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| 1 | Fiber-enriched diet helps to control symptoms and improves esophageal motility in patients with non-erosive gastroesophageal reflux disease显示文摘AIM To investigate the effect of dietary fiber on symptoms and esophageal function testing parameters in nonerosive gastroesophageal reflux disease(GERD)(NERD) patients.METHODS Thirty-six NERD patients with low(< 20 g/d) dietary fiber intake were enrolled in the study. They were examined with the use of symptom questionnaire(GERD-Q), highresolution esophageal manometry, 24-h esophageal p Himpedance examinations, and food frequency questionnaire before and after 10 d of usual diet supplemented by psyllium 5.0 g TID. Complete data of 30 patients were available to the final analysis. The obtained results were analyzed with the use of non-parametric statistics(Wilcoxon matched pairs test). RESULTS The number of patients experiencing heartburn was less(93.3% at baseline vs 40% at the end of the study, P < 0.001) and the GERD-Q score decreased(mean ± SD: 10.9 ± 1.7 vs 6.0 ± 2.3, P < 0.001) after the treatment period. Minimal resting lower esophageal sphincter(LES) pressure increased from 5.41 ± 10.1 to 11.3 ± 9.4 mm Hg(P = 0.023), but no change in residual LES pressure and mean resting pressure was found. Total number of gastroesophageal refluxes(GER) decreased from 67.9 ± 17.7 to 42.4 ± 13.5(P < 0.001) predominantly by acid and weak acid types of GERs. No significant change in mean esophageal p H and % of time p H < 4 was registered. Maximal reflux time decreased from 10.6 ± 12.0 min to 5.3 ± 3.7 min(P < 0.05). CONCLUSION Fiber-enriched diet led to a significant increase of minimal lower esophageal sphincter resting pressure, a decrease of number of gastroesophageal refluxes, and a decrease of heartburn frequency per week in NERD. | Sergey Morozov Vasily Isakov Mariya Konovalova | 2018 | World Journal of Gastroenterology2018，24，21： | 9 |
| 2 | 强脉冲离子注入中的脉冲能量效应研究显示文摘在脉冲离子束流密度为15-120A/cm2、脉宽为50-150ns、加速电压为150-260kV范围内,在1×104cm-2的低注量水平上,研究了高功率Cn++H+混合离子束注入45号钢样品的强脉冲能量效应.摩擦磨损和微观硬度测量以及SEM和X射线衍射分析表明,上述低注量强脉冲离子束注入可以改变材料表面的微观结构和力学特性,而且强烈依赖于单个脉冲离子束的功率密度和能量密度,在相同离子注量条件下,普通C++H+离子注入对45号钢样品表面微硬度和摩擦系数未见明显影响.直接证明了强脉冲能量效应在离子注入中是相对独立于注入元素掺杂效应的又一可利用的重要效应.基于一维导热模型,讨论了强脉冲能量效应以及脉冲离子束功率密度对离子束材料表面改性的作用。 | 赵渭江 颜莎 乐小云 韩宝玺 薛建明 王宇钢 Remmev G E Opekounov M S Isakov I F Grushin II | 2000 | 核技术2000，23，10： | 8 |
| 3 | World Gastroenterology Organisation Global Guidelines: Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis显示文摘 | Douglas R. LaBrecque Zaigham Abbas Frank Anania Peter Ferenci Aamir G. Khan Khean-Lee Goh Saeed S. Hamid Vasily Isakov Maribel Lizarzabal Manuel M. Pe?aranda Juan F.R. Ramos Shiv Sarin Davor Stimac Alan B.R. Thomson Muhammed Umar Justus Krabshuis Anton Le | 2014 | Journal of Clinical Gastroenterology2014，，6： | 3 |
| 4 | The inverse problem of option pricing显示文摘 | Bouchouev I Isakov V | 1997 | Inverse Problems1997，13，5： | 1 |
| 5 | Resolving local scale emissions for modeling air quality near roadways显示文摘 | COOK R ISAKOV V TOUMA J | 2008 | Journal of the Air & Waste Management Association2008，58，3： | 1 |
| 6 | Directed Fracture of Rocks by Blasting显示文摘 | Isakov A L | 1983 | Soviet Mining Svience1983，19，16： | 1 |
| 7 | Higher modes in simplified inelastic seismic analysis of single column bent viaducts显示文摘 | Isakovic T Fischinger M | 2006 | Earthquake Engineering and Structure Dynamics2006，35，1： | 1 |
| 8 | Protein kinase C (theta) in T cell activation 显示文摘 | Isakov N Ahman A | 2002 | Annu Rev Immunol2002，20，： | 1 |
| 9 | Applicability of pushover methods for the seismic analysis of single-column bent viaducts 显示文摘 | Isakovic T Lazaro M P N Fischinger M | 2008 | Earthquake Engineering and Structural Dynamics2008，，37： | 1 |
| 10 | Increased stability in the continuation of solutions to the Helmholtz equation显示文摘 | Hrycak T Isakov V | | 0，，03： | 1 |
| 11 | Growth and physical properties of a new chiral open-framework crystal for NLO applications: Cesium hydrogen l -malate monohydrate显示文摘 | J.N. Babu Reddy S. Vanishri Ganesh Kamath Suja Elizabeth H.L. Bhat D. Isakov M. Belsley E. de Matos Gomes T.L. Aroso | 2009 | Journal of Crystal Growth2009，，16： | 1 |
| 12 | Identification of the diffusion coefficient in one-dimensional parabolic equation显示文摘 | Isakov V Kindermann S | 2000 | Inverse Problem2000，16，： | 1 |
| 13 | Fluvoxamine treatment of obsessive-compulsive symptoms in schizophrenic patients: an add-on open study显示文摘 | Poyurovsky M Isakov V Hromnikov S | 1999 | Int Clin Psychopharmacol1999，14，2： | 1 |
| 14 | Clinical significance of food antigens blotting capacity by patients with irritable bowel syndrome显示文摘 | Pilipenko VI Burliaeva EA Isakov VA | 2010 | Vopr Pitan2010，79，3： | 1 |
| 15 | A Fast Local Level Set Method for Inverse Gravimetry显示文摘We propose a fast local level set method for the inverse problem of gravimetry.The theoretical foundation for our approach is based on the following uniqueness result:if an open set D is star-shaped or x3-convex with respect to its center of gravity,then its exterior potential uniquely determines the open set D.To achieve this purpose constructively,the first challenge is how to parametrize this open set D as its boundary may have a variety of possible shapes.To describe those different shapes we propose to use a level-set function to parametrize the unknown boundary of this open set.The second challenge is how to deal with the issue of partial data as gravimetric measurements are only made on a part of a given reference domainΩ.To overcome this difficulty,we propose a linear numerical continuation approach based on the single layer representation to find potentials on the boundary of some artificial domain containing the unknown set D.The third challenge is how to speed up the level set inversion process.Based on some features of the underlying inverse gravimetry problem such as the potential density being constant inside the unknown domain,we propose a novel numerical approach which is able to take advantage of these features so that the computational speed is accelerated by an order of magnitude.We carry out numerical experiments for both two-and three-dimensional cases to demonstrate the effectiveness of the new algorithm. | Victor Isakov Shingyu Leung Jianliang Qian | 2011 | Communications in Computational Physics2011，10，9： | 1 |
| 16 | High intensity pulsed ion beam sources and heir dustrial applications 显示文摘 | Remnev G E Isakov I F Tarbokov V A | 1999 | Surface and Coatings Technology1999，114，： | 1 |
| 17 | Effect of fa- tigue on leg kinematics and impact acceleration in long distance running显示文摘 | MIZRAHI J VERBITSKY O ISAKOV E | 2000 | Human Movem Sci2000，19，： | 1 |
| 18 | Character- ization of Near-road Pollutant Gradients Using Path-integrated Optical Remote Sensing显示文摘 | THOMA E D SHORES R C ISAKOV V | 2008 | Journal of the Air & Waste Man- agement Association2008，58，7： | 1 |
| 19 | Reconstructionoptions following breast conservation therapy显示文摘 | Churgin S Isakov R Yetman R | 2008 | Cleve Clin J Med2008，75，： | 1 |
| 20 | X-ray powder diffraction study of malic acid显示文摘 | Isakov A I Kotelnikova E N Kryuchkova L Yu | 2011 | Acta Crystal- lographica Section A: Foundations of Crystallography2011，67，： | 1 |
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