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| 1 | 香港华人妇女产后抑郁危险因素的前瞻性研究显示文摘目的:产后抑郁是一种常见的精神障碍,对产妇、新生儿和其它家庭成员导致广泛的伤害。产后抑郁的病因学研究大多是基于西方样本,对其中的社会文化原因也缺乏实证研究。本研究从人口学、心理社会及种族文化因素等方面探讨中国妇女产后抑郁症状学的决定因素。方法:在大学附属综合医院产前门诊连续收集登记的中国孕妇959例,从她们第一次产前检查开始评估(基线),以后分别在孕期的最后3个月、产后即刻和产后3个月时评估。调查涉及的危险因素分6个方面:人口学和社会经济背景,躯体疾病及精神疾病病史, 产前抑郁情绪,围生期应激源,人际关系,和种族文化环境。采用等级回归进行分析。因变量是产后3个月时的抑郁评分。结果:决定产后抑郁症状学的因素有:目前的生活事件,缺乏社会支持,婚姻不满意,既往有故意自伤史,以及产前存在抑郁情绪。婆媳关系不好和没有陪月在产后阶段也与抑郁评分高有关联。结论:西方研究所确立的产后抑郁危险因素大体适用于中国妇女。产褥期的社会文化特点同样对产妇情绪有影响。 | Dominic TS Lee Alexander SK Yip Sandra SM Chan Fiona FY Lee Tony YS Leung Tony KH Chung | 2005 | 中国心理卫生杂志2005，19，9： | 50 |
| 2 | Rabeprazole vs esomeprazole in non-erosive gastro-esophageal reflux disease: A randomized, double-blind study in urban Asia显示文摘AIM:Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with NERD.METHODS: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms noted.RESULTS: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated. | KM Fock EK Teo TL Ang TS Chua TM Ng YL Tan | 2005 | World Journal of Gastroenterology2005，11，20： | 8 |
| 3 | XPS and SEM studies of chromium oxide films chemically formed on stainless steel 316 L显示文摘 | P Stefanov D Stoychev M Stoycheva Ts Marinova | 2000 | Materials Chemistry and Physics2000，，2： | 4 |
| 4 | A novel orthotopic and metastatic mouse model of breast cancer in human mammary microenvironment(摘要)显示文摘 | Wang, J Xia, TS Liu, XA Ding, Q Du, Q Yin, H Wang, S | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 4 |
| 5 | 抗生素对鲤鱼生长和鱼体成分的影响显示文摘 | Ahmad,TS 李蓓 | 1990 | 湖北渔业1990，，3： | 4 |
| 6 | The discovery of eclogite dikes in low-greenschist facies volcaniclastic rocks of the Dabie Mountains显示文摘ECLOGITE occurs in different metamorphic rocks in the Dabie Mountains. Some dike-likeeclogite and garnet amphibolite were discovered when we investigated the newly founded low-greenschist facies volcaniclastic rocks in Changpu, Yuexi County and Siqian, Taihu County(fig.1). Coesite and quartz pseudomorphs exist in garnet and omphacite. By studying the oc-currence and petrography-mineralogy characteristic, we believe that the eclogite is of | Gao, TS Tang, JF Zhou, CT Hou, MJ Qian, CC | 1997 | Chinese Science Bulletin1997，42，20： | 3 |
| 7 | 环境铅暴露与血压的关系:2003-2010美国健康和营养调查显示文摘在铅暴露逐渐降低的环境下,该文通过分析2003-2010美国健康和营养调查资料,旨在研究血铅与血压、高血压的关系。纳入研究对象12 725人,其中非洲裔21.1%,西语裔20.5%,白人58.4%,女性48.7%。与非非洲裔比较,非洲裔的血压[126.5/71.9比123.9/69.6mm Hg(1mm Hg=0. | Hara A Thijs L Asayama K Gu YM Jacobs L Zhang ZY Liu YP Nawrot TS Staessen JA 刘莉 叶鹏 | 2014 | 中华高血压杂志2014，22，10： | 3 |
| 8 | miR147b:白细胞介素-1β介导的人类星形胶质细胞炎症中的新型关键调节因子显示文摘星形胶质细胞是大脑炎症过程的重要介质,可能在包括癫痫在内的几种神经系统疾病中起重要作用。星形胶质细胞中可生产几种miRNA,是炎症通路的关键调节因子,还可能用作治疗靶标。本研究将探索在体外IL-1β介导的炎症条件下,星形胶质细胞内生成的miRNA及其功能,并在人癫痫脑组织中验证。我们通过测序评估IL-1β刺激的人胎儿星形胶质细胞培养物中的miRNA和mRNA表达。使用miRNA模拟物在细胞培养物中过表达miRNA。使用原位杂交技术检测患有结节性硬化症复合体或颞叶癫痫伴海马硬化患者的切除脑组织中miRNA的表达。我们发现了2种差异表达的miRNA:miR146a和miR147b,它们与免疫/炎症反应相关基因的表达增加有关。既往有研究报道,在星形胶质细胞和结节性硬化复合细胞培养物中使用IL-1β刺激后,miR147b的过表达降低了促炎介质IL-6和COX-2的表达。miR146a和miR147b过表达降低了星形胶质细胞的增殖并促进人神经干细胞的神经元分化。miR147b在致癫痫脑中的星形胶质细胞中表达增加。由于其抗炎和恢复异常星形细胞增殖和促进神经元分化的能力,miR146a和miR147b作为与炎症相关的神经疾病(例如癫痫)的潜在治疗靶标值得进一步研究。 | van Scheppingen J Mills JD Zimmer TS Broekaart DWM Iori V Bongaarts A Anink JJ Iyer AM Korotkov A Jansen FE van Hecke W Spliet WG van Rijen PC Baayen JC Vezzani A van Vliet EA Aronica E 聂昊 | 2018 | 神经损伤与功能重建2018，13，12： | 3 |
| 9 | Comparative screening for thyroid disorders in old age in areas of iodine deficiency, long‐term iodine prophylaxis and abundant iodine intake显示文摘 | IstvánSzabolcs JanPodoba JoachimFeldkamp OrsolyaDohán IldikóFarkas MihálynéSajgó Krisztina I.Takáts MiklósGóth LászlóKovács KatalinKressinszky PeterHnilica GézaSzilágyi | 2003 | Clinical Endocrinology2003，，1： | 2 |
| 10 | B/N掺杂富含{001}晶面锐钛矿TiO_2的最佳可见光光电催化水氧化活性研究(英文)显示文摘本文以锐钛矿TiO_2微米球光催化材料为研究对象,其表面主要由{001}晶面组成,间隙掺杂硼原子在微米球中呈浓度梯度分布,浓度最高点位于表面.通过对其在氨气气氛、不同温度下(440–560℃)进行热处理,可实现氮替代晶格氧的掺杂,氮原子掺杂的浓度随着热处理温度的增加,由7.03增加到15.47 at%.随着掺杂氮浓度的增加,所得掺杂TiO_2微米球的可见光吸收强度相应提高.进一步研究所得掺杂TiO_2微米球的可见光光吸收、原子和电子结构与可见光光电催化水氧化活性的关联特性,发现在520℃下所得氮掺杂TiO_2的可见光光电催化水氧化活性最大,该样品吸收光谱的显著特征是在可见光区吸光率高,且没有与缺陷相关联的背底吸收. | 洪星星 康宇阳 甄超 康向东 尹利长 John TS Irvine 王连洲 刘岗 成会明 | 2018 | Science China Materials2018，61，6： | 2 |
| 11 | Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice显示文摘 | Kuida K Zheng TS Na S | | 0，，： | 2 |
| 12 | Chemical shift phase-difference and suppression magnetic resonance imaging techniques in animals, phantoms, and humans显示文摘 | Mitchell DG Kim I Chang TS | 1991 | Investigative Radiology1991，26，12： | 2 |
| 13 | Matching perspective views of a polyhedron using circuits显示文摘 | Gu WK Yang JY Huang TS | 1987 | IEEE Transaction on Pattern Analysis and Machine Intelligence1987，9，3： | 2 |
| 14 | Echovirus serotypes circulating in Malaysia from 2002 to 2013显示文摘Objective:To identify the circulating serotypes of human echovinis in Malaysia from 2002 in 2013.Methods:A toial of 31 retrospective samples from non-polio acute flacid paralysis,hand-food-and-mouth disease,viral meningitis and enterovirus cases were subjected to amplification of partial VPI gene by RT-PCR.Results:Sequencing and phylogeneiic analysis of the partial sequences identified presence of human echovinis and human coxsackie viruses.It was found that echovinis 11 was the commonly circulating serotype followed by echovinis6.echovinis 7.echovinis 3.echovinis 9.echovinis 30 and echovinis I in decreasing order.Additionally two types of human coxsackie virus isolates were detected which were coxsackie A24 and B3.Condusions:From the findings,there is a possibility that echovinis 11 is the predominant serotype among Malaysian patients with echovinis infection.However,a larger sample size will yield a more confident result to support this evidence.____________________ | Jeyanthi Suppiah TS Saraswathy Subramaniam Amry Khursany Ismail Apandi Yusof Zainah Sa'at | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，3： | 2 |
| 15 | Enhancement of angiogenesis by the implantation of self bone marrow cells in a rat ischemic heart model显示文摘 | Kobayashi T Hamano K Li TS | | 0，，： | 2 |
| 16 | Solution structure of the epithelial cadherin domain responsible for selective cell adhesion显示文摘 | Overduin M Harvey TS Bagby S Tong KI Yau P Takeichi M Ikura M | | 0，，： | 2 |
| 17 | 确定饱和油藏残余油饱和度的方法显示文摘 | Tang.,TS 苏开科 | 1996 | 国外油气科技1996，，2： | 2 |
| 18 | A Facile Procedure for the oxidative Coupling of 2-Naphthol and 2-Naphthalenethiol in Solid State显示文摘The oxidation of 2-naphthol and 2-naphthalenethiol to 1,1’ -bi-2-naphthol and bis-2naphthyl disulfide respectively has been carried out in excellent yields in solid state in the presence of Fe3+-montmorillonite or alumina-supported FeCl3. | Li, TS Zhang, ZH Yang, F Duan, HY Li, BZ Tewari, BB | 1998 | Chinese Chemical Letters1998，9，7： | 2 |
| 19 | Quantitation of minimal residual disease in multiple myeloma using allele-specific real-time PCR assay 显示文摘 | Rasmussen T Poulsen TS Honore L | 2000 | Exp Hematol2000，28，： | 2 |
| 20 | Severe acute respiratory syndrome(SARS):Infection control显示文摘 | Li TS Buckley TA Yap FH | 2003 | Lancet2003，361，： | 2 |
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