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| 1 | Evaluation of wound healing and antimicrobial potentials of Ixora coccinea root extract显示文摘Objective:To evaluate the wound healing and antimicrobial activity of root extracts of Ixora coccinea(I.coccinea).Methods:To investigate the wound healing efficacy of root extract of I.coccinea Linn,five groups of animals were divided each containing six animals.Two wound models including incision and excision wound models were used in this study.The parameters studied were tensile strength on incision wound model and in terms of wound contraction for excision wound model were compared with standard Nitrofurazone(NFZ) ointment(0.2%w/w). Six extracts(ethanol.aqueous,petroleum ether,benzene,chloroform and ethyl acetate ) of I. coccinea were screened for in vitro growth inhibiting activity against different bacterial strains riz. Staphylococcia aureus.Bacillus pumilius,Enterococcus facialis.Escherichia coli,Salmonella typhi and Pseudomonas aeruginosa and fungi Candida albicans and Aspergillus niger were compared with the standard drugs ciprofloxacin and chloramphenicol for antibacterial and griscofulvin for antifungal screening.The serial dilution and cup(or) well plate methods were used for the antimicrobial study and MIC was determined.Results:The ethanolic extract showed significant (P<0.001) wound healing activity when compared to standard drug NFZ with respect to normal control group.Amongst all.ethanolic extract showed highly significant antibacterial activity against all bacterial strains used in this study when compared to standard.The aqueous extract showed moderate significant inhibition against all bacterial strains when compared to standard. All the extracts were shown negligible activity against the fungal strains used in this study. Conclusions:The ethanolic root extract of I.coccinea showed pronounced wound healing and antibacterial activity.The probable reason to heal the wound was that the external application of the extract prevented the microbes to invade through the wound thus the protection of wound occurs against the infection of the various organisms. | Nagaraj Selvaraj Baskar Lakshmanan Papiya Mitra Mazumder Muthukumar Karuppasamy Simon Santosh Jena Ashok Kumar Pattnaik | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，12： | 5 |
| 2 | Heat and mass transfer study in fluidized bed granulation-Prediction of entry length显示文摘Fluidized bed granulation is a process by which granules or coated particles are produced in a single piece of equipment by spraying a binder as solution, suspension, or melt on the fluidized powder bed. Heat and mass transfer correlation useful for designing a granulator has been derived based on the equivalence of evaporation rate of the liquid to the heat transferred from hot gas to particles: (m/A)Dp2λ/(Lmf(1- εmf)(Tg-Tl)Kg)=hDp/Kg . This equation is applied to data on granulation experiments by different workers to calculate Reynolds number and Nusselt number to obtain a relation between heat and mass transfer from gas to particles during granulation on a logarithmic scale from which the following empirical relation is obtained: Nu = 0.0205Re1.3876 which is comparable to Kothari's correlation Nu = 0.03Re1.3. By using the heat and mass transfer correlation obtained, the entry length, that is the length of granulator up to which effective heat transfer from gas to bed particles takes place, is estimated, which is also validated with experimental study. The correct estimation of entry length is useful in optimal design of a granulator. | Papiya Roy Manish Vashishtha Rajesh Khanna Duvvuri Subbarao | 2009 | Particuology2009，7，3： | 2 |
| 3 | Spermidine treatment to rice seedlings recovers salinity stress-induced damage of plasma membrane and PM-bound H+-ATPase in salt-tolerant and saltsensitive rice cuhivars显示文摘 | Papiya R Kamala N SenGupta D N | 2005 | Plant Science2005，168，： | 1 |
| 4 | In vitro stable regeneration of onion and garlic from suspension culture and chromosomal instability in solid callus culture显示文摘 | Madhumita J. Mukhopadhyay Papiya Sengupta Sandip Mukhopadhyay Sumitra Sen | 2004 | Scientia Horticulturae2004，，1： | 1 |
| 5 | Influence of Musa Sapientum L. on Pharmacokinetic of Metformin in Diabetic Gastroparesis显示文摘Objective: To investigate the effect of Musa sapientum L.(MS) bark juice in diabetic gastroparesis and its effect on pharmacokinetic of metformin(MET). Methods: Diabetes was induced in rats by administering alloxan(120 mg/kg) saline solution and maintained for 8 week. All the 18 Sprague-Dawley rats were divided into three groups(n=6 in each group): normal control, diabetic control and MS bark juice. Assessment of diabetes was done by glucose oxidase-peroxidase method on the 3rd day of alloxan administration. The effects of MS bark juice(100 m L/kg) on gastric emptying time, intestinal transit time, contractility of fundus and pylorus as well as gastric acid secretion in chronic diabetic rats were observed after 8 weeks of alloxan administration. The effect of MS bark juice on the pharmacokinetic of orally administered single dose of MET(350 mg/kg) was evaluated on the 57 th day of protocol. Any drugs that may reduce the blood glucose level or influence the fibrinolytic system were not used in this study. Results: The MS bark juice significantly reduced the blood glucose level in the diabetic rats(P<0.01). There was significant decrease in the pylorus motility and increase in the gastric emptying time, intestinal transit time, contractility of fundus, gastric acid secretion in the MS bark juice treated group(P<0.01). There was significant decrease in the time at which drug at a maximum concentration, half life of drug and increase in the maximum concentration of drug in the plasma of MET in MS bark juice treated group as compared to diabetic control group(P<0.01). Conclusion: MS bark juice effectively manages diabetic gastroparesis and thereby improves the bioavailabilty of MET when administered with MS bark juice. | Vaibhav Darvhekar Alok Shiomurti Tripathi Shriramji G.Jyotishi Papiya Mitra Mazumder Pradeep G.Shelke | 2016 | Chinese Journal of Integrative Medicine2016，22，10： | 1 |
| 6 | Temperature Effects on a New Equation of State of Solids显示文摘 | Papiya B R Sushi B R | 2003 | J Phys Chem Solids2003，64，8： | 1 |
| 7 | Effect of an isolated activecompound (Cg-1) of Cassia glauca leaf on blood glucose, lipidprofile, and atherogenic index in diabetic rats 显示文摘 | Papiya MZ Mamta F Parcha V | 2009 | Indian JPharmacol2009，41，4： | 1 |
| 8 | Gastroprotective effect of Achyranthes aspera Linn,leaf on rats显示文摘Objective:The study was aimed al evaluating the antiulcer activity of ethanolic extract of Achyranthes aspera(EEAA) leaf.Methods:The anti-ulcer assays were performed on pylorus ligation and chronic ethanol induced ulcer model.The effects of the EEAA on gastric content volume,pH.free acidity,total acidity and ulcer index were evaluated.Results:The percentage of ulcer protection(59.55%and 35.58%) was significantly(P < 0.001) higher in the groups treated with the high dose of EEAA(600 mg/kg),it also reduced the volume of gastric juice and total acidity whereas,gastric pH was increased signiGcandy.Conclusions:The results of this study show significant gastroprotective activity of EEAA may be due to presence of phyto-constituents like flavanoids,saponins and tannins. | Ashish K Das Papiya Bigoniya Neelesh K Verma AC Rana | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，3： | 1 |
| 9 | Optical and mechanical properties of compaction and slip cast processed transparent polycrystalline spinel ceramics显示文摘 | Pandu Ramavath Papiya Biswas Kotikalapudi Rajeswari Madireddy Buchi Suresh Roy Johnson Gadhe Padmanabham Chandrashekhar Sadasiv Kumbhar Tapas Kumar Chongdar Nitin Madhusudan Gokhale | 2013 | Ceramics International2013，，： | 1 |
| 10 | In vitro evaluation of anti-acetylcholinesterase and free radical scavenging potential of leaf extracts of some selected medicinal plants显示文摘Objective: To evaluate the phytochemical present in various solvent extracts from leaves of Ocimum sanctum(L.), Swertia chirayita(L.), Butea monosperma(Lam.) and Stevia rebaudiana(Bert.) as well as antioxidant and anticholinergic activities employing different in vitro models. Methods: Total phenol content of diethyl ether, chloroform and methanolic extracts obtained from leaves of different medicinal plants was determined by Folin-Ciocalteau's spectrophotometric method. Moreover, antioxidant and anticholinergic studies were conducted by four different in vitro methods which included diphenyl picrylhydrazyl radical scavenging, 2,2-azinobis(3-ethylbezoline-6-sulphonic acid), reducing activity by ferrous reduced antioxidant power and anti-acetylcholinesterase assay, in order to ensure pharmacological potential of the plants. Results: The methanolic leaf extract of Ocimum sanctum showed the highest total phenol content which was(21.13±1.04) GAE/g DW and antioxidant activities compared to other plants with the IC50 value of 40.43 μg/mL in diphenyl picrylhydrazyl radical scavenging assay and 53.5 μg/mL in 2,2-azinobis(3-ethylbezoline-6-sulphonic acid) assay as well as metal ion reduced by(78.22±0.38) TE/g DW in ferrous reduced antioxidant power assay. The inhibition percentage of the anti-acetylcholinesterase assay was(94.22±0.26)%. Conclusions: The results of our current study show that Ocimum sanctum leaf is the most significant source of phytochemicals that possesses antioxidant and anticholinergic properties. However, further investigation on isolation and characterization of active compound which is responsible for the pharmacological potential is needed. | Annie Jessica Toppo Sheela Chandra Dhruv Jha Papiya Mitra Mazumder | 2019 | Asian Pacific Journal of Tropical Biomedicine2019，9，2： | 1 |
| 11 | Effects of extracellular matrix-degrading proteases matrix metalloproteinases-3 and -9 on spatial learning and synaptic plasticity显示文摘 | Meighan SE Meighan PC Papiya C | 2006 | Neurochem2006，96，5： | 1 |
| 12 | Spermidine treatment to rice seedlings recovers salinity stress-induced damage of plasma membrane and PM-bound H +-ATPase in salt-tolerant and salt-sensitive rice cultivars显示文摘 | Papiya R Kamala N SenGupta D N | 2005 | Plant Science2005，168，： | 1 |
| 13 | Eleutherine indica L. accelerates in vivo cutaneous wound healing by stimulating Smad-mediated collagen production显示文摘 | Aadesh Upadhyay Pronobesh Chattopadhyay Danswrang Goyary Papiya Mitra Mazumder Vijay Veer | 2013 | Journal of Ethnopharmacology2013，，2： | 1 |
| 14 | Role of antioxidants in phytomedicine with special reference to antidiabetic herbs显示文摘 | Papiya Mitra Mazumder Paramaguru Rathinavelusamy Dinakar Sasmal | 2012 | Asian Pacific Journal of Tropical Disease2012，，： | 1 |
| 15 | In situ synthesis and antibacterial activity of copper nanoparticle loaded natural montmorillonite clay based on contact inhibition and ion release显示文摘 | Biswajoy Bagchi Subrata Kar Sumit Kr. Dey Suman Bhandary Debasis Roy Tapas Kr. Mukhopadhyay Sukhen Das Papiya Nandy | 2013 | Colloids and Surfaces B: Biointerfaces2013，，： | 1 |
| 16 | Antimicrobial efficacy and biocompatibility study of copper nanoparticle adsorbed mullite aggregates显示文摘 | Biswajoy Bagchi Sumit Dey Suman Bhandary Sukhen Das Alakananda Bhattacharya Ruma Basu Papiya Nandy | 2012 | Materials Science & Engineering C2012，，7： | 1 |
| 17 | Doxapram Only Slightly Reduces the Shivering Threshold in Healthy Volunteers 显示文摘 | Ryu Komatsu Papiya Sengupta | 2005 | Anesth Analg2005，101，： | 1 |
| 18 | An Equation of State Applied to Solid up to 1 TPa显示文摘 | Sushil B R Papiya B R | 1999 | J Phys:Condens Matter1999，11，10： | 1 |
| 19 | Effect of Dendrophthoe falcata (L.f.) Ettingsh on female reproductive system in Wistar rats: a focus on antifertility efficacy显示文摘 | Shakti Prasad Pattanayak Papiya Mitra Mazumder | 2009 | Contraception2009，，3： | 1 |
| 20 | Spermidine treatment to rice seedlings recovers salinity stress-induced damage of plasma membrane and PM-bound H + -ATPase in salt-tolerant and salt-sensitive rice cultivars显示文摘 | Papiya Roy Kamala Niyogi D.N. SenGupta Bharati Ghosh | 2004 | Plant Science2004，，3： | 1 |
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