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| 1 | 肝上腔静脉成形术联合肝后腔静脉扩展术在肝移植中的应用:首次115例经验报道显示文摘目的:本文介绍原位肝移植中腔静脉成形术的方法并评估其结果。方法:1994年11月至2000年9月,我们对连续115例原位肝移植(包括6例左外侧叶及2例右叶移植)病人采用了腔静脉成形术。 在起初的4年里,53例(66.3%)移植病人需行股-腋静脉体外转流,而以后的2年内该比例降至8例(22.9%)。无一例病人需中转为背驮式或经典术式。结果:中位手术时间4.5h,中位热缺血时间25min,中位输血量6U浓缩红细胞。上述结果在首次移植及再次移植间无差异。本组无与腔静脉成形技术相关的围手术期死亡。包括活体原位肝移植在内,均未观察到肝静脉流出道梗阻。没有病人因急性肾功能衰竭而需术后血透。病人留置于ICU的中位天数2d,中位住院天数为10d。结论:腔静脉成形术无需解剖肝后腔静脉、肝静脉或肝短静脉,肝下腔静脉也得以保留,并因此更有利于肝切除及维持稳定的血流动力学,在再次移植中优势更为明显。大开口的三角形腔静脉吻合容易操作,能在较短时间内完成供肝植入,且易与吻合血管口径的匹配,并可避免流出道阻塞。操作时间的缩短减少了静脉体外转流的可能。我们认为腔静脉成形技术能适用于所有病人,且相应手术的并发症少。 | You Min Wu Michael Voigt Stephen Rayhili Daniel Kartz Rou-Yee Chenhsu Warren Schmidt Rachel Miller Frank Mtros Douglas Labrecque 周光文 | 2002 | 外科理论与实践2002，7，2： | 7 |
| 2 | Mental and physical symptoms associated with lower social support for patients with hepatitis C显示文摘AIM: To systematically examine the impact of the hepatitis C virus (HCV) diagnosis on patients' level of social support in a large-scale study. METHODS: Patients evaluated and treated for HCV in a tertiary referral center were enrolled in a cross-sectional study. Demographic data, functional and emotional status as measured by the Hospital Anxiety and Depression Scale (HAD) and the Sickness Impact Profile (SIP), severity of liver disease, mode of acquisition, and physical and psychiatric comorbidities were collected from patients or abstracted from the medical record. All participants completed a semi-structured interview, addressing questions of social support. RESULTS: A total of 342 patients (mean age 45.2 years; 37% women) were enrolled. Ninety-two (27%) patients described lower levels of support by family and friends. Nearly half of the participants (45%) noted the loss of at least one relationship due to the disease. Fears related to transmitting the disease (25%) were common and often associated with ignorance or even discrimination by others (19%). Nearly one fifth of the patients did not share information about their disease with others to avoid being stigmatized. Lower levels of social support were significantly associated with living alone, being unemployed, being excluded from antiviral therapy, having psychiatric comorbidities, contracting HCV through intravenous drug use, having high levels of anxiety and depression as measured by the HAD and negative mood state as measured by the SIP. Patients reporting lower levels of social support also noted more physical symptoms as measured by the SIP. CONCLUSION: Patients with hepatitis C often face significant social problems, ranging from social isolation to familial stress. The most common concerns reflect a limited insight of patients and their relatives and friends about the disease, the risk factors for its spread, and about potential consequences. Our data suggest that educational interventions targeting support persons and the stressors identified in our findings may lessen or alleviate the social strains patients with hepatitis C experience. | Julie A Blasiole Laura Shinkunas Douglas R LaBrecque Robert M Arnold Susan L Zickmund | 2006 | World Journal of Gastroenterology2006，12，29： | 5 |
| 3 | World Gastroenterology Organisation Global Guidelines: Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis显示文摘 | Douglas R. LaBrecque Zaigham Abbas Frank Anania Peter Ferenci Aamir G. Khan Khean-Lee Goh Saeed S. Hamid Vasily Isakov Maribel Lizarzabal Manuel M. Pe?aranda Juan F.R. Ramos Shiv Sarin Davor Stimac Alan B.R. Thomson Muhammed Umar Justus Krabshuis Anton Le | 2014 | Journal of Clinical Gastroenterology2014，，6： | 3 |
| 4 | Hepato eellular carcinoma (HCC):a global perspective显示文摘 | Ferenci P Fried M Labrecque D | 2010 | J Clin Gastroenterol2010，44，4： | 1 |
| 5 | Identification ofdifferentially expressed genes in a porcine in vivo model ofadipogenesis using suppression subtractive hybridization 显示文摘 | Labrecque B Mathieu 0 Bordignon V | 2009 | Comp Biochem PHys D2009，4，： | 1 |
| 6 | Citrate esters as plasticizers for poly (lactic acid) 显示文摘 | Labrecque L V Kumar R A Dave V | 1997 | Journal of Applied Polymer Science1997，66，： | 1 |
| 7 | Cytoprotective effect of proanthocyanidin-rich cranberry fraction against bacterial cell wall-mediated toxicity in macrophages and epithelial cells 显示文摘 | La VD Labrecque J Grenier D | 2009 | Phytother Res2009，23，10： | 1 |
| 8 | Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol显示文摘 | Labrecque L Royal I Surprenant DS | 2003 | Mol Biol Cell2003，14，1： | 1 |
| 9 | Effects of carrying a pregnancy and of method of delivery on urinary incontinence: a prospective cohort study 显示文摘 | Eason E Labrecque M Marcoux S | 2004 | BMC Pregnant and Childbirth2004，4，1： | 1 |
| 10 | Can- cer risk in systemic lupus: an updated international multi- centrecohort study显示文摘 | Bernatsky S Ramsey-Goldman R Labrecque J | 2013 | J Autoimmun2013，42，： | 1 |
| 11 | Two-Dimensional Cross- Borehole Resistivity Model Fitting显示文摘 | LaBrecque D J Ward S H | 1990 | Geotechnical and Environmental Geophysics1990，1，： | 1 |
| 12 | Hepatocellular Carcinoma (HCC): A Global Perspective显示文摘 | Peter Ferenci Michael Fried Douglas Labrecque Jordi Bruix Morris Sherman Masao Omata Jenny Heathcote Teehra Piratsivuth Mike Kew Jesse A. Otegbayo S.S. Zheng S. Sarin Saeed S. Hamid Salma Barakat Modawi Wolfgang Fleig Suliman Fedail Alan Thomson Aamir Kha | 2010 | Journal of Clinical Gastroenterology2010，，4： | 1 |
| 13 | Higher BMI is associated with worse asthma control and quality of Life but not asthma severity显示文摘 | Lavoie KL Bacon SL Labrecque M | | 0，，： | 1 |
| 14 | Magnetic lineations in the Pacific Jurassic quiet zone 显示文摘 | Cande S C Larson R L LaBrecque J L | 1978 | Earth and Planetary Science Letters1978，41，： | 1 |
| 15 | Two polymorphic variants of wild-type p53 differ biochemically and biologically显示文摘 | Thomas M Kalita A Labrecque S | 1999 | Mol Celt Bio11999，19，2： | 1 |
| 16 | Partial characterization of hepatic re- generation stimulator substance from rat liver 显示文摘 | LaBrecque DR Pesch LA | 1975 | Physiolology1975，248，2： | 1 |
| 17 | Tissue distribution of target antigen has a decisive influence on the outcome of adoptive cancer immunotherapy显示文摘 | Roy-Proulx G Labrecque N Perreault C | 2003 | Blood2003，101，2： | 1 |
| 18 | Can a self- management education program for patients with chronic obstructive pulmonary disease improve quality of life? 显示文摘 | LABRECQUE M RABHI K LAURIN C | 2011 | Can Respir J2011，18，5： | 1 |
| 19 | Consumer power : Evolution in the digital age显示文摘 | Labrecque L I | 2013 | Journal of Interactive Marketing2013，27，4： | 1 |
| 20 | Phytoextraction ofheavy metals by two Salicaceae clones in symbiosis witharbuscular mycorrhizal fungi during the second year of a fieldtrial显示文摘 | Bissonnette L St- Amaud M Labrecque M | 2010 | Plant and Soil2010，332，： | 1 |
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