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| 1 | Injectable hydrogels for cartilage and bone tissue engineering显示文摘Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture scaffolds in cartilage and bone tissue engineering, owing to their high water content, similarity to the natural extracellular matrix(ECM), porous framework for cell transplantation and proliferation, minimal invasive properties, and ability to match irregular defects. In this review, we describe the selection of appropriate biomaterials and fabrication methods to prepare novel injectable hydrogels for cartilage and bone tissue engineering. In addition, the biology of cartilage and the bony ECM is also summarized. Finally, future perspectives for injectable hydrogels in cartilage and bone tissue engineering are discussed. | Mei Liu Xin Zeng Chao Ma Huan Yi Zeeshan Ali Xianbo Mou Song Li Yan Deng Nongyue He | 2017 | Bone Research2017，5，2： | 54 |
| 2 | Thymoma: current diagnosis and treatment显示文摘 | Frank C. Detterbeck Ahmad Zeeshan | 2013 | Chinese Medical Journal2013，，11： | 39 |
| 3 | 增产丙烯技术研究进展显示文摘对由石油路线和非石油路线增产丙烯技术所涉及到的工艺过程进行了综述,指出近期丙烯生产仍将以石油路线为主,非石油路线为辅。从反应机理、热力学分析可知,采用择形分子筛催化剂在较低反应温度(400~600℃)下的烃类裂解制丙烯工艺可得到高的丙烯收率,是目前由石油路线增产丙烯的主要发展方向,特别是采用择形分子筛催化剂的多产丙烯流化催化裂化技术和低碳烯烃转化技术相耦合的工艺;而非石油路线中的甲醇/二甲醚转化制丙烯技术与低碳烯烃转化技术相耦合的工艺将是我国增产丙烯的另一重要途径。 | 魏飞 汤效平 周华群 Zeeshan Nawaz | 2008 | 石油化工2008，37，10： | 28 |
| 4 | Geometric Mean Decomposition Based Hybrid Precoding for Millimeter-Wave Massive MIMO显示文摘Hybrid precoding can reduce the number of required radio frequency(RF)chains in millimeter-Wave(mmWave) massive MIMO systems. However, existing hybrid precoding based on singular value decomposition(SVD) requires the complicated bit allocation to match the different signal-to-noise-ratios(SNRs) of different sub-channels. In this paper,we propose a geometric mean decomposition(GMD)-based hybrid precoding to avoid the complicated bit allocation. Specifically,we seek a pair of analog and digital precoders sufficiently close to the unconstrained fully digital GMD precoder. To achieve this, we fix the analog precoder to design the digital precoder, and vice versa. The analog precoder is designed based on the orthogonal matching pursuit(OMP) algorithm, while GMD is used to obtain the digital precoder. Simulations show that the proposed GMD-based hybrid precoding achieves better performance than the conventional SVD-based hybrid precoding with only a slight increase in complexity. | Tian Xie Linglong Dai Xinyu Gao Muhammad Zeeshan Shakir Jianjun Li | 2018 | China Communications2018，15，5： | 17 |
| 5 | In situ Synthesis of SAPO-34 Zeolites in Kaolin Microspheres for a Fluidized Methanol or Dimethyl Ether to Olefins Process显示文摘SAPO-34 zeolite is considered to be an effective catalyst for methanol or dimethyl ether conversion to olefins. In this study,we developed the in situ synthesis technology to prepare SAPO-34 zeolite in kaolin micro-spheres as a catalyst for fluidized methanol or dimethyl ether to olefins process. The silicoaluminophosphate zeolite was first time reported to be synthesized in kaolin microspheres. The SAPO-34 content of synthesized catalyst was about 22% as measured by three different quantitative methods(micropore area,X-ray fluorescence and energy dispersive spectroscopy element analysis) . Most of the SAPO-34 zeolites were in nanoscale size and distributed uniformly inside the spheres. The catalytic performance was evaluated in fixed bed and fluidized bed reactors. Compared with the conventional spray-dry catalyst,SAPO/kaolin catalyst showed superior catalytic activities,bet-ter olefin selectivities(up to 94%,exclusive coke) ,and very good hydrothermal stability. The in situ synthesis of SAPO-34 in kaolin microspheres is a facile and economically feasible way to prepare more effective catalyst for fluidized MTO/DTO(methanol to olefins/dimethyl ether to olefins) process. | ZHU Jie CUI Yu NAWAZ Zeeshan WANG Yao WEI Fei | 2010 | Chinese Journal of Chemical Engineering2010，18，6： | 13 |
| 6 | Big Earth Data science:an information framework for a sustainable planet显示文摘The digital transformation of our society coupled with the increasing exploitation of natural resources makes sustainability challenges more complex and dynamic than ever before.These changes will unlikely stop or even decelerate in the near future.There is an urgent need for a new scientific approach and an advanced form of evidence-based decisionmaking towards the benefit of society,the economy,and the environment.To understand the impacts and interrelationships between humans as a society and natural Earth system processes,we propose a new engineering discipline,Big Earth Data science.This science is called to provide the methodologies and tools to generate knowledge from diverse,numerous,and complex data sources necessary to ensure a sustainable human society essential for the preservation of planet Earth.Big Earth Data science aims at utilizing data from Earth observation and social sensing and develop theories for understanding the mechanisms of how such a social-physical system operates and evolves.The manuscript introduces the universe of discourse characterizing this new science,its foundational paradigms and methodologies,and a possible technological framework to be implemented by applying an ecosystem approach.CASEarth and GEOSS are presented as examples of international implementation attempts.Conclusions discuss important challenges and collaboration opportunities. | Huadong Guo Stefano Nativi Dong Liang Max Craglia Lizhe Wang Sven Schade Christina Corban Guojin He Martino Pesaresi Jianhui Li Zeeshan Shirazi Jie Liu Alessandro Annoni | 2020 | International Journal of Digital Earth2020，13，7： | 12 |
| 7 | Arabidopsis ABF3 and ABF4 Transcription Factors Act with the NF-YC Complex to Regulate SOC1 Expression and Mediate Drought-Accelerated Flowering显示文摘The drought-escape response accelerates flowering in response to drought stress, allowing plants to adaptively shorten their life cycles. Abscisic acid (ABA) mediates plant responses to drought, but the role of ABA-responsive element (ABRE)-binding factors (ABFs) in the drought-escape response is poorly understood. Here, we show that Arabidopsis thaliana ABF3 and ABF4 regulate flowering in response to drought through transcriptional regulation of the floral integrator SUPPRESSOR OF OVEREXPRESSION OF CONSTANS1 (SOC1). The abf3 abf4 mutant displayed ABA-insensitive late flowering under long-day conditions. Ectopic expression of ABF3 or ABF4 in the vasculature, but not in the shoot apex, induced early flowering, whereas expression of ABF3 fused with the SRDX transcript!onal repressor domain delayed flowering. We identified SOC1 as a direct downstream target of ABF3/4, and found that SOC1 mRNA levels were lower in abf3 abf4 than in wild-type plants. Moreover, induction of SOC1 by ABA was hampered in abf3 abf4 mutants. ABF3 and ABF4 were enriched at the -1028- to -657-bp region of the SOC1 promoter, which does not contain canonical ABF-ABRE-binding motifs but has the NF-Y binding element. We found that ABF3 and ABF4 interact with nuclear factor Y subunit C (NF-YC) 3/4/9 in vitro and in planta, and induction of SOC1 by ABA was hampered in nf-yc3 yc4 yc9 mutants. Interestingly, the abf3 abf4, nf-yc3 yc4 yc9, and sod mutants displayed a reduced drought-escape response. Taken together, these results suggest that ABF3 and ABF4 act with NF-YCs to promote flowering by inducing SOC1 transcription under drought conditions . This mechanism might contribute to adaptation by enabling plants to complete their life cycles under drought stress. | Keumbi Hwang Hendry Susila Zeeshan Nasim Ji-Yul Jung Ji Hoon Ahn | 2019 | Molecular Plant2019，12，4： | 12 |
| 8 | Measuring Similarity of Academic Articles with Semantic Profile and Joint Word Embedding显示文摘Long-document semantic measurement has great significance in many applications such as semantic searchs, plagiarism detection, and automatic technical surveys. However, research efforts have mainly focused on the semantic similarity of short texts. Document-level semantic measurement remains an open issue due to problems such as the omission of background knowledge and topic transition. In this paper, we propose a novel semantic matching method for long documents in the academic domain. To accurately represent the general meaning of an academic article, we construct a semantic profile in which key semantic elements such as the research purpose, methodology, and domain are included and enriched. As such, we can obtain the overall semantic similarity of two papers by computing the distance between their profiles. The distances between the concepts of two different semantic profiles are measured by word vectors. To improve the semantic representation quality of word vectors, we propose a joint word-embedding model for incorporating a domain-specific semantic relation constraint into the traditional context constraint. Our experimental results demonstrate that, in the measurement of document semantic similarity, our approach achieves substantial improvement over state-of-the-art methods, and our joint word-embedding model produces significantly better word representations than traditional word-embedding models. | Ming Liu Bo Lang Zepeng Gu Ahmed Zeeshan | 2017 | Tsinghua Science and Technology2017，22，6： | 9 |
| 9 | Investigation of ZrO2 nanoparticles concentration and processing time effect on the localized PEO coatings formed on AZ91 alloy显示文摘AZ91 Mg alloy was treated through a new localized PEO(Plasma Electrolytic Oxidation)coating approach,using electrolyte solutions with varying ZrO2 nanoparticles concentration(2-8 g/L)and processing times.With increase in the ZrO2 concentration,several microstructural changes were observed including;formation of cluster-type structure,damage to the inner layers(∼30 min)and sealing of defects.Corrosion analysis of the final coatings was carried out using potentiodynamic polarization,electrochemical impedance spectroscopy and post-corrosion analysis.It was explored that highest corrosion resistance(Rp∼81.17 kΩcm^2)of the coatings was obtained for ZrO2∼2 g/L.However,higher concentration of the ZrO2 nanoparticles caused weak crystalline coating structure,due to unstable and lower intensity discharges,thus failed to offer high corrosion resistance performance. | Zeeshan Ur Rehman Dongjin Choi | 2019 | Journal of Magnesium and Alloys2019，7，4： | 9 |
| 10 | Farmers' Perception and Awareness and Factors Affecting Awareness of Farmers Regarding Crop Insurance as a Risk Coping Mechanism Evidence from Pakistan显示文摘This study has been conducted in three districts of Punjab Province namely, Dera Ghazi Khan, Rajan Pur and Bahawalpur of Pakistan. The study showed the results of a survey of 300 farmers which was organized to assess awareness level of farmers regarding crop insurance, factors affecting the awareness level among farmers and the perception of farmers about crop insurance. Based on exploratory research work upon the responses of farmers, the average and standard deviation were calculated. Probit model was applied to explore the factors affecting the awareness level of farmers. SPSS was used for the analysis of the collected data. The results revealed that out of 300 farmers, 184 farmers were aware with crop insurance and rests of the 116 farmers were not aware. Banks and E-media were found to be the two most important sources of the awareness for the respondent farmers. In the study area, the climatic risks were reported as the most severe risks faced by the farmers. The results also revealed the existence of negative perceptions of the farmers about crop insurance i.e. farmers perceived crop insurance as a kind of tax and they believed premium was so high that it was out of range of poor farmers and only large scale farmers could afford it. Results obtained by applying Probit model revealed that 'education' and 'previously availed agricultural credit' were the two most important factors which affected the awareness of the farmers regarding crop insurance. | Sidra Ghazanfar Zhang Qi-wen Muhammad Abdullah Zeeshan Ahmad Majid Lateef | 2015 | Journal of Northeast Agricultural University(English Edition)2015，22，1： | 9 |
| 11 | Multidisciplinary Design and Optimization of Multistage Ground-launched Boost Phase Interceptor Using Hybrid Search Algorithm显示文摘This article proposes a multidisciplinary design and optimization (MDO) strategy for the conceptual design of a multistage ground-based interceptor (GBI) using hybrid optimization algorithm,which associates genetic algorithm (GA) as a global optimizer with sequential quadratic programming (SQP) as a local optimizer.The interceptor is comprised of a three-stage solid propulsion system for an exoatmospheric boost phase intercept (BPI).The interceptor's duty is to deliver a kinetic kill vehicle (KKV) to the optimal position in space to accomplish the mission of intercept.The modules for propulsion,aerodynamics,mass properties and flight dynamics are integrated to produce a high fidelity model of the entire vehicle.The propulsion module comprises of solid rocket motor (SRM) grain design,nozzle geometry design and performance prediction analysis.Internal ballistics and performance prediction parameters are calculated by using lumped parameter method.The design objective is to minimize the gross lift off mass (GLOM) of the interceptor under the mission constraints and performance objectives.The proposed design and optimization methodology provide designers with an efficient and powerful approach in computation during designing interceptor systems. | Qasim Zeeshan Khurram Nisar Ali Kamran Amer Rafique | 2010 | Chinese Journal of Aeronautics2010，23，2： | 8 |
| 12 | Addition of simvastatin to carvedilol non responders: A new pharmacological therapy for treatment of portal hypertension显示文摘AIM To determine whether addition of simvastatin could be an important pharmacological rescue therapy for carvedilol non-responders. METHODS One hundred and two consecutive patients of cirrhosis of liver with significant portal hypertension were included. Hepatic venous pressure gradient(HVPG) was measured at the base line and after proper optimization of dose; chronic response was assessed at 3 mo. Carvedilol non-responders were given simvastatin 20 mg per day(increased to 40 mg per day at day 15). Carvedilol plus simvastatin was continued for 1 mo and hemodynamic response was again measured at 1 mo.RESULTS A total of 102 patients with mean age of 58.3 ± 6.6 years were included. Mean baseline HVPG was 16.75 ± 2.12 mmH g and after optimization of dose and reassessment of HVPG at 3 mo, mean reduction of HVPG from baseline was 5.5 ± 1.7 mm Hg and 2.8 ± 1.6 mm Hg among responders and non-responders respectively(P < 0.001). Addition of simvastatin to carvedilol non-responders resulted in significant response in 16 patients(42.1%) and thus overall response with carvedilol and carvedilol plus simvastatin was seen in 78 patients(80%). Two patients were removed in chronic protocol study with carvedilol and three patients were removed in carvedilol plus simvastatin study due to side effects.CONCLUSION Addition of simvastatin to carvedilol non-responders may prove to be an excellent rescue therapy in patients with portal hypertension. | Zeeshan Ahmad Wani Sonmoon Mohapatra Afaq Ahmad Khan Ashutosh Mohapatra Ghulam Nabi Yatoo | 2017 | World Journal of Hepatology2017，9，5： | 8 |
| 13 | 地球大数据监测和评估可持续发展指标显示文摘联合国可持续发展目标(SDGs)涵盖经济、社会、环境三大领域,为各国全面转向可持续发展指明了方向.然而,数据缺失、发展不均衡、目标间关联且相互制约等问题阻碍了SDGs实现.地球大数据为SDGs实现提供了创新解决方案,其宏观、动态监测能力可为SDGs进展评估研究提供关键支撑.中国科学院战略性先导科技专项“地球大数据科学工程”围绕6个SDGs及其指标进行研究,取得了一系列成果.本文重点介绍了地球大数据在可持续发展指标监测和评估中的研究进展,包括模型和算法、决策支持分析方法、数据产品等,并综合分析了在2010~2020年期间6个SDGs的动态变化情况,发现中国在6个SDGs方面正稳步推进,近年来改善幅度显著. | 郭华东 梁栋 孙中昶 陈方 王心源 李俊生 朱丽 边金虎 魏延强 黄磊 陈玉 彭代亮 李晓松 卢善龙 刘洁 Zeeshan Shirazi | 2022 | Science Bulletin2022，67，17： | 7 |
| 14 | DOA Estimation Algorithm Based on Adaptive Filtering in Spatial Domain显示文摘In this paper, a novel DOA estimation methodology based upon the technology of adaptive nulling antenna is proposed. Initially, the nulling antenna obtains the weight vector by LMS algorithm and power inversion criterion.Afterwards, reciprocal of the antenna pattern is defined as the spatial spectrum and the extracted peak values are corresponded to the estimated DOA. Through observation of the spectrum and data analysis of variable steps and SNRs, the simulation results demonstrate that the proposed method can estimate DOA above board. Furthermore, the estimation error of the proposed technique is directly proportional to step size and is inversely proportional to SNR. Unlike the existing MUSIC algorithm, the proposed algorithm has less computational complexity as it eliminates the need of estimating the number of signals and the eigenvalue decomposition of covariance matrix. Also it outperforms MUSIC algorithm, the recently proposed MUSIC-Like algorithm and classical methods by achieving better resolution with narrow width of peaks. | Hao Zeng Zeeshan Ahmad Jianwen Zhou Qiushi Wang Ya Wang | 2016 | China Communications2016，13，12： | 7 |
| 15 | Innovative approaches to the Sustainable Development Goals using Big Earth Data显示文摘A persistent challenge for the Sustainable Development Goals(SDGs)has been a lack of data for indicators to assess progress towards each goal and varying capacities among nations to con-duct these assessments.Rapid developments in big data,however,are facilitating a global approach to the SDGs.Tools and data products are emerging that can be extended to and leveraged by nations that do not yet have the capacity to measure SDG indica-tors.Big Earth Data,a special class of big data,integrates multisource data within a geographic context,utilizing the principles and methodologies of the established literature on big data science,applied specifically to Earth system science.This paper discusses the research challenges related to Big Earth Data and the concerted efforts and investments required to make and mea-sure progress towards the SDGs.As an example,the Big Earth Data Science Engineering Program(CASEarth)of the Chinese Academy of Sciences is presented along with other case studies on Big Earth Data in support of the SDGs.Lastly,the paper proposes future priorities for developments in Big Earth Data,such as human resource capacity,digital infrastructure,interoperability,and envir-onmental considerations. | Huadong Guo Dong Liang Fang Chen Zeeshan Shirazi | 2021 | Big Earth Data2021，5，3： | 7 |
| 16 | 不同结构SAPO-34催化剂上1-己烯催化裂解制丙烯(英文)显示文摘制备了100%SAPO-34,30%SAPO-34和介孔-SAPO-34三种不同类型的SAPO-34分子筛催化剂,并采用氮吸附、扫描电镜、X射线衍射和红外光谱等方法对催化剂进行了表征.三种催化剂的微孔结构、比表面积和总酸量近似,但具有不同的催化剂组成和次级结构.以1-己烯裂解为模型反应考察了三种催化剂的催化活性.对于30%SAPO-34催化剂,由于添加了粘结剂,其外表面酸性和扩散性能下降,导致催化活性降低;100% SAPO-34催化剂则具有较好的催化性能;介孔SAPO-34催化剂次级结构的存在使其失活较慢,从而提高了原料的转化率.详细讨论了1-己烯催化裂解制丙烯的活性和选择性曲线,以进一步说明催化剂组成和结构的影响. | Zeeshan NAWAZ 汤效平 朱杰 魏飞 Shahid NAVEED | 2009 | 催化学报2009，30，10： | 5 |
| 17 | Pharmacotherapy for the management of achalasia: Current status, challenges and future directions显示文摘This article reviews currently available pharmacological options available for the treatment of achalasia, with a special focus on the role of botulinum toxin(BT) injection due to its superior therapeutic effect and side effect profile. The discussion on BT includes the role of different BT serotypes, better pharmacological formulations, improved BT injection techniques, the use of sprouting inhibitors, designer recombinant BT formulations and alternative substances used in endoscopic injections. The large body of ongoing research into achalasia and BT may provide a stronger role for BT injection as a form of minimally invasive, cost effective and efficacious form of therapy for patients with achalasia. The article also explores current issues and future research avenues that may prove beneficial in improving the efficacy of pharmacological treatment approaches in patients with achalasia. | Ammar Nassri Zeeshan Ramzan | 2015 | World Journal of Gastrointestinal Pharmacology and Therapeutics2015，6，4： | 5 |
| 18 | Comparison of mixing layer height inversion algorithms using lidar and a pollution case study in Baoding, China显示文摘Beijing–Tianjin–Hebei area is suffering from atmospheric pollution from a long time. The understanding of the air pollution mechanism is of great importance for officials to design strategies for the environmental governance. Mixing layer height(MLH) is a key factor influencing the diffusion of air pollutants. It plays an important role on the evolution of heavy pollution events. Light detection and ranging(lidar), is an effective remote-sensing tool, which can retrieve high spatial and temporal evolution process within mixing layer(ML), especially the variation of MLH. There are many methods to retrieve MLH, but each method has its own applicable limitations. The Mie-lidar data in Beijing was firstly used to compare three different algorithms which are widely used under different pollution levels.We find that the multi-layer structure near surface may cause errors in the detection of mixing layer. The MLH retrieved based on image edge detection was better than another two methods especially under heavy polluted episode. Then we applied this method to investigate the evolution of the mixing layer height during a pollution episode in December2016. MLH at Gucheng county showed the positive correlation with the concentration of particulate matters during the start of this pollution episode. The elevated pollution level in Gucheng was not associated with MLH's decrease, and the significantly increased particulate matters raised the boundary layer, which trapped the pollutants near the surface. | Xiangguang Ji Cheng Liu Zhouqing Xie Qihou Hu Yunsheng Dong Guangqiang Fan Tianshu Zhang Chengzhi Xing Zhuang Wang Zeeshan Javed Jianguo Liu | 2019 | Journal of Environmental Sciences2019，31，5： | 5 |
| 19 | DCC/DMAP mediated esterification of hydroxy and non-hydroxy olefinic fatty acids with β-sitosterol:In vitro antimicrobial activity显示文摘A new series of fatty alkenoates were synthesized using an appropriate synthetic route involving DCC and DMAP as catalysts. Compounds were characterized by their spectral data. All the synthesized compounds were evaluated for their in vitro antimicrobial activity. The minimum inhibitory concentration (MIC), minimum bacterial concentration (MBC) and minimum fungicidal concentration (MFC) were determined for test compounds as well as for reference standards. Among the compounds tested, compounds having hydroxy group at the fatty acid chain showed the most potent antibacterial as well as antifungal activities. | Nida N.Farshori Mudasir R.Banday Zeeshan Zahoor Abdul Rauf | 2010 | Chinese Chemical Letters2010，21，6： | 5 |
| 20 | Simultaneous extraction of DNA and RNA from Escherichia coli BL 21 based on silica-coated magnetic nanoparticles显示文摘The extraction of nucleic acid is recognized as one of the most essential steps in molecular biology for initiating other downstream applications such as sequencing, amplification, hybridization, and cloning. Many commercial kits and methods are currently available that allow the extraction of only one type of nucleic acids-DNA or RNA. However, in parallel clinical detection of several diseases, a method for simultaneous extraction of both DNA and RNA from the same source is needed in such cases. In this study, a method for simultaneous extraction of DNA and RNA from bacteria based on magnetic nanoparticles(MNPs) was described. Lysis buffers were prepared to help the nucleic acid released and adsorbed to MNPs. Then, two washing buffers were used to remove the contamination of proteins and carbohydrates. The nucleic acids were finally eluted by Deoxyribonuclease(DNase) and Ribonucleases(RNase) free water. Different factors which might affect the purification of the nucleic acid were investigated, and the quantity and quality parameters of the nucleic acid were also recorded. The DNA and RNA extracted from bacteria were then respectively subjected to polymerase chain reaction(PCR) and reverse transcription PCR(RT-PCR) to further confirm its quality. The results indicated that our method can be successfully used to simultaneously extract DNA and RNA from bacteria. | Jiuhai Wang Zeeshan Ali Nianyue Wang Wenbiao Liang Hongna Liu Fu Li Haowen Yang Lei He Libo Nie Nongyue He Zhiyang Li | 2015 | Science China Chemistry2015，58，11： | 5 |
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