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| 1 | Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?显示文摘Frequent activation of phosphatidylinositol-3 kinases(PI3K)/Akt/m TOR signaling pathway in gastric cancer(GC) is gaining immense popularity with identification of mutations and/or amplifications of PIK3 CA gene or loss of function of PTEN,a tumor suppressor protein,to name a few; both playing a crucial role in regulating this pathway. These aberrations result in dysregulation of this pathway eventually leading to gastric oncogenesis,hence,there is a need for targeted therapy for more effective anticancer treatment. Several inhibitors are currently in either preclinical or clinical stages for treatment of solid tumors like GC. With so many inhibitors under development,further studies on predictive biomarkers are needed to measure the specificity of any therapeutic intervention. Herein,we review the common dysregulation of PI3K/Akt/m TOR pathway in GC and the various types of single or dual pathway inhibitors under development that might have a superior role in GC treatment. We also summarize the recent developments in identification of predictive biomarkers and propose use of predictive biomarkers to facilitate more personalized cancer therapy with effective PI3K/Akt/m TOR pathway inhibition. | Shikha Satendra Singh Wei Ney Yap Frank Arfuso Shreya Kar Chao Wang Wanpei Cai Arunasalam M Dharmarajan Gautam Sethi Alan Prem Kumar | 2015 | World Journal of Gastroenterology2015，21，43： | 36 |
| 2 | Changes in lipid metabolism in chronic hepatitis C显示文摘AIM: To investigate the relationship between certain biochemical parameters of lipid metabolism in the serum and steatosis in the liver.METHODS: The grade of steatosis (0-3) and histological activity index (HAI, 0-18) in liver biopsy specimens were correlated with serum alanine aminotransferase (ALT), total cholesterol and triglyceride levels in 142 patients with chronic hepatitis C (CH-C), and 28 patients with non-alcoholic fatty liver disease (NAFLD) without hepatitis C virus (HCV) infection. The serum parameters were further correlated with 1 797 age and sex matched control patients without any liver diseases.RESULTS: Steatosis was detected in 90 out of 142 specimens (63%) with CH-C. The ALT levels correlated with the grade of steatosis, both in patients with CH-C and NAFLD (P<0.01). Inserting the score values of steatosis as part of the HAI, correlation with the ALT level (P<0.00001) was found. The triglyceride and cholesterol levels were significantly lower in patients with CH-C (with and without steatosis), compared to the NAFLD group and to the virus-free control groups.CONCLUSION: Our study confirms the importance of liver steatosis in CH-C which correlates with lower lipid levels in the sera. Inclusion of the score of steatosis into HAI, in case of CH-C might reflect the alterations in the liver tissue more precisely, while correlating with the ALT enzyme elevation. | Katalin Jármay Gizella Karácsony András Nagy Zsuzsa Schaff | 2005 | World Journal of Gastroenterology2005，11，41： | 22 |
| 3 | Environmental application of three-dimensional graphene materials as adsorbents for dyes and heavy metals: Review on ice-templating method and adsorption mechanisms显示文摘The remediation of wastewater requires treatment technologies which are robust, efficient,simple to operate and affordable such as adsorption. Lately, three-dimensional(3D)graphene based materials have attracted significant attention as effective adsorbents for wastewater treatment. The intrinsic properties of 3D graphene structure such as large surface area and interconnected porous structure can facilitate the transport of pollutants into the 3D network and provide abundant active sites for trapping the pollutants. For the synthesis of 3D graphene structure, ice-templating is commonly practiced due to its facile steps, cost effectiveness and high scalability potential. This review covers the icetemplating fabrication technique for 3D graphene based materials and their application as adsorbents in eliminating dyes and heavy metals from aqueous media. The assembly mechanisms of the ice-templating fsynthesis are comprehensively discussed. Further discussion on the fundamental principles, critical process parameters and characteristics of ice-templated 3D graphene structures is also included. A thorough review on the mechanisms for batch adsorption of dyes and heavy metals is presented based on the structures and properties of the 3D graphene materials. The review further evaluates the dynamic adsorption in packed columns and the regeneration of 3D graphene based materials. | Kar Chiew Lai Lai Yee Lee Billie Yan Zhang Hiew Suchithra Thangalazhy-Gopakumar Suyin Gan | 2019 | Journal of Environmental Sciences2019，31，5： | 13 |
| 4 | Second-look arthroscopic evaluation of the articular cartilage after primary single-bundle and double-bundle anterior cruciate ligament reconstructions显示文摘在前面的十字形的系带( ACL ) reconstruction.No 报告关于比较变化在以后的软骨被出版了以后,背景几报告显示出关节的软骨退化的前进单个捆( SB )并且这研究的双捆( DB ) ACL reconstructions.The 目的是在 SB 和 DB ACL 以后评估关节的软骨变化由收到了 arthroscopic ACL 重建的 99 个病人回顾地是的秒看 arthroscopy.Methods | WANG Hai-jun AO Ying-fang CHEN Lian-xu GONG Xi WANG Yong-jian MA Yong LEUNG Kevin Kar Ming YU Jia-kuo | 2011 | Chinese Medical Journal2011，，21： | 12 |
| 5 | Proliferation and apoptosis property of mesenchymal stem cells derived from peripheral blood under the culture conditions of hypoxia and serum deprivation显示文摘增长和间充质的干细胞的 apoptosis 性质从外部血( PB-MSCs )导出的背景在剥夺在 vitro 调节以便在软骨 repair.Methods MSC 为自体同源的 PB-MSCs 应用评估可行性的组织缺氧和浆液下面被调查被 granulocyte 殖民地刺激动员进外部血因素( G-CSF )和 AMD3100.The 血样品从 rabbits.Adhered 房间的中央耳朵动脉被收集被红血球细胞溶解 b 获得当这二个条件联合了 together.Furthermore 时,效果更强壮, apoptosis 上的浆液剥夺的效果与 hypoxia.Conclusions PB-MSCs 的相比是更强壮的当 BM-MSCs.Their 区别和增长能力在关节的软骨修理的地里为局部缺血相关的房间治疗和织物工程使他们成为种子房间的新来源,拥有类似的显型。 | FU Wei-li JIA Zhu-qing WANG Wei-ping ZHANG Ji-ying FU Xin DUAN Xiao-ning LEUNG Kevin Kar Ming ZHOU Chun-yan YU Jia-kuo | 2011 | Chinese Medical Journal2011，，23： | 11 |
| 6 | On solubility and supersolubility of some classes of finite groups显示文摘Let G be a finite group and H a subgroup of G. Then H is said to be S-permutable in G if HP = PH for all Sylow subgroups P of G. Let HsG be the subgroup of H generated by all those subgroups of H which are S-permutable in G. Then we say that H is S-embedded in G if G has a normal subgroup T and an S-permutable subgroup C such that T ∩ H HsG and HT = C. Our main result is the following Theorem A. A group G is supersoluble if and only if for every non-cyclic Sylow subgroup P of the generalized Fitting subgroup F*(G) of G, at least one of the following holds: (1) Every maximal subgroup of P is S-embedded in G. (2) Every cyclic subgroup H of P with prime order or order 4 (if P is a non-abelian 2-group and H Z∞(G)) is S-embedded in G. | SHUM Kar Ping SKIBA Alexander N. | 2009 | Science China Mathematics2009，52，2： | 10 |
| 7 | Virological course of hepatitis A virus as determined by real time RT-PCR: Correlation with biochemical, immunological and genotypic profiles显示文摘瞄准:承担肝炎 A 的分析,并且相关病毒的负担,丙氨酸 aminotransferase (中高音) ,和有病毒血的持续时间的病毒的遗传型有控制调停房间的免疫的 CD4 (+)/ CD8 (+) 淋巴细胞人口的这些参数。方法:房间计数用用荧光在乙二胺四乙酸小瓶收集的新鲜全血被执行激活的房间 sorter。肝炎 A 病毒(HAV ) RNA 从血浆液被提取,抄录进 cDNA 并且由实时聚合酶链反应确定了并且是 genotyped 的颠倒。结果:在 11 个病人之中, 10 能完全被分析。这些, 3 有严重尖锐肝炎(s -- 啊) 并且剩余物有自我限制尖锐肝炎 A (啊哈) ,在第 4 d 上与有暴发性的疾病(脑病等级 IV ) 的一个病人一起死。中高音水平在啊哈两个都是显著地更高的(1070.9 +/- 894.3;P = 0.0014 ) 并且 s -- 啊(1713.9 +/- 886.3;P = 0.001 ) 与正常控制相比(23.6 +/- 7.2 ) 。在 s 的前凝血酶时间 -- 啊病人(21.0 +/- 2.0;P = 0.02 ) 比在啊哈显著地高(14.3 +/- 1.1;P = 0.44 ) 。在啊哈病人的 CD4 (+)/CD8 (+) 比率(1.17 +/- 0.11;P = 0.22 ) 并且 s -- 啊(0.83 +/- 0.12;P = 0.0002 ) 比在正常健康控制(1.52 ) 看低。有的自我限制盒子达到顶点在分析的开始的病毒的负担当时在 s -- 啊病人这发生在第 15 或第 30 d。在敏锐、严格的组,一耐心的各个属于遗传型 IA,与仍然是 8 个盒子属于遗传型 IIIA。唯一的暴发性的肝的失败大小写属于遗传型 IA。在自我限制感染的全部功课期间收集的 HAV 病毒的负担和中高音价值直接为 s 被相关,但是这不是事实 -- 啊病人。结论:基于小规模的研究, s 的固执地更高的病毒的负担 -- 啊可能由于减少的细胞免疫和溶血。病毒血的持续时间依赖于主人,当病毒的遗传型没在 AVH 和 s 的临床的结果有明显的角色 -- 啊盒子。 | Zahid Hussain Bhudev C Das Syed A Husain Sunil K Polipalli Tanzeel Ahmed Nargis Begum Subhash Medhi Alice Verghese Mohammad Raish Apiradee Theamboonlers Yong Poovorawan Premashis Kar | 2006 | World Journal of Gastroenterology2006，12，29： | 10 |
| 8 | SGLT-2 inhibitors in non-alcoholic fatty liver disease patients with type 2 diabetes mellitus: A systematic review显示文摘BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is a common comorbidity with type 2 diabetes.The existing therapeutic options for NAFLD are not adequate.Hypocaloric diet and exercise is the cornerstone of therapy in NAFLD.Pioglitazone is the only drug recommended in diabetes patients with biopsy proven non-alcoholic steatohepatitis.The frequent coexistence of NAFLD and type 2 diabetes with their combined adverse health consequences and inadequate therapeutic options makes it necessary to search for newer alternatives.AIM To assess the effect of sodium glucose cotransporter-2(SGLT-2)inhibitors on liver enzymes in type 2 diabetes patients with NAFLD.METHODS We searched PubMed/MEDLINE,Cochrane library,Google scholar,and Clinicaltrials.gov for the relevant articles to be included in this systematic review.Human studies done in type 2 diabetes patients with NAFLD treated with SGLT-2 inhibitors for at least 12 wk were included.Data from eight studies(four randomised controlled trials and four observational studies)were extracted and a narrative synthesis was done.A total of 214 patients were treated with SGLT-2 inhibitors in these studies(94 in randomised controlled trials and 120 in observational studies).RESULTS The primary outcome measure was change in serum alanine aminotransferase level.Out of eight studies,seven studies showed a significant decrease in serum alanine aminotransferase level.Most of the studies revealed reduction in serum level of other liver enzymes like aspartate aminotransferase and gamma glutamyl transferase.Five studies that reported a change in hepatic fat exhibited a significant reduction in hepatic fat content in those treated with SGLT-2 inhibitors.Likewise,among the three studies that evaluated a change in indices of hepatic fibrosis,two studies revealed a significant improvement in liver fibrosis.Moreover,there was an improvement in obesity,insulin resistance,glycaemia,and lipid parameters in those subjects taking SGLT-2 inhibitors.The studies disclosed that about 17%(30/176)of the subjects taking SGLT-2 inhibitors developed adverse events and more than 40%(10/23)of them had genitourinary tract infections.CONCLUSION Based on low to moderate quality of evidence,SGLT-2 inhibitors improve the serum level of liver enzymes,decrease liver fat,and fibrosis with additional beneficial effects on various metabolic parameters in type 2 diabetes patients with NAFLD. | Henith Raj Harsh Durgia Rajan Palui Sadishkumar Kamalanathan Sandhiya Selvarajan Sitanshu Sekhar Kar Jayaprakash Sahoo | 2019 | World Journal of Diabetes2019，10，2： | 9 |
| 9 | Efficacy of repetitive transcranial magnetic stimulation in treatmentresistant depression:the evidence thus far显示文摘Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as psychotherapy, which is often referred to as treatment-resistant depression. Neuromodulation techniques—like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation, may be useful augmenting techniques in depression, mostly recommended for treatment-resistant cases. Robust evidence exists regarding the efficacy of electroconvulsive therapy in the management of treatment-resistant depression;however, other techniques are understudied. TMS has been increasingly studied in various psychiatric disorders including depression. It has been approved by the US Food and Drug Administration for use in major depressive disorder. Over the past two decades, TMS has been studied in diverse groups of the population with depression using several research designs. This article gives an overview of the efficacy of repetitive TMS in treatment-resistant depression with the recent evidence. | Aditya Somani Sujita Kumar Kar | 2019 | General Psychiatry2019，32，4： | 9 |
| 10 | Expression patterns of cytokine,growth factor and cell cycle-related genes after partial hepatectomy in rats with thioacetamide-induced cirrhosis显示文摘瞄准:在与影响肝新生的因素的关系在对部分肝切除术的正常和硬变肝的回答检验差别。方法:肝硬化被 thioacetamide 的管理在老鼠导致。未经治疗的老鼠被用作控制。象肝脏硬化症的老鼠一样的控制老鼠受到 70% 部分肝切除术。在在肝切除术以后的不同时间点,肝被收集, cytokines,生长因素和房间周期蛋白质的层次被分析。结果:在肝切除术以后,当与直到 72 的控制相比 h 张贴肝切除术,肝脏硬化症的残余显著地表示了 cyclin D1,它的激酶搭挡, cdk4,和 cyclin E 的底层。当时,显著地, cyclin A 和 cdk2 的底层也被观察 cdk 禁止者, p27 显著地更高。另外,有的更低的 IL-6 比控制铺平的肝脏硬化症的组根本组织时间点直到 72 h 追随者切除术。结论:从我们的学习的数据证明在肝脏硬化症的残余的那个损害的肝新生与 cyclins 和 cdks 的低表示被联系。这可能是在将接着影响调整在新生过程期间涉及房间增长和新陈代谢的动态平衡的基因的抄写因素的行动的硬变肝残余的低 IL-6 层次的后果。 | Shu Yang Chon Kar Leow Theresa May Chin Tan | 2006 | World Journal of Gastroenterology2006，12，7： | 8 |
| 11 | Effect of β-blocker therapy in diabetic patients with stable coronary heart disease: a meta-analysis显示文摘Background β-blocker (BB) therapy is a cornerstone for the treatment of coronary heart disease (CHD).The evidence of the benefit from long-term BB therapy in diabetic patients with stable CHD is scarce.This meta-analysis summarizes the evidence relating to the BB therapy in diabetic patients with stable CHD.Methods A meta-analysis was performed according to PRISMA and MOOSE guidelines for reporting of systematic reviews of observational studies.PubMed,Embase,and Cochrane central were searched and two authors independently screened studies for eligibility.The quality of studies was assessed with the Newcastle Ottawa scale.The primary outcome of interest was all-cause mortality,cardiovascular (CV) mortality and major adverse cardiovascular events (MACE) in diabetic patients with and without BB therapy.A generic inverse variance model was used to pool odds ratio or hazards ratio from included studies to calculate the overall effect estimate.The significance threshold was set at P-value < 0.05.Heterogeneity was assessed by I2.Results Four non-randomized studies with 9515 participants were selected for the analyses.Four studies were post-hoc analyses of randomized controlled trials,and one article was an analysis of a nationally representative survey.In a fixed effects model,BB therapy in diabetic patients with stable CHD was found to be associated with increased risk of CV mortality,and MACE (27% and 32% respectively;P-value < 0.05) and was not associated with a reduction in all-cause mortality (HR 1.12;95% CI: 0.94–1.33;P-value = 0.22).Conclusion BB therapy in diabetic patients with stable CHD appears to be linked to higher mortality.Large randomized trials are needed in this population to confirm these findings. | Aaqib H Malik Suchith Shetty Kausik Kar Ramzi El Accaoui | 2019 | Journal of Geriatric Cardiology2019，16，3： | 7 |
| 12 | Experimental and Numerical Investigation of the Effects of Passive Vortex Generators on Aludra UAV Performance显示文摘A study of the effects of passive vortex generators (VGs) on Aludra unmanned aerial vehicle (UAV) aerodynamic characteristics is presented. Both experimental and numerical works are carried out where an array of VGs is attached on Aludra UAV's wing. The flow measurements are made at various angles of attack by using 3-axis component balance system. In the numerical investigation, the Reynolds-averaged Navier-Stokes (RANS) code FLUENT 6.3TM is used in the simulations with fully structured mesh with Spalart-Allmaras (S-A) turbulence model and standard wall function. The comparison between the experimental and numerical results reveals a satisfactory agreement. The parametric study shows that higher maximum lift coefficient is achieved when the VGs are placed nearer to the separation point. In addition to this, shorter spanwise distance between the VGs also increases the maximum lift coefficient, rectangular and curve-edge VG performs better than triangular VG. | Tan Kar ZHEN Muhammed ZUBAIR Kamarul Arifin AHMAD | 2011 | Chinese Journal of Aeronautics2011，24，5： | 6 |
| 13 | 热解炭去除污水中Cr(Ⅵ)(英文)显示文摘以胡桃壳在450℃裂解得到生物质炭BC450,以胡桃壳与20%沥青砂在450℃裂解得到BCTS20,与商业活性炭(CAC)进行对比研究去除污水中Cr(Ⅵ)的能力。与BC450相比,BCTS20具有更丰富的表面官能团。在适当条件下,BC450、BCTS20、CAC对Cr(Ⅵ)的去除率分别为80.47%、90.01%、95.69%。采用Langmuir、Freundlich、D-R模型研究吸附等温线,其中Langmuir模型最佳。BC450、BCTS20、CAC的最大Langmuir吸附容量分别为36.55、49.76、51.94 mg/g。这些炭材料对Cr(Ⅵ)的吸附可能归因于由离子交换、静电作用与螯合作用引起的化学过程。 | Türkan Altun Yakup Kar | 2016 | 新型炭材料2016，31，5： | 5 |
| 14 | 在现实生活中,有与无人值守时血压测量的差异显示文摘关于收缩压干预试验(systolic blood pressure intervention trial,SPRINT)的研究结果 是否具有普遍性的争论,引起了人们对无人值守诊室血压测量技术相当大的兴趣。现实世界中,与在熟悉的诊室里进行的传统血压测量方法相比,无人值守的血压测量值是否更低,尚无定论。 | 叶超毅 叶鹏 Bauer F Seibert FS Rohn B Bauer KAR Rolshoven E Babel N Westhoff TH | 2018 | 中华高血压杂志2018，26，3： | 5 |
| 15 | On U-orthodox semigroups显示文摘As a generalization of an orthodox semigroup in the class of regular semigroups, a type W semigroup was first investigated by El-Qallali and Fountain. As an analogy of the type W semi-groups in the class of abundant semigroups, we introduce the U-orthodox semigroups. It is shown that the maximum congruence μ contained in HU on U-orthodox semigroups can be determined. As a consequence, we show that a U-orthodox semigroup S can be expressed by the spined product of a Hall semigroup WU and a V-ample semigroup (T,V ). This theorem not only generalizes a known result of Hall-Yamada for orthodox semigroups but also generalizes another known result of El-Qallali and Fountain for type W semigroups. | SHUM Kar Ping | 2009 | Science China Mathematics2009，52，2： | 5 |
| 16 | Biochemical characters and antibiotic susceptibility of Staphylococcus aureus isolates显示文摘Objective:To observe the biochemical characters and antibiotic susceptibility of isolated Staphylococcia aureus(S.auerus) strains against some conventional and traditional antibiotics. Methods:Thirty post operative pathogenic isolated S.aureus strains were used in this study. Bacterial culture was done in Mueller-Hinton broth at 37 ℃.Characters of these strains were determined by traditional biochemical tests such as hydrolysis test of gelatin,urea,galactose, starch and protein,and fermentation of lactose and sucrose.Antibiotic susceptibility were carried out by minimum inhibilory concentration test,minium bactericidal concentration test,disc agar diffusion test and brain heart infusion oxacillin screening agar.Results:Prom this study,it was observed that 100%S.aureus isolates showed positive results in gelatin,urea and galactose hydrolysis test.50%isolates were positive in starch hydrolysis test,35%in protein hydrolysis test. 100%isolates in lactose fermenting test,but no isolate was positive in sucrose fermenting test. Antibiotic susceptibility testing suggested that 20%of isolates were resistant to kanamycin and 46.67%were resistant to oxacillin.Conclusions:These findings show that all these isolates have gelatin,urea,galactose hydrolysis and lactose fermenting activity.20%of these isolates were resistant to kanamvcin and 46.67%were resistant to oxacillin. | Subhankari Prasad Chakraborty Santanu Kar Mahapatra Somenath Roy | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，3： | 5 |
| 17 | The construction of orthodox super rpp semigroups显示文摘We define orthodox super rpp semigroups and study their semilattice decompositions. Standard representation theorem of orthodox super rpp semigroups whose subband of idempotents is in the varieties of bands described by an identity with at most three variables are obtained. | He Yong Guo Yuqi Kar Ping Shum | 2004 | Science China Mathematics2004，47，4： | 5 |
| 18 | Short term outcomes of minimally invasive selective lateral pelvic lymph node dissection for low rectal cancer显示文摘BACKGROUND Pelvic recurrence after rectal cancer surgery is still a significant problem despite the introduction of total mesorectal excision and chemoradiation treatment(CRT),and one of the most common areas of recurrence is in the lateral pelvic lymph nodes.Hence,there is a possible role for lateral pelvic lymph node dissection(LPND)in rectal cancer.AIM To evaluate the short-term outcomes of patients who underwent minimally invasive LPND during rectal cancer surgery.Secondary outcomes were to evaluate for any predictive factors to determine lymph node metastases based on pre-operative scans.METHODS From October 2016 to November 2019,22 patients with stage II or III rectal cancer underwent minimally invasive rectal cancer surgery and LPND.These patients were all discussed at a multidisciplinary tumor board meeting and most of them received neoadjuvant chemoradiation prior to surgery.All patients had radiologically positive lateral pelvic lymph nodes on the initial staging scans,defined as lymph nodes larger than 7 mm in long axis measurement,or abnormal radiological morphology.LPND was only performed on the involved side.RESULTS Majority of the patients were male(18/22,81.8%),with a median age of 65 years(44-81).Eighteen patients completed neoadjuvant CRT pre-operatively.18 patients(81.8%)had unilateral LPND,with the others receiving bilateral surgery.The median number of lateral pelvic lymph nodes harvested was 10(3-22)per pelvic side wall.8 patients(36.4%)had positive metastases identified in the lymph nodes harvested.The median pre-CRT size of these positive lymph nodes was 10 mm.Median length of stay was 7.5 d(3-76),and only 2 patients failed initial removal of their urinary catheter.Complication rates were low,with only 1 lymphocele and 1 anastomotic leak.There was only 1 mortality(4.5%).There have been no recurrences so far.CONCLUSION Chemoradiation is inadequate in completely eradicating lateral wall metastasis and there are still technical limitations in accurately diagnosing metastases in these areas.A pre-CRT lymph node size of≥10 mm is suggestive of metastases.LPND may be performed safely with minimally invasive surgery. | Kar Yong Wong Aloysius MN Tan | 2020 | World Journal of Gastrointestinal Surgery2020，12，4： | 4 |
| 19 | 太赫兹新型探测器的研究进展及应用显示文摘太赫兹波由于其独特的光学和电学性质,在物理学、生物学、公共安全检查、局域通信、信息安全、环境监测、无损检测和国防科技等民用或军事领域都有着广阔的应用前景。太赫兹探测器作为太赫兹领域的核心器件,在太赫兹系统中扮演着重要角色。因此太赫兹探测器的性能,决定了太赫兹系统的应用市场。近年来,太赫兹探测器的发展已取得突破性的成果,但是太赫兹探测器还存在着一些普遍的问题,制冷的太赫兹探测器虽然有响应速率快和噪声等效功率低等优点,但是其紧凑性不好,并且成本较高。室温可工作的太赫兹探测器虽然不需要制冷环境,但是噪声等效功率偏大,灵敏度也不高。该综述从太赫兹探测器的制备材料和器件形式等方面,阐述了太赫兹探测器的发展现状及其应用领域。 | 张玉平 唐利斌 刘玉菲 Kar Seng Teng 吴刚 胡伟达 韩福忠 | 2020 | 红外与毫米波学报2020，39，2： | 4 |
| 20 | Nitric oxide mediated Staphylococcus aureus pathogenesis and protective role of nanoconjugated vancomycin显示文摘Objective:To investigate the relation between fruit seeds,plants residuals and appendicitis. Methods:Among cases that underwent appendectomy,the appendicitis cases having fruit seeds and undigested plant residuals in their etiology were examined retrospectively.Also, histopathological features,age,sex,and parameters of morbidity and mortality were used. Results:Fruit seed was found in one case(0.05%) with presence of pus in appendix lumen, undigested plant residuals in 7 cases(0.35%).It was determined that there were appendix inflammation in 2 of the plant residuals cases,while there were obstruction and lymphoid hyperplasia in the appendix lumen of 5 cases.No mortality was observed.Conclusions:The ratio of acute appendicitis caused by plants is minimal among all appendectomised patients, but avoidence of eating undigested fruit seeds and chewing plants well may help to prevent appendicitis. | Subhankari Prasad Chakraborty Santanu Kar Mahapatra Sumanta Kumar Sahu Sourav Chattopadhyay Panchanan Pramanik Somenath Roy | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 4 |
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