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| 1 | Fatigue Behavior of HDPE Composite Reinforced with Silane Modified TiO_2显示文摘The composite of high density polyethylene reinforced with silane-modified TiO2 particles (silane-TiO2/HDPE) is a potential bone substitute biomaterial. The structure, bioactivity, and mechanical properties of silane-TiO2/HDPE are analogous to those of natural bone, correspondingly. In order to investigate the effect of silane connection and saline solution on fatigue behaviors, flexural fatigue tests with this composite were carried out in both air and saline solution. Saline solution was found to have different effect on fatigue life. In saline solution, the fatigue life could be improved at stress levels lower than 30 MPa, while the fatigue life could be reduced at stress levels higher than 30 MPa. After analyzing the fracture morphologies, different failure mechanisms were proposed, and the important role of silane connection in the composite during the fatigue process was discussed. Silane connection cannot only support the loading stress but also hinder the failure process under loading effectively. For dry specimens, no interfacial failure between the filler and matrix was found. For wet specimens, it is inferred that the synergetic effect of saline solution and high concentrated stress at high stress level could easily destroy the silane connection, which accelerated the fracture process, whereas the synergetic effect of saline solution and silane connection at low stress level could promote the formation of more microcracks on sample surface, which hindered the final fracture. | C.X. Dong S.J. Zhu Mineo Mizuno Masami Hashimoto | 2011 | Journal of Materials Science & Technology2011，27，7： | 3 |
| 2 | 2D and 3D refraction-based visualization of breast cancer for early clinical check显示文摘Ductal carcinoma in-situ (DCIS) has been visualized by 2D XDFI (X-ray dark-field imaging) and further by a 3D X-ray CT, and the data was acquired by the X-ray optics DEI (diffraction-enhanced imaging). A newly made algorithm was used for CT. Data of 900 projections with interval of 0.2 degrees were used. Ductus lactiferi, microcalci-fication in a 3D form have been clearly visible. The spatial resolution available was approximately 30μm. | Masami ANDO Anton MAKSIMENKO Tetsuya YUASA Eiko HASHIMOTO Katsuhito YAMASAKI Shu IHIHARA Hiroshi SUGIYAMA Tokiko ENDO LI Gang CHEN Zhihua Kazuyuki HYODO Ei UENO | 2006 | Nuclear Science and Techniques2006，17，6： | 2 |
| 3 | Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying显示文摘 | Yoichiro Nakai Toshitaka Kido Kazunori Hashimoto Yoshio Kase Iwao Sakakibara Masami Higuchi Hiroshi Sasaki | 2002 | Journal of Ethnopharmacology2002，，1： | 1 |
| 4 | Construction material technology supporting social infrastructure显示文摘 | KASUGA Masami HASHIMOTO Osami NAKAMURA Nobuyuki | 2003 | JFE GIHO2003，，2： | 1 |
| 5 | Gastric undifferentiated carcinoma with diffuse c-kit overexpression and focal neuroendocrine differentiation显示文摘 | Daisuke Mori Michiaki Akashi Koichi Baba Kiyoto Morito Masami Shibaki Michinori Hashimoto Akashi Nakamura Seiko Mawatari Seiji Sato | 2013 | Pathology - Research and Practice2013，，2： | 1 |
| 6 | Upfront Thrombus Aspiration in Primary Coronary Intervention for Patients With ST-Segment Elevation Acute Myocardial Infarction显示文摘 | Yuji Ikari Masami Sakurada Ken Kozuma Shigeo Kawano Takaaki Katsuki Kazuo Kimura Takahiko Suzuki Takehiro Yamashita Akinori Takizawa Kazuo Misumi Hideki Hashimoto Takaaki Isshiki | 2008 | JACC: Cardiovascular Interventions2008，，： | 1 |
| 7 | Early branchings in the evolution of eukaryotes: Ancient divergence of entamoeba that lacks mitochondria revealed by protein sequence data显示文摘 | Masami Hasegawa Tetsuo Hashimoto Jun Adachi Naoyuki Iwabe Takashi Miyata | 1993 | Journal of Molecular Evolution1993，，4： | 1 |
| 8 | Hepatocellular carcinoma: Efficacy of transcatheter oily chemoembolization in relation to macroscopic and microscopic patterns of tumor growth among 100 patients with partial hepatectomy显示文摘 | Tohru Hashimoto M.D. Hironobu Nakamura Shinichi Hori Kaname Tomoda Katsuyuki Nakanishi Takamichi Murakami Takahiro Kozuka Morito Monden Mitsukazu Gotoh Chikazumi Kuroda Kenichi Wakasa Masami Sakurai | 1995 | Cardiovascular and Interventional Radiology1995，，2： | 1 |
| 9 | Risk factors for de novo hepatitis B during solid cancer treatment显示文摘BACKGROUND Reactivation of hepatitis B virus(HBV)during anticancer treatment is a critical issue.When treating patients with solid tumors,it is unclear whether specific cancer types or treatments affect HBV reactivation in hepatitis B surface antigen(HBsAg)-negative and hepatitis B core antibody(HBcAb)-positive patients,socalled de novo hepatitis B patients.The risk of de novo hepatitis B may vary based on different background factors.AIM To determine the frequency and risk factors for de novo hepatitis B during solid tumor treatment.METHODS This retrospective cohort study comprised 1040 patients without HBsAgs and with HBcAbs and/or hepatitis B surface antibodies(HBsAbs).The patients were treated for solid cancer from 2008 to 2018 at the National Kyushu Cancer Center and underwent HBV DNA measurements.Patient characteristics and disease and treatment information were investigated.HBV DNA measurements were performed using TaqMan polymerase chain reaction(PCR).To identify the risk factors associated with HBV DNA expression,the age,sex,original disease,pathology,treatment method,presence or absence of hepatitis C virus(HCV),and HBsAb and/or HBcAb titers of all subjects were investigated.In patients with HBV DNA,the time of appearance,presence of HBsAgs and HBsAbs at the time of appearance,and course of the subsequent fluctuations in virus levels were also investigated.RESULTS Among the 1040 patients,938 were HBcAb positive,and 102 were HBcAb negative and HBsAb positive.HBV DNA expression was observed before the onset of treatment in nine patients(0.9%)and after treatment in 35 patients(3.7%),all of whom were HBcAb positive.The HBV reactivation group showed significantly higher median HBcAb values[9.00(8.12-9.89)vs 7.22(7.02-7.43),P=0.0001]and significantly lower HBsAb values(14 vs 46,P=0.0342)than the group without reactivation.Notably,the reactivated group showed a significantly higher proportion of cancers in organs related to digestion and absorption(79.0%vs 58.7%,P=0.0051).A high HBcAb titer and cancers in organs involved in digestion and absorption were identified as independent factors for HBV reactivation(multivariate analysis,P=0.0002 and P=0.0095).The group without HBsAbs tended to have a shorter time to reactivation(day 43 vs day 193),and the frequency of reactivation within 6 mo was significantly higher in this group(P=0.0459)than in the other group.CONCLUSION A high HBcAb titer and cancers in organs involved in digestion and absorption are independent factors that contribute to HBV reactivation during solid tumor treatment. | Rie Sugimoto Masayuki Furukawa Takeshi Senju Yoshihusa Aratake Yuki Tanaka Hiroki Inada Tatsuya Noguchi Lingaku Lee Masami Miki Yuji Maruyama Risa Hashimoto Terumasa Hisano Mototsugu Shimokawa | 2020 | World Journal of Clinical Cases2020，8，24： | 1 |
| 10 | Construction material technology for supporting social infrastructure 显示文摘 | KASUGA Masami HASHIMOTO Osami NAKAMURA Nobuyuki | 2003 | JFE Gihou2003，，2： | 1 |
| 11 | LGR5‐Positive Colon Cancer Stem Cells Interconvert with Drug‐Resistant LGR5‐Negative cells and are Capable of Tumor Reconstitution显示文摘 | Shinta Kobayashi Hisafumi Yamada‐Okabe Masami Suzuki Osamu Natori Atsuhiko Kato Koichi Matsubara Yu Jau Chen Masaki Yamazaki Shinichi Funahashi Kenji Yoshida Eri Hashimoto Yoshinori Watanabe Hironori Mutoh Motooki Ashihara Chie Kato Takeshi Watanabe Takas | 2012 | STEM CELLS2012，，12： | 1 |
| 12 | Biomimetic hydration lubrication with various polyelectrolyte layers on cross-linked polyethylene orthopedic bearing materials显示文摘 | Masayuki Kyomoto Toru Moro Kenichi Saiga Masami Hashimoto Hideya Ito Hiroshi Kawaguchi Yoshio Takatori Kazuhiko Ishihara | 2012 | Biomaterials2012，，18： | 1 |
| 13 | A practical method for epoxidation of terminal olefins with 30%hydrogen peroxide under halide-free conditions显示文摘 | Kazuhiko Sato M A Masami Ogawa Tadashi Hashimoto | 1996 | J Org Chem1996，61，23： | 1 |
| 14 | Effect of the rhizomes of Atractylodes lancea and its constituents on the delay of gastric emptying显示文摘 | Yoichiro Nakai Toshitaka Kido Kazunori Hashimoto Yoshio Kase Iwao Sakakibara Masami Higuchi Hiroshi Sasaki | 2002 | Journal of Ethnopharmacology2002，，1： | 1 |
| 15 | Quantitative analysis of aristolochic acids, toxic compounds,contained in some medicinal plants 显示文摘 | Kazunori Hashimoto Masami Higuchi Bunsho Makino | 1999 | J Ethnopharmacol1999，64，： | 1 |
| 16 | Genotypes of canine distemper virus determined by analysis of the hemagglutinin genes of recent isolates from dogs in Japan显示文摘 | Masami Mochizuki Michiru Hashimoto Shigeyuki Hagiware | 1999 | J Clin Microbiol1999，37，： | 1 |
| 17 | Construction material technology supporting social infrastructure显示文摘 | KASUGA Masami HASHIMOTO Osami NAKAMURA Nobuyuki | 2003 | JFE Giho2003，2，： | 1 |
| 18 | Bacterial community dynamics in a full-scale municipal wastewater treatment plant employing conventional activated sludge process显示文摘 | Kurumi Hashimoto Masami Matsuda Daisuke Inoue Michihiko Ike | 2013 | Journal of Bioscience and Bioengineering2013，，： | 1 |
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