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| 1 | Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells显示文摘基础切除修理(BER ) 是为由消除损坏的几打维持 genomic 完整的 evolutionarily 保存的进程(氧化或烷基 ated ) 或内长地被产生或由 genotoxicants 导致了的不恰当的库,主要反应的氧种类(ROS ) 。BER 包含由脱氧核糖核酸 glycosylase 以基础切除开始的 4-5 步骤,由通常包含 AP-endonuclease (无尾猿) 产生 3' 的一条普通小径列在后面哦在损坏地点的终点,与由脱氧核糖核酸连接酶封上的 DNA 和刻痕由修复合成列在后面。这条小径也负责修理脱氧核糖核酸单个海滨与 ROS 直接产生的堵住的终点决裂。将近所有 glycosylases,比他们特别地为氧化的底的底层损害少得多,宽广、重叠的底层变化,并且能用作备份酶体内。相反,哺乳动物的房间编码仅仅一无尾猿, APE1,不同于在更低的有机体的二无尾猿。尽管有全面类似,有在哺乳动物的不同潜水艇小径的 BER 比在 E 更复杂。关口 i。glycosylases 与下游的蛋白质形成建筑群经由不同潜水艇小径执行有效修理哪个之一,负责因为海滨的修理与 NEIL 家庭 glycosylases 或由 ROS 产生的 3' 磷酸盐终点决裂,要求多核苷酸 kinase 的磷酸酶活动而不是 APE1。不同建筑群可以利用不同 DNA 和 ligases。哺乳动物的 glycosylases 非在终点之一保存了延期、为酶的活动非必需却为和另外的 BER 并且非的相互作用需要 -- 为指向的复杂形成和细胞器的 BER 蛋白质。哺乳动物的酶 covalently 有时被修改它可以影响活动和复杂形成。这评论的焦点在在为氧化损坏的哺乳动物的 BER 的早步上。 | Muralidhar L Hegde Tapas K Hazra Sankar Mitra | 2008 | Cell Research2008，18，1： | 15 |
| 2 | Pre-treatment of rocks prior to comminution--A critical review of present practices显示文摘It has been an established fact that comminution processes, crushing and grinding, are most energy intensive processes which account for more than half of the total energy consumed in mineral industries.Various alternative pre-treatment methods have been tried by experts around the globe. Although these methods yielded positive results in terms of reduction in energy consumption in crushing and particularly, in grinding operations at laboratory scale, their industrial application still remains an unresolved issue and challenge. Present review paper describes each one of these methods along with outcome of earlier studies and issues that need to be addressed through further rigorous experimental investigation.It also suggests the direction in which future studies can be carried out to meet the primary objective of making comminution processes more energy efficient than today they are. | Somani Aditya Nandi Tapas K. Pal Samir K. Majumder Arun K. | 2017 | International Journal of Mining Science and Technology2017，27，2： | 7 |
| 3 | Damage and geological assessment of the 18 September 2011 M_w 6.9 earthquake in Sikkim,India using very high resolution satellite data显示文摘Post-disaster very high resolution(VHR) satellite data are potential sources to provide detailed information on damage and geological changes for a large area in a short time.In this paper,we studied landslides triggered by the M_w 6.9 earthquake in Sikkim,India which occurred on 18 September 2011 using VHR data from Cartosat-1,GeoEye-1,QuickBird-2 and WorldView-2 satellites.Since the earthquake-affected area is located in mostly inaccessible Himalayan terrain,VHR data from these satellites provided a unique opportunity for quick and synoptic assessment of the damage.Using visual change analysis technique through comparison of pre- and post-earthquake images,we assessed the damage caused by the event.A total of 123 images acquired from eight satellites,covering an area of4105 km2 were analysed and 1196 new landslides triggered by the earthquake were mapped.Road blockages and severely affected villages were also identified.Geological assessment of the terrain highlighted linear disposition of landslides along existing fault scarps,suggesting a reactivation of fault.The landslide inventory map prepared from VHR images also showed a good correlation with the earthquake shake map.Results showed that several parts of north Sikkim,particularly Mangan and Chungthang,which are close to the epicentre,were severely affected by the earthquake,and that the event-based landslide inventory map can be used in future earthquake-triggered landslide susceptibility assessment studies. | Tapas R.Martha K.Babu Govindharaj K.Vinod Kumar | 2015 | Geoscience Frontiers2015，6，6： | 6 |
| 4 | Abrus agglutinin suppresses human hepatocellular carcinoma in vitro and in vivo by inducing caspase- mediated cell death显示文摘 | Subhadip MUKHOPADHYAY Prashanta Kumar PANDA Durgesh Nandini DAS Niharika SINHA Birendra BEHERA Tapas Kumar MAITI Sujit Kumar BHUTIA | 2014 | Acta Pharmacologica Sinica2014，35，6： | 5 |
| 5 | Effect of pyroxenite and olivine minerals as source of MgO in hematite pellet on improvement of metallurgical properties显示文摘Pelletization of hematite ore requires high fineness and very high induration temperature(~1325 °C) owing to its poor diffusion bonding unlike magnetite ore. Further, high-alumina hematite pellets show very high reduction degradation index(RDI) during low temperature(500-650 °C) reduction due to their volume expansion and lattice distortion. Noamundi(India) hematite ore contains very high Al2O3(2.3%) with adverse ratio of alumina to silica(~2) for which, it shows very high RDI. In this work, the acid pellets prepared from Noamundi ore fines of optimum Blaine fineness show good cold crushing strength(CCS). However, it shows very high RDI(77%). In order to reduce RDI, Mg O in form of two different gangue-containing fluxes, such as pyroxenite and olivine in varying quantities has been added. The optimum requirement and performance of these fluxes has been examined and compared. Both pyroxenite and olivine fluxed pellets show significant lowering of RDI(26% and 23%, respectively) and improvement of other properties, viz CCS, swelling indices etc with good reducibility(70%-77%). Finally, a good quality acidic hematite pellet was developed from high-alumina ore without using any lime which is very important charge material in combination of basic sinter in blast furnace. | Jagannath Pal Satadal Ghorai Bikash Nandi Tapas Chakraborty Goutam Das T.Venugopalan | 2015 | Journal of Central South University2015，22，9： | 5 |
| 6 | A Novel Cascaded PID Controller for Automatic Generation Control Analysis With Renewable Sources显示文摘Present day power scenarios demand a high quality uninterrupted power supply and needs environmental issues to be addressed. Both concerns can be dealt with by the introduction of the renewable sources to the existing power system. Thus, automatic generation control(AGC) with diverse renewable sources and a modified-cascaded controller are presented in the paper.Also, a new hybrid scheme of the improved teaching learning based optimization-differential evolution(hITLBO-DE) algorithm is applied for providing optimization of controller parameters. A study of the system with a technique such as TLBO applied to a proportional integral derivative(PID), integral double derivative(IDD) and PIDD is compared to hITLBO-DE tuned cascaded controller with dynamic load change.The suggested methodology has been extensively applied to a 2-area system with a diverse source power system with various operation time non-linearities such as dead-band of, generation rate constraint and reheat thermal units. The multi-area system with reheat thermal plants, hydel plants and a unit of a wind-diesel combination is tested with the cascaded controller scheme with a different controller setting for each area. The variation of the load is taken within 1% to 5% of the connected load and robustness analysis is shown by modifying essential factors simultaneously by± 30%. Finally, the proposed scheme of controller and optimization technique is also tested with a 5-equal area thermal system with non-linearities. The simulation results demonstrate the superiority of the proposed controller and algorithm under a dynamically changing load. | Aurobindo Behera Tapas Kumar Panigrahi PrakashK·Ray Arun Kumar Sahoo | 2019 | IEEE/CAA Journal of Automatica Sinica2019，6，6： | 5 |
| 7 | Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers显示文摘OBJECTIVE Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma(HNSCC).In the present study,we investigated whether garcinol,apolyisoprenylated benzophenone can chemosensitize HNSCC to cisplatin.METHODS The effect of garcinol and cisplatin on HNSCC was assessed by MTT,Western blotting,real time PCR,FACS,immunohistochemistry,DNA binding assay and xenograft mouse model.RESULTS We found that garcinol inhibited the viability of a panel of diverse HNSCC cell lines,enhanced the apoptotic effect of cisplatin,suppressed constitutive as well as cisplatin-induced NF-κB activation,and downregulated the expression of various oncogenic gene products(cyclin D1,Bcl-2,survivin and VEGF).In vivo study showed that administration of garcinol alone(0.5 mg·kg-1,ip five times/week)significantly suppressed the growth of the tumor,and this effect was further increased by cisplatin.Both the markers of proliferation index(Ki-67)and microvessel density(CD31)were downregulated in tumor tissues by the combination of cisplatin and garcinol.The pharmacokinetic results of garcinol indicated that good systemic exposure was achievable after ip administration of garcinol at 0.5and 2mg·kg-1 with mean peak concentration(cmax)of 1825.4 and 6635.7nmol·L-1 in the mouse serum,respectively.CONCLUSION Overall,our results suggest that garcinol can indeed potentiate the effects of cisplatin by negative regulation of various inflammatory and proliferative biomarkers. | Feng Li Muthu K. Shanmugam Kodappully Sivaraman Siveen Fan Wang Tina H. Ong Ser Yue Loo Mahadeva M.M. Swamy Somnath Mandal Alan Prem Kumar Boon Cher Goh Tapas Kundu Kwang Seok Ahn Ling Zhi Wang Kam Man Hui Gautam Sethi | 2015 | 中国药理学与毒理学杂志2015，29，S1： | 4 |
| 8 | 亲水型功能化石墨烯的分散性及其对水泥基复合材料力学性能的影响显示文摘为了解决石墨烯纳米片在水泥基体中的分散问题,采用芳基重氮盐(F)对氧化石墨烯(GO)进行改性,制备了一种新型亲水型功能化石墨烯(FG)。结果表明,FG在水溶剂中最大的分散浓度能够达到2.1 mg/mL。FTIR、拉曼光谱和XPS结果表明F成功对石墨烯进行了表面改性。对比纯水泥基体材料,本文所制备的亲水型FG/水泥复合材料的28天抗折强度和抗压强度相对提高了95.3%和78.3%。F对GO进行改性,实现了石墨烯在水泥基材料中的均匀分散及对其力学性能的提升。 | 余东升 付芳 贾铁昆 李继利 TAPAS Kuila 骆雪 田新生 张慧军 周加左 刘君梦 龙巍云 陈欢 | 2021 | 复合材料学报2021，38，2： | 4 |
| 9 | An account of the strategies to enhance the water splitting efficiency of noble-metal-free electrocatalysts显示文摘The electrolysis of water for hydrogen generation has shown immense promise as an energy conversion technology for the green energy economy.Two concurrently occurring electrochemical reactions in water electrolysis(hydrogen and oxygen evolution reactions)are sluggish in nature and therefore the employment of electrocatalysts is highly essential.Noble-metal-based electrocatalysts(Pt,Ru O_(2),Ir O_(2),etc.)have shown superior activity towards these reactions.However,their lower natural abundance and inferior stability make the cost to performance ratio of water electrolysis too high.Thus,huge amount of research efforts are being carried out to develop electrocatalysts consisting of earth abundant elements(transition metals,carbon etc.)as the replacement of these noble-metal-based materials.Transition metal compounds,carbonaceous and hybrid materials have shown promise as efficient electrocatalysts but there is still huge gap between the activities of these materials and the noble-metal-based electrocatalysts.Several strategies like morphology modulation,elemental doping,defect engineering etc.are being deployed to enhance the activity of these noble-metal-free electrocatalysts.This review summarizes these strategies and thoroughly discusses the reason behind the changes in activity of the electrocatalysts owing to these modifications.Finally,the remaining research gaps and future prospects in this field are also discussed in detail. | Subhasis Shit Saikat Bolar Naresh Chandra Murmu Tapas Kuila | 2021 | Journal of Energy Chemistry2021，30，8： | 3 |
| 10 | Prediction of oil-water flow patterns, radial distribution of volume fraction, pressure and velocity during separated flows in horizontal pipe显示文摘Flow of two immiscible fluids gives rise to variety of flow patterns,which influence transportation process.In this work,we present detailed analysis on the prediction of flow pattern maps and radial distribution of volume fraction,pressure and velocity of a pair of immiscible liquids through a horizontal pipeline by computational fluid dynamics(CFD) simulation using ANSYS FLUENT 6.3.Moderately viscous oil and water have been taken as the fluid pair for study.Volume of fluid(VOF) method has been employed to predict various flow patterns by assuming unsteady flow,immiscible liquid pair,constant liquid properties,and co-axial flow.From the grid independent study,we have selected 47 037 number of quadrilateral mesh elements for the entire geometry.Simulation successfully predicts almost all the flow patterns(viz.,plug,slug,stratified wavy,stratified mixed and annular),except dispersion of oil in water and dispersion of water in oil.The simulated results are validated with experimental results of oil volume fraction and flow pattern map.Radial distribution of volume fraction,pressure and velocity profiles describe the nature of the stratified wavy,stratified mixed and annular flow pattern.These profiles help to developing the phenomenological correlations of interfacial characteristics in two-phase flow. | Anand B.DESAMALA Vinayak VIJAYAN Anjali DASARI Ashok Kumar DASMAHAPATRA Tapas K.MANDAL | 2016 | Journal of Hydrodynamics2016，28，4： | 3 |
| 11 | IL-15 temporally reorients IL-10 biased B-la cells toward I L- 12 expression显示文摘 | Amlan Kanti Ghosh Debolina Sinha Subhadeep Mukherjee Ratna Biswas Tapas Biswas | 2016 | Cellular & Molecular Immunology2016，13，2： | 3 |
| 12 | Effect of Rare Earth and Transition Metal Elements on the Glass Forming Ability of Mechanical Alloyed Al–TM–RE Based Amorphous Alloys显示文摘The present work aims to compare the amorphous phase forming ability of ternary and quaternary Al based alloys(Al86Ni8Y6, Al86Ni6Y6Co2, Al86Ni8La6 and Al86Ni8Y4.5La1.5) synthesized via mechanical alloying by varying the composition, i.e. fully or partially replacing rare earth(RE) and transition metal(TM) elements based on similar atomic radii and coordination number. X-ray diffraction and high resolution transmission electron microscopy study revealed that the amorphization process occurred through formation of various intermetallic phases and nanocrystalline FCC Al. Fully amorphous phase was obtained for the alloys not containing lanthanum, whereas the other alloys containing La showed partial amorphization with reappearance of intermetallic phases attributed to mechanical crystallization. Differential scanning calorimetry study confirmed better thermal stability with wider transformation temperature for the alloys without La. | Ram S.Maurya Tapas Laha | 2015 | Journal of Materials Science & Technology2015，31，11： | 3 |
| 13 | 键级和化合价的分子轨道理论显示文摘本文译自美国《Journal of chemical Education》1988年第8期.作者简介了密立根布居数分析法,并以此为基础讨论了键级和化合价,应用了别致的原子轨道线性组合分子轨道理论(LCAO—MO)的矩阵公式.最后给出了一些简单分子的计算结果,以说明这个理论的应用. | A.B.Sannigrahi Tapas Kar 杨金田 | 1990 | 湖州师范学院学报1990，0，5： | 3 |
| 14 | In vitro modulation of TH1 and TH2 cytokine expression by edible tuber of Dioscorea alata and study of correlation patterns of the cytokine expression显示文摘The underground tuber of Dioscorea alata is a palatable food and is also claimed to have therapeutic effects.Various groups of researchers demonstrated different activities of this tuber such as antioxidant,hepatoprotective,anti-ulcer and anti-diabetic activities.Therefore,the aim of the present study was to evaluate the immunomodulatory potentialities of 70%hydro-methanolic extract of D.alata underground tubers by investigating different parameters like the expression of interferon gamma(IFN-),interleukin(IL)-2,IL-4 and IL-10,in addition to its effect on the proliferation of murine splenic T-lymphocytes in vitro.Results demonstrated that D.alata can actively polarize the TH0 lymphocyte population towards the expression of TH1 immune response by up-regulating the IFN-and IL-2 expression and down-regulating the IL-4 and IL-10 expression.The tuber extract also proved to possess mitogenic activity as evidenced by the proliferation of lymphocytes in vitro.©2014 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Priyankar Dey Tapas Kumar Chaudhuri | 2014 | Food Science and Human Wellness2014，3，1： | 3 |
| 15 | Effect of sintering temperature on phase evolution of Al86Ni6Y4.5Co2La1.5 bulk amorphous composites synthesized via mechanical alloying and spark plasma sintering显示文摘Al86Ni6Y4.5Co2La1.5 amorphous powders were synthesized by mechanical alloying for 200 h. Subsequent consolidation was performed via spark plasma sintering in the temperature range of 250 ℃ to 500 ℃ at the pressure of 500 MPa. The role of viscous flow on densification was investigated by studying the viscosity change of the amorphous phase at different consolidation temperatures. The decrease in viscosity at higher sintering temperatures resulted in better particle bonding and densification of consolidated samples. The formation of only FCC Al was observed in the consolidated samples at sintering temperatures ≤ 300 ℃ and the intermetallic phases formed at temperatures ≥ 400 ℃. The mechanical properties of the bulk samples were measured by Vickers microhardness and nanoindentation tests. The testing results showed that the average values of microhardness, nanohardness and elastic modulus of the sample consolidated at 500 ℃ were 3.06 ± 0.14 GPa,4.85 ± 1.14 GPa and 89.53 ± 9.25 GPa, respectively. The increase in hardness and elastic modulus of the higher temperature consolidated samples is attributed to the improvement in particle bonding, densification and distribution of various hard intermetallic phases in the amorphous matrix. | Ashutosh Sahu Ram Sajeevan Maurya Tapas Laha | 2019 | Progress in Natural Science:Materials International2019，29，1： | 2 |
| 16 | 人胎盘提取液的抗炎和抗血小板聚集作用显示文摘AIM:To find the anti-inflammatory and anti-platelet aggregatory acivity of human placental extract(HPE,Placentrex),METHODS:The HPE was studied for anti-inflammatory effect in wistar rats on carrageenin,serotonin(5-HT),and prostaglandin E1(PGE1) induced edema in acute model and cotton pellet induced granuloma on sub-acute model.Anti-platelet aggregation was studied against protection of adinosine diphosphate (ADP)-induced aggregation of human platelet through in vitro study,RESULTS:HPE showed positive results both in acute and sub-acute models of inflammation.Highly significant(P<0.01),results were obtained against 5-HT induced acute inflammation and cotton pellet induced sub-acute inflammation in comparison with standard (diclofenac sodium)and control (normal saline) drugs.The anti-inflammatory property of HPE in animal model was well supported with clincal study of platelet aggregation.There was highly significant (P<0.01) inhibition of platelet aggregation with HPE at different doses against ADP.CONCLUSION:Our data suggest that human placental extract may be useful in suppressing inflammation and platelet aggregation. | SUR Tapas Kumar BISWAS Tuhin Kanti ALI Liaquat MUKHERJEE Biswapati | 2003 | Acta Pharmacologica Sinica2003，24，2： | 2 |
| 17 | A reinforcement learning approach to a single leg airline revenue management problem with multiple fare classes and overbooking显示文摘 | Abhijit Gosavi Naveen Bandla Tapas K. Das | 2002 | IIE Transactions2002，，9： | 1 |
| 18 | Substitution Patterns in Mono-BN-Fullerenes:Cn(n=20,24,28,32,36,and 40)显示文摘 | Tapas Kar Steve Scheiner | 2004 | Journal of Physical Chemistry A2004，108，： | 1 |
| 19 | Bipolar plates for PEM fuel cells:a review显示文摘 | Hermann Allen Chaudhuri Tapas Spagnol Priscila | 2005 | J Hydrogen Energy2005，30，12： | 1 |
| 20 | Multifunctional magnetite and silica-magnetite nanoparticles:synthesis,surface activation and applications in life sciences显示文摘 | Aranzazu del Campo Tapas Sen Jean-Paul Lellouche | 2005 | Journal of Magnetism and Magnetic Materials2005，293，： | 1 |
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