK formed complexes with nuclear lamina proteins and KAP1,thus maintaining heterochromatin architecture and stabilizing repetitive genomic sequences.Finally,gene therapy with lentiviral vectors encoding CLOCK promoted cartilage regeneration and attenuated age-related articular degeneration in mice.These findings demonstrate a noncanonical role of CLOCK in stabilizing heterochromatin,promoting tissue regeneration,and mitigating aging-associated chronic diseases. | Chuqian Liang Zunpeng Liu Moshi Song Wei Li Zeming Wu Zehua Wang Qiaoran Wang Si Wang Kaowen Yan Liang Sun Tomoaki Hishida Yanning Cai Juan Carlos lzpisua Belmonte Pedro Guillen Piu Chan Qi Zhou Weiqi Zhang Jing Qu Guang-Hui Liu | 2021 | Cell Research2021，31，2： | 8 |
| 5 | Satellite-observed trends in the Arctic sea ice concentration for the period 1979–2016显示文摘Arctic sea ice cover has decreased dramatically over the last three decades. This study quanti?es the sea ice concentration(SIC) trends in the Arctic Ocean over the period of 1979–2016 and analyzes their spatial and temporal variations. During each month the SIC trends are negative over the Arctic Ocean, wherein the largest(smallest) rate of decline found in September(March) is-0.48%/a(-0.10%/a).The summer(-0.42%/a) and autumn(-0.31%/a) seasons show faster decrease rates than those of winter(-0.12%/a) and spring(-0.20%/a) seasons. Regional variability is large in the annual SIC trend. The largest SIC trends are observed for the Kara(-0.60%/a) and Barents Seas(-0.54%/a), followed by the Chukchi Sea(-0.48%/a), East Siberian Sea(-0.43%/a), Laptev Sea(-0.38%/a), and Beaufort Sea(-0.36%/a). The annual SIC trend for the whole Arctic Ocean is-0.26%/a over the same period. Furthermore, the in?uences and feedbacks between the SIC and three climate indexes and three climatic parameters, including the Arctic Oscillation(AO), North Atlantic Oscillation(NAO), Dipole anomaly(DA), sea surface temperature(SST), surface air temperature(SAT), and surface wind(SW), are investigated. Statistically, sea ice provides memory for the Arctic climate system so that changes in SIC driven by the climate indices(AO, NAO and DA) can be felt during the ensuing seasons. Positive SST trends can cause greater SIC reductions, which is observed in the Greenland and Barents Seas during the autumn and winter. In contrast, the removal of sea ice(i.e., loss of the insulating layer) likely contributes to a colder sea surface(i.e., decreased SST), as is observed in northern Barents Sea. Decreasing SIC trends can lead to an in-phase enhancement of SAT, while SAT variations seem to have a lagged in?uence on SIC trends. SW plays an important role in the modulating SIC trends in two ways: by transporting moist and warm air that melts sea ice in peripheral seas(typically evident inthe Barents Sea) and by exporting sea ice out of the Arctic Ocean via passages into the Greenland and Barents Seas, including the Fram Strait, the passage between Svalbard and Franz Josef Land(S-FJL),and the passage between Franz Josef Land and Severnaya Zemlya(FJL-SZ). | WANG Yunhe BI Haibo HUANG Haijun LIU Yanxia LIU Yilin LIANG Xi FU Min ZHANG Zehua | 2019 | Journal of Oceanology and Limnology2019，37，1： | 7 |
| 6 | Vertically stacked holey graphene/polyaniline heterostructures with enhanced energy storage for on-chip micro-supercapacitors显示文摘平面 micro-supercapacitors (MSC ) 为 microelectronic 设备由于他们的唯一的结构的设计和尺寸相容性画了广泛的研究注意。Graphene 广泛地被用来改进 microscale 的表演电气化学的电容器。然而,为基于 graphene 的 microscale 设备的内在的电气化学的机制的调查仍然不是足够的。这里,有各种各样的典型体系结构的 micro-supercapacitors 作为模型被制作学习 graphene 效果,和他们的电气化学的表演也被评估。结果证明离子的可接近性和吸附极大地在有穴的 graphene 中介层的介绍以后被改进。这研究提供一条新线路理解内在的电气化学的行为并且为高度有效的在薄片上拥有令人激动的潜力微精力的存储。 | Xiaocong Tian Bei Xiao Xu Xu Lin Xu Zehua Liu Zhaoyang Wang Mengyu Yan Qiulong Wei Liqiang Mai | 2016 | Nano Research2016，9，4： | 7 |
| 7 | Characteristics of Fe-based WC Composite Coatings Prepared by Double-pass Plasma Cladding Process显示文摘The Fe-based WC composite coatings were clad on Q235 steel by double-pass plasma cladding method,in which the WC-Co(WC covered with cobalt:78wt%WC,12wt%Co)doping was about 10wt%,20wt%and 40wt%,respectively.The microstructure and wear performance of the composite coatings were investigated by X-ray diffraction(XRD),scanning electron microscope(SEM),energy dispersive spectrometer(EDS)and ball-disc wear tests.The results show that the clad coatings contain mainly?-Fe,WC and carbides(Cr23C6,Fe3W3C-Fe4W2C)phases and the precipitation of carbides increases with the increase of WC-Co doping content.The WC-Co doping content has an obvious effect on the microstructure of the clad coatings.For the clad coatings with low WC-Co doping,the microstructure gradually transforms from planar crystal at the interface of substrate/coating to cell/dendritic crystal at the middle and the upper portion of the coatings.But there are a number of fishbone-like structure at the middle and the upper portion of clad coating with 40wt%WC-Co doping.The microstructure at the top is smaller than that at the bottom for all the coatings.The maximum of hardness of the clad coatings is 72.3HRC which is about 6.9 as much as the hardness of Q235 steel substrate.The composite coatings have good wear resistance due to the reinforcement of carbide particles and the strong bonding between carbide particles and ferroalloy.The suitable increase of WC-Co doping content can improve the wear resistance of the composite coatings. | Jiang Shaoqun Ren Qingwen Ying, Ding Gang, Wang Yu, Yi Wang Zehua Zhou Zehua | 2012 | 稀有金属材料与工程2012，41，S1： | 6 |
| 8 | CC chemokine receptor 7 promotes triple-negative breast cancer growth and metastasis显示文摘 | Jiao Wu Lu Li Jianing Liu Yang Wang Zehua Wang Yangdan Wang Wenjing Liu Zhongmei Zhou Ceshi Chen Rong Liu Runxiang Yang | 2018 | Acta Biochimica et Biophysica Sinica2018，50，9： | 5 |
| 9 | Black phosphorus inverter devices enabled by in-situ aluminum surface modification显示文摘Two-dimensional black phosphorus (BP) generally exhibits a hole-dominated transport characteristic when configured as field-effect transistor devices. The effective control of charge carrier type and concentration is very crucial for the application of BP in complementary electronics. Herein, we report a facile and effective electron doping methodology on BP, through in situ surface modification with aluminum (Al). The electron mobility of few-layer BP is found to be largely enhanced to ~ 10.6 cm^2·V^–1·s^–1 by over 6 times after aluminum modification. In situ photoelectron spectroscopy characterization reveals the formation of Al–P covalent bond at the interface, which can also serve as local gate to tune the transport properties in BP layers. Finally, a spatially-controlled aluminum doping technique is employed to establish a p–n homojunction on a single BP flake, and hence to realize the complementary inverter devices, where the highest gain value of ~ 33 is obtained. | Yue Zheng Zehua Hu Cheng Han Rui Guo Du Xiang Bo Lei Yanan Wang Jun He Min Lai Wei Chen | 2019 | Nano Research2019，12，3： | 5 |
| 10 | Mechanical stress distribution and risk assessment of 110 kV GIS insulator considering Al_(2)O_(3)settlement显示文摘The growing application of gas insulated switchgear(GIS)in electric power system asks for higher reliability of epoxy(EP)insulators,thus it is important to seek effective methods to improve the operating reliability of GIS insulators.On the basis of the 110 kV GIS insulator,this study studied the aluminium oxide(Al_(2)O_(3))settlement in the curing process and the stress distribution of the horizontally laid GIS.Besides,the risk coefficient was defined to evaluate the operating reliability of insulators laid by different methods(I-V).Some conclusions are shown below:the Al_(2)O_(3)settlement in the curing process causes the insulator density to have a large variation from 2.13 to 2.32 g/cm^(3).The Al_(2)O_(3)content has a great influence on the mechanical performances of EP/Al_(2)O_(3)system.The first principle stress is localised on the upper interface between the insulator and the conductor,which is the main threat to the mechanical damage of insulator.The laying method V appears to be optimal with a pretty low risk coefficient of 31.5.In actual application,for the horizontally laid GIS,the insulator should be laid with the mould gate downward to improve its mechanical reliability. | Hucheng Liang Boxue Du Jin Li Zehua Wang | 2019 | High Voltage2019，4，1： | 5 |
| 11 | Design and test of soft-pot-tray automatic embedding system for light-economical pot seedling nursery machine显示文摘Most of the commercially-available pot seedling nursery machines are incompatible with soft-pot-trays and are labor-intensive and low in productivity.A soft-pot-tray automatic embedding system was developed in this study to achieve automatic embedding of the soft pot tray into the hard tray following sowing and covering with soil.A control system was constructed using the Arduino program development environment.An embedded-hard-tray automatic lowering mechanism and conveyor-belt-based pot-tray embedding system were designed.Dynamics analysis was conducted to derive an equation to describe the embedding process of the soft pot tray into the embedded hard tray.A prototype of the soft-pot-tray automatic embedding system was manufactured and tested.The analytical equation suggested that a minimum linear velocity of 0.86 m/s was required for a complete embedding process.The experimental results showed that the embedded-hard-tray automatic lowering mechanism was reliable and stable as the tray placement success rate was greater than 99%.The successful tray embedding rate was 100%and the seed exposure rate was less than 1%with a linear velocity of the conveyor belt of 0.92 m/s.The experiment findings agreed well with the analytical results.The proposed soft-pot-tray automatic embedding system satisfied the technical specifications for a light-economical pot seedling nursery machine. | Lintao Chen Xu Ma Cong Wang Hongwei Li Zehua Li Xueshen Chen Tao Chen | 2020 | International Journal of Agricultural and Biological Engineering2020，13，1： | 4 |
| 12 | The strain seismograms of P- and S-waves of a local event recorded by four-gauge borehole strainmeter显示文摘At a sampling rate of 100 samples per second,the YRY-4 four-gauge borehole strainmeters(FGBS) are capable of recording transient strains caused by seismic waves such as P and S waves or strain seismograms. At such a high sampling rate, data from the YRY-4 strainmeters demonstrate fairly satisfactory self-consistency. The strain tensor seismograms demonstrate the senses of motion of P waves, that is, the type of seismic wave travels in the direction of the maximum normal strain change. The observed strain patterns of S waves significantly differ from those of P waves and should contain information about the source mechanism. Spectrum analysis shows that the strain seismograms are consistent with conventional broadband seismograms from the same site. | Zehua Qiu Shunliang Chi Zhenming Wang Seth Carpenter Lei Tang Yanping Guo Guang Yang | 2015 | Earthquake Science2015，28，3： | 4 |
| 13 | Effect of shrinkage porosity on mechanical properties of ferritic ductile iron显示文摘Casting defects could largely affect the mechanical properties of casting products. A number of test pieces made of ductile iron (EN-GJS-400-18-LT) with different levels of shrinkage porosity were prepared and then tensile and fatigue tests were performed to investigate the impact of shrinkage porosity on their mechanical properties. The results showed that the tensile strength decreases linearly with increasing of the shrinkage porosity. The tensile elongation decreases sharply with the increase of the shrinkage porosity mainly due to the non-uniform plastic deformation. The fatigue life also dramatically declines with increasing of the porosity and follows a power law relationship with the area percentage of porosity. The existence of the shrinkage porosity made the fatigue fracture complex. The shrinkage pores, especially those close to the surface usually became the crack initiation sites. For test pieces with less porosity, the fatigue fracture was clearly composed of crack initiation, propagation, and overloading. While for samples with high level of porosity, multiple crack initiation sites were observed. | Wang Zehua Zhao Weihua Zhou Zehua Jiang Shaoqun Yu Xuru Wang Qiuxin | 2013 | China Foundry2013，10，3： | 3 |
| 14 | Self-propagating High-temperature Synthesis of Al_2O_3-TiB_2 Coatings by Aluminothermic Reactions显示文摘The Al2O3-TiB2 coatings were fabricated on Q235 steel by self-propagating high-temperature synthesis(SHS)process using aluminothermic reactions with aluminum,titania,boron oxide and ferric oxide powders.The effect of the content of excessive aluminum in the reactants on Al2O3-TiB2 coatings was studied when only Al-TiO2-B2O3 system was used for preparation of the coatings.The results indicate that the combustion reaction cannot occur when excessive aluminum is over 40wt%and the coating has good quality when excessive aluminum is 20wt%.In order to improve the bonding of the coating and substrate and optimize the ratio of Al2O3/TiB2,composite reaction systems Al-TiO2-B2O3 and Al-Fe2O3 were used for the preparation of Al2O3-TiB2 coatings.The XRD result shows that the coatings contain FeAl intermetallic compound which can improve efficiently the interface bonding of the coating and substrate.The percentage of Al-Fe2O3 system in reactants has only a small effect on the hardness of Al2O3-TiB2 coating,which is about 22000 MPa(Hv),but has an obvious effect on the morphology and interface bonding of the coatings. | Wang Gang,Jiang Shaoqun,Wang Zehua,Cai Dong,Yi Yu,Zhou Zehua Hohai University,Nanjing 210098,China$$$$ | 2012 | 稀有金属材料与工程2012，41，S1： | 3 |
| 15 | In-situ observation of electrical tree evolution in epoxy dielectrics with internal cracks显示文摘Gas-filled internal crack might appear in thermoset materials like epoxy resin during the equipment manufacturing,which would become a vulnerable local region to initiate the electrical tree,thus prone to cause insulation failure.The withstand voltage test was carried on epoxy samples with artificial cracks based on a rod-plane electrode arrange-ment.Simultaneously,surface state variation and tree evolution with crack were observed by an optical microscope in conjunction with a charge-coupled device camera.The changes in morphology and chemical status of the crack surface were characterized by scanning electron microscopy,laser Raman spectrometer and energy dispersive spec-trometer,respectively.It was found that the erosion and tree started from the borderline of crack under a relatively low electric field strength;however,the area near the electrode had relatively little damage.The breaking of epoxy molecular chains coarsens the crack surface and further forms deep channels on a micro-level,which is the forerunner of the electrical tree inception.Based on these,the initiation mechanisms of the crack-induced electrical tree and the reasons for the erosion near the borderline have been revealed.This study provides a train thought for the polymer degradation opening up into the initial tree channel during tree evolution processes. | Zehua Wu Huidong Tian Sijia Zhu He Li Qingyu Wang Zongliang Xie Peng Liu Zongren Peng | 2021 | High Voltage2021，6，2： | 3 |
| 16 | IL1RN promotes osteoblastic differentiation via interacting with ITGB3 in osteoporosis显示文摘The occurrence and progress of osteoporosis(OP)are partially caused by impaired osteoblast differentiation.Interleukin-I receptor antagonist(IL1RN)is an immune modulatory molecule that commonly functions by means of competing the binding site of IL-1R with IL-1.Although it was recently reported that IL1RN is involved in osteoblast differentiation,the role of IL1RN in osteogenesis remains unclear.In this work,we first investigated the expression pattern of IL1RN in ovariectomy mice and in vitro osteogenic induction of MC3T3-E1 and C3H10T1/2 cells.To verify the exact role of IL1RN in osteoblast differentiation,we established IL1RN-downregulated/upregulated cell lines.The results indicated that IL1RN was constantly expressed in MC3T3-E1 and C3H10T1/2 cells.Interestingly,an increase of IL1RN expression in osteoblasts occurred when osteoblasts were cultured in osteogenic medium(OM).As expected,silencing of IL1RN attenuated the osteogenic effect of OM,while IL1RN overexpression increased the osteogenic staining and promoted the expression of osteogenic markers,including alkaline phosphatase,osterix,and osteocalcin.In addition to evaluating the function of IL1RN in osteoblasts,we also investigated the molecular mechanism of the role of IL1RN in osteoblasts.We found that IL1RN interacts with integrinβ3 to activateβ-catenin signaling,which finally regulates osteoblast differentiation.Taken together,this study provides the framework that IL1RN,as a novel regulator of osteogenesis,may be a potential therapeutic target for the treatment of OP. | Zehua Zou Ruixuan Liu Yiwen Wang Yufei Xing Zuowei Shi Kaifu Wang Daming Dong | 2021 | Acta Biochimica et Biophysica Sinica2021，53，3： | 3 |
| 17 | Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes显示文摘HBV is considered as a“stealth”virus that does not invoke interferon(IFN)responses;however,the mechanisms by which HBV bypasses innate immune recognition are poorly understood.In this study,we identified adenosine deaminases acting on RNA 1(ADAR1),which is a key factor in HBV evasion from IFN responses in hepatocytes.Mechanically,ADAR1 interacted with HBV RNAs and deaminated adenosine(A)to generate inosine(I),which disrupted host immune recognition and thus promoted HBV replication.Loss of ADAR1 or its deficient deaminase activity promoted IFN responses and inhibited HBV replication in hepatocytes,and blocking the IFN signaling pathways released the inhibition of HBV replication caused by ADAR1 deficiency.Notably,the HBV X protein(HBx)transcriptionally promoted ADAR1 expression to increase the threshold required to trigger intrinsic immune activation,which in turn enhanced HBV escape from immune recognition,leading to persistent infection.Supplementation with 8-azaadenosine,an ADAR1 inhibitor,efficiently enhanced liver immune activation to promote HBV clearance in vivo and in vitro.Taken together,our results delineate a molecular mechanism by which HBx promotes ADAR1-derived HBV immune escape and suggest a targeted therapeutic intervention for HBV infection. | Liyuan Wang Yang Sun Xiaojia Song Zehua Wang Yankun Zhang Ying Zhao Xueqi Peng Xiaodong Zhang Chunyang Li Chengjiang Gao Nailin Li Lifen Gao Xiaohong Liang Zhuanchang Wu Chunhong Ma | 2021 | Cellular & Molecular Immunology2021，18，8： | 2 |
| 18 | Arctic multiyear sea ice variability observed from satellites:a review显示文摘In comparison with seasonal sea ice(first-year ice,FY ice),multiyear(MY)sea ice is thicker and has more opportunity to survive through the summer melting seasons.Therefore,the variability of wintertime MY ice plays a vital role in modulating the variations in the Arctic sea ice minimum extent during the following summer.As a response,the ice-ocean-atmosphere interactions may be significantly affected by the variations in the MY ice cover.Satellite observations are characterized by their capability to capture the spatiotemporal changes of Arctic sea ice.During the recent decades,many active and passive sensors onboard a variety of satellites(QuikSCAT,ASCAT,SSMIS,ICESat,CryoSat-2,etc.)have been used to monitor the dramatic loss of Arctic MY ice.The main objective of this study is to outline the advances and remaining challenges in monitoring the MY ice changes through the utilization of multiple satellite observations.We summarize the primary satellite data sources that are used to identify MY ice.The methodology to classify MY ice and derive MY ice concentration is reviewed.The interannual variability and trends in the MY ice time series in terms of coverage,thickness,volume,and age composition are evaluated.The potential causes associated with the observed Arctic MY ice loss are outlined,which are primarily related to the export and melting mechanisms.In addition,the causes to the MY ice depletion from the perspective of the oceanic water inflow from Pacific and Atlantic Oceans and the water vapor intrusion,as well as the roles of synoptic weather,are analyzed.The remaining challenges and possible upcoming research subjects in detecting the rapidly changing Arctic MY ice using the combined application of multisource remote sensing techniques are discussed.Moreover,some suggestions for the future application of satellite observations on the investigations of MY ice cover changes are proposed. | BI Haibo LIANG Yu WANG Yunhe LIANG Xi ZHANG Zehua DU Tingqin YU Qinglong HUANG Jue KONG Mei HUANG Haijun | 2020 | Journal of Oceanology and Limnology2020，38，4： | 2 |
| 19 | Recent satellite-derived sea ice volume flux through the Fram Strait: 2011–2015显示文摘The Fram Strait(FS) is the primary region of sea ice export from the Arctic Ocean and thus plays an important role in regulating the amount of sea ice and fresh water entering the North Atlantic seas. A 5 a(2011–2015) sea ice thickness record retrieved from Cryo Sat-2 observations is used to derive a sea ice volume flux via the FS. Over this period, a mean winter accumulative volume flux(WAVF) based on sea ice drift data derived from passivemicrowave measurements, which are provided by the National Snow and Ice Data Center(NSIDC) and the Institut Francais de Recherche pour d'Exploitation de la Mer(IFREMER), amounts to 1 029 km^3(NSIDC) and1 463 km^3(IFREMER), respectively. For this period, a mean monthly volume flux(area flux) difference between the estimates derived from the NSIDC and IFREMER drift data is –62 km^3 per month(–18×10~6 km^2 per month).Analysis reveals that this negative bias is mainly attributable to faster IFREMER drift speeds in comparison with slower NSIDC drift data. NSIDC-based sea ice volume flux estimates are compared with the results from the University of Bremen(UB), and the two products agree relatively well with a mean monthly bias of(5.7±45.9) km^3 per month for the period from January 2011 to August 2013. IFREMER-based volume flux is also in good agreement with previous results of the 1990 s. Compared with P1(1990/1991–1993/1994) and P2(2003/2004–2007/2008), the WAVF estimates indicate a decline of more than 600 km^3 in P3(2011/2012–2014/2015). Over the three periods, the variability and the decline in the sea ice volume flux are mainly attributable to sea ice motion changes, and second to sea ice thickness changes, and the least to sea ice concentration variations. | BI Haibo WANG Yunhe ZHANG Wenfeng ZHANG Zehua LIANG Yu ZHANG Yi HU Wenmin FU Min HUANG Haijun | 2018 | Acta Oceanologica Sinica2018，37，9： | 2 |
| 20 | Biophotonic Activity and Transmission Mediated by Mutual Actions of Neurotransmitters are Involved in the Origin and Altered States of Consciousness显示文摘Dear Editor Despite remarkable advances in our understanding of brain functions,the neural substrates and correlates of consciousness remain unclear[1].It has been argued that classical physics is intrinsically incapable of explaining the holistic aspects of consciousness,especially its | Weitai Chai Zhengrong Han Zhuo Wang Zehua Li Fangyan Xiao Yan Sun Yanfeng Dai Rendong Tang Jiapei Dai | 2018 | Neuroscience Bulletin2018，34，3： | 2 |
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