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| 1 | Characterisation and risk assessment of venous thromboembolism in gastrointestinal cancers显示文摘AIM To characterise venous thromboembolism(VTE) in gastrointestinal cancer and assess the clinical utility of risk stratification scoring. METHODS We performed a retrospective analysis using electronic patient records of 910 gastro-oesophageal(GO) cancer and 1299 colorectal cancer(CRC) patients referred to a tertiary cancer centre to identify the incidence of VTE, its relationship to chemotherapy and impact on survival.VTE risk scores were calculated using the Khorana index. Patients were classified as low risk(0 points), intermediate risk(1 to 2 points) or high risk(3 points). Data was analysed to determine the sensitivity of the Khorana score to predict VTE. RESULTS The incidence of VTE was 8.9% for CRC patients and 9.7% for GO cancer patients. Pulmonary emboli(PE) were more common in advanced than in localised CRC(50% vs 21% of events respectively) and lower limb deep vein thrombosis(DVT) were more common in localised than in advanced CRC(62% vs 39% of events respectively). The median time to VTE from cancer diagnosis was 8.3 mo for CRC patients compared to 6.7 mo in GO cancer. In localised CRC median time to VTE was 7.1 mo compared with 10.1 mo in advanced CRC. In contrast in GO cancer, the median time to VTE was 12.5 mo in localised disease and 6.8 mo in advanced disease. No survival difference was seen between patients with and without VTE in this cohort. The majority of patients with CRC in whom VTE was diagnosed had low or intermediate Khorana risk score(94% for localised and 97% in advanced CRC). In GO cancer, all patients scored either intermediate or high risk due to the primary site demonstrating a limitation of the risk assessment score in discriminating high and low risk patients with GO cancers. Additional risk factors were identified in this cohort including surgery, chemotherapy or hospital admission. Overall, 81% of patients with CRC and 77% of patients with GO cancer had one or more of these factors within 4 wk prior to diagnosis VTE. These should be factored into clinical risk assessment scores. CONCLUSION The Khorana score has low sensitivity for thrombotic events in CRC and cannot discriminate low risk patients in high risk cancer sites such as GO cancer. | Robert L Metcalf Eamon Al-Hadithi Nicholas Hopley Thomas Henry Clare Hodgson Antony McGurk Wasat Mansoor Jurjees Hasan | 2017 | World Journal of Gastrointestinal Oncology2017，9，9： | 10 |
| 2 | 聚氯乙烯材料的热分解特性的研究(英文)显示文摘用热重法研究了聚氯乙烯装饰材料在不同的加热速率、不同的气氛下的热分解特性。用最小二乘法计算了聚氯乙烯材料在脱氯化氢反应的动力学参数,分解反应的活化能和反应级数。 | 王正洲 王颖 Edwin Metcalfe | 1998 | 中国科学技术大学学报1998，28，5： | 8 |
| 3 | The Jinshajiang suture zone: tectono-stratigraphic subdivision and revision of age显示文摘Integrated study of rock assemblage, tectonic setting, geochemical feature, fossil contained and isotopic geochronology on the metamorphic mixed bodies, exposed in the Jinshajiang suture zone, suggests that one informal lithostratigraphic unit, the Eaqing Complex, and three tec-tono-stratigraphic units, the Jinshajiang ophiolitic melange, the Gajinxueshan Group and the Zhongxinrong Group, can be recognized there. It is first pointed out that the redefined Eaqing Complex might represent the Meso- to Neo-Proterozoic remnant metamorphic basement or mi-crocontinental fragment in the Jinshajiang area. The original rocks of it should be older than (1627 ±192) Ma based on the geochronological study. The zircon U-Pb age of plagiogranites within the Jinshajiang ophiolitic assemblage is dated for the first time at (294±3) Ma and (340±3) Ma respectively. The Jinshajiang ophiolite is approximately equivalent to the Ailaoshan ophiolite in the formation age, covering the interval from the Late Devonian to the | 汪啸风 lan Metcalfe 简平 何龙清 王传尚 | 2000 | Science China Earth Sciences2000，43，1： | 4 |
| 4 | Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: Follow-up for up to 28 years显示文摘 | Martin Prince Amanda Chetwynd Wendy Newman Jane V. Metcalf Oliver F.W. James | 2002 | Gastroenterology2002，，4： | 2 |
| 5 | The immobilization of high level radioactive wastes using ceramics and glasses显示文摘 | I. W Donald B. L Metcalfe R. N. J Taylor | 1997 | Journal of Materials Science1997，，22： | 2 |
| 6 | How much liver resection is too much?显示文摘 | Emma J. Mullin Matthew S. Metcalfe Guy J. Maddern | 2005 | The American Journal of Surgery2005，，1： | 2 |
| 7 | Elevation of Carbohydrate Antigen 19.9 in Benign Hepatobiliary Conditions and Its Correlation with Serum Bilirubin Concentration显示文摘 | S. L. Ong A. Sachdeva G. Garcea G. Gravante M. S. Metcalfe D. M. Lloyd D. P. Berry A. R. Dennison | 2008 | Digestive Diseases and Sciences2008，，12： | 2 |
| 8 | Satisfaction with breast reconstruction in women with bilateral prophylactic mastectomy: a descriptive study显示文摘 | METCALFE K A SEMPLE J L NAROD S A | 2004 | Plast Reconstr Surg2004，114，2： | 2 |
| 9 | Properties of diamond tool binders with fine carbonyl Ni powder additions显示文摘Fine Ni powder is often added to Co and bronze-based metal binder powders for diamond tool segments.Ni is a lower cost substitute for extra-fine Co powder and increases the toughness of Co-Fe diamond binders at the expense of lower hardness and bend strength.In bronze-based diamond binder segments,Ni increases hardness and yield strength.Several grades of Ni powder are used commercially with both Co and bronze-based diamond binders.This paper compares properties of diamond binders containing carbonyl Ni powders including standard Inco(?) T255,T123 PM and T 110 PM.Binder materials were made by ball milling or dry mixing of the fine carbonyl Ni and Fe powders with either XF Co or air atomized bronze(90/10 Cu/Sn) powders.Co-based powder blends were hot pressed at 20~35 MPa and 700℃to 900℃.Bronze-based powder blends were cold pressed and sintered at 840℃.Apparent density,apparent hardness and bend strength(TRS) were compared for different binder compositions and processing conditions. | Stephenson T F Korotkin M Metcalfe S | 2008 | 金刚石与磨料磨具工程2008，28，S1： | 2 |
| 10 | Urea recycling in sheep:Effects of intake 显示文摘 | Sarraseca A E Milne M J Metcalf | 1998 | Br J Nutrition1998，79，： | 1 |
| 11 | Report on the 12th International Society of Blood Transfusion platelet immunology workshop显示文摘 | Bessos H Wilson DWL Metcalfe P | 2005 | Vox Sanguinis2005，89，： | 1 |
| 12 | Severe complications of hysterectomy:the VALUE study显示文摘 | McPherson K Metcalfe MA Herbert A | 2004 | BJOG2004，111，7： | 1 |
| 13 | Characterization and identification of a porcine small intestine mucus receptor for the K88ab fimbrial adhesion显示文摘 | Metcalfe JW Krogfelt KA Krivan HC | 1991 | Infection and Immunity1991，59，1： | 1 |
| 14 | Permian tectonic framework and palaeogeography of SE Asia显示文摘 | Metcalfe I | 2002 | JAsian Earth Sci2002，20，6： | 1 |
| 15 | Evolutionary economics and technology pol- icy显示文摘 | Metcalfe J S | 1994 | Economic Journal1994，104，425： | 1 |
| 16 | A Hot/cool-system Analysis of Delay of Gratification:Dynamics of Willpower显示文摘 | Metcalfe J Mischel W | 1999 | Psychology Review1999，，106： | 1 |
| 17 | A Theoretical Approach to the Construction of Technological Output Indicators 显示文摘 | Saviotti P P Metcalfe J S | 1984 | Re- search Policy1984，13，3： | 1 |
| 18 | Electrospray ionization mass spectrometry of ginsenosides 显示文摘 | Miao XS Metcalfe CD Hao CY | 2002 | J Mass Spectrom2002，37，5： | 1 |
| 19 | Processing-related fracture origins:Ⅱ agglomerate motion and crack-like internal surface caused by differential sintering 显示文摘 | LANG F F METCALF M | 1983 | J Am Ceram Soc1983，66，： | 1 |
| 20 | Natural history of early primary biliary cirrhosis 显示文摘 | Metcalf JV Mitchison HC Palmer JM | 1996 | Lancet1996，348，： | 1 |
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