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| 1 | Kinetics of thermal inactivation of catalase in the presence of additives显示文摘 | Anca Ruxandra Cantemir Adina Raducan Mihaela Puiu | | 0，，3： | 1 |
| 2 | Identification of a second aryl phosphate-binding site in protein-tyrosine phosphataselB: Aparadigm for inhibitor design显示文摘 | Puius Y A Zhao Y Sullivan M | 1997 | Proceedings of the Nationol Academy of Sciences USA1997，94，13： | 1 |
| 3 | Genome sequence of the Wolbaehia endosymbiont of Culex quiuquefasciatus JHB 显示文摘 | Salzberg SL Puiu D Sommer DD | 2009 | Journal of Bacteriology2009，191，5： | 1 |
| 4 | Determining the driving torques of the robots with delta 3DOF parallel structure by using the MSC ADAMS software pack显示文摘 | Andrioaia D Rotar D Puiu G | 2013 | Applied Mechanics and Materials2013，，332： | 1 |
| 5 | Colour sensor for (bio)chemical/biological discrimination and detection 显示文摘 | Daniel Puiu Poenar Tse Man Siu Tan Ooi Kiang | 2002 | Materials Science in Semiconductor Processing2002，5，1： | 1 |
| 6 | A new model to estimate friction torque in a ball screw system 显示文摘 | OLARU D PUIU G C BALAN L C | 2006 | Product Engineering2006，，3： | 1 |
| 7 | Structural basis of plasticity in protein tyrosine phosphatase 1B substraterecognition显示文摘 | Puius YA Vetter SW | 2000 | Biochemistry2000，39，28： | 1 |
| 8 | B2 adrenergic receptors and morphological changes of the enteric nervous system in colorectal adenocarcinoma显示文摘AIM To study the morphology of the enteric nervous system and the expression of beta-2 adrenergic(B2A) receptors in primary colorectal cancer.METHODS In this study, we included forty-eight patients with primary colorectal cancer and nine patients for control tissue from the excision of a colonic segment for benign conditions. We determined the clinicopathological features and evaluated the immunohistochemical expression pattern of B2 A receptors as well as the morphological changes of the enteric nervous system(ENS). In order to assess statistical differences, we used the student t-test for comparing the means of two groups and one-way analysis of variance with Bonferroni's post hoc analysis for comparing the means of more than two groups. Correlations were assessed using the Pearson's correlation coefficient.RESULTS B2 A receptors were significantly associated with tumor grading, tumor size, tumor invasion, lymph node metastasis(P < 0.05), while there were no statistically significant associations with gender, CRC location and gross appearance(P > 0.05). We observed, on one hand, a decrease of the relative area for both Auerbach and Meissner plexuses with the increase of the tumor grading, and on the other hand, an increase of the relative area of other nervous elements not in the Meissner plexus or in the Auerbach plexus with the tumor grading. For G1 tumors we found that epithelial B2 A area showed an inverse correlation with the Auerbach plexus areas [r(14) =-0.531, P < 0.05], while for G2 tumors, epithelial B2 A areas showed an indirect variation with both the Auerbach plexus areas [r(14) =-0.453, P < 0.05] and the Meissner areas [r(14) =-0.825, P < 0.01]. For G3 tumors, the inverse dependence increased for both Auerbach [r(14) =-0.587, P < 0.05] and Meissner [r(14) =-0.934, P < 0.05] plexuses.CONCLUSION B2 A receptors play an important role in colorectal carcinogenesis and can be utilized as prognostic factors. Furthermore, study of the ENS in colorectal cancer may lead to targeted molecular therapies. | Raluca Niculina Ciurea Ion Rogoveanu Daniel Pirici Georgica-Costinel Tartea Costin Teodor Streba Cristina Florescu Bogdan Catalin Ileana Puiu Elena-Anca Tartea Cristin Constantin Vere | 2017 | World Journal of Gastroenterology2017，23，7： | 1 |
| 9 | Complete sequences of mitochondria genomes of 4edes aegypti and Culex quinquefasciatus and comparative analysis of mitochondrial DNA fragments inserted in the nuclear genomes显示文摘 | Behura SK Lobo NF Haas B deBruvn B Lovin DD Shumway MF Puiu D Romero-Severson J Nene V Severson DW | | 0，，10： | 1 |
| 10 | Sequencing and Assembly of the 22-Gb Loblolly Pine Genome显示文摘 | Zimin Aleksey Stevens Kristian A Crepeau Marc W Holtz-Morris Ann Koriabine Maxim Mar?ais Guillaume Puiu Daniela Roberts Michael Wegrzyn Jill L de Jong Pieter J Neale David B Salzberg Steven L Yorke James A Langley Charles H | 2014 | Genetics2014，，3： | 1 |
| 11 | Genome sequence of the Wolbachia endosymbiont of Culex quinquefasciatus JHB 显示文摘 | Salzberg S L Puiu D Sommer D D | 2009 | J Bac- teriol2009，191，5： | 1 |
| 12 | Laser sensors for trace gases in human breath显示文摘 | Puiu A Giubileo G Bangrazi C | | 0，，12： | 1 |
| 13 | Kinetics of thermal inactivation of catalase in the presence of additives显示文摘 | Cantemir A R Raducan A Puiu M | 2013 | Process Biochemistry2013，48，3： | 1 |
| 14 | A whole-genome assembly of the domestic cow?Bos taurus显示文摘 | Zimin A V Delcher A L Florea L Kelley D R Schatz M C Puiu D Hanrahan F Pertea G Van Tassell C P Sonstegard T S Marcais G Roberts M Subramanian P Yorke J A Salzberg S L | 2009 | Genome Biology2009，10，4： | 1 |
| 15 | Detection of saccharomyces cerevisiae immobilized on self-assembled monolayer (SAM) of alkanethiolate using electrochemical impedance spectroscopy显示文摘 | CHEN H HENG C K PUIU P D | 2005 | Analytica Chimica Acta2005，554，： | 1 |
| 16 | A whole-genome assembly of the domestic cow,bos taurus显示文摘 | Zimin AV Delcher AL Florea L Kelley DR Schatz MC Puiu D Hanrahan F Pertea G van Tassell CP Sonstegard TS Marcais G Roberts M Subramanian P Yorke JA Salzberg SL | | 0，，04： | 1 |
| 17 | A modular electrochemical peptide-based sensor for antibody detection显示文摘 | Puiu M Idili A Moscone D | 2014 | Chemical Communications2014，50，： | 1 |
| 18 | Health status during hospitalisations for chronic obstructive pulmonary disease exacerbations: the validity of the Clinical COPD Questionnaire 显示文摘 | Antoniu SA Puiu A Zaharia B | 2014 | Expert Rev Pharmacoecon Outcomes Res2014，14，2： | 1 |
| 19 | Kinetics of hydrogen peroxide decomposition by catalase: hydroxylic solvent effects显示文摘 | Adina Raducan Anca Ruxandra Cantemir Mihaela Puiu Dumitru Oancea | 2012 | Bioprocess and Biosystems Engineering2012，，9： | 1 |
| 20 | Health status during hospitali- sations for chronic obstructive pulmonary disease exacerbations:the validity of the Clinical COPD Questionnaire 显示文摘 | Antoniu SA Puiu A Zaharia B | 2014 | Expert Rev Pharma- coecon Outcomes Res2014，14，2： | 1 |
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