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25篇 您的检索式:作者名="Takeuchi P T"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Heart allografts in mouse systems:the defferential activation of TH2-like effector cells in peripheral tolerance 显示文摘Takeuchi T lowry R P Konieczny B 1992Transplantation1992,53,:1
3CD11b/CD18 acts in concert with CDI4 and Toll-like receptor (TL) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression显示文摘Perera P Y Mayadas T N Takeuchi O 2001J Immunol2001,166,:1
4Characters of microencapsulated PCM slurry as a heat transfer fluid显示文摘Yasushi Yamagishi Hiromi Takeuchi Alexander T P 0,,04:1
5Discrimination of bacterial lipoproteins by Toll-like receptor 6 显示文摘TAKEUCHI O KAWAI T MUHLRADT P F 2001Int Immunol2001,13,7:1
6Discrimination of bacterial lipoproteins by toll-like receptor 6显示文摘Takeuchi O Kawai T Muhlradt P F 2001Int Immunol2001,13,7:1
7Optimal source distribution for binaural synthesis over loudspeakers显示文摘Takeuchi T Nelson P A 2001Acoustics Research Letters Online2001,2,:1
8Discrimination of bacterial lipoproteins by Toll like receptor 6显示文摘Takeuchi O Kawai T Muhlradt P F 2001Int Immunol2001,13,:1
9Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury 显示文摘Uchiyama T Miura T Takeuchi H Dairaku T Komuro T Kawamura T Kondo Y Benda L Sychrovsky V Bour P Okamoto I One A Tanaka Y 2012Nucleic Acids Res2012,40,12:1
10Discrimination of bacterial lipoproteins by Toll-like receptor 6 显示文摘TAKEUCHI O KAWAI T MUHLRADT P F 2001Int Immunol2001,13,7:1
11CDllb/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4 to elicit full lipopolysaceharide and taxol-inducible gene expression 显示文摘Perera P Y Mayadas T N Takeuchi O 2001Immunol2001,166,1:1
12Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus 显示文摘Nierman WC Pain A Anderson MJ Wortman JR Kim HS Arroyo J Berriman M Abe K Archer DB Bermejo C Bennett J Bowyer P Chen D Collins M Coulsen R Davies R Dyer PS Farman M Fedorova N Fedorova N Feldblyum TV Fischer R Fosker N Fraser A Garcla JL Garcia MJ Goble A Goldman GH Gomi K Griffith- Jones S Gwilliam R Haas B Haas H Harris D Horiuchi H Huang J Humphray S Jim6nez J Keller N Khouri H Kitamoto K Kobayashi T Konzack S Kulkarni R Kumagai T Lafon A Latgo JP Li W Lord A Lu C Majoros WH May GS Miller BL Mohamoud Y Molina M Monod M Mouyna I Mulligan S Murphy L O'Neil S Paulsen I Pefialva MA Pertea M Price C Pritchard BL Quail MA Rabbinowitsch E Rawlins N Rajandream MA Reichard U Renauld H Robson GD Rodriguez de Cordoba S Rodriguez-Pefia JM Ronning CM Putter S Salzberg SL Sanchez M Sfnchez-Ferrero JC Saunders D Seeger K Squares R Squares S Takeuchi M Tekaia F Turner G Vazquez de Aldana CR Weidman J White O Woodward J Yu JH Fraser C Galagan JE Asai K Machida M Hall N Barrell B Denning DW 2005Nature2005,438,7071:1
13Discrimination of bacterial lipoproteins by Toll-like receptor 6 显示文摘Takeuchi O Kawai T Muhlradt P F 2001Int Immunol2001,13,7:1
14Ethnicdifferences in the perception of barriers to help seeking显示文摘TAKEUCHI D T LEAF P J KUOH 1998Social Psychiatry and Psychiatric Epidemiology1998,23,:1
15Degradation of phenol by underwater pulsed corona discharge in combination with TiO2 photocatalysis显示文摘P Lukes M Clupek P Sunka F Peterka T Sano N Negishi S Matsuzawa K Takeuchi 2005Research on Chemical Intermediates (-)2005,,4:1
16Neurons in the hilus region of the rat hippocampus are depleted in number by exposure to alcohol during early postnatal life显示文摘Miki T Harris S J Wilce P Takeuchi Y Bedi KS 0,,03:1
17Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha显示文摘Macchia P E Takeuchi Y Kawai T 2001Proc Natl Acad Sci2001,98,:1
18The effect of the timing of ethanol exposure during early postnatal life on total number of Purkinje cells in rat cerebellum显示文摘Miki T Harris S Wilce P Takeuchi Y Bedi KS 0,,3:1
19Modulation of behavioral performance of prepubertal monkey by moderate dietary zinc dep rivation 显示文摘Gdub M S Gershw M E Takeuchi P T 1994A M J Clin Nutr1994,60,2:1
20Two sets of human-tropic pig retrovirus显示文摘Le T P Stoye J P Takeuchi Y 1997Nature1997,389,:1
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