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| 1 | Hepatocellular carcinoma,human immunodeficiency virus and viral hepatitis in the HAART era显示文摘The incidence of hepatocellular carcinoma(HCC)in patients with human immunodeficiency virus(HIV) is rising.HCC in HIV almost invariably occurs in the context of hepatitis C virus(HCV)or hepatitis B virus (HBV)co-infection and,on account of shared modes of transmission,this occurs in more than 33% and 10% of patients with HIV worldwide respectively.It has yet to be clearly established whether HIV directly accelerates HCC pathogenesis or whether the rising incidence is an epiphenomenon of the highly active antiretroviral therapy(HAART)era,wherein the increased longevity of patients with HIV allows long-term complications of viral hepatitis and cirrhosis to develop.Answering this question will have implications for HCC surveillance and the timing of HCV/HBV therapy,which in HIV co-infection presents unique challenges.Once HCC develops,there is growing evidence that HIV co-infection should not preclude conventional therapeutic strategies,including liver transplantation. | Douglas C Macdonald Mark Nelson Mark Bower Thomas Powles | 2008 | World Journal of Gastroenterology2008，14，11： | 9 |
| 2 | A Meta-analysis of Transient Elastography for the Detection of Hepatic Fibrosis显示文摘 | Justin Stebbing Lavanta Farouk George Panos Mike Anderson Long R. Jiao Sundhiya Mandalia Mark Bower Brian Gazzard Mark Nelson | 2010 | Journal of Clinical Gastroenterology2010，，3： | 2 |
| 3 | Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial显示文摘 | John Primrose Stephen Falk Meg Finch-Jones Juan Valle Derek O’Reilly Ajith Siriwardena Joanne Hornbuckle Mark Peterson Myrddin Rees Tim Iveson Tamas Hickish Rachel Butler Louise Stanton Elizabeth Dixon Louisa Little Megan Bowers Sian Pugh O James Garden D | 2014 | Lancet Oncology2014，，6： | 2 |
| 4 | The use of modified bentonite for removal of aromatic organi from contaminated soil显示文摘 | Gitipour Saeid Bowers Mark T Bodoi Andrew | 1997 | Journal of Colloid and Interface Science1997，196，2： | 1 |
| 5 | The efficiency of modified bentonite clays for removal of aromatic or ganics from oily liquid wastes显示文摘 | Saeid Gitipour Mark T Bowers Warren Huff | 1997 | Spill Science & Technology Bulletin1997，，4： | 1 |
| 6 | Renal Nutcracker Syndrome: Surgical Options显示文摘 | Sameh M. Said Peter Gloviczki Manju Kalra Gustavo S. Oderich Audra A. Duncan Mark Fleming Thomas C. Bower | 2013 | Seminars in Vascular Surgery2013，，： | 1 |
| 7 | Studies on the allostimulatory function of dendritic cells from HCV-HIV-1 co-infected patients显示文摘There is increasing recognition of the potential morbidity and mortality associated with HIV-1 and hepatitis C (HCV)co-infection. HIV appears to adversely affect HCV disease while the reciprocal effect of HCV on HIV remains controversial.We therefore studied the effect of co-infection on dendritic cell function versus HIV infection alone, as previous work has shown that HCV impairs dendritic cell (DC) function. HIV-1 positive individuals with HCV were matched for CD4count, HIV- 1 RNA viral load and therapy, to HIV- 1 positive patients without HCV. Monocyte-derived DC were generated and mixed leukocyte reactions were performed. We assessed allostimulatory capacity with and without administration of exogenous Thl cytokines, using thymidine uptake and cell division analyses with the vital dye CFSE. We found that monocyte-derived DC from co-infected individuals showed no significant differences in allostimulatory capacity to ex vivo generated DC from HIV-1 infected individuals without HCV. Unlike the situation with HCV infection alone, this impairment was not reversed by increasing concentrations of either interleukin-2 or -12. Monocyte-derived DC from HIV-1 and HCV co-infected individuals have a similar allostimulatory capacity to DC from matched patients with HIV-1alone. These findings are compatible with results of prior clinical studies that found no evidence that HCV co-infection altered HIV disease progression and has implications for immunotherapeutic approaches in co-infected individuals. | Justin STEBBING Steve PATTERSON Simon PORTSMOUTH Claire THOMAS Robert GLASSMAN Adrian WILDFIRE Frances GOTCH Mark BOWER Mark NELSON Brian GAZZARD | 2004 | Cell Research2004，14，3： | 1 |
| 8 | Influence of chemotherapy for gestational trophoblastic diease on subsequent pregnancy outcome显示文摘 | Robert PW Mark Bower | 1998 | Br J Obstet Gynaecol1998，105，： | 1 |
| 9 | Cosgrove A Comparison of Oligogalacturonide - and Auxin - Induced Extracellular Alkalinization and Growth Responses in Roots of Intact Cucumber Seedlings显示文摘 | Mark D Spiro Jonathan F Bowers Daniel J | 2002 | Plant Physiology2002，130，： | 1 |
| 10 | The incidence and epidemiology of congenital upper limb anomalies: A total population study显示文摘 | Henk Giele Carolien Giele Carol Bower Mark Allison | 2001 | Journal of Hand Surgery2001，，4： | 1 |
| 11 | Measurement of repeatability of prompt flashlamp-induced wavefront aberration on beamlines at the National Ignition Faeility显示文摘 | D Homoelle Mark W Bowers Tracy Budge | 2011 | ApplOpt2011，50，22： | 1 |
| 12 | A secondary analysis of the moderating effects of depression and multimorbidity on the effectiveness of a chronic disease self-management programme显示文摘 | Mark Harrison David Reeves Elaine Harkness Jose Valderas Anne Kennedy Anne Rogers Mark Hann Peter Bower | 2011 | Patient Education and Counseling2011，，1： | 1 |
| 13 | The efficiency of modified bentonite clays for removal of aromatic organics from oily liquid wastes显示文摘 | Gitipour S Bowers Mark T Huff W | 1997 | Spill Science & Technology Bulletin1997，4，3： | 1 |
| 14 | The use of modified bentonite for removal of aromatic organics from contaminated soil显示文摘 | Gitipour Saeid Bowers Mark T Bodocsi Andrew | 1997 | Journal of Colloid and Interface Science1997，196，2： | 1 |
| 15 | The Relationship Between Prolonged Antiretroviral Therapy and Cryptogenic Liver Disease显示文摘 | Justin Stebbing Nick Wong Lionel Tan Andrew Scourfield Long Jiao Sami Shousha Deepa Grover Mark Bower Mark Nelson | 2009 | JAIDS Journal of Acquired Immune Deficiency Syndromes2009，，5： | 1 |
| 16 | Large- scale electrophysiology: Acquisition, com- pression, encryption, and storage of big data 显示文摘 | Benjamin H Brinkmann Mark R Bower Keith A Stengel | 2009 | Journal of Journal of Neuroscience Methods2009，，1： | 1 |
| 17 | Nature:大规模研究揭示生命所必需的基因显示文摘在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中,来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature期刊上,论文标题为“High—throughput discovery of novel developmental phenotypes”。 | Dickinson, Mary E. Flenniken, Ann M. Ji, Xiao Teboul, Lydia Wong, Michael D. White, Jacqueline K. Meehan, Terrence F. Weninger, Wolfgang J. Westerberg, Henrik Adissu, Hibret Baker, Candice N. Bower, Lynette Brown, James M. Caddle, L. Brianna Chiani, Francesco Clary, Dave Cleak, James Daly, Mark J. Denegre, James M. Doe, Brendan Dolan, Mary E. Edie, Sarah M. Fuchs, Helmut Gailus-Durner, Valerie Galli, Antonella Gambadoro, Alessia Gallegos, Juan Guo, Shiying Horner, Neil R. Hsu, Chih-Wei Johnson, Sara J. Kalaga, Sowmya Keith, Lance C. Lanoue, Louise Lawson, Thomas N. Lek, Monkol Mark, Manuel Arschall, Susan M. Mason, Jeremy McElwee, Melissa L. Newbigging, Susan Nutter, Lauryl M. J. Peterson, Kevin A. Ramirez-Solis, Ramiro Rowland, Douglas J. Ryder, Edward Samocha, Kaitlin E. Seavitt, John R. Selloum, Mohammed Szoke-Kovacs, Zsombor Tamura, Masaru Trainor, Amanda G. Tudose, Ilinca Wakana, Shigeharu Warren, Jonathan Wendling, Olivia West, David B. Wong, Leeyean Yoshiki, Atsushi MacArthur, Daniel G. Tocchini-Valentini, Glauco P. Gao, Xiang Flicek, Paul Bradley, Allan Skarnes, William C. Justice, Monica J. Parkinson, Helen E. Moore, Mark Wells, Sara Braun, Robert E. Svenson, Karen L. de Angelis, Martin Hrabe Herault, Yann Mohun, Tim Mallon, Ann-Marie Henkelman, R. Mark Brown, Steve D. M. Adams, David J. Lloyd, K. C. Kent McKerlie, Colin Beaudet, Arthur L. Bucan, Maja Murray, Stephen A. | 2016 | 现代生物医学进展2016，16，31： | 1 |
| 18 | A comparison of common bile duct pressures after botulinum toxin injection into the sphincter of Oddis versus biliary stenting in a canine model显示文摘 | Marks JM Bower AL Goormastic M | 2001 | Am J Surg2001，181，1： | 1 |
| 19 | Toll-like Receptor 4 Mediates Innate Immunity to Kaposi Sarcoma Herpesvirus显示文摘 | Dimitrios Lagos Richard James Vart Fiona Gratrix Samantha Jane Westrop Victoria Emuss Ping-Pui Wong Rebecca Robey Nesrina Imami Mark Bower Frances Gotch Chris Boshoff | 2008 | Cell Host & Microbe2008，，5： | 1 |
| 20 | Patterns of Coronary Compromise Resulting in Acute Right Ventricular Ischemic Dysfunction显示文摘 | Terry R. Bowers William W. O'Neill Mark Pica James A. Goldstein | 2002 | Circulation: Journal of the American Heart Association2002，，9： | 1 |
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