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| 1 | Exocrine pancreatic insufficiency in adults:A shared position statement of the Italian association for the study of the pancreas显示文摘This is a medical position statement developed by the Exocrine Pancreatic Insufficiency collaborative group which is a part of the Italian Association for the Study of the Pancreas(AISP).We covered the main diseases associated with exocrine pancreatic insufficiency(EPI)which are of common interest to internists/gastroenterologists,oncologists and surgeons,fully aware that EPI may also occur together with many other diseases,but less frequently.A preliminary manuscript based on an extended literature search(Medline/PubMed,Cochrane Library and Google Scholar)of published reports was prepared,and key recommendations were proposed.The evidence was discussed at a dedicated meeting in Bologna during the National Meeting of the Association in October 2012.Each of the proposed recommendations and algorithms was discussed and an initial consensus was reached.The final draft of the manuscript was then sent to the AISP Council for approval and/or modification.All concerned parties approved the final version of the manuscript in June 2013. | Raffaele Pezzilli Angelo Andriulli Claudio Bassi Gianpaolo Balzano Maurizio Cantore Gianfranco Delle Fave Massimo Falconi Luca Frulloni the Exocrine Pancreatic Insufficiency collaborative(EPIc) Group | 2013 | World Journal of Gastroenterology2013，19，44： | 16 |
| 2 | Mucin-Producing Neoplasms of the Pancreas: An Analysis of Distinguishing Clinical and Epidemiologic Characteristics显示文摘 | Stefano Crippa Carlos Fernández–del Castillo Roberto Salvia Dianne Finkelstein Claudio Bassi Ismael Domínguez Alona Muzikansky Sarah P. Thayer Massimo Falconi Mari Mino–Kenudson Paola Capelli Gregory Y. Lauwers Stefano Partelli Paolo Pederzoli Andrew L. W | 2010 | Clinical Gastroenterology and Hepatology2010，，2： | 2 |
| 3 | HP-NAP inhibits the growth of bladder cancer in mice by activating a cytotoxic Th1 response显示文摘 | Gaia Codolo Matteo Fassan Fabio Munari Andrea Volpe Piefrancesco Bassi Massimo Rugge Francesco Pagano Mario Milco D’Elios Marina Bernard | 2012 | Cancer Immunology Immunotherapy2012，，1： | 2 |
| 4 | Incidence of cancer in the course of chronic pancreatitis显示文摘 | Giorgio Talamini Massimo Falconi Claudio Bassi Nora Sartori Roberto Salvia Erminia Caldiron Luca Frulloni Vincenzo Di Francesco Bruna Vaona Paolo Bovo Italo Vantini Paolo Pederzoli Giorgio Cavallini | 1999 | The American Journal of Gastroenterology1999，，5： | 2 |
| 5 | Resectable Pancreatic Cancer: Who Really Benefits From Resection?显示文摘 | Giuliano Barugola MD Stefano Partelli MD Stefano Marcucci MD Nora Sartori MD Paola Capelli MD Claudio Bassi MD Paolo Pederzoli MD Massimo Falconi MD | 2009 | Annals of Surgical Oncology2009，，12： | 2 |
| 6 | Middle Pancreatectomy: Indications, Short- and Long-term Operative Outcomes显示文摘 | Stefano Crippa Claudio Bassi Andrew L. Warshaw Massimo Falconi Stefano Partelli Sarah P. Thayer Paolo Pederzoli Carlos Fernández-del Castillo | 2007 | Annals of Surgery2007，，1： | 1 |
| 7 | Parenchyma-Preserving Resections for Small Nonfunctioning Pancreatic Endocrine Tumors显示文摘 | Massimo Falconi MD Alessandro Zerbi MD Stefano Crippa MD Gianpaolo Balzano MD Letizia Boninsegna MD Vanessa Capitanio MD Claudio Bassi MD Valerio Di Carlo MD Paolo Pederzoli MD | 2010 | Annals of Surgical Oncology2010，，6： | 1 |
| 8 | Parenchyma-Preserving Resections for Small Nonfunctioning Pancreatic Endocrine Tumors显示文摘 | Massimo Falconi MD Alessandro Zerbi MD Stefano Crippa MD Gianpaolo Balzano MD Letizia Boninsegna MD Vanessa Capitanio MD Claudio Bassi MD Valerio Di Carlo MD Paolo Pederzoli MD | 2010 | Annals of Surgical Oncology2010，，6： | 1 |
| 9 | Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial显示文摘 | Claudio Bassi Massimo Falconi Enrico Molinari William Mantovani Giovanni Butturini Andrew A Gumbs Roberto Salvia Paolo Pederzoli | 2003 | Surgery2003，，5： | 1 |
| 10 | Resectable Pancreatic Cancer: Who Really Benefits From Resection?显示文摘 | Giuliano Barugola Stefano Partelli Stefano Marcucci Nora Sartori Paola Capelli Claudio Bassi Paolo Pederzoli Massimo Falconi | 2009 | Annals of Surgical Oncology2009，，： | 1 |
| 11 | Parenchyma-Preserving Resections for Small Nonfunctioning Pancreatic Endocrine Tumors显示文摘 | Massimo Falconi Alessandro Zerbi Stefano Crippa Gianpaolo Balzano Letizia Boninsegna Vanessa Capitanio Claudio Bassi Valerio Di Carlo Paolo Pederzoli | 2010 | Annals of Surgical Oncology2010，，6： | 1 |
| 12 | The value of standard serum tumor markers in differentiating mucinous from serous cystic tumors of the pancreas: CEA, Ca 19-9, Ca 125, Ca 15-3显示文摘 | Claudio Bassi Roberto Salvia Andrew A. Gumbs Giovanni Butturini Massimo Falconi Paolo Pederzoli | 2002 | Langenbeck’s Archives of Surgery (-)2002，，7： | 1 |
| 13 | Long-term results of frey’s procedure for chronic pancreatitis: a longitudinal prospective study on 40 patients显示文摘 | Massimo Falconi M.D. Claudio Bassi M.D. Luca Casetti M.D. William Mantovani M.D. Giuseppe Mascetta M.D. Nora Sartori M.D. Luca Frulloni M.D. Paolo Pederzoli M.D | 2006 | Journal of Gastrointestinal Surgery2006，，4： | 1 |
| 14 | Three-dimensional collagen-based scaffold model to study the microenvironment and drug-resistance mechanisms of oropharyngeal squamous cell carcinomas显示文摘Objective:Squamous cell carcinoma(SCC)represents the most common histotype of all head and neck malignancies and includes oropharyngeal squamous cell carcinoma(OSCC),a tumor associated with different clinical outcomes and linked to human papilloma virus(HPV)status.Translational research has few available in vitro models with which to study the different pathophysiological behavior of OSCCs.The present study proposes a 3-dimensional(3 D)biomimetic collagen-based scaffold to mimic the tumor microenvironment and the crosstalk between the extracellular matrix(ECM)and cancer cells.Methods:We compared the phenotypic and genetic features of HPV-positive and HPV-negative OSCC cell lines cultured on common monolayer supports and on scaffolds.We also explored cancer cell adaptation to the 3 D microenvironment and its impact on the efficacy of drugs tested on cell lines and primary cultures.Results:HPV-positive and HPV-negative cell lines were successfully grown in the 3 D model and displayed different collagen fiber organization.The 3 D cultures induced an increased expression of markers related to epithelial–mesenchymal transition(EMT)and to matrix interactions and showed different migration behavior,as confirmed by zebrafish embryo xenografts.The expression of hypoxia-inducible factor 1α(1α)and glycolysis markers were indicative of the development of a hypoxic microenvironment inside the scaffold area.Furthermore,the 3 D cultures activated drug-resistance signaling pathways in both cell lines and primary cultures.Conclusions:Our results suggest that collagen-based scaffolds could be a suitable model for the reproduction of the pathophysiological features of OSCCs.Moreover,3 D architecture appears capable of inducing drug-resistance processes that can be studied to better our understanding of the different clinical outcomes of HPV-positive and HPV-negative patients with OSCCs. | Giacomo Miserocchi Claudia Cocchi Alessandro De Vita Chiara Liverani Chiara Spadazzi Sebastiano Calpona Giandomenico Di Menna Massimo Bassi Giuseppe Meccariello Giovanni De Luca Angelo Campobassi Maria Maddalena Tumedei Alberto Bongiovanni Valentina Fausti Franco Cotelli Toni Ibrahim Laura Mercatali | 2021 | Cancer Biology & Medicine2021，18，2： | 1 |
| 15 | Alcohol Intake, Cigarette Smoking, and Body Mass Index in Patients with Alcohol-associated Pancreatitis显示文摘 | Giorgio Talamini Bruna Vaona Claudio Bassi Paolo Bovo Tereza Damoc Marina Mastromauro Massimo Falconi Italo Vantini Giorgio Cavallini Paolo Pederzoli | 2000 | Journal of Clinical Gastroenterology2000，，4： | 1 |
| 16 | Prophylaxis for septic complications in acute necrotizing pancreatitis显示文摘 | Claudio Bassi Gerardo Mangiante Massimo Falconi Roberto Salvia Isabella Frigerio Paolo Pederzoli | 2001 | Journal of Hepato - Biliary - Pancreatic Surgery2001，，3： | 1 |
| 17 | Middle Pancreatectomy: Indications, Short- and Long-term Operative Outcomes显示文摘 | Stefano Crippa Claudio Bassi Andrew L. Warshaw Massimo Falconi Stefano Partelli Sarah P. Thayer Paolo Pederzoli Carlos Fernández-del Castillo | 2007 | Annals of Surgery2007，，1： | 1 |
| 18 | Following tracheal intubation, mucus flow is reversed in the semirecumbent position: Possible role in the pathogenesis of ventilator–associated pneumonia显示文摘 | Gianluigi Li Bassi Alberto Zanella Massimo Cressoni Mario Stylianou Theodor Kolobow | 2008 | Critical Care Medicine2008，，2： | 1 |
| 19 | HP-NAP inhibits the growth of bladder cancer in mice by activating a cytotoxic Th1 response显示文摘 | Gaia Codolo Matteo Fassan Fabio Munari Andrea Volpe Piefrancesco Bassi Massimo Rugge Francesco Pagano Mario Milco D’Elios Marina Bernard | 2012 | Cancer Immunology Immunotherapy2012，，1： | 1 |
| 20 | Alcohol and Smoking as Risk Factors in Chronic Pancreatitis and Pancreatic Cancer显示文摘 | Giorgio Talamini Claudio Bassi Massimo Falconi Nora Sartori Roberto Salvia Laura Rigo Armando Castagnini Vincenzo Di Francesco Luca Frulloni Paolo Bovo Bruna Vaona Giampaolo Angelini Italo Vantini Giorgio Cavallini Paolo Pederzoli | 1999 | Digestive Diseases and Sciences1999，，7： | 1 |
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