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| 1 | Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma. | Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters | 2009 | World Journal of Gastroenterology2009,15,28: | 11 |
| 2 | Quality indicators for colonoscopy: Current insights and caveats显示文摘Colonoscopy is the diagnostic modality of choice for investigation of symptoms suspected to be related to the colon and for the detection of polyps and colorectal cancer(CRC). Colonoscopy with removal of detected polyps has been shown to reduce the incidence and mortality of subsequent CRC. In many countries, population screening programs for CRC have been initiated, either by selection of patients for colonoscopy with fecal occult blood testing or by offering colonoscopy directly to average-risk individuals. Several endoscopy societies have formulated quality indicators for colonoscopy. These quality indicators are almost always incorporated as process indicators, rather than outcome measures. This review focuses on the quality indicators bowel preparation, cecal intubation rate, withdrawal time, adenoma detection rate, patient comfort, sedation and complication rate, and discusses the scientific evidence supporting them,as well as their potential shortcomings and issues that need to be addressed. For instance, there is still no clear and generally accepted definition of adequatebowel preparation, no robust scientific evidence is available supporting a cecal intubation rate ≥ 90% and the association between withdrawal time and occurrence of interval cancers has not been clarified. Adenoma detection rate is currently the only quality indicator that has been shown to be associated with interval colorectal cancer, but as an indicator it does not differentiate between subjects with one or more adenoma detected. | Hendrikus JM Pullens Peter D Siersema | 2014 | World Journal of Gastrointestinal Endoscopy2014,6,12: | 7 |
| 3 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010,,9716: | 2 |
| 4 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010,,9716: | 2 |
| 5 | Spirin Resistance:Current Concepts显示文摘 | Peter JM Jane EF Alice KJ | 2004 | Rev Cardiovasc Med2004,5,: | 1 |
| 6 | The PPAR alpha- leukotrieneB4 pathway to inflammation control 显示文摘 | Devchand PR Keller H Peters JM | | Nature0,384,: | 1 |
| 7 | The anaphase promoting complex:proteolysis in mitosis and beyond显示文摘 | Peters JM | 2002 | Molecular Cell2002,9,: | 1 |
| 8 | Vitamin C supplementation reduces the incidence of postrace symptoms of upper-respiratory-tract infection in ultra-marathon runners显示文摘 | Peters EM Goetzsehe JM Bgrobbelaar B | 1993 | Am J Clin Nutr1993,57,: | 1 |
| 9 | defining the roles of nucleotide excision repair and recombination in the repair of DNA interstrand cross-links in mammalian cells显示文摘 | Inusha U Peter JM Peter HC | 2001 | Mol Cell Biol2001,20,21: | 1 |
| 10 | Receptor and nonreceptor-mediated organ-specific toxicity of di (2-ethylhexyl) phthalate (DEHP) in peroxisome proliferator-activated receptor alpha-null mice 显示文摘 | Peters JM Perella CM | 1998 | Toxicol Pathol1998,26,: | 1 |
| 11 | Moving cultural background to the fore- ground : an investigation of self - talk, performance, and persist- ence following feedback 显示文摘 | Peters HJ Williams JM | 2006 | Journal of Applied Sport Psychology2006,,3: | 1 |
| 12 | Coronavirus particle assembly: primary structure requirements of the membrane protein显示文摘 | Coruelis AM Kuo L Masters PS Vennena H and Peter JM | 1998 | J Virol1998,72,8: | 1 |
| 13 | Growth,adipose,brain,and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptorβ (δ)显示文摘 | Peters JM Lee SST Li W | | 0,,14: | 1 |
| 14 | Recepter and nonrecepter-nediated organ-specific toxicity of di(2-ethylhexyl) phthalate (DEHP) in peroxisone proliferator-activated receptor alpha-null mice显示文摘 | Peters JM Perella CM | 1998 | Toxicol Pathol1998,26,2: | 1 |
| 15 | Multiparameter flow cytometry in the diagnosis and management of acute leukemia显示文摘 | Peters JM Ansari MQ | 2011 | Arch Pathol Lab Med2011,135,1: | 1 |
| 16 | Imaging:Elementarytheory and preliminary experimental evaluation显示文摘 | Tang MX Mari JM Peter N | 2008 | Ultra-sound Med Biol2008,34,12: | 1 |
| 17 | Longitudinal study of the national kidney foundation's (NKF) kidney early wvaluation pro- gram (KEEP)显示文摘 | Ohmit SE Flack JM Peters RM | 2003 | J Am Soc Nephrol2003,14,72: | 1 |
| 18 | Sacral neuromodulation for the treatment of refractory interstitial cystitis : outcomes based on technique 显示文摘 | Peters KM Carey JM Konstandt DB | 2003 | Int Urogynecol J Pelvic Floor Dysfunct2003,14,4: | 1 |
| 19 | Multiparameter flow cytometry in the di- agnosis and management of acute leukemia显示文摘 | Peters JM Ansari MQ | 2011 | Arch Pathol Lab Med2011,135,1: | 1 |
| 20 | The anaphase-promoting complex:proteolysis in mitosis and beyond显示文摘 | Peters JM | 2002 | Mol Cell2002,9,: | 1 |