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| 1 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B显示文摘 | Yun–Fan Liaw Edward Gane Nancy Leung Stefan Zeuzem Yuming Wang Ching Lung Lai E. Jenny Heathcote Michael Manns Natalie Bzowej Junqi Niu Steven–Huy Han Seong Gyu Hwang Yilmaz Cakaloglu Myron J. Tong George Papatheodoridis Yagang Chen Nathaniel A. Brown Efs | 2009 | Gastroenterology2009，，2： | 13 |
| 2 | Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease显示文摘AIM To determine if manipulation of dietary advanced glycation end product(AGE), intake affects nonalcoholic fatty liver disease(NAFLD) progression and whether these effects are mediated via RAGE. METHODS Male C57Bl6 mice were fed a high fat, high fructose, high cholesterol(HFHC) diet for 33 wk and compared with animals on normal chow. A third group were given a HFHC diet that was high in AGEs. Another group was given a HFHC diet that was marinated in vinegar to prevent the formation of AGEs. In a second experiment, RAGE KO animals were fed a HFHC diet or a high AGE HFHC diet and compared with wildtype controls. Hepatic biochemistry, histology, picrosirius red morphometry and hepatic mR NA were determined. RESULTS Long-term consumption of the HFHC diet generated significant steatohepatitis and fibrosis after 33 wk. In this model, hepatic 4-hydroxynonenal content(a marker of chronic oxidative stress), hepatocyte ballooning, picrosirius red staining, α-smooth muscle actin and collagen type 1A gene expression were all significantly increased. Increasing the AGE content of the HFHC diet by baking further increased these markers of liver damage, but this was abrogated by pre-marination in acetic acid. In response to the HFHC diet, RAGE-/-animals developed NASH of similar severity to RAGE+/+ animals but were protected from the additional harmful effects of the high AGE containing diet. Studies in isolated Kupffer cells showed that AGEs increase cell proliferation and oxidative stress, providing a likely mechanism through which these compounds contribute to liver injury. CONCLUSION In the HFHC model of NAFLD, manipulation of dietary AGEs modulates liver injury, inflammation, and liver fibrosis via a RAGE dependent pathway. This suggests that pharmacological and dietary strategies targeting the AGE/RAGE pathway could slow the progression of NAFLD. | Christopher Leung Chandana B Herath Zhiyuan Jia Sof Andrikopoulos Bronwyn E Brown Michael J Davies Leni R Rivera John B Furness Josephine M Forbes Peter W Angus | 2016 | World Journal of Gastroenterology2016，22，35： | 7 |
| 3 | SLIPS-TENG: robust triboelectric nanogenerator with optical and charge transparency using a slippery interface显示文摘Energy harvesting devices that prosper in harsh environments are highly demanded in a wide range of applications ranging from wearable and biomedical devices to self-powered and intelligent systems.Particularly,over the past several years,the innovation of triboelectric nanogenerators(TENGs)that efficiently convert ambient kinetic energy of water droplets or wave power to electricity has received growing attention.One of the main bottlenecks for the practical implications of such devices originates from the fast degradation of the physiochemical properties of interfacial materials under harsh environments.To overcome these challenges,here we report the design of a novel slippery lubricant-impregnated porous surface(SLIPS)based TENG,referred to as SLIPS-TENG,which exhibits many distinctive advantages over conventional design including optical transparency,configurability,self-cleaning,flexibility,and power generation stability,in a wide range of working environments.Unexpectedly,the slippery and configurable lubricant layer not only serves as a unique substrate for liquid/droplet transport and optical transmission,but also for efficient charge transfer.Moreover,we show that there exists a critical thickness in the liquid layer,below which the triboelectric effect is almost identical to that without the presence of such a liquid film.Such an intriguing charge transparency behavior is reminiscent of the wetting transparency and van der Waals potential transparency of graphene previously reported,though the fundamental mechanism remains to be elucidated.We envision that the marriage of these two seemingly totally different arenas(SLIPS and TENG)provides a paradigm shift in the design of robust and versatile energy devices that can be used as a clean and longer-lifetime alternative in various working environments. | Wanghuai Xu Xiaofeng Zhou Chonglei Hao Huanxi Zheng Yuan Liu Xiantong Yan Zhengbao Yang Michael Leung Xiao Cheng Zeng Ronald X. Xu Zuankai Wang | 2019 | National Science Review2019，6，3： | 6 |
| 4 | Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn’s and Colitis Epidemiology Study显示文摘 | Siew C. Ng Whitney Tang Jessica Y. Ching May Wong Chung Mo Chow A.J. Hui T.C. Wong Vincent K. Leung Steve W. Tsang Hon Ho Yu Mo Fong Li Ka Kei Ng Michael A. Kamm Corrie Studd Sally Bell Rupert Leong H. Janaka de Silva Anuradhani Kasturiratne M.N.F. Mufeen | 2013 | Gastroenterology2013，，1： | 6 |
| 5 | 二氧化钛光催化分解水制氢技术进展显示文摘简单介绍了二氧化钛光催化分解水制氢的基本原理。综述了加入牺牲剂、碳酸钠、贵金属负载化、金属离子掺杂、阴离子掺杂、染料光敏化、半导体复合以及离子注入等提高二氧化钛光催化制氢的方法,讨论了这几种改性技术的机理以及对提高二氧化钛在可见光下的制氢效率的作用。重点讨论了阴离子掺杂和离子注入技术的机理和研究进展,指出离子注入是目前扩展二氧化钛光响应的最为有效的技术。最后讨论了光催化分解水制氢的氢氧分离问题,并通过与其他制氢技术的对比分析,指出光催化制氢将是通往氢经济的非常有潜力的制氢技术。 | 倪萌 LEUNG Michael SUMATHY K | 2005 | 现代化工2005，25，4： | 4 |
| 6 | 染料敏化分解水制氢技术进展显示文摘介绍了染料敏化分解水制氢的基本原理。综述了染料分子的选取,使用氧化还原调节剂的机理和研究进展。指出染料分子对光谱的吸收特性,激发态染料分子能级与半导体导带的相对位置,染料分子与半导体的吸附情况,表面键合强度直接影响对光子的吸收,电子的注入,从而影响产氢量。此外,I-/I3-作为氧化还原调节剂可有效还原染料分子,实现持续产氢。最后提出了染料敏化分解水制氢的间歇式反应器结构,以及通过选择用于敏化的半导体来提高产氢率的思路。 | 倪萌 LEUNG MICHAEL K H LEUNG DENNIS Y C | 2006 | 电源技术2006，30，10： | 3 |
| 7 | 光催化剂纳米粉体的制备技术显示文摘纳米半导体材料作为光催化剂在环境、能源领域具有广阔的应用前景。光催化剂的制备过程对催化剂的晶体结构有重要的影响,从而影响其光催化活性。本文较系统地综述了国内外对光催化剂纳米粉体制备的研究进展,包括固相法、气相法和湿化学法。对比分析了各种制备技术的优缺点,并对今后的研究方向和应用前景进行了分析。 | 倪萌 Leung Michael K.H. Leung Dennis Y.C. | 2006 | 粉末冶金技术2006，24，5： | 3 |
| 8 | NASPGHAN Practice Guidelines: Diagnosis and Management of Hepatitis C Infection in Infants, Children, and Adolescents显示文摘 | Cara L. Mack Regino P. Gonzalez-Peralta Nitika Gupta Daniel Leung Michael R. Narkewicz Eve A. Roberts Philip Rosenthal Kathleen B. Schwarz | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，6： | 2 |
| 9 | 染料敏化太阳电池纳米结构对输出特性的影响显示文摘根据电子在半导体中的扩散方程,对纳米TiO2染料光敏化太阳电池(DSSC)的输出特性(J-V)进行了研究。多孔薄膜TiO2孔隙率(P)直接影响敏化电极光吸收系数(a)以及电子扩散系数(D),将P与a及D的关系式代入扩散方程,得到了电极纳米结构(孔隙率)对电池输出特性(J-V)影响的计算模型。在光电极孔隙率的实验范围(0.41~0.71),进行了模型分析。研究表明,在孔隙率0.41~0.71的范围内,开路电压(VOC)随P值增大基本保持不变,而短路电流(ISC)则随P值增大而明显减小,因此电池的最大输出功率减小,为获得最大输出功率,P应该控制在0.41~0.5。数值模拟与实验数据进行比较,两者符合良好,从而验证了所建立的模型。 | 倪萌 LEUNG Michael | 2006 | 电源技术2006，30，9： | 2 |
| 10 | Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study显示文摘 | Hongjie Yu Joseph T Wu Benjamin J Cowling Qiaohong Liao Vicky J Fang Sheng Zhou Peng Wu Hang Zhou Eric H Y Lau Danhuai Guo Michael Y Ni Zhibin Peng Luzhao Feng Hui Jiang Huiming Luo Qun Li Zijian Feng Yu Wang Weizhong Yang Gabriel M Leung | 2013 | The Lancet2013，，： | 2 |
| 11 | 基底对染料敏化太阳电池J-U特性的影响显示文摘根据肖特基理论和电子在半导体中的扩散理论,建立了模拟染料敏化太阳电池(DSSC)J-U特性的理论模型,分析了透明导电氧化物(TCO)基底材料的选择对J-U特性的影响。研究表明,TCO与TiO2界面形成的肖特基结对DSSC开路电压(UOC)和短路电流密度(JSC)没有影响,但对填充因子(Fillfactor)有较大影响。当TiO2/TCO的肖特基势垒(Eb)大于0.6eV时,DSSC的最大功率输出值随Eb的增大而明显降低。模型结果与文献报道的实验结果一致。该模型研究为DSSC基底材料的选取提供了理论依据,并适用于除TiO2之外的其他半导体材料。 | 倪萌 LEUNG Michael | 2006 | 电源技术2006，30，8： | 2 |
| 12 | Single-Incision Surgery Has Higher Cost with Equivalent Pain and Quality-of-Life Scores Compared with Multiple-Incision Laparoscopic Cholecystectomy: A Prospective Randomized Blinded Comparison显示文摘 | Dennis Leung Amy K. Yetasook JoAnn Carbray Zeeshan Butt Yumiko Hoeger Woody Denham Ermilo Barrera Michael B. Ujiki | 2012 | Journal of the American College of Surgeons2012，，5： | 2 |
| 13 | An overview of hydrogen production from biomass显示文摘 | Meng Ni Dennis Y C Leung Michael K H Leung Sumathy K | 2006 | Fuel Processing Technology2006，，87： | 1 |
| 14 | Use of miniscrews and miniplates in orthodontics 显示文摘 | Leung Michael Tat-Chi Lee Tony Cheuk-Kit Rabie A | 2008 | J Oral Maxillofac Surg2008，66，： | 1 |
| 15 | Effect of carbon starvation on p-nitrophenol degradation by a Moraxella strain in buffer and river water显示文摘 | Kam Tin Leung Michael Moore Hung Lee | 2005 | Microbiology Ecology2005，51，2： | 1 |
| 16 | Solar photocatalytic degradation of gaseous formaldehyde by sol-gel TiO2 thin fihn for enhancement of indoor air quality显示文摘 | Ching W H Leung Michael Leung Dennis Y C | 2004 | Solar Energy2004，77，2： | 1 |
| 17 | Parametric study of solid oxide steam eletrolyzer for hydrogen production显示文摘 | Meng Ni Michael K H Leung Dennis Y C Leung | | 0，，： | 1 |
| 18 | Serum HE4 as a prognostic marker in endometrial cancer — A population based study显示文摘 | Donal J. Brennan Andreas Hackethal Alex M. Metcalf Jermaine Coward Kaltin Ferguson Martin K. Oehler Michael A. Quinn Monika Janda Yee Leung Michael Freemantle Penelope M. Webb Amanda B. Spurdle Andreas Obermair | 2014 | Gynecologic Oncology2014，，1： | 1 |
| 19 | 2-Year GLOBE Trial Results: Telbivudine Is Superior to Lamivudine in Patients With Chronic Hepatitis B显示文摘 | Yun–Fan Liaw Edward Gane Nancy Leung Stefan Zeuzem Yuming Wang Ching Lung Lai E. Jenny Heathcote Michael Manns Natalie Bzowej Junqi Niu Steven–Huy Han Seong Gyu Hwang Yilmaz Cakaloglu Myron J. Tong George Papatheodoridis Yagang Chen Nathaniel A. Brown Efs | 2009 | Gastroenterology2009，，2： | 1 |
| 20 | Endo-Laparoscopic Colectomy Without Mini-Laparotomy for Left-Sided Colonic Tumors显示文摘 | Hester Y. S. Cheung Alex L. H. Leung C. C. Chung Dennis C. K. Ng Michael K. W. Li | 2009 | World Journal of Surgery2009，，6： | 1 |
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