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    题名 作者 年代 出处 被引量
1全球防盲资讯显示文摘Margreet Hogeweg 2007实用防盲技术2007,,1:11
2The FAIR Funding Model:Providing a Framework for Research Funders to Drive the Transition toward FAIR Data Management and Stewardship Practices显示文摘A growing number of research funding organizations(RFOs)are taking responsibility to increase the scientific and social impact of research output.Also reusable research data are recognized as relevant output for gaining impact.RFOs are therefore promoting FAIR research data management and stewardship(RDM)in their research funding cycle.However,the implementation of FAIR RDM still faces important obstacles and challenges.To solve these,stakeholders work together to develop innovative tools and practices.Here we elaborate on the role of RFOs in developing a FAIR funding model to support the FAIR RDM in the funding cycle,integrated with research community specific guidance,criteria and metadata,and enabling automatic assessments of progress and output from RDM.The model facilitates to create research data with a high level of FAIRness that are meaningful for a research community.To fully benefit from the model,RFOs,research institutions and service providers need to implement machine actionability in their FAIR RDM tools and procedures.As many stakeholders still need to get familiar with“human actionable”FAIR data practices,the introduction of the model will be stepwise,with an active role of the RFOs in driving FAIR RDM processes as effectively as possible.Margreet Bloemers Annalisa Montesanti 2020Data Intelligence2020,2,1:4
3Trends in treatment and overall survival among patients with proximal esophageal cancer显示文摘BACKGROUND The management of proximal esophageal cancer differs from that of tumors located in the mid and lower part of the esophagus due to the close vicinity of vital structures.Non-surgical treatment options like radiotherapy and definitive chemoradiation(CRT)have been implemented.The trends in(non-)surgical treatment and its impact on overall survival(OS)in patients with proximal esophageal cancer are unclear,related to its rare disease status.To optimize treatment strategies and counseling of patients with proximal esophageal cancer,it is therefore essential to gain more insight through real-life studies.AIM To establish trends in treatment and OS in patients with proximal esophageal cancer.METHODS In this population-based study,patients with proximal esophageal cancer diagnosed between 1989 and 2014 were identified in the Netherlands Cancer Registry.The proximal esophagus consists of the cervical esophagus and the upper thoracic section,extending to 24 cm from the incisors.Trends in radiotherapy,chemotherapy,and surgery,and OS were assessed.Analyses were stratified by presence of distant metastasis.Multivariable Cox proportional hazards regression analyses was performed to assess the effect of period of diagnosis on OS,adjusted for patient,tumor,and treatment characteristics.RESULTS In total,2783 patients were included.Over the study period,the use of radiotherapy,resection,and CRT in non-metastatic disease changed from 53%,23%,and 1%in 1989-1994 to 21%,9%,and 49%in 2010-2014,respectively.In metastatic disease,the use of chemotherapy and radiotherapy increased over time.Median OS of the total population increased from 7.3 mo[95%confidence interval(CI):6.4-8.1]in 1989-1994 to 9.5 mo(95%CI:8.1-10.8)in 2010-2014(logrank P<0.001).In non-metastatic disease,5-year OS rates improved from 5%(95%CI:3%-7%)in 1989-1994 to 13%(95%CI:9%-17%)in 2010-2014(logrank P<0.001).Multivariable regression analysis demonstrated a significant treatment effect over time on survival.In metastatic disease,median OS was 3.8 mo(95%CI:2.5-5.1)in 1989-1994,and 5.1 mo(95%CI:4.3-5.9)in 2010-2014(logrank P=0.26).CONCLUSION OS significantly improved in non-metastatic proximal esophageal cancer,likely to be associated with an increased use of CRT.Patterns in metastatic disease did not change significantly over time.Judith de Vos-Geelen Sandra ME Geurts Liselot BJ Valkenburg-van Iersel Evelien JM de Jong Vivianne CG Tjan-Heijnen Margreet van Putten Valery EPP Lemmens Heike I Grabsch Nadia Haj Mohammad Frank JP Hoebers Chantal V Hoge Paul M Jeene Hanneke WM van Laarhoven Tom Rozema Marije Slingerland Grard AP Nieuwenhuijzen 2019World Journal of Gastroenterology2019,25,47:2
4Developmental regulation of RI TL-DNA gene expression in roots, shoots and tubers of transformed potato (Solanum tuberosum cv. Desiree)显示文摘Gert Ooms David Twell Margreet E. Bossen J. Harry C. Hoge Michael M. Burrell 1986Plant Molecular Biology1986,,5:2
5Membrane-type matrix metalloproteinases and ascularization in human endometrium during the menstrual cycle显示文摘Margreet P 2006Mol Hum Reprod2006,12,1:1
6MRI assessment of knee osteoarthritis: Knee Osteoarthritis Scoring System (KOSS)—inter-observer and intra-observer reproducibility of a compartment-based scoring system显示文摘Peter R. Kornaat Ruth Y. T. Ceulemans Herman M. Kroon Naghmeh Riyazi Margreet Kloppenburg Wayne O. Carter Thasia G. Woodworth Johan L. Bloem 2005Skeletal Radiology2005,,2:1
7T-staging of rectal cancer: accuracy of 3.0?Tesla MRI compared with 1.5?Tesla显示文摘Monique Maas Doenja Lambregts Max Lahaye Geerard Beets Walter Backes Roy Vliegen Margreet Osinga-de Jong Joachim Wildberger Regina Beets-Tan 2012Abdominal Imaging2012,,3:1
8Predictors of sudden cardiac death after mustard or senning repair for transposition of the great arteries显示文摘Janneke A.E. Kammeraad Carolien H.M. van Deurzen Narayanswami Sreeram Margreet Th.E. Bink-Boelkens Jaap Ottenkamp Willem A. Helbing Jan Lam Martha A. Sobotka-Plojhar Otto Daniels Seshadri Balaji 2004Journal of the American College of Cardiology2004,,5:1
9Exploring the Politics of Water Grabbing:The Case of Large Mining Operation in the Peruvian Andes显示文摘Sosa Milagros Margreet Zwarteveen 0,,02:1
10Bacterial load in relation to vacuum-assisted closure wound therapy:A prospective randomized trial显示文摘Chantal M Margreet C Gert-jan CM 2004Wound Repair and Regeneration2004,1,:1
11Long-term effects of heavy metals on aquatic plants显示文摘Madelijn van der Werff Margreet J Pruyt 1982Chemosphere1982,11,8:1
12Increasing the number of hepatitis B vaccine injections augments anti-HBs response rate in HIV-infected patients. Effects on HIV-1 viral load显示文摘David Rey Véronique Krantz Marialuisa Partisani Marie-Paule Schmitt Pierre Meyer Eric Libbrecht Marie-Josée Wendling Denis Vetter Margreet Nicolle Georgette Kempf-Durepaire Jean-Marie Lang 2000Vaccine2000,,:1
13Real-time PCR for detection and quantification of fungal and oomycete tomato pathogens in plant and soil samples显示文摘Bart Lievens Margreet Brouwer Alfons C.R.C. Vanachter Bruno P.A. Cammue Bart P.H.J. Thomma 2006Plant Science2006,,1:1
14Influence of acetylcholine agonists and antagonists on the swelling of etiolated wheat (Triticum aestivum L.) mesophyll protoplasts显示文摘Andrzej Tretyn Richard E. Kendrick Margreet E. Bossen Willem J. Vredenberg 1990Planta1990,,4:1
15Bone marrow edema-like lesions change in volume in the majority of patients with osteoarthritis; associations with clinical features显示文摘Peter R. Kornaat Margreet Kloppenburg Ruby Sharma Stella A. Botha-Scheepers Marie-Pierre Hellio Graverand L. Napoleon J. E. M. Coene Johan L. Bloem Iain Watt 2007European Radiology2007,,12:1
16Psychometric qualities of the Dutch version of the Pediatric Inventory for Parents(PIP):a multi-center study显示文摘Vrijmoet-Wiersma Hoekstra-Weebers Margreet DP 2010Psycho-Oncology2010,19,:1
17The role of nasal carriage in Staphylococcus aureus infections显示文摘Heiman FL Wertheim Damian C Melles Margreet C Vos Willem van Leeuwen Alex van Belkum Henri A Verbrugh Jan L Nouwen 2005The Lancet Infectious Diseases2005,,12:1
18Water:from basic need to commodity:a discussion on gender and water rights in the context of irrigation显示文摘ZWARTEVEEN MARGREET Z 1997World Development1997,25,8:1
19New fluorescent method (PLT-F) on Sysmex XN2000 hema- tology analyzer achieved higher accuracy in low platelet counting显示文摘Schoorl Margreet Schoorl Marianne Oomes Jeanette e al 2013Am J Clin Pathol2013,140,4:1
20The role of nasal carriage in Staphylococcus aureus infections显示文摘Heiman FL Wertheim Damian C Melles Margreet C Vos Willem van Leeuwen Alex van Belkum Henri A Verbrugh Jan L Nouwen 2005The Lancet Infectious Diseases2005,,12:1
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