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| 1 | Non-antibiotic feed additives in diets for pigs:A review显示文摘A number of feed additives are marketed to assist in boosting the pigs' immune system, regulate gut microbiota, and reduce negative impacts of weaning and other environmental challenges.The most commonly used feed additives include acidifiers, zinc and copper, prebiotics, direct-fed microbials, yeast products, nucleotides, and plant extracts.Inclusion of pharmacological levels of zinc and copper, certain acidifiers, and several plant extracts have been reported to result in improved pig performance or improved immune function of pigs.It is also possible that use of prebiotics, direct-fed microbials, yeast,and nucleotides may have positive impacts on pig performance, but results have been less consistent and there is a need for more research in this area. | Yanhong Liu Charmaine D.Espinosa Jerubella J.Abelilla Gloria A.Casas L.Vanessa Lagos Su A.Lee Woong B.Kwon John K.Mathai Diego M.D.L.Navarro Neil W.Jaworski Hans H.Stein | 2018 | Animal Nutrition2018，，2： | 41 |
| 2 | 北京和上海市居民冬夏两季饮用水消费习惯(英文)显示文摘饮用水是人体暴露于有毒物质的重要暴露源,为了定量描述饮用水中污染物对暴露人群所造成的危害,世界各国的科学家们对饮用水的健康风险评价做了大量的研究.通常,健康风险评价需要污染物毒理学数据和暴露人群的暴露剂量数据.目前,针对很多的有毒污染物,国际上已经建立了应用于健康风险评价的毒理学数据库,同时积累了大量可用的有效数据.而对于暴露人群的暴露剂量数据,则是健康风险评价所要研究的重点.正确估计暴露人群的暴露剂量需要消费者提供大量的消费信息.例如,暴露人群每天消费的饮用水水量.美国环保局(EPA)认为成人每天消耗的饮用水水量为2L·d-1,此外,饮用水的消耗量会随着暴露人群的身体活动状况和所处环境状况(温度,湿度等)的改变而改变.目前,许多研究都是关于饮用水消费信息的,总体来讲这些研究结果基本上与美国环保局所采用的饮水消耗数据相一致.需要说明的是中国居民有完全不同于西方人的饮用水消费方式,如果在进行中国居民饮用水健康风险评价过程中应用美国环保局的假设会带来较大的不确定性.饮用水健康风险评价工作在我国开展并不多,尤其缺少中国居民饮用水消费习惯的数据库.这些客观条件使得在我国进行饮用水健康风险评价时只能从基础做起,积累有效的数据.本研究以北京和上海两座城市居民为研究对象,2002年到2004年分冬夏两季分别进行了4次饮用水消费习惯调查.研究采用随机入户方式(2004年至2005年),与中央电视台-索福瑞联合调查有限公司合作进行.参加调查的家庭从中央电视台入户收视率调查的基础数据库中随机抽取,在抽取过程中兼顾了不同城区、年龄结构、知识结构、收入水平等因素.研究表明,北京和上海居民冬夏两季的日均饮水量分别为2.2L·d-1、1.7L·d-1、2.0L·d-1和1.8L·d-1,这一结果和美国环保局的假设基本一致.同时本研究考察了性别、年龄、职业和季节对应用水消费习惯的影响.研究表明,日均饮水量随年龄的增加有增加的趋势,这一趋势在北京的夏季调查中趋势明显(p=0.01);男性的日均饮用水量大于女性,在上海冬季和夏季调查中均存在显著的差异(冬季:p=0.01;夏季:p=0.04);季节也同样影响被访者的日均饮水量,但是在4次调查中均未发现显著性差异.在北京冬季和夏季的调查中均发现了工作地点对饮用水消费习惯的显著影响(夏季p=0.01和冬季p=0.00).研究同样考察了居民饮用水消费类型,调查结果表明,煮沸后的自来水是中国居民最主要的日常饮品(上海夏季:58.3%;上海冬季67.9%;北京夏季:42.7%;北京冬季:60.0%).同时消费桶装纯净水的被访者也占有相当的比重(上海夏季:36.2%;上海冬季:24.7%;北京夏季:30.7%;北京冬季:60.0%).研究同时表明,在中国居民的日常生活中牛奶和豆奶已经成为重要的日常饮品.极少量的居民(北京夏季:10.7%;北京冬季5.7%;上海夏季1.2%;上海冬季0.6%)有直接饮用自来水的习惯.研究表明滞留水(在自来水水管中滞留6h以上的自来水)是对人体健康影响最大的水,而在我们的调查中,中国居民几乎不直接饮用滞留水.当前,饮用水健康风险评价在世界范围内蓬勃展开,但是这一技术在我国还处于起步阶段.本研究作为饮用水健康风险评价的前期工作,为其在中国的进一步发展提供了基础性的数据. | 徐鹏 黄圣彪 王子健 LAGO SGustavo | 2008 | 生态毒理学报2008，3，3： | 28 |
| 3 | 利用电阻率和探地雷达(GPR)法进行污染场地地球物理勘查——巴西圣保罗州里贝朗普雷图市润滑油废物处理区研究实例显示文摘地球物理方法在圈定废物处理区污染范围方面非常有效,有助于提高测深项目和监测井安装的效率。在研究区内,再精炼润滑油废弃物已堆积了近25年。为了开展此项研究,在该区开挖了4个总体积约25000m^3的沟槽。在沟槽底部和两侧未使用任何保护衬砌。本文目的是,评价电阻率和探地雷达法在描述巴西圣保罗州里贝朗普雷图市这种润滑油废物处理区污染的潜力,该润滑油废物处理区位于Serra Geral组玄武岩倾复带和Botucatu组砂岩的地质单元。采用二维剖面图显示方式揭示地球物理勘查结果。地球物理勘查结果表明:沟槽下部区域的电阻率(小于185Ωm)反映碳氢化合物中细菌的活动,与在以往文献中报告的由碳氢化合物引起污染的多个场地内观测结果类似。通过探地雷达法(GPR)可确定沟槽的几何形状。通过直接取样(监测井中地下水和土壤的化学分析)可证实污染的存在。在土样分析中发现,样品中存在多种低浓度的多环芳香碳氢化合物(PAH),这些化合物主要为萘和菲。通过水样分析证实地下水受到铅污染。在勘查期间使用的地球物理方法,为这种润滑油废物处理区研究提供了一种极好的环境描述手段,且在类似地区的研究中也可应用这些地球物理方法。 | Alexandre Lisboa Lago Vagner Roberto Elis 赵玉军(翻译) 武毅(校对) | 2009 | 水文地质工程地质技术方法动态2009，，3： | 3 |
| 4 | Aphis (Hemiptera: Aphididae) species groups found in the Midwestern United States and their contribution to the phylogenetic knowledge of the genus显示文摘类蚜虫属 Linnaeus 的发展史, 1 758 首先从在美国的中西部收集的标本被造。一个数据矩阵与有翼、无翅的胎生的女性的各自的字符国家与 68 种类和 41 个词法字符被构造。用 UPGMA (有算术平均数的未加权的对组方法) 执行的分析的 Dendrogram 拓扑学,最大的吝啬和细胞色素 Oxidase 的贝叶斯的分析我,延伸因素 1-α
并且主要 endosymbiont Buchnera aphidicola 16S 序列不适合。贝叶斯的分析强烈支持了种系发生的树的大多数终端节点。发展史被 COI 的 EF1-α 和 EF1-α 强烈支持分子的数据与词法人物结合了。它没被 COI 或 Buchnera aphidicola 16S 的单个分析支持。从贝叶斯的发展史的结果给 4 个主要种类组看:asclepiadis, fabae, gossypii,和 middletonii。结果地方蚜虫属和类 Protaphis Börner 的种类, 1952, Toxoptera Koch, 1856 并且 Xerobion Nevsky, 1928 在 monophyletic clade。词法人物也 monophyly 支持这。发展史证明北美的 middletonii 种类组的 monophyletic clade 属于类 Protaphis:P。debilicornis (吉勒特与帕尔默, 1929 ) ,梳子。nov, P。echinaceae (拉各斯和 Voegtlin, 2009 ) ,梳子。nov,和 P。middletonii (托马斯, 1879 ) 。类 Toxoptera 应该被认为蚜虫属的亚属(stat。nov ) 。分析也显示当前的类 Iowana Frison, 1954 应该被认为蚜虫属的亚属(stat。nov ) 。 | Doris M. Lagos David J. Voegtlin Armelle Coeur d'aciert Rosanna Giordano | 2014 | Insect Science2014，21，3： | 2 |
| 5 | Plasma triglyceride levels and body mass index values are the most important determinants of preβ-1 HDL concentrations in patients with various types of primary dyslipidemia显示文摘 | Vasilis Tsimihodimos Irene Gazi Theodosios Filippatos Michael Kostapanos Kostantinos Lagos Christina Kostara Constantinos C. Tellis Moses Elisaf Alexandros D. Tselepis | 2009 | Atherosclerosis2009，，2： | 2 |
| 6 | Blatella germanica as a possible cockroach vector of micro-organisms in a hospital显示文摘 | G. Risco Oliva C. Díaz O. Fuentes González M.D. Martínez C. Fernández R. Cordoví P. Más Lago N. Herrera | 2009 | Journal of Hospital Infection2009，，1： | 2 |
| 7 | Influence of the concentration of dietary digestible calcium on growth performance,bone mineralization, plasma calcium, and abundance of genes involved in intestinal absorption of calcium in pigs from 11 to 22 kg fed diets with different concentrations of显示文摘Background: A 21-day experiment was conducted to test the hypothesis that Ca requirements to maximize growth performance expressed as the standardized total tract digestible(STTD) Ca to STTD P ratio is less than 1.40:1. The second hypothesis was that increasing dietary Ca increases plasma Ca concentration and downregulates abundance of genes related to Ca absorption(TRPV6, S100 G, and ATP2 B1) in the duodenum, and tight junction proteins(OCLN, CLDN1, and ZO1) in the duodenum and ileum.Methods: Twenty corn-soybean meal diets were formulated using a 4 × 5 factorial design with diets containing 0.16%, 0.33%, 0.42%, or 0.50% STTD P, and 0.14%, 0.29%, 0.44%, 0.59%, or 0.74% STTD Ca. Six hundred and forty pigs(initial weight: 11.1 ± 1.4 kg) were allotted to 20 diets and 5 blocks in a randomized complete block design. On day21, weights of pigs and feed left in feeders were recorded and blood, duodenal tissue, ileal mucosa, and the right femur were collected from 1 pig per pen. Abundance of m RNA was determined in duodenal and ileal tissue via quantitative RT-PCR. Data were analyzed using a response surface model.Results: The predicted maximum ADG(614 g), G:F(0.65), and bone ash(11.68 g) was obtained at STTD Ca:STTD P ratios of 1.39:1, 1.25:1, and 1.66:1, respectively, when STTD P was provided at the requirement(0.33%). If dietary STTD P was below the requirement, increasing dietary Ca resulted in reduced(P < 0.05) ADG and G:F. However, if dietary STTD P was above the requirement, negative effects(P < 0.05) on ADG and G:F of increasing STTD Ca were observed only if dietary STTD Ca exceeded 0.6%. Plasma Ca concentration was positively affected by STTD Ca over the range studied(quadratic, P < 0.01) and negatively affected by increasing STTD P(linear, P < 0.01). There was a linear negative effect(P < 0.05) of STTD Ca on the abundance of S100 G, TRPV6, OCLN, and ZO1 in duodenum, and CLDN and ZO1 in ileum.Conclusions: The STTD Ca:STTD P ratio needed to maximize growth performance of 11-to 25-kg pigs is less than1.40:1, if P is at the estimated requirement. Increasing dietary Ca reduces transcellular absorption of Ca and increases paracellular absorption of Ca. | L.Vanessa Lagos Su A.Lee Guillermo Fondevila Carrie L.Walk Michael R.Murphy Juan J.Loor Hans H.Stein | 2019 | Journal of Animal Science and Biotechnology2019，10，4： | 2 |
| 8 | Partial oxidation of methanol to produce hydrogen over Cu-Zn-based catalysts 显示文摘 | Alejo L Lago R Pena M A | 1997 | Appl Catal A1997，162，12： | 1 |
| 9 | Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library显示文摘 | Lagos D Honegger A | 2003 | Nat Biotechnol2003，21，： | 1 |
| 10 | New microRNAs from mouse and human显示文摘 | Rauhut R Meyer J | 2003 | RNA2003，9，2： | 1 |
| 11 | A dynamic decision support system for farm water management in surface irrigation: modal development and application显示文摘 | Carlos I Flores Eduardo A Holzapfel Octavio Lagos | 2010 | Chilean journal of agricultural research2010，70，2： | 1 |
| 12 | Correction for chromosome-17 is critical for the determination of true Her-2/neu gene amplification status in breast cancer显示文摘 | Dal Lago L Durbecq V Desmedt C | 2006 | Mol Cancer Ther2006，5，10： | 1 |
| 13 | Leptin beyond body weightregulation-current concepts concerning its role in immune functionand inflammation显示文摘 | Lago R Gómez R Lago F | 2008 | Cell Immunol2008，252，12： | 1 |
| 14 | Chronic inflammation modulates ghrelin levels in humans and rats显示文摘 | Otero M Nogueiras R Lago F | 2004 | Rheumatology2004，43，： | 1 |
| 15 | Tumor necrosis factor- alpha and the cytokine network in psoriasis 显示文摘 | Brotas AM Cunha JM Lago EH | 2012 | An Bras Demmtol2012，87，5： | 1 |
| 16 | Laparoscopic testicular autotransplantation显示文摘 | Sánchez de Badajoz E Miguélez Lago C del Rosal Samaniego JM | 1992 | Arch Esp Urol1992，45，10： | 1 |
| 17 | A new player in cartilage homeostasis:adiponectin induces nitric oxide synthase type Ⅱ and pro-inflammatory cytokines in chondrocytes显示文摘 | Lago R Gomez G Otero M | | 0，，09： | 1 |
| 18 | A new player in cartilage home-ostasis:adiponeotin induces nitric oxide synthase type Ⅱ and pro-inflammatory cytokines in chondrocytes显示文摘 | Lago R Gomezr Oterom | 2008 | Osteoarthritis Cartil-age2008，16，9： | 1 |
| 19 | New microRNAs from mouse and human显示文摘 | Lagos QM Rauhut R Meyer J | 2003 | RNA2003，9，2： | 1 |
| 20 | An oscillometric detector for capillary electrophoresis显示文摘 | Fracassi da Silva J A do Lago C L | 1998 | Anal Chem1998，70，20： | 1 |
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