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20篇 您的检索式:作者名="Susan Walker"
    题名 作者 年代 出处 被引量
1The value of limited computed tomography with rectal contrast in the diagnosis of acute appendicitis 显示文摘Susan Walker Willian Haun Jeffrey Clark 2000The American Journal of Surgery2000,180,6:1
2Effects of early childhood psychosocial stimulation and nutritional supplementation on cognition and education in growth-stunted Jamaican children: prospective cohort study显示文摘Susan P Walker Susan M Chang Christine A Powell Sally M Grantham-McGregor 2005The Lancet2005,,9499:1
3Latex ves- sels with customized compliance for use in arterial flow models 显示文摘Richard D Walker Roy E Smith Susan B Sheriff 1999PhysiolMeas1999,20,6:1
4Analysis of fiducials implanted during EUS for patients with localized rectal cancer receiving high-dose rate endorectal brachytherapy显示文摘Shalini Moningi Amanda J. Walker Ashkan A. Malayeri Lauren M. Rosati Susan Gearhart Jonathan Efron Elizabeth Wick Nilofer Azad Elwood P. Armour Yi Le Joseph M. Herman Eun Ji Shin 2014Gastrointestinal Endoscopy2014,,:1
5A randomized, double-blind, placebo-controlled, crossover study to assess the immediate effect of sublingual glyceryl trinitrate on the ankle brachial pressure index, claudication, and maximum walking distance of patients with intermittent claudication显示文摘 Tennant Susan 1998J Vasc Surg1998,28,5:1
6Trans fatty acids in a range of UK processed foods显示文摘Mark Roe Hannah Pinchen Susan Church Selvarani Elahi Margaret Walker Melanie Farron-Wilson Judith Buttriss Paul Finglas 2012Food Chemistry2012,,:1
7Forming a community partnership to enhance education in sustainability显示文摘Susan Allen-Gil Liz Walker Garry Thomas Tom Shevory Shapiro Elan 2005International Journal of Sustainability in Higher Education2005,,4:1
8Latex vessels with customized compliance for use in arterial flow models 显示文摘Richard D Walker Roy E Smith Susan B Sheriff 1999Physiol Meas1999,20,6:1
9An action spectrum (290 -320 nm) for TNF_ protein in human skin in vivo suggests that basal-layer epidermal DNA is the chromophore显示文摘Susan L Walker Antony R 2007Pnas2007,104,19:1
10Why Do Parents Become Involved in Their Children's Education? Implications for School Counselors显示文摘Walker Joan M.T Shenker Susan S HooverOempsey Kathleen V 0,,10:1
11Why Do Parents Become Involved in Their Children's Education? Implications for School Counselors显示文摘Walker Joan M.T Shenker Susan S HooverOempsey Kathleen V 0,,10:1
12Abstraction and Abstraction Control in Scotland显示文摘Ian A Fox Susan Walker 2002Science of the Total Environment2002,294,1:1
13Hepatitis B vaccine response among infants born to hepatitis B surface antigen-positive women显示文摘Stephen C. Ko Sarah F. Schillie Tanja Walker Steven L. Veselsky Noele P. Nelson Julie Lazaroff Susan Crowley Cristina Dusek Khalilah Loggins Kenneth Onye Nancy Fenlon Trudy V. Murphy 2014Vaccine2014,,:1
14Vertebral Artery Ostium Atherosclerotic Plaque as a Potential Source of Posterior Circulation Ischemic Stroke: Result From Borgess Medical Center Vertebral Artery Ostium Stenting Registry显示文摘Firas Al-Ali Tom Barrow Li Duan Anne Jefferson Susan Louis Kim Luke Kevin Major Sandy Smoker Sarah Walker Margaret Yacobozzi 2011Stroke2011,,9:1
15The Bacteriology of Pouchitis: A Molecular Phylogenetic Analysis Using 16S rRNA Gene Cloning and Sequencing显示文摘Simon D. McLaughlin Alan W. Walker Carol Churcher Susan K. Clark Paris P. Tekkis Matthew W. Johnson Julian Parkhill Paul J. Ciclitira Gordon Dougan Ralph John Nicholls Liljana Petrovska 2010Annals of Surgery2010,,1:1
16Child development: risk factors for adverse outcomes in developing countries显示文摘Susan P Walker Theodore D Wachs Julie Meeks Gardner Betsy Lozoff Gail A Wasserman Ernesto Pollitt Julie A Carter 2007The Lancet2007,,9556:1
17脊髓和周围神经系统中内源性大麻酚类花生四烯甘油的液相层析-质谱检测(英文)显示文摘AIM: To develop a sensitive method for measuring theputative endocannabinoid 2-arachidonylglycerol (2-AG)in the peripheral and ceatral nervous system.METHODS: A method using atmospheric pressurechemical ionization (APCI) liquid chromatography/mass spectrometry (LC/MS ) was developed todetermine the levels of 2-AG in methanol extracts of therat lumar spinal cord, dorsal root ganglion (DRG),and sciatic nerve. RESULTS: 2-AG was detectedwith high sensitivity and minimal sample preparation.The levels in the tissues analyzed were ≤pmol/mg wetweight. Similar levels were found in the spinalSusan M HUANG Nicole M STRANGMAN J Michael WALKER 1999中国药理学报1999,20,12:0
18舞动浪漫显示文摘舞蹈中的瞬间就宛如被甩到炙热的烤架上的水滴,猛地一下,嘶嘶一响,水滴就蒸发了,丝毫没有留下它曾经存在过的痕迹。Susan Walker 乐在其中 2008疯狂英语(阅读版)2008,0,10:0
19Fatty liver in H63D homozygotes with hyperferritinemia显示文摘为了学习 H63D 变化的临床的相互关联,我们分析了在一个工作分派实验室通过变化分析识别的 H63D 同质接合体的显型。样品为 HFE 分析提交了的 366 血的一个总数为 C282Y 和 H63D 变化被屏蔽。四 H63D 同质接合体被识别。所有提起了浆液含铁锡但是正常转铁蛋白浸透。他们为肝炎 B 和 C 是否定的,仅仅一个病人消费了过量酒精。在所有 4 个盒子中, ultrasonography 揭示了脂肝。在二个病人,肝活体检视与不平常的分布和宏被做并且出现温和铁质沉着病小囊的脂肪变性。这些数据证实在脂肝, hyperferritinaemia 和增加的肝的铁之间的协会,但是不澄清铁质沉着病是否为 H63D 变化与脂肪变性而非纯合性有关。有脂肝的病人可以在 H63D 纯合性的表达式的人口研究复杂化数据的解释。Giada Sebastiani Daniel F Wallace Susan E Davies Vasu Kulhalli Ann P Walker James S Dooley 2006World Journal of Gastroenterology2006,12,11:0
20A nano-enhanced vaccine for metastatic melanoma immunotherapy显示文摘Aim:Despite the huge advancements in cancer therapies and treatments over the past decade,most patients with metastasized melanoma still die from the disease.This poor prognosis largely results from resistance to conventional chemotherapies and other cytotoxic drugs.We have previously identified 6 antigenic peptides derived from melanomas that have proven efficacious for activating CD4+T cells in clinical trials for melanoma.Our aim was to improve pharmacodynamics,pharmacokinetic and toxicological parameters by individually encapsulating each of the 6 melanoma helper peptides within their own immunogenic nanoliposomes.Methods:We modified these liposomes as necessary to account for differences in the peptides’chemical properties,resulting in 3 distinct formulations.To further enhance immunogenicity,we also incorporated KDO2,a TLR4 agonist,into the lipid bilayer of all nanoliposome formulations.We then conducted in vivo imaging studies in mice and ex vivo cell studies from 2 patient samples who both strongly expressed one of the identified peptides.Results:We demonstrate that these liposomes,loaded with the different melanoma helper peptides,can be readily mixed together and simultaneously delivered without toxicity in vivo.These liposomes are capable of being diffused to the secondary lymphoid organs very quickly and for at least 6 days.In addition,we show that these immunogenic liposomes enhance immune responses to specific peptides ex vivo.Conclusion:Lipid-based delivery systems,including nanoliposomes and lipid nanoparticles,have now been validated for pharmacological(small molecules,bioactive lipids)and molecular(mRNA,siRNA)therapeutic approaches.However,the utility of these formulations as cancer vaccines,delivering antigenic peptides,has not yet achieved the same degree of commercial success.Here,we describe the novel and successful development of a nanoliposome-based cancer vaccine for melanoma.These vaccines help to circumvent drug resistance by increasing a patient’s T cell response,making them more susceptible to checkpoint blockade therapy.Katelyn E.Salotto Walter C.Olson Jr Karlyn E.Pollack Anuradha Illendula Elishama Michel Sydney Henriques Todd Fox Susan Walker Marya Dunlap-Brown Craig L.Slingluff Jr Mark Kester Helena W.Snyde 2022Cancer Drug Resistance2022,5,3:0
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