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| 1 | 非小细胞肺癌的个体化治疗进展显示文摘肺癌是全球癌症相关死亡的最常见原因.在过去20年中,分子靶向治疗和免疫治疗显著改善了非小细胞肺癌(non-small-cell lung cancer,NSCLC)患者的预后.然而,绝大多数的晚期NSCLC会对目前治疗产生耐药,最终出现疾病进展.基于此,本综述就近年来出现的一些突破性NSCLC治疗方法,尤其是免疫治疗和靶向治疗展开讨论.同时强调了目前我们对耐药机制的理解以及将基因组分析纳入临床研究以进一步理解机制的重要性.我们认为新辅助和联合的维持治疗在未来有可能使早期阶段疾病得到治愈.合理的联合治疗未来发展所面临的主要挑战是如何通过可靠的预测性生物标志物将患者清晰分层.本文阐述了我们对未来十年可能影响NSCLC治疗策略的临床研究领域的观点. | Meina WANG Roy S HERBST Chris BOSHOFF 杨雪(译校) 赵军(译校) | 2022 | 中国肺癌杂志2022，25，3： | 5 |
| 2 | An experimental study of service recovery options显示文摘 | Christo Boshoff | 1997 | International Journal of Service Industry Management1997，，2： | 2 |
| 3 | Empowerment, Attribution and Apologising as Dimensions of Service Recovery显示文摘 | Boshoff Christo and Leong Jason | 1998 | International Journal of Service Industry Management1998，9，1： | 1 |
| 4 | DNA metabolism in myco- bacterium tuberculosis: implications for drug resistance and strain variability 显示文摘 | Boshoff HI Durbach SI Mizrahi V | 2001 | Scand J Infect Dis2001，33，2： | 1 |
| 5 | Continuous low dose Thalidomide:a phase Ⅱ study in advanced melanoma,renal cell,ovarian and breast cancer显示文摘 | Boshoff C Mak I | 2000 | Br J Cancer2000，82，4： | 1 |
| 6 | Geologic History of the Central Zone of the Limpopo Complex:The West Alldays Area显示文摘 | BOSHOFF R VAN REENEN D D SMIT C A | 2006 | The Journal of Geology2006，114，6： | 1 |
| 7 | An experimental study of service recovery options 显示文摘 | C R Boshoff | 1997 | International Journal of Service Industry Management1997，，8： | 1 |
| 8 | Stenting the neonatal arterial duct in duct-dependent pulmonary circulation:new techniques,better results显示文摘 | Gewillig M Boshoff DE Dens J | 2004 | Journal of the American College of Cardiology2004，43，1： | 1 |
| 9 | The influence of successor-related factors on the succession process in small and medium-sizedfamily businesses显示文摘 | VENTERE BOSHOFF C MAAS G | 2005 | Feunily Business Review2005，18，4： | 1 |
| 10 | RECOVSAT: an instrument to measure satisfaction with transaction specific service recovery显示文摘 | Boshoff C | 1999 | Journal of Service Research1999，1，3： | 1 |
| 11 | PA-824 kills nonreplicating mycobacterium tuberculosis by intracellular NO release显示文摘 | Singh R Manjunatha U Boshoff HIM | 2008 | Science2008，322，5906： | 1 |
| 12 | The Relationships between Service Quality, Customer Satisfaction and Buying Intentions in The Private Hospital Industry显示文摘 | Boshoff C Gray B | 2004 | South African Journal of Business Management2004，35，4： | 1 |
| 13 | The contegra conduit in the right ventricular outflow tract induces supra valvular stenosis显示文摘 | Meyns B Garsse LV Boshoff D | 2004 | J Thorac Cardiovasc Surg2004，128，6： | 1 |
| 14 | Optimization of catechol production by membrane-Immobilized polyphenol oxidase: A modeling approach 显示文摘 | Boshoff A Burton M H Burton S G | 2003 | Biotechnology and Bioengineering2003，83，： | 1 |
| 15 | Continuous low dose thalidomide phase II study in advanced melanoma, renal cell, ovarian and breast cancer显示文摘 | Eisen T Boshoff C Mak I | 2000 | Br J Cancer2000，82，4： | 1 |
| 16 | Fibroblast growth factor-20 protects against dopamine neuron loss in vitro and provides functional protection in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease显示文摘 | SLEEMAN I J BOSHOFF E L DUTY S | 2012 | Neuropharmacology2012，63，7： | 1 |
| 17 | DnaE2 Polymerase Contributes to In Vivo survival and the emergence of drug resist- ance in Mycobacterium tuberculosis 显示文摘 | Boshoff HIM Reed MB Barry III CE | 2003 | Cell2003，113，2： | 1 |
| 18 | The Contegra conduit in the right ventficular outflow tract in duces supra valvular stenosis 显示文摘 | Meyns B Garsse LV Boshoff D | 2004 | J Thorac Cardiovasc Surg2004，128，6： | 1 |
| 19 | Understanding Service Recovery Satis- faction from a Service Encounter Perspective: A Pi- lot Study 显示文摘 | Boshoff C | 2007 | South African Journal of Business Management2007，38，2： | 1 |
| 20 | PA 824 kills nonrepli- caring Myeobacterium tuberculosis by intracellular NO release 显示文摘 | Singh R Manjunatha U Boshoff HI | 2008 | Science2008，322，5906： | 1 |
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