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| 1 | Pancreatic neuroendocrine neoplasms: Magnetic resonance imaging features according to grade and stage显示文摘AIM To describe magnetic resonance(MR) imaging features of pancreatic neuroendocrine neoplasms(Pan NENs) according to their grade and tumor-nodes-metastases stage by comparing them to histopathology and todetermine the accuracy of MR imaging features in predicting their biological behavior.METHODS This study was approved by our institutional review board; requirement for informed patient consent was waived due to the retrospective nature of the study. Preoperative MR examinations of 55 Pan NEN patients(29 men, 26 women; mean age of 57.6 years, range 21-83 years) performed between June 2013 and December 2015 were reviewed. Qualitative and quantitative features were compared between tumor grades and stages determined by histopathological analysis.RESULTS Ill defined margins were more common in G2-3 and stage Ⅲ-Ⅳ PanN ENs than in G1 and low-stage tumors(P < 0.001); this feature had high specificity in the identification of G2-3 and stage Ⅲ-Ⅳ tumors(90.3% and 96%, 95%CI: 73.1-97.5 and 77.7-99.8). The mean apparent diffusion coefficient value was significantly lower in G2-3 and stage Ⅲ-Ⅳ lesions compared to well differentiated and low-stage tumors(1.09 × 10-3 mm2/s vs 1.45 × 10-3 mm2/s and 1.10 × 10-3 mm2/s vs 1.53 × 10-3 mm2/s, P = 0.003 and 0.001). Receiving operator characteristic analysis determined optimal cutoffs of 1.21 and 1.28 × 10-3 mm2/s for the identification of G2-3 and stage Ⅲ-Ⅳ tumors, with sensitivity and specificity values of 70.8/80.7% and 64.5/64%(95%CI: 48.7-86.6/60-92.7 and 45.4-80.2/42.6-81.3).CONCLUSION MR features of PanN ENs vary according to their grade of differentiation and their stage at diagnosis and could predict the biological behavior of these tumors. | Riccardo De Robertis Sara Cingarlini Paolo Tinazzi Martini Silvia Ortolani Giovanni Butturini Luca Landoni Paolo Regi Roberto Girelli Paola Capelli Stefano Gobbo Giampaolo Tortora Aldo Scarpa Paolo Pederzoli Mirko D'Onofrio | 2017 | World Journal of Gastroenterology2017，23，2： | 16 |
| 2 | Postoperative pancreatic fistula: An international study group (ISGPF) definition显示文摘 | Claudio Bassi Christos Dervenis Giovanni Butturini Abe Fingerhut Charles Yeo Jakob Izbicki John Neoptolemos Michael Sarr William Traverso Marcus Buchler | 2005 | Surgery2005，，1： | 9 |
| 3 | Postoperative pancreatic fistula: An international study group (ISGPF) definition显示文摘 | Claudio Bassi Christos Dervenis Giovanni Butturini Abe Fingerhut Charles Yeo Jakob Izbicki John Neoptolemos Michael Sarr William Traverso Marcus Buchler | 2005 | Surgery2005，，1： | 6 |
| 4 | Early Versus Late Drain Removal After Standard Pancreatic Resections: Results of a Prospective Randomized Trial显示文摘 | Claudio Bassi Enrico Molinari Giuseppe Malleo Stefano Crippa Giovanni Butturini Roberto Salvia Giorgio Talamini Paolo Pederzoli | 2010 | Annals of Surgery2010，，2： | 5 |
| 5 | Comparison of imaging-based and pathological dimensions in pancreatic neuroendocrine tumors显示文摘AIM To establish the ability of magnetic resonance(MR) and computer tomography(CT) to predict pathologic dimensions of pancreatic neuroendocrine tumors(Pan NET) in a caseload of a tertiary referral center.METHODS Patients submitted to surgery for Pan NET at the Surgical Unit of the Pancreas Institute with at least 1 preoperative imaging examination(MR or CT scan) from January 2005 to December 2015 were included and data retrospectively collected. Exclusion criteria were: multifocal lesions, genetic syndromes, microadenomas or mixed tumors, metastatic disease and neoadjuvant therapy. Bland-Altman(BA) and Mountain-Plot(MP) statistics were used to compare size measured by each modality with the pathology size. Passing-Bablok(PB) regression analysis was used to check the agreement between MR and CT.RESULTS Our study population consisted of 292 patients. Seventy-nine(27.1%) were functioning Pan NET. The mean biases were 0.17 ± 7.99 mm, 1 ± 8.51 mm and 0.23 ± 9 mm, 1.2 ± 9.8 mm for MR and CT, considering the overall population and the subgroup of non-functioning-Pan NET, respectively. Limits of agreement(LOA) included the vast majority of observations, indicating a good agreement between imaging and pathology. The MP further confirmed this finding and showed that the two methods are unbiased with respect to each other. Considering ≤ 2 cm non-functioning-Pan NET, no statistical significance was found in the size estimation rate of MR and CT(P = 0.433). PBR analysis did not reveal significant differences between MR, CT and pathology.CONCLUSION MR and CT scan are accurate and interchangeable imaging techniques in predicting pathologic dimensions of Pan NET. | Salvatore Paiella Harmony Impellizzeri Elisabetta Zanolin Giovanni Marchegiani Marco Miotto Anna Malpaga Riccardo De Robertis Mirko D'Onofrio Borislav Rusev Paola Capelli Sara Cingarlini Giovanni Butturini Maria Vittoria Davì Antonio Amodio Claudio BassiAldo Scarpa Roberto Salvia Luca Landoni | 2017 | World Journal of Gastroenterology2017，23，17： | 4 |
| 6 | Pancreatic fistula: definition and current problems显示文摘 | Giovanni Butturini Despoina Daskalaki Enrico Molinari Filippo Scopelliti Andrea Casarotto Claudio Bassi | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，3： | 3 |
| 7 | Clinicopathological Correlates of Activating GNAS Mutations in Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas显示文摘 | Marco Dal Molin Hanno Matthaei Jian Wu Amanda Blackford Marija Debeljak Neda Rezaee Christopher L. Wolfgang Giovanni Butturini Roberto Salvia Claudio Bassi Michael G. Goggins Kenneth W. Kinzler Bert Vogelstein James R. Eshleman Ralph H. Hruban Anirban Mai | 2013 | Annals of Surgical Oncology2013，，12： | 2 |
| 8 | 慢性粒细胞白血病自体骨髓移植的策略与结果显示文摘因为常规治疗慢性粒细胞白血病(CML)不能治愈,而用同基因和HLA相匹配的供者作骨髓移植(BMT)能使CML患者长期生存,故对无适合供者的患者作自体骨髓移植(ABMT)令人关注。防止骨髓移植受者复发从同卵孪生及HLA匹配的同胞为CML进行BMT后的复发情况来看,BMT的抗白血病疗效有如下特点:白血病复发与病期及供者类型有关。 | Butturini A 陈令松 | 1991 | 国外医学(输血及血液学分册)1991，14，5： | 2 |
| 9 | Postoperative pancreatic fistula:an international study group(ISGPF) definition显示文摘 | Bassi C Dervenis C Butturini G | 2005 | Surg2005，138，1： | 1 |
| 10 | Postoperative pancreatic fistula:an international study group (ISGPF) definition显示文摘 | Bassi C Dervenis C Butturini G | 2005 | Surgery2005，138，1： | 1 |
| 11 | Pancreatic fistula:definition and current problems显示文摘 | Butturini G Daskalaki D Molinari E | 2008 | J Hepatobiliary Pancreat Surg2008，15，： | 1 |
| 12 | Pancreatic fistula: definition and current problems显示文摘 | Giovanni Butturini Despoina Daskalaki Enrico Molinari Filippo Scopelliti Andrea Casarotto Claudio Bassi | 2008 | Journal of Hepato - Biliary - Pancreatic Surgery2008，，3： | 1 |
| 13 | Postoperative pancreatic fistula: An international study group (ISGPF) definition显示文摘 | Claudio Bassi Christos Dervenis Giovanni Butturini Abe Fingerhut Charles Yeo Jakob Izbicki John Neoptolemos Michael Sarr William Traverso Marcus Buchler | 2005 | Surgery2005，，1： | 1 |
| 14 | Postoperative pancreatic fistula : an international study group ( ISGPF ) definition 显示文摘 | Bassi C Dervenis C Butturini G | 2005 | Surgery2005，138，1： | 1 |
| 15 | Testing a climato-topographic index for predicting wetlands distribution along an European climate gradient显示文摘 | Ph. Merot H. Squividant P. Aurousseau M. Hefting T. Burt V. Maitre M. Kruk A. Butturini C. Thenail V. Viaud | 2002 | Ecological Modelling2002，，1： | 1 |
| 16 | Postoperative pancreatic fistula:an international study group(ISGPF)definition显示文摘 | Bassi C Dervenis C Butturini G | | 0，，01： | 1 |
| 17 | Postoperative pancreatic fistula : an international study group (ISGPF) definition 显示文摘 | Bassi C Dervenis C Butturini G | 2005 | Sur- gery2005，138，1： | 1 |
| 18 | Postoperative pancreatic fistula:An International Study Group(ISGPF)definition显示文摘 | Bassi C Dervenis C Butturini G | 2005 | Surgery2005，138，1： | 1 |
| 19 | Postoperative pancreatic fistula:an international study group (ISGPF) definition显示文摘 | Bassi C Dervenis C Butturini G | | 0，，01： | 1 |
| 20 | A grading system can predict clinical and economic outcomes of pancreatic fistula after pancreaticoduodenectomy:results in 755 consecutive patients显示文摘 | Daskalaki D Butturini G Molinari E | | 0，，01： | 1 |
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