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| 1 | Chloramination of wastewater effluent: Toxicity and formation of disinfection byproducts显示文摘The reclamation and disinfection of waters impacted by human activities(e.g., wastewater effluent discharges) are of growing interest for various applications but has been associated with the formation of toxic nitrogenous disinfection byproducts(N-DBPs). Monochloramine used as an alternative disinfectant to chlorine can be an additional source of nitrogen in the formation of N-DBPs. Individual toxicity assays have been performed on many DBPs, but few studies have been conducted with complex mixtures such as wastewater effluents. In this work, we compared the cytotoxicity and genotoxicity of wastewater effluent organic matter(Ef OM) before and after chloramination. The toxicity of chloraminated Ef OM was significantly higher than the toxicity of raw Ef OM, and the more hydrophobic fraction(HPO)isolated on XAD-8 resin was more toxic than the fraction isolated on XAD-4 resin.More DBPs were also isolated on the XAD-8 resin. N-DBPs(i.e., haloacetonitriles or haloacetamides) were responsible for the majority of the cytotoxicity estimated from DBP concentrations measured in the XAD-8 and XAD-4 fractions(99.4% and 78.5%, respectively).Measured DBPs accounted for minor proportions of total brominated and chlorinated products, which means that many unknown halogenated compounds were formed and can be responsible for a significant part of the toxicity. Other non-halogenated byproducts(e.g.,nitrosamines) may contribute to the toxicity of chloraminated effluents as well. | Julien Le Roux Michael J.Plewa Elizabeth D.Wagner Maolida Nihemaiti Azra Dad Jean-Philippe Croué | 2017 | Journal of Environmental Sciences2017，29，8： | 8 |
| 2 | 人脑 Willis 动脉环后半环及其内穿支研究——附35例脑解剖资料显示文摘本文着重介绍35例人脑标本,对 Willis 动脉环的后半环及其内穿支作了仔细观察分析。从资料汇总表明:后交通动脉平均长度12.5mm,管径1.3~1.5mm,不只50%具有内穿支;大脑后动脉内侧段平均长度6~7mm,管径2~2.5mm,约90%以上具有内穿支;基底动脉平均管径3.58mm,约30%顶端(小脑上动脉起始以上)具有内穿支。研究结果:该区虽然存在较大的个体差异,但不能否定的是该区主要供血来自大脑后动脉内侧段的内穿支。 | 徐涛 ViGou Roux | 1991 | 中华神经外科杂志1991，7，4： | 8 |
| 3 | 心功能、难治性腹水和β受体阻滞剂对行肝移植的肝硬化患者预后的影响显示文摘【据《J Hepatol》2019年10月报道】题:心功能、难治性腹水和β受体阻滞剂对行肝移植的肝硬化患者预后的影响(作者Giannelli V等)非选择性β受体阻滞剂(NSBB)是否对终末期肝硬化和顽固性腹水的患者有害尚存在争议。假设如果只有一部分等待肝移植的心功能低下的患者应用NSBB,其病死率可能会有所增加。来自法国巴黎公立医院的Giannelli等纳入了1999年至2014年接受肝移植的584例肝硬化患者。 | 张晓雪 金清龙 GIANNELLI V ROUX O LAOUéNAN C | 2020 | 临床肝胆病杂志2020，36，3： | 7 |
| 4 | Laparoscopic sleeve gastrectomy:More than a restrictive bariatric surgery procedure?显示文摘Sleeve gastrectomy(SG) is a restrictive bariatric surgery technique that was first used as part of restrictive horizontal gastrectomy in the original Scopinaro type biliopancreatic diversion. Its good results as a single technique have led to a rise in its use, and it is currently the second most performed technique worldwide. SG achieves clearly better results than other restrictive techniques and is comparable in some aspects to the Roux-en-Y gastric bypass, the current gold standard in bariatric surgery. These benefits have been associated with different pathophysiologic mechanisms unrelated to weight loss such as increased gastric emptying and intestinal transit, and activation of hormonal mechanisms such as increased GLP-1 hormone and decreased ghrelin. The aim of this review was to highlight the salient aspects of SG regarding its historical evolution, pathophysiologic mechanisms, main results, clinical applications and perioperative complications. | David Benaiges Antonio Más-Lorenzo Albert Goday José M Ramon Juan J Chillarón Juan Pedro-Botet Juana A Flores-Le Roux | 2015 | World Journal of Gastroenterology2015，21，41： | 6 |
| 5 | Multidisciplinary management of Mirizzi syndrome with cholecystobiliary fistula: the value of minimally invasive endoscopic surgery显示文摘Mirizzi syndrome, a rare complication of gallstones, is defined by obstruction of the main bile duct. This obstruction may worsen and thus result in cholecystobiliary fistula. Surgical management of Mirizzi syndrome is complicated by the presence of inflamed tissue around the hepatic pedicle, making it impossible to distinguish between the main bile duct and the gallbladder. The surgeon's first task is to perform subtotal cholecystotomy(from the fundus of the gallbladder to the neck) without trying to locate the cystic duct. In a second step, the gallstones are extracted and the main bile duct is then repaired. In most cases, a T-tube is used to drain the main bile duct, and abdominal drainage is left in place(in case a bile fistula forms). This study concluded that preoperative drainage of the main bile duct in the treatment of Mirizzi syndrome types II and III is feasible and might help to decrease the postoperative complication rate. | Fabien Le Roux Charles Sabbagh Brice Robert Thierry Yzet Laurent Dugue Jean-Paul Joly Jean-Marc Regimbeau | 2015 | Hepatobiliary & Pancreatic Diseases International2015，14，5： | 6 |
| 6 | 动脉瘤性蛛网膜下腔出血患者的重症监护处理:神经危重症监护学会多学科共识会议的推荐意见显示文摘蛛网膜下腔出血(subarachnoidhemorrhage,SAH)是一种可对中枢神经系统造成毁灭性打击并对其他多个器官产生显著影响的急性脑血管病。SAH患者被常规收入重症监护病房并由多学科团队进行治疗。由于高质量研究证据的缺乏,使得治疗方法各异,可供选择的指导意见不多。现有的指南主要强调危险因素、预防、自然史以及再出血的预防,很少涉及SAH患者的重症监护问题。美国神经危重症监护学会组织了一次国际性多学科共识会议来探讨SAH的重症监护处理。根据发表的文章和研究领域,此次会议召集了来自欧洲和北美地区的神经重症监护科、神经外科、神经内科、介入神经放射科和神经麻醉科方面的专家。根据临床经验和制定实践指南方面的经验,选择4名经验丰富的神经重症监护专家组成评判委员会。应用推荐分级的评估、制定与评价(GradesofRecommendationsAssessment,DevelopmentandEvaluation,GRADE)系统进行文献回顾,结合参会者的经验、评判委员会的审评以及文献讨论产生推荐意见。应用GRADE系统制定推荐意见,其制定原则不仅强调研究资料的质量,而且还重视利弊权衡与实践转化。对SAH患者日常处理过程中面临的所有问题均提供指导和推荐意见,即使缺乏高质量的证据。 | Michael N. Diringer Thomas P. Bleck J. Claude Hemphill David Menon Lori Shutter Paul Vespa Nicolas Bruder E. Sander Connolly Jr Giuseppe Citerio Daryl Gress Daniel Hanggi Brian L. Hoh Giuseppe Lanzino Peter Le Roux Alejandro Rabinstein, Erich Schmut zhard Nino Stocchetti Jose I. Suarez Miriam Tresgiari Ming-Yuan Tseng Mervyn D. I. Vergouwen Stefan Wolf Gregory Zip fel 田飞(译) 宿 英英(译) | 2013 | 国际脑血管病杂志2013，21，5： | 5 |
| 7 | 一种超高分辨率遥感图像融合新算法显示文摘该文针对超高分辨率的全色光图像和多光谱图像的融合,提出了一种基于对应分析的图像融合新算法。该算法在对多光谱数据进行对应分析的基础上,利用冗余小波变换提取出全色光图像的空间细节信息并将其融入到成分空间。实验分别采用IKONOS和QuickBird数据,融合结果的目视效果与客观评价表明,相比现有同类融合方法,该方法能够在提高空间分辨率的同时更好地保持光谱特性,有效地减少了色彩失真的现象。 | 李旭 何明一 Michel Roux 卫保国 | 2009 | 电子与信息学报2009，31，12： | 5 |
| 8 | 减少丝光羊毛在染色中的损伤显示文摘阐述了染色时氯化丝光羊毛发生损伤的原因以及染色工艺条件对丝光羊毛损伤的影响。控制染色工艺参数可减少丝光羊毛染色时的损伤 ,交链类羊毛保护剂对丝光羊毛有较好的保护作用。通过正交实验得出 ,染色的pH值对丝光羊毛的强力影响最大 ,其次是保护剂 ,次之是染色的温度 ,最后是染色的时间。 | 蒋冶欣 朱泉 Roux Delphine | 2001 | 毛纺科技2001，29，2： | 5 |
| 9 | The use of wastewater analysis in forensic intelligence:drug consumption comparison between Sydney and different European cities显示文摘Wastewater analysis offers objective and complementary information to illicit drug agencies by monitoring patterns of illicit drug consumption.In this study,wastewater samples from three different wastewater treatment plants in Sydney,Australia were collected in March 2016.Ten targeted drugs were analysed and temporal and geographical analyses were performed to obtain a better understanding of the type and amount of illicit drugs consumed in Sydney in comparison with similar studies conducted around Australia and in Europe.Among the targeted drugs,methamphetamine was consumed the most,followed by cocaine and 3,4-methylenedioxymethamphetamine(MDMA).Weekly patterns were observed where a peak during the weekend was present.The geographical analysis showed differences between the regions targeted.This observation may be related to socio-demographic aspects.The comparison of our study to other data sources from Australia showed a high consumption of methamphetamine in Sydney and Western Australia.The comparison between Sydney and different European cities revealed a difference in consumption,which is in line with traditional market indicators.The information obtained through wastewater analysis provides complementary information regarding illicit drug consumption,the size,and the evolution of the illicit drug market.This,ultimately,will assist authorities in making informed decisions. | Anne Bannwarth Marie Morelato Lisa Benaglia Frederic Been Pierre Esseiva Olivier Delemont Claude Roux | 2019 | Forensic Sciences Research2019，4，2： | 4 |
| 10 | Nonlinear optical properties of integrated GeSbS chalcogenide waveguides显示文摘In this paper, we report the experimental characterization of highly nonlinear Ge Sb S chalcogenide glass waveguides.We used a single-beam characterization protocol that accounts for the magnitude and sign of the real and imaginary parts of the third-order nonlinear susceptibility of integrated Ge23 Sb7 S70(GeSbS) chalcogenide glass waveguides in the near-infrared wavelength range at λ =1580 nm. We measured a waveguide nonlinear parameter of 7.0±0.7 W^(-1)· m(-1), which corresponds to a nonlinear refractive index of n_2=0.93±0.08 × 10^(-18) m^2∕W,comparable to that of silicon, but with an 80 times lower two-photon absorption coefficient βTPA=0.010± 0.003 cm∕GW, accompanied with linear propagation losses as low as 0.5 dB/cm. The outstanding linear and nonlinear properties of Ge Sb S, with a measured nonlinear figure of merit FOMTPA=6.0 ±1.4 at λ =1580 nm, ultimately make it one of the most promising integrated platforms for the realization of nonlinear functionalities. | SAMUEL SERNA HONGTAO LIN CARLOS ALONSO-RAMOS ANUPAMA YADAV XAVIER LE ROUX KATHLEEN RICHARDSON ERIC CASSAN NICOLAS DUBREUIL JUEJUN HU LAURENT VIVIEN | 2018 | Photonics Research2018，6，5： | 3 |
| 11 | Combining Metabolomics and Gene Expression Analysis Reveals that Propionyl- and Butyryl- Carnitines Are Involved in Late Stages of Arbuscular Mycorrhizal Symbiosis显示文摘arbuscular mycorrhizal (AM ) 共生是在土壤真菌(Glomeromycota ) 和 theroots 之间的一个普遍 mutualistic 协会大多数植物种类。AM 真菌是要求其开发部分在他们的 planthost 的控制下面的 biotrophs。我们探索了可能性联合 metabolomic 和 transcriptomic 途径发现通常认为的 mycorrhiza-associatedmetabolites 调整 AM 真菌的开发。与 AM 真菌 Rhizophagus irregularis 开拓殖民地于的 Medicago truncatula 根的甲醇摘录被极端高效的液体层析(UHPLC ) 分析并且比较,高分辨率的集体 spectrometry (Q-TOF ) ,和 multivariate 统计辨别。我们检测了只在场的 71 联系 mycorrhiza 的 analytes 或在更充满 mycorrhizal 根的 least10 褶层。为了在这些 analytes 之中识别那些,那能调整 AM 真菌的开发,我们由准备、半准备的 HPLC 的 fractionated mycorrhizal 和 non-mycorrhizal 根摘录和 establishedhow 71 analytes 在部分之中被散布。然后,我们在发芽 sporesof R 上测试了部分的活动。由确定的 irregularis 知道为的 96 基因的表示他们的在 planta 表示模式多样。这些调查揭示在 mycorrhizal roots.The 结果积累的那 propionyl 肉毒碱和 butyryl 肉毒碱建议这二个分子在 planta 调整真菌的基因表示并且为进一步生物的 characterization.Key 词代表有趣的候选人: | Jerome Laparre | 2014 | Molecular Plant2014，7，3： | 3 |
| 12 | Ticagrelor inhibits the NLRP3 inflammasome to protect against inflammatory disease independent of the P2Y_(12 ) signaling pathway显示文摘Ticagrelor is the first reversibly binding oralP2Y_(12) receptor antagonist to inhibit platelet activation and has been approved by the Food and Drug Administration for the treatment of coronary artery disease. At present, the other pharmacological functions of ticagrelor remain poorly understood. The NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome plays a critical role in the innate immune system, but its excessive activation also contributes to the pathogenesis of complex diseases. In this study, we systematically examined the effects of ticagrelor on the NLRP3 inflammasome and found that ticagrelor inhibits NLRP3 inflammasome activation in macrophages independent of its classic inhibitory effect on theP2Y_(12) signaling pathway. Further mechanistic studies demonstrate that ticagrelor attenuates the oligomerization of apoptosis-associated speck-like protein containing a CARD (ASC) by blocking chloride efflux, an effect achieved through the degradation of chloride intracellular channel proteins (CLICs) and blockade of the translocation of CLICs to the plasma membrane. Moreover, experiments on lipopolysaccharide-induced sepsis and alum-induced peritonitis in mice confirmed that ticagrelor mitigates the severity of systemic inflammation independent ofP2Y_(12) receptor antagonism. Importantly, oral administration of ticagrelor rapidly and strongly inhibited NLRP3 inflammasome activation in peripheral blood mononuclear cells from patients with acute coronary syndrome. Overall, our study reveals a novel pharmacological function of ticagrelor in addition to its classic antiplatelet properties, which suggests that ticagrelor may serve as a potential therapeutic agent for use in NLRP3-associated diseases. | Bo Huang Yufeng Qian Shujun Xie Xianhua Ye Hanwen Chen Zhifeng Chen Lihuan Zhang Jinming Xu Hu Hu Shenglin Ma Paul Héroux Di Wang Han-Ming Shen Yihua Wu Dajing Xia | 2021 | Cellular & Molecular Immunology2021，18，5： | 3 |
| 13 | Comparison of tumor response by Response Evaluation Criteria in Solid Tumors (RECIST) and modified RECIST in patients treated with sorafenib for hepatocellular carcinoma显示文摘 | JulienEdeline EvelineBoucher YanRolland ElodieVauléon MarcPracht ChristophePerrin CatherineLe Roux Jean‐LucRaoul | 2011 | Cancer2011，，1： | 3 |
| 14 | Taxonomy and pathogenicity of Ceratocystis species on Eucalyptus trees in South China, including C. chinaeucensis sp. nov.显示文摘Commercial plantations of Eucalyptus species have been established in South China,especially during the past 20 years,to meet the needs of a rapidly growing national economy.As part of a survey of fungal diseases affecting Eucalyptus species in South China,Ceratocystis species were collected from Eucalyptus plantations in the GuangDong Province.The aims of this study were to identify these Ceratocystis isolates and to test their pathogenicity to Eucalyptus.The most aggressive isolates were also used to screen different species and clones of Eucalyptus for susceptibility to infection under field conditions.The fungi were identified based on morphology and through comparisons of DNA sequence data of the ITS,partialβ-tubulin and TEF-1αgene regions.Morphological and DNA sequence comparisons showed that isolates collected from Chinese Eucalyptus plantations represent two species,C.acaciivora in the C.fimbriata s.l.species complex and a previously undescribed species belonging to the C.moniliformis s.l.species complex,for which the name C.chinaeucensis sp.nov.is provided.In pathogenicity trials,both C.acaciivora and C.chinaeucensis gave rise to lesions on wounded Eucalyptus trees,and the former fungus was most pathogenic.Differences were also observed in the responses of different Eucalyptus clones to inoculation and this could be useful in reducing disease,if C.acaciivora should emerge as a pathogen in the future. | ShuaiFei Chen Marelize Van Wyk Jolanda Roux Michael J.Wingfield YaoJian Xie XuDong Zhou | 2013 | Fungal Diversity2013，，1： | 2 |
| 15 | A review on phase change materials integrated in building walls显示文摘 | Frédéric Kuznik Damien David Kevyn Johannes Jean-Jacques Roux | 2010 | Renewable and Sustainable Energy Reviews2010，，1： | 2 |
| 16 | Quality of life after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy: A prospective study of 216 patients显示文摘 | G. Passot N. Bakrin A.S. Roux D. Vaudoyer F.-N. Gilly O. Glehen E. Cotte | 2013 | European Journal of Surgical Oncology2013，，： | 2 |
| 17 | 显示文摘 | Roux R | 1995 | Laser Focus World1995，31，5： | 2 |
| 18 | Infliximab in spondylarthropathy--influence on bone density显示文摘 | Demis E Roux C Breban M | 2002 | Clin Exp Rheumatol2002，20，628： | 2 |
| 19 | Biosafety and biobanking: Current understanding and knowledge gaps显示文摘Infectious disease outbreaks,such as'Coronavirus disease 20190(COVID-19),can constitute major global health threats with far-reaching consequences.As outbreaks develop,the international scientific community must provide high-quality scientific research-ready biological samples to solve the existing clinical and epidemiological questions to better combat the pandemic.Such examples are provided by dedicated biobank facilities,the latter collecting increasingly high volumes of biological samples.However,the more significant concentrations of infectious or potentially infectious biological materials can create a safety risk.The current short report describes the first attempt to identify the published scientific works on biobanking and safety.Three broad thematic areas have been identified:the physical security relevant to staff and sample integrity,the data safety aspects,and the governance parameters relating to the previous two.While the current publications reflect a broad alignment with existing standards and best practices in the biobanking field,they also demonstrate an opportunity for further in-depth work on this field in the post-COVID-19 era. | Julie Roux Maissa Zeghidi Stephanie Villar Zisis Kozlakidis | 2021 | Biosafety and Health2021，3，5： | 2 |
| 20 | 外科减肥手术后高血压缓解和复发的预测因素显示文摘目前,只有很少量研究涉及外科减肥手术后高血压得到缓解和复发的影响因素,没有可用于预测高血压复发相关因素的信息。该研究的目的是评估在外科减肥手术后第1年和第3年里高血压的缓解情况和复发率,并寻找可能的预测因素。 | Benaiges D Sagué M Flores-Le Roux JA Pedro-Botet J Ramón JM Villatoro M Chillarón JJ Pera M Más A Grande L Goday A 陈云 | 2016 | 中华高血压杂志2016，24，9： | 2 |
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