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| 1 | User Driven Innovation in the Building Process显示文摘During the late years there has been an ever-increasing focus on the possibilities to change the building process to raise quality on the final building products as well as the activities of actors involved in the building process. One reason for this interest is the new opportunities evolving due to introduction of advanced information and communication technology (ICT). The paper focuses on creative changes of the building process powered by user driven innovation activities. An overview of existing user driven innovation methodologies is given as well experiences from the ongoing Virtual Innovation in Construction (VIC) project. One important driving force for change is the opportunity for users to develop and articulate real needs concerning for example different functionalities of a building and its parts, but also on artifacts supporting the actual needs capture and requirements formulation during building design. A general methodological framework and meta ontology for Virtual Innovation in Construction is presented as well as findings from implementation of the method. | Per Christiansson Kistian Birch Sφrensen Mette Rφdtness Mette Abrahamsen Lars Ostenfeld Riemnann Morten Alsdorf | 2008 | Tsinghua Science and Technology2008，13，S1： | 4 |
| 2 | Pit-and trench-forming osteoclasts:a distinction that matters显示文摘Osteoclasts(OCs)seeded on bone slices either drill round pits or dig long trenches.Whereas pits correspond to intermittent resorption,trenches correspond to continuous and faster resorption and require a distinct assembly of the resorption apparatus.It is unknown whether the distinction between pits and trenches has any biological relevance.Using OCs prepared from different blood donors,we found that female OCs achieved increased resorption mainly through pit formation,whereas male OCs did so through trench formation.Trench formation went along with high collagenolytic activity and high cathepsin K(CatK)expression,thereby allowing deeper demineralization.A specific CatK inhibitor abrogated the generation of trenches,while still allowing the generation of pits.OCs obtained from bone marrow were more prone to generate trenches than those obtained from blood.Scanning electron microscopy of bone surfaces eroded in vivo showed trenches and pits of similar size as those made by OCs in culture.We conclude that the distinction between trench-and pit-forming OCs is relevant to the differences among OCs from different skeletal sites,different individuals,including gender,and results from differences in colIagenolytic power.This indicates a biological relevance and highlights the importance of discriminating between pits and trenches when assessing resorption. | Ditte MH Merrild Dinisha C Pirapaharan Christina M Andreasen Per Kjxrsgaard-Andersen Anas MJ Mùller Ming Ding Jean-Marie Delaissé Kent Sùe | 2015 | Bone Research2015，3，4： | 2 |
| 3 | Total homocysteine in plasma or serum: methods and clinical implications 显示文摘 | Per MU Helga R Sally P S | 1993 | Clin Chem1993，39，： | 1 |
| 4 | Single-sided natural ventilation driven by wind pressure and temperature difference 显示文摘 | Larsen Tine S Heiselberg Per | 2008 | Energy and Buildings2008，40，： | 1 |
| 5 | Field - Dependence/Independence: Ability in Relation to Mobility Fixity显示文摘 | Hansson S Birger Ryden Olof O Johnsson Per | 1986 | Perceptual and Motor Skills1986，63，1： | 1 |
| 6 | The interleukin-10 family of cytokines显示文摘 | FICKENSCHER H H?R S Küpers H | 2002 | Trends in Immunology2002，23，2： | 1 |
| 7 | Optimization of sheet metal forming processes by the use of numerical simulations显示文摘 | Toma(z) Pepelnjak Karl Kuzman | 2002 | Journal of Materials Processing Technology2002，13，： | 1 |
| 8 | High-speed heck reactions in ionic liquid with controlled microwave heating 显示文摘 | KARL S A V PER E MATS L | 2002 | J Org Chern2002，67，17： | 1 |
| 9 | Decreasing Time-Trends of Colorectal Cancer in a Large Cohort of Patients With Inflammatory Bowel Disease显示文摘 | Sverre S?derlund Lena Brandt Annika Lapidus Per Karlén Olle Brostr?m Robert L?fberg Anders Ekbom Johan Askling | 2009 | Gastroenterology2009，，5： | 1 |
| 10 | Levetiracetam monotherapy in newly diagnosed cryptogenic West syndrome 显示文摘 | Gumus H Kumandas S Per H | 2007 | Pediatr Neurol2007，37，5： | 1 |
| 11 | Biomarkers in sepsis at time zero:intensive care unit scores,plasma measurements and polymorphisms in Argentina显示文摘 | Perés Wingeyer SD Cunto ER Nogueras CM | | 0，，： | 1 |
| 12 | Endo-beta-1,4-Mannanases from bluemussel, Mytiluse edulis: purification, characterization andmode ofaction显示文摘 | XU B PER H HENRIK S | 2001 | J Biotechnol2001，2，： | 1 |
| 13 | 查看详情显示文摘 | Schuch R Garibian A Nygaard P Raymond S Araik G Hans H S Patrick J P Per N | | 0，，： | 1 |
| 14 | A multi-stage registration method using texture feathres 显示文摘 | JARC A PERS J KOVACIC S | 2010 | Journal of Digital Ima- ging2010，23，3： | 1 |
| 15 | Exploring the two-gene ratio in breast cancer—independent roles for HOXB13 and IL17BR in prediction of clinical outcome显示文摘 | Piiha-Lotta Jerevall Sara Brommesson Carina Strand Sofia Gruvberger-Saal Per Malmstr?m Bo Nordenskj?ld Sten Wingren Peter S?derkvist M?rten Fern? Olle St?l | 2007 | Breast Cancer Research and Treatment2007，，2： | 1 |
| 16 | Chemical surface modifications of microfibrillated cellulose显示文摘 | PER S MARTIN A BJORN S T | 2008 | Cellulose2008，15，： | 1 |
| 17 | A procedure-oriented generic bill of ma- terials显示文摘 | Kai A O Per S Ers T | 1997 | Computer Industry Engineering1997，32，1： | 1 |
| 18 | Dosimetric assessment of radiolabelled lipiodol as a potential therapeutic agent in colorectal liver metastases using combined CT and SPECT显示文摘 | Hind R Fleming J | 1994 | Nucl Med Commun1994，15，： | 1 |
| 19 | Human cardiac tissue induces transdifferentiation of adult stem cells towards cardiomyocytes显示文摘 | Macarena Perán Juan A. Marchal Elena López Manuel Jiménez-Navarro Houria Boulaiz Fernando Rodríguez-Serrano Esmeralda Carrillo Gema Sánchez-Espin Eduardo de Teresa David Tosh Antonia Aranega | 2010 | Cytotherapy2010，，3： | 1 |
| 20 | Tyrosine kinase inhibitor usage, treatment outcome, and prognostic scores in CML: report from the population-based Swedish CML registry显示文摘 | Martin H?glund Fredrik Sandin Karin Hellstr?m Mats Bj?reman Magnus Bj?rkholm Mats Brune Arta Dreimane Marja Ekblom S?ren Lehmann Per Ljungman Claes Malm Berit Markev?rn Kristina Myhr-Eriksson Lotta Ohm Ulla Olsson-Str?mberg Anders Sj?lander Hans Wadenvik | 2013 | Blood2013，，： | 1 |
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