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| 1 | 单开门椎管成形术与全椎板减压融合内固定术治疗脊髓型颈椎病的临床疗效比较显示文摘目的探讨颈后路单开门椎管成形术与全椎板减压侧块螺钉植骨融合内固定术治疗脊髓型颈椎病的临床疗效。方法 2006年9月-2009年9月,对143例多节段(≥3个)脊髓型颈椎病患者分别采用颈后路单开门扩大椎管成形术(A组,87例)及全椎板减压侧块螺钉植骨融合内固定术(B组,56例)治疗,两组患者性别、年龄、病程、病变分型、病变节段等一般资料比较差异均无统计学意义(P>0.05),具有可比性。随访观察并比较两组患者手术时间、术中出血量、术后神经功能恢复[采用日本骨科协会(JOA)17分评分法]及手术并发症发生情况,并对两组患者手术前后颈椎曲率指数(cervical curvature index,CCI)、颈椎活动度(range of motion,ROM)及颈肩部疼痛[采用疼痛视觉模拟评分(VAS)及颈椎功能障碍指数量表(NDI)评分]等指标进行评估。结果两组患者手术时间和术中出血量比较差异均无统计学意义(P>0.05)。两组患者均获随访,随访时间18~30个月,平均24个月。A、B组术后分别有4例(4.60%)和5例(8.93%)出现C5神经根麻痹症状,比较差异无统计学意义(χ2=0.475,P=0.482)。两组术后均无深部感染、假关节形成及螺钉松动需再手术等并发症发生。A组患者术后均无椎板再关门发生;B组患者末次随访时无螺钉脱出、断裂及继发神经损伤等发生。末次随访时A、B组分别有35例(40.23%)和11例(19.64%)有颈部轴性症状,比较差异有统计学意义(χ2=6.612,P=0.009)。两组患者术前JOA评分、CCI、颈椎ROM及VAS评分比较差异均无统计学意义(P>0.05);末次随访时两组JOA评分、颈椎ROM、VAS评分及A组CCI均较术前有显著改善(P<0.05)。末次随访时,A、B组间JOA评分及改善率、VAS评分比较差异均无统计学意义(P>0.05);A组ROM大于B组,CCI小于B组,差异有统计学意义(P<0.05);末次随访时NDI评分,A组在疼痛程度、上举能力、工作、驾车、反应及总分方面均显著优于B组(P<0.05)。结论两种手术方式在术后神经功能改善率上无明显差异,全椎板减压植骨融合内固定术能有效缓解术前疼痛,但颈椎活动度降低较大;单开门椎管成形术并发症较少,近期疗效满意。 | 张杭 孙天威 卢守亮 李清江 Sandip Kumar Yadav | 2012 | 中国修复重建外科杂志2012，26，10： | 13 |
| 2 | Enhanced myocardial fluorodeoxyglucose uptake following Adriamycin-based therapy: Evidence of early chemotherapeutic cardiotoxicity?显示文摘AIM: To analyze changes in myocardial glucose metabolism using fluorodeoxyglucose (FDG)-positron emission tomography (PET) in patients treated with adriamycin and to investigate the clinical significance of these changes.METHODS: Considering that FDG-PET scanning has the ability to show changes in glucose metabolism in the myocardium, we retrospectively analyzed the FDGPET studies of 18 lymphoma patients treated with adriamycin-based chemotherapy in both the preand posttherapy setting. Cardiac contractile parameters such as left ventricular ejection fraction were not available for correlation in all patients due to the short duration and the level of cumulative dose administered in these patients during the time of the follow-up FDG-PET study. The change in myocardial glucose utilization was estimated by change in standard uptake values (SUV) in the myocardium.RESULTS: We observed a significant change in SUVmean values in the myocardium (defined as more than change in cardiac SUVmean between pre-and post-chemotherapy PET) in 1 patients, whereas 6 patients did not show any significant cardiac FDG uptake in both preand post-therapy PET scans. Patients were divided into three groups based on the changes observed in myocardial tracer uptake on the followup 18 F-FDG-PET study. Group A (n = 8): showed an increase in cardiac 18 F-FDG uptake in the post-therapy scan compared to the baseline scan carried out prior to starting adriamycin-based chemotherapy. Group B (n = 6): showed no significant cardiac 18 F-FDG uptake in post-therapy and baseline PET scans, and group C (n = 4): showed a fall in cardiac 18 F-FDG uptake in the posttherapy scan compared to the baseline scan. Mean cumulative adriamycin dose (in mg/m 2 ) received during the time of the follow-up FDG-PET study was 256. 25, 250 and 137.5, respectively.CONCLUSION: Our study shows three different trends in the change in myocardial glucose metabolism in patients undergoing adriamycin-based chemotherapy. A further prospective study with prolonged follow-up of ventricular function is warranted to explore the significance of enhanced FDG uptake as a marker of early identification of adriamycin-induced cardiotoxicity. | Chaitanya Borde Purushottam Kand Sandip Basu | 2012 | World Journal of Radiology2012，4，5： | 9 |
| 3 | Removal efficiency of fluoride by novel Mg-Cr-Cl layered double hydroxide by batch process from water显示文摘The fluoride ion removal from aqueous solution using synthesized Mg-Cr-Cl layered double hydroxide has been reported.Mg-Cr-Cl was characterized by X-ray powder diffraction,Fourier-transform infrared,thermo-gravimetric analysis,differential thermal analysis,and scanning electron microscope.Adsorption experiments were carried out in batch mode as a function of adsorption dosages,contact time,pH,and initial fluoride concentration to get optimum adsorption capacity.The adsorption kinetic study showed that the adsorption process followed first order kinetics.The fluoride removal was 88.5% and 77.4% at pH 7 with an adsorbent dose of 0.6 g/100 mL solution and initial fluoride concentration of 10 mg/L and 100 mg/L,respectively.The equilibrium was established at 40 min.Adsorption experiment data were fitted well with Langmuir isotherm with R 2 = 0.9924.Thermodynamic constants were also measured and concluded that the adsorption process was spontaneous and endothermic in nature.The removal percentage decreased slowly with increasing pH.This process is suitable for industrial effluents.The regeneration of the material is not possible. | Sandip Mandal Swagatika Tripathy Tapswani Padhi Manoj Kumar Sahu Raj Kishore Patel | 2013 | Journal of Environmental Sciences2013，25，5： | 7 |
| 4 | Synthesis of bis(indolyl) methanes using aluminiumoxide(acidic) in dry media显示文摘Heterogeneous catalyst aluminium oxide(acidic) is found to be an effective catalyst for the solvent-free condensation reaction of indole with aldehydes in microwave irradiation with shorter reaction time and higher yields. | Sandip A.Sadaphal Amol H.Kategaonkar Vilas B.Labade Murlidhar S.Shingare | 2010 | Chinese Chemical Letters2010，21，1： | 7 |
| 5 | Chronic inhibition of cyclic guanosine monophosphate-specific phosphodiesterase 5 prevented cardiac fibrosis through inhibi- tion of transforming growth factor 13-induced Smad signaling显示文摘 | Wei Gong* Mengwen Yan Junxiong Chen Sandip Chaugai Chen Chen Daowen Wang | 2014 | Frontiers of Medicine2014，8，4： | 6 |
| 6 | 钛板表面激光熔覆锆基合金涂层的组织结构显示文摘 利用激光熔覆技术在Ti板上制备了非晶复合涂层,利用X射线衍射仪、能谱仪、扫描电镜和透射电子显微镜对熔覆层和结合区的组织结构进行了表征。研究发现,熔覆层组织主要由非晶、Zr的金属间化合物、氧化物及局部纳米晶组成。基体与熔覆层结合区由Ti的柱状晶和α(Ti/Zr)固溶体所构成,保证了基体与熔覆层之间有良好的冶金结合。 | 王彦芳 刘忆 李刚 王存山 夏元良 董闯 Sandip Bysakh | 2003 | 复合材料学报2003，20，3： | 6 |
| 7 | Hepatitis C virus infection and insulin resistance显示文摘Approximately 170 million people worldwide are chronically infected with hepatitis C virus(HCV).Chronic HCV infection is the leading cause for the development of liver fibrosis,cirrhosis,hepatocellular carcinoma(HCC)and is the primary cause for liver transplantation in the western world.Insulin resistance is one of the pathological features in patients with HCV infection and often leads to development of typeⅡdiabetes.Insulin resistance plays an important role in the development of various complications associated with HCV infection.Recent evidence indicates that HCV associated insulin resistance may result in hepatic fibrosis,steatosis,HCC and resistance to anti-viral treatment.Thus,HCV associated insulin resistance is a therapeutic target at any stage of HCV infection.HCV modulates normal cellular gene expression and interferes with the insulin signaling pathway.Various mechanisms have been proposed in regard to HCV mediated insulin resistance,involving up regulation of inflammatory cytokines,like tumor necrosis factor-α,phosphorylation of insulin-receptor substrate-1,Akt,up-regulation of gluconeogenic genes like glucose 6 phosphatase,phosphoenolpyruvate carboxykinase 2,and accumulation of lipid droplets.In this review,we summarize the available information on how HCV infection interferes with insulin signaling pathways resulting in insulin resistance. | Sandip K Bose Ranjit Ray | 2014 | World Journal of Diabetes2014，5，1： | 6 |
| 8 | Psoas muscle metastasis from cervical carcinoma:Correlation and comparison of diagnostic features on FDG-PET/CT and diffusion-weighted MRI显示文摘Psoas muscle metastasis, though rare, is the commonest site of skeletal muscle involvement in cervical carcinoma. The appropriate clinical management of this condition, particularly of the pain related to malignant psoas syndrome, is still evolving and the diagnostic features on conventional morphological imaging modalities are often non specific, with the differential diagnosis lying between sarcoma, hematoma, and abscess. In this report, a comparison of various morphofunctional imaging modalities was made. Fluorodeoxyglucosepositron emission tomography(FDG-PET)/computed tomography(CT) was the first to suspect disease involvement of the psoas muscle, demonstrating intense FDG uptake(compared with the contralateral muscle), while ultrasound showed heterogeneous echotexture, and magnetic resonance imaging(MRI) showed subtle altered signal intensity in the right psoas muscle. Both anatomical imaging modalities and non contrast CT of the PET-CT examination demonstrated a bulky psoas muscle, without any focal abnormality. On diffusionweighted imaging of MRI(DWI-MRI), restricted diffusion of the involved muscle was an important observation. The psoas muscle metastatic involvement was proven histopathologically. Thus, enhanced glucose metabolism and restricted diffusion in the newer noninvasive molecular imaging modalities(e.g., PET/CT and DWI-MRI) could serve as valuable adjunctive parameters in diagnosing this entity in the absence of a focal abnormality in the anatomical modalities. In the treatment response monitoring scenario, FDG-PET/CT demonstrated near complete resolution following administration of 3 cycles of systemic chemotherapy and local external radiotherapy. | Sandip Basu Abhishek Mahajan | 2014 | World Journal of Radiology2014，6，4： | 6 |
| 9 | Greener approach towards the facile synthesis of 1,4-dihydropyrano[2,3-c]pyrazol-5-y1 cyanide derivatives at room temperature显示文摘这份报告描述离子的液体催化的 triethylammonium 醋酸盐(TEAA ) 6-amino-4-aryl-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano 的一壶合成[2,3-c ] 由在房间温度的芳香的醛, malononitrile 和 3-methyl-1-phenyl-2-pyrazolin-5-one 的反应的 pyrazoles。TEAA 作为反应媒介和催化剂起双作用。它能容易也在几被恢复并且再使用跑。TEAA 提供更绿的反应协议介绍排除的方法论器官的溶剂的需要,昂贵、有毒的催化剂。 | Ravi S.Balaskar Sandip N.Gavade Madhav S.Mane Bapurao B.Shingate Murlidhar S.Shingare Dhananjay V.Mane | 2010 | Chinese Chemical Letters2010，21，10： | 5 |
| 10 | Potential of (18)~F-FDG-PET as a valuable adjunct to clinical and response assessment in rheumatoid arthritis and seronegative spondyloarthropathies显示文摘AIM: To evaluate the role of fluorine-18-labeled fluorodeoxyglucose positron emission tomography (18F-FDG PET) in various rheumatic diseases and its potential in the early assessment of treatment response in a limited number of patients. METHODS: This study involved 28 newly diagnosed patients, of these 17 had rheumatoid arthritis (RA) and 11 had seronegative spondyloarthropathy (SSA). In the SSA group, 7 patients had ankylosing spondylitis, 3 had psoriatic arthritis, and one had non-specific SSA. Patients with RA were selected as per the American College of Rheumatology criteria. One hour after FDG injection, a whole body PET scan was performed from the skull vertex to below the knee joints using a GE Advance dedicated PET scanner. Separate scans were acquired for both upper and lower limbs. Post-treatment scans were performed in 9 patients in the RA group (at 6-9 wk from baseline) and in 1 patient with psoriatic arthropathy. The pattern of FDG uptake was analysed visually and quantified as maximum standardized uptake value (SUVmax) in a standard region of interest. Metabolic response on the scan was assessed qualitatively and quantitatively and was correlated with clinical assessment. RESULTS: The qualitative FDG uptake was in agreement with the clinically involved joints, erythrocyte sedimentation rate, C-reactive protein values and the clinical assessment by the rheumatologist. All 17 patients in the RA group showed the highest FDG avidity in painful/swollen/tender joints. The uptake pattern was homogeneous, intense and poly-articular in distribution. Hypermetabolism in the regional nodes (axillary nodes in the case of upper limb joint involvement and inguinal nodes in lower limb joints) was a constant feature in patients with RA. Multiple other extra-articular lesions were also observed including thyroid glands (in associated thyroiditis) and in the subcutaneous nodules. Treatment response was better appreciated using SUVmax values than visual interpretation, when compared with clinical evaluation. Four patients showed a favourable response, while 3 had stable disease and 2 showed disease progression. The resolution of regional nodal uptake (axillary or inguinal nodes based on site of joint involvement) in RA following disease modifying anti-rheumatoid drugs was noteworthy, which could be regarded as an additional parameter for identifying responding patients. In the SSA group, uptake in the affected joint was heterogeneous, low grade and nonsymmetrical. In particular, there was intense tendon and muscular uptake corresponding to symptomatic joints. The patients with psoriatic arthritis showed intense FDG uptake in the joints and soft tissue. CONCLUSION: 18F-FDG PET accurately delineates the ongoing inflammatory activity in various rheumatic diseases (both at articular and extra-articular sites) and relates well to clinical symptoms. Different metabolic patterns on FDG-PET scanning in RA and SSA can have important implications for their diagnosis and management in the future with the support of larger studies. FDG-PET molecular imaging is also a sensitive tool in the early assessment of treatment response, especially when using quantitative information. With these benefits, FDG-PET could play a pivotal clinical role in the management of inflammatory joint disorders in the future. | Vishu Vijayant Manjit Sarma Hrushikesh Aurangabadkar Lata Bichile Sandip Basu | 2012 | World Journal of Radiology2012，4，12： | 5 |
| 11 | Anti-endothelial cell antibody rich sera from rheumatic heart disease patients induces proinflammatory phenotype and methylation alteration in endothelial cells显示文摘Rheumatic heart disease(RHD)is a major cause of cardiovascular morbidity and mortality in developing nations like India.RHD commonly affects the mitral valve which is lined by a single layer of endothelial cells(ECs).The role of ECs in mitral valve damage during RHD is not well elucidated.In here,anti-endothelial cell antibody from RHD patients has been used to stimulate the ECs(HUVECs and HMVECs).ECs proinflammatory phenotype with increased expression of TNFa,IL-6,IL-8,IFNg,IL-1b,ICAM1,VCAM1,E-selectin,laminin B,and vimentin was documented in both ECs.The promoter hypomethylation of various key inflammatory cytokines(TNFa,IL-6,and IL-8),integrin(ICAM1)associated with leukocyte transendothelial migration,and extracellular matrix genes(vimentin,and laminin)were also observed.Further,the in-vitro data was in accordance with ex-vivo observations which correlated significantly with the etiological factors such as smoking,socioeconomic status,and housing.Thus,the study sheds light on the role of ECs in RHD which is a step forward in the elucidation of disease pathogenesis. | Mukul Rastogi Subendu Sarkar Ankita Makol Rana Sandip Singh Uma Nahar Saikia Dibyajyoti Banerjee Seema Chopra Anuradha Chakraborti | 2018 | Genes & Diseases2018，5，3： | 5 |
| 12 | Effects of Meridional Sea Surface Temperature Changes on Stratospheric Temperature and Circulation显示文摘Using a state-of-the-art chemistry-climate model, we analyzed the atmospheric responses to increases in sea surface temperature(SST). The results showed that increases in SST and the SST meridional gradient could intensify the subtropical westerly jets and significantly weaken the northern polar vortex. In the model runs, global uniform SST increases produced a more significant impact on the southern stratosphere than the northern stratosphere, while SST gradient increases produced a more significant impact on the northern stratosphere. The asymmetric responses of the northern and southern polar stratosphere to SST meridional gradient changes were found to be mainly due to different wave properties and transmissions in the northern and southern atmosphere. Although SST increases may give rise to stronger waves, the results showed that the effect of SST increases on the vertical propagation of tropospheric waves into the stratosphere will vary with height and latitude and be sensitive to SST meridional gradient changes. Both uniform and non-uniform SST increases accelerated the large-scale Brewer–Dobson circulation(BDC), but the gradient increases of SST between 60°S and 60°N resulted in younger mean age-of-air in the stratosphere and a larger increase in tropical upwelling, with a much higher tropopause than from a global uniform 1.0 K SST increase. | HU Dingzhu TIAN Wenshou XIE Fei SHU Jianchuan Sandip DHOMSE | 2014 | Advances in Atmospheric Sciences2014，31，4： | 5 |
| 13 | Effect of ultrasonic vibration-assisted laser surface melting and texturing of Ti-6Al-4V ELI alloy on surface properties显示文摘Ultrasonic vibration-assisted laser surface processing that involves application of vertical ultrasonic vibrations to the Ti-6 Al-4 V alloy substrates while being irradiated with a CO_2 laser was performed for the development of laser melted and textured surfaces with potential applications in biomedical implants.The laser processing resulted in very consistent repeating undulating grooved surfaces, and the undulations were significantly more pronounced in the samples processed with higher ultrasonic power outputs.The phase evolution, studied by x-ray diffraction, confirmed that the laser processing triggered transformation of globular α→ acicular α and martensitic α' as well as increased amounts of retained α phases,which were also reflected in the microscopic analysis. The surface texture developed by laser processing resulted in increased surface wettability with increasing ultrasonic power output. The textured surfaces exhibited marked decrease in coefficients of friction during sliding wear testing performed under simulated body fluid due to lubricant entrainment within the textured grooves. The texturing also resulted in significant reduction in surface contact area during the wear process, which considerably reduced the overall wear rates due to abrasive wear. | Sourabh Biswas S.Habib Alavi Bhishma Sedai Frank D.Blum Sandip P.Harimkar | 2019 | Journal of Materials Science & Technology2019，35，2： | 5 |
| 14 | 胸椎黄韧带骨化合并后纵韧带骨化行单纯后路减压治疗的预后影响因素分析显示文摘目的研究胸椎黄韧带骨化症(OLF)合并后纵韧带骨化(OPLL)采用单纯后路减压手术治疗的预后影响因素。方法对2006年1月至2010年6月经手术治疗且完整随访的83例胸椎OLF合并OPLL患者资料进行回顾性分析,对可能影响患者预后的因素,如性别、年龄、病程、术前及术后日本骨科协会(JOA)评分、病变节段、胸椎OPLL骨化类型、胸椎后凸角度、前方胸椎OPLL程度、胸椎OLF减压节段数、术前是否存在二便功能障碍、术后是否存在脑脊液漏及是否合并颈腰椎疾患等因素进行)(χ2检验和Logistic回归统计分析。结果根据术后JOA评分改善率分为优良组(58例)和不良组(25例),两组间年龄、术前JOA评分及病程等患者一般资料无统计学意义(P〉0.05)。在病变节段(χ2=6.290,P=0.043)、OPLL骨化类型(χ2=5.361,P=0.021)和术前存在二便功能障碍(χ2=27.711,P=0.000)等方面差异具有统计学意义;Logistic回归分析发现病变位于上段胸椎(P=0.044)、OPLL鸟嘴型(P=0.023)及术前存在二便功能障碍(P=0.009)与预后影响关系密切。术后24例(28.9%)患者出现脑脊液漏,3例患者术后早期出现深部感染,2例患者术后神经功能恶化。结论上胸段骨化症预后较好,但存在鸟嘴型OPLL、术前存在二便功能障碍的患者预后不良,跳跃性多节段骨化症及合并重度颈腰椎疾患是预后不良的影响因素。 | 孙天威 张黎龙 张杭 卢守亮 Sandip Kumar Yadav | 2012 | 中华外科杂志2012，50，12： | 4 |
| 15 | Property mapping of polycrystalline diamond coatings over large area显示文摘Large-area polycrystalline diamond(PCD)coatings are important for fields such as thermal management,optical windows,tribological moving mechanical assemblies,harsh chemical environments,biological sensors,etc.Microwave plasma chemical vapor deposition(MPCVD)is a standard technique to grow high-quality PCD films over large area due to the absence of contact between the reactive species and the filament or the chamber wall.However,the existence of temperature gradients during growth may compromise the desired uniformity of the final diamond coatings.In the present work,a thick PCD coating was deposited on a 100-mm silicon substrate inside a 915-MHz reactor;the temperature gradient resulted in a non-uniform diamond coating.An attempt was made to relate the local temperature variation during deposition and the different properties of the final coating.It was found that there was large instability inside the system,in terms of substrate temperature(as high asΔT=212℃),that resulted in a large dispersion of the diamond coating’s final properties:residual stress(-15.8 GPa to+6.2 GPa),surface morphology(octahedral pyramids with(111)planes to cubo-octahedrals with(100)flat top surfaces),thickness(190μm to 245μm),columnar growth of diamond(with appearance of variety of nanostructures),nucleation side hardness(17 GPa to 48 GPa),quality(Raman peak FWHM varying from 5.1 cm^(-1) to 12.4 cm^(-1) with occasional splitting).This random variation in properties over large-area PCD coating may hamper reproducible diamond growth for any meaningful technological application. | Awadesh Kumar MALLIK Sandip BYSAKH Monjoy SREEMANY Sudakshina ROY Jiten GHOSH Soumyendu ROY Joana Catarina MENDES Jose GRACIO Someswar DATTA | 2014 | Journal of Advanced Ceramics2014，3，1： | 4 |
| 16 | 纳米Ce_1Mg_xZr_(1-x)O_2固体多相催化剂的制备、表征及催化合成四氢苯并[b]吡喃衍生物的性能(英文)显示文摘A series of Ce1MgxZr1-xO2 mixed metal oxides with different molar ratios were prepared by simple co-precipitation and were characterized by X-ray diffraction,infrared spectroscopy,scanning electron microscopy,energy dispersive spectroscopy,temperature-programmed desorption of CO2,and N2 adsorption techniques.The prepared materials were tested for catalytic activity by the synthesis of tetrahydrobenzo[b]pyran derivatives using a three component reaction(aromatic aldehydes,malononitrile,and dimedone) in an ethanol medium.The best catalytic activity was obtained with Ce1Mg0.6Zr0.4O2.The particle size or crystallite size was estimated using the Debye-Scherrer equation.The addition of magnesium oxide into the ceria-zirconia lattice resulted in the formation of nanosized particles ranging from 5.41 to 9.78 nm.This work describes the catalytic behavior of magnesium oxide in mixed metal oxide systems. | Sandip RATHOD Balasaheb ARBAD Machhindra LANDE | 2010 | 催化学报2010，31，6： | 3 |
| 17 | 尼泊尔喜马拉雅地区塔玛科什3级水电工程--穿越软弱构造片岩修建隧洞所面临的挑战显示文摘由于尼泊尔喜马拉雅地区岩石强度较低,水平应力较高,因此在该软弱构造片岩带中开挖隧洞具有较大的挑战性。文章主要阐述装机容量为650 kW的塔玛科什3级水电工程17km长大跨度隧洞和大型地下发电厂房(这两项工程计划穿越夹杂有软弱构造片岩带的坚硬眼球状片麻岩区域)所面临的重大技术挑战。穿过片岩带开挖的隧洞长度约占总长的15%,由于此岩层带岩石强度较低,具有剪切特性和渗流现象,且水平应力较高,围岩挤压和隧洞塌方都是可预期的问题,因此该工程地下开挖主要关注的问题是大尺寸隧洞的可施工性和工期。为了解决可预期问题,进行了更进一步的研究,主要集中在隧洞最大可建尺寸、方位、减少围岩挤压的开挖方法,以及地下发电厂房稳定性和合理岩石支护设计上。研究发现,在构造片岩带中可施工的全断面隧洞最大尺寸可达9m,为改进的马蹄形(有弧形仰拱)。通过对隧洞三种不同方位方案(即正交、斜交、平行)的分析发现,与叶理面正交的方案最佳,可减少围岩挤压近50%。 | Subas Chandra Sunuwar Sandip Shah Ashish Subedi Muna Sharma | 2013 | 现代隧道技术2013，50，1： | 3 |
| 18 | BMP与后纵韧带骨化症易患性的研究进展显示文摘目的综述BMP与后纵韧带骨化症(ossification of the posterior longitudinal ligament,OPLL)易患性的研究进展。方法查阅近年国内外有关BMP与OPLL易患性的相关参考文献并进行总结。结果 BMP基因的单核苷酸多态性(single nucleotide polymorphisms,SNPs)产生微效累加效应增加对OPLL的易感性,多种环境因素可通过增加BMPs基因的表达,促进OPLL的发生、发展。结论 BMPs易感基因的SNPs可促进个体对OPLL的易感性,SNPs的累加效应及与环境因素的相互作用则可影响个体对OPLL易患性的高低。 | 方钊 孙天威 Sandip Kumar Yadav | 2012 | 中国修复重建外科杂志2012，26，10： | 3 |
| 19 | 在L-缬氨酸介质中应用聚二苯并-18-冠醚-6分离铈(Ⅲ)(英文)显示文摘A column chromatographic method has been developed for the separation and determination of cerium(Ⅲ) using poly[dibenzo-18-crown-6].The separation was carried out in L-valine medium.The adsorption of cerium(Ⅲ) was quantitative from 1×10-1 to 1×10-4 mol/L L-valine.Amongst the various eluents,1.0-8.0 mol/L hydrochloric acid,1.0-8.0 mol/L hydrobromic acid,1.0-8.0 mol/L perchloric acid,1.0-2.0 mol/L sulfuric acid and 4.0-5.0 mol/L acetic acid,were found to be the efficient eluents for cerium(Ⅲ).The capacity of poly[dibenzo-18-crown-6] for cerium(Ⅲ) was(0.428±0.01) mmol/g.The method was applied to the separation of cerium(Ⅲ) from associated elements link uranium(Ⅵ) and thorium(Ⅳ).It was also applied for the determination of cerium(Ⅲ) in geological samples.The method is simple,rapid and selective with good reproducibility(approximately±2%). | SABALE Sandip R MOHITE Baburao S | 2009 | 色谱2009，27，2： | 3 |
| 20 | Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation显示文摘导致消炎痛的胃的溃疡在试验性的老鼠模型由 ellagic 酸(EA ) 愈合的机制在我们的学习被描述。溃疡索引(UI ) 和 myeloperoxidase (军邮局) 胃纸巾的活动在消炎痛以后在第三天显示出最大的溃疡(18 mg/kg,单个剂量) 管理。UI 和军邮局活动的初步的观察建议 EA 拥有愈合溃疡的活动。另外的反溃疡参数象前列腺素 E2 的层次那样, cyclooxygenase (艇长) 1 和 2 酶,反煽动性的 cytokines [ interleukin ( IL ) -4 和-5], pro-angiogenic 因素例如脉管的 endothelial 生长因素, hepatocyte 生长因素( HGF ),并且 endothelial 生长因素( EGF )由消炎痛是下面调整的。为 3 天的处理转移了的 EA (7 mg/kg/day ) 导致消炎痛的支持 inflammatory 愈合的生物化学的参数站在一起。这些活动与 EA 的能力被相关改变愈合的 COX-2-dependent 小径。然而, EA 的愈合溃疡的活动被特定的 COX-2 禁止者, celecoxib,和 NS-398 的管理前损害。一起拿,这些结果建议 EA 处理加速溃疡由导致 IL-4 愈合, EGF/HGF 铺平并且提高 COX-2 表示。 | Ananya Chatterjee Sirshendu Chatterjee Smita Das Arpita Saha Subrata Chattopadhyay Sandip K.Bandyopadhyay | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 3 |
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