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1Dysfunction of peripheral blood dendritic cells from patients with chronic hepatitis B virus infection显示文摘AIM To identify the property of dendritic cella (DCs) of peripheral blood monocytes (PBMC) in patlents with chronic HBV infection.METHODS Twenty patients with persistent HBV infectlon were included in this study, 10 healthy subjects being used as a control group. The peripheral blood mononuclear cells (PBMC) of T cell-depleted populations were incubated and induced into mature dendritic cells in the RPMI-1640 medium in the presence of cytokines GMCSF, IL-4, FLt-3, TNF-α and 100 mL@ L-1 of fetal calf serum for a total of 10 - 12 days. The expressions of surface markers on DCs were evaluated using flow cytometric analysis. ELISA method was used to determine the cytokine levels of interleukin-12 (IL-12) and IL-10 in the supernatant produced by DCs. For detection of the stimulatory capacity of DCs to T cell proliferation,mytomycin C-treated DC were incubated with allogenic T cells.RESULTS A typical morphology of mature DCs from healthy subjects and HBV-infected patients was induced in in vitro incubation, but the proliferation ability and cellular number of DCs from HBV-infected patients significantly decreased compared with healthy individuals. In particular, the expression levels of HLADR, CD80 (B7-1) and CD86 (B7-2) on DC surface from patients were also lower than that from healthy individuals (0.46 vs 0.92 for HLA-DR, 0.44 vs 0.88 for CD80 and 0.44 vs 0. 84 for CD86, P< 0.05). The stimulatory capacity and production of IL-12 of DCs from patients in allogenic mixed lymphocyte reaction (AMLR) significantly decreased, but the production level of nitric oxide (NO) by DCa simultaneously increased compared with healthy subjects (86± 15 vs 170±22 μmoI@L 1, P<0.05).CONCLUSION The patients with chronic HBV infection have the defective function and immature phenotype of dendritic cells, which may be associated with the inability of efficient presentation of HBV antigens to host immune system for the clearance of HBV.Fu-Sheng Wang Li-He Xing Ming-Xu Liu Chuan-Lin Zhu Hui-Gang Liu Hui-Fen Wang Zhou-Yun Lei Division of Biological Engineering,~2 Fourth Department of Liver Diseases,Beijing Institute of Infectious Diseases,Beijing Hospital of Infectious Diseases,Beijing 100039,China 2001World Journal of Gastroenterology2001,7,4:131
2Production of bioactive ginsenoside compound K in metabolically engineered yeast显示文摘Xing Yan Yun Fan Wei Wei Pingping Wang Qunfang Liu Yongjun Wei Lei Zhang Guoping Zhao Jianmin Yue Zhihua Zhou 2014Cell Research2014,24,6:81
32018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up.Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu 2018Science Bulletin2018,63,23:54
4Recent Advances in Synthesis of Waterborne Polyurethane and Their Application in Water-based Ink:A Review显示文摘Over the last few years,waterborne polyurethane(WPU) was applied to various fibers,adhesives,primers for metals,caulking materials,emulsion polymerization media,paint additives,defoamers,associate thickeners,pigment pastes,textile dyes and biomaterials,resulting in the increasing enthusiasm of researchers to design and synthesize novel WPU with unique properties.Thus,various processes and raw materials have been developed to prepare WPU.This review gives an overview on the developments of WPU mainly derived from novel polyols,analyzes the potential application in water-based inks and presents the probable future research area about water-based inks.Notably,the poly(ε-caprolactone) and poly(lactic acid) are the versatile materials used in WPU synthesis and supply the potential special performance for preparing WPU.Meanwhile,addition-fragmentation chain transfer(RAFT) polymerization and atom transfer radical polymerization(ATRP) processes provide an opportunity to control the chain sequence of WPU and obtain products with the desired performance.Xing Zhou Yan Li Changqing Fang Shujuan Li Youliang Cheng Wanqing Lei Xiangjie Meng 2015Journal of Materials Science & Technology2015,31,7:47
5Study of time-domain digital pulse shaping algorithms for nuclear signals显示文摘With the development on high-speed integrated circuit,fast high resolution sampling ADC and digital signal processors are replacing analog shaping amplifier circuit.This paper firstly presents the numerical analysis and simulation on R-C shaping circuit model and C-R shaping circuit model.Mathematic models are established based on 1st order digital differential method and Kirchhoff Current Law in time domain,and a simulation and error evaluation experiment on an ideal digital signal are carried out with Excel VBA.A digital shaping test for a semiconductor X-ray detector in real time is also presented.Then a numerical analysis for Sallen-Key(S-K) low-pass filter circuit model is implemented based on the analysis of digital R-C and digital C-R shaping methods.By applying the 2nd order non-homogeneous differential equation,the authors implement a digital Gaussian filter model for a standard exponential-decaying signal and a nuclear pulse signal.Finally,computer simulations and experimental tests are carried out and the results show the possibility of the digital pulse processing algorithms.ZHOU Jianbin ZHOU Wei LEI Jiarong TUO Xianguo ZHU Xing LIU Yi 2012Nuclear Science and Techniques2012,23,3:34
6Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang 2014Cell Research2014,24,10:33
7High-entropy ceramics:Present status,challenges,and a look forward显示文摘High-entropy ceramics (HECs) are solid solutions of inorganic compounds with one or more Wyckoff sites shared by equal or near-equal atomic ratios of multi-principal elements.Although in the infant stage,the emerging of this new family of materials has brought new opportunities for material design and property tailoring.Distinct from metals,the diversity in crystal structure and electronic structure of ceramics provides huge space for properties tuning through band structure engineering and phonon engineering.Aside from strengthening,hardening,and low thermal conductivity that have already been found in high-entropy alloys,new properties like colossal dielectric constant,super ionic conductivity,severe anisotropic thermal expansion coefficient,strong electromagnetic wave absorption,etc.,have been discovered in HECs.As a response to the rapid development in this nascent field,this article gives a comprehensive review on the structure features,theoretical methods for stability and property prediction,processing routes,novel properties,and prospective applications of HECs.The challenges on processing,characterization,and property predictions are also emphasized.Finally,future directions for new material exploration,novel processing,fundamental understanding,in-depth characterization,and database assessments are given.Huimin XIANG Yan XING Fu-zhi DAI Hongjie WANG Lei SU Lei MIAO Guojun ZHANG Yiguang WANG Xiwei QI Lei YAO Hailong WANG Biao ZHAO Jianqiang LI Yanchun ZHOU 2021Journal of Advanced Ceramics2021,10,3:28
8A Genome-Wide Transcription Analysis Reveals a Close Correlation of Promoter INDEL Polymorphism and Heterotic Gene Expression in Rice Hybrids显示文摘杂种优势,或混合活力,指二个生来的变化的混合子孙在展出提高的生长或农学的性能的现象。尽管研究的世纪长的历史关于杂种优势的基因基础产生了几个假设,位于杂种优势和 heterotic 基因表示下面的分子的机制留下逃犯。这里,我们在米饭报导二个 heterotic 十字的染色体宽的基因表示分析,利用它的充分定序的染色体。约 79% 基因是从 heterotic 十字的二个集合在幼苗射击表示的差别,包括许多抄写因素基因,并且展出了基因行动的多重模式。在生来的父母之间的 ortholog 基因的通常认为的倡导者区域的比较揭示了广泛的顺序变化,特别地小的插入 / 删除(INDEL ) ,许多哪个在通常认为的 cis 规章的元素的形成 / 混乱的结果。一起,这些结果建议那在抄写因素和多态的倡导者的表示之间的组合相互影响在混血儿的 cis 规章的元素是位于 heterotic 基因行动下面的一嘴巧的分子的机制并且这样在米饭的杂种优势。Hui-Yong Zhang Hang He Liang-Bi Chen Lei Li Man-Zhong Liang Xiang-Feng Wang Xi-Gang Liu Guang-Ming He Run-Sheng Chen Li-Geng Ma Xing Wang Deng 2008Molecular Plant2008,1,5:25
9Progress of Air Pollution Control in China and Its Challenges and Opportunities in the Ecological Civilization Era显示文摘China’s past economic growth has substantially relied on fossil fuels,causing serious air pollution issues.Decoupling economic growth and pollution has become the focus in developing ecological civilization in China.We have analyzed the three-decade progress of air pollution controls in China,highlighting a strategic transformation from emission control toward air quality management.Emission control of sulfur dioxide(SO2)resolved the deteriorating acid rain issue in China in 2007.Since 2013,control actions on multiple precursors and sectors have targeted the reduction of the concentration of fine particulate matter(PM2.5),marking a transition to an air-quality-oriented strategy.Increasing ozone(O3)pollution further requires O3 and PM2.5 integrated control strategies with an emphasis on their complex photochemical interactions.Fundamental improvement of air quality in China,as a key indicator for the success of ecological civilization construction,demands the deep de-carbonization of China’s energy system as well as more synergistic pathways to address air pollution and global climate change simultaneously.Xi Lu Shaojun Zhang Jia Xing Yunjie Wang Wenhui Chen Dian Ding Ye Wu Shuxiao Wang Lei Duan Jiming Hao 2020Engineering2020,6,12:24
10Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China.Kaiwen Li Tianxin Lin Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang 2015Asian Journal of Urology2015,2,2:21
11The Role of Fibrocyte in the Pathogenesis of Silicosis显示文摘Exposure to free silica induces silicosis and myofibroblasts are regarded as primary effector cells.Fibrocytes can differentiate into myofibroblast.Therefore,the present study was designed to investigate whetherLI Juan YAO Wu HOU Jian Yong ZHANG Lin BAO Lei CHEN Hui Ting WANG Di YUE Zhong Zheng LI Yi Ping ZHANG Miao YU Xing Hao ZHANG Jian Hui QU Ya Qian HAO Chang Fu 2018Biomedical and Environmental Sciences2018,31,4:20
12Clinical study of midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in intensive care unit显示文摘Xing Lu Jun Li Tong Li Jie Zhang Zhi-Bo Li Xin-Jing Gao Lei Xu 2016Chinese Journal of Traumatology2016,19,2:20
13Biphasic insulin aspart 30 improved glycemic control in Chinese patients with type 2 diabetes poorly controlled on oral glucose-lowering drugs: a subgroup analysis of the A1chieve study显示文摘Chen Liming Xing Xiaoyan Lei Minxiang Liu Jie Shi Yongquan Li Pengqiu Qin Guijun Li Chengjiang Li Yukun Wang Qing Gao Tianshu Hu Ling Wang Yangwei Yang Wenying 2014Chinese Medical Journal2014,,2:19
14Effects of slow or controlled release fertilizer types and fertilization modes on yield and quality of rice显示文摘There is limited information about the influence of slow or controlled release fertilizer(S/CRF) on rice yield and quality. In this study, japonica rice cultivar Nanjing 9108 was used to study the effects of three different S/CRFs(polymer-coated urea(PCU), sulfur-coated urea(SCU), and urea formaldehyde(UF)) and two fertilization modes(both S/CRF and common urea(CU) as basal fertilizer, S/CRF as basal and CU as tillering fertilizer) on rice yield and quality. CU only was applied separately as control(CK). Results showed that, rice grain yield, chalky kernel rate, chalky area, overall chalkiness, and the content of gliadin, glutenin, and protein, all showed the trends of UF>PCU>SCU within the same fertilization mode, and showed the trends of S/CRF as basal and CU as tillering fertilizer>both S/CRF and CU as basal fertilizer within the same type of S/CRF. In contrast, the contents of amylose, amylopectin, and starch, as well as taste value, and peak and hot viscosity showed trends of SCU>PCU>UF, and the trends of both S/CRF and CU as basal fertilizer>S/CRF as basal and CU as tillering fertilizer. Among S/CRF treatments and fertilization modes, taste values of cooked rice were positively correlated with amylose, amylopectin, and starch contents, as well as gel consistency, peak viscosity, hot viscosity, and cool viscosity, while negatively correlated with globulin, gliadin, glutenin, and protein contents. The types of S/CRF and fertilization modes are important for improving rice yield and quality. Compared to CK, higher yield and similar quality of rice was achieved with UF as basal and CU as tillering fertilizer, and similar yield with improved appearance and eating and cooking quality of rice was achieved with either both UF and CU as basal fertilizer, or PCU as basal and CU as tillering fertilizer.WEI Hai-yan CHEN Zhi-feng XING Zhi-peng ZHOU Lei LIU Qiu-yuan ZHANG Zhen-zhen JIANG Yan HU Ya-jie ZHU Jin-yan CUI Pei-yuan DAI Qi-gen ZHANG Hong-cheng 2018Journal of Integrative Agriculture2018,17,10:19
15Comparisons between centrifuge and numerical modeling results for slope toppling failure显示文摘This paper presents series studies on the toppling mechanism by centrifuge tests and numerical simulations. Two different discrete element methods, i.e., the continuum-based discrete element method(CDEM) and the discontinuous deformation analysis(DDA), are adopted. The modeling results show that both the methods can accurately capture the failure modes of the centrifuge tests, including three distinct zones and two failure surfaces. Comparisons are made between the physical test and numerical simulation results. The critical inclination angle of the tilting table where the slope models are fixed on can be moderately predicted by the two methods, with different degrees of precision. The error between the test results and the simulated results is within 1% for the slope models without rock-bridges by both CDEM and DDA. However, it is amplified for the staggered-joint models that simulate the rock-bridges. With DDA, the average error is about 5%, and the maximum error is up to 17%. While with CDEM, the errors for the aligned-joint models are ranged from 1% to 6%, and it is from 10% to 29% for the staggered-joint models. The two numerical methods show the capability in simulating toppling failure of blocky rock mass with and without rock-bridges. The model with rock-bridges which provides a certain bending resistance is more stable than the one without any rock-bridge. In addition, the two failure surfaces were observed, which is different from the common understanding that only one failure surface appears.CHEN ZuYu GONG WenJun MA GuoWei WANG Jie HE Lei XING YiChuan XING JianYing 2015Science China(Technological Sciences)2015,58,9:18
16Biomarker reconstruction of phytoplankton productiv-ity and community structure changes in the middle Okinawa Trough during the last 15 ka显示文摘Biomarkers have been widely used to reconstruct phytoplankton productivity and community structure changes, and this method has been applied for the first time in the middle Okinawa Trough during the transition from the last deglaciation to the Holocene. The total content of all marine phytoplankton biomarkers, used as a total productivity indicator, reveals higher productivity during the deglaciation. The ratios of the biomarkers are used as community structure indicators which show that, compared with the Holocene, the contribution from haptophytes decreased while the contributions from diatoms and dinoflagellates increased during the deglaciation. The increased productivity during the deglacia- tion was likely caused by the stronger winter monsoon. Also increased nutrient supply from terrestrial sources contributes to the higher productivity due to lower sea-level, which is consistent with higher terrestrial biomarker (long-chain n-alkanols) content. These changes in the nutrient supply also con- tributed to the community structure changes in the Okinawa Trough.XING Lei ZHAO MeiXun ZHANG HaiLong LIU YanGuang SHI XueFa 2008Chinese Science Bulletin2008,53,16:17
17Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment显示文摘Shuping Zhang 2015Cellular & Molecular Immunology2015,12,5:17
18Human umbilical cord-derived mesenchymal stem cell therapy in patients with COVID-19:a phase 1 clinical trial显示文摘No effective drug treatments are available for coronavirus disease 2019(COVID-19).Host-directed therapies targeting the underlying aberrant immune responses leading to pulmonary tissue damage,death,or long-term functional disability in survivors require clinical evaluation.We performed a parallel assigned controlled,non-randomized,phase 1 clinical trial to evaluate the safety of human umbilical cord-derived mesenchymal stem cells(UC-MSCs)infusions in the treatment of patients with moderate and severe COVID-19 pulmonary disease.The study enrolled 18 hospitalized patients with COVID-19(n=9 for each group).The treatment group received three cycles of intravenous infusion of UC-MSCs(3×107 cells per infusion)on days 0,3,and 6.Both groups received standard COVID-treatment regimens.Adverse events,duration of clinical symptoms,laboratory parameters,length of hospitalization,serial chest computed tomography(CT)images,the PaO2/FiO2 ratio,dynamics of cytokines,and IgG and IgM anti-SARS-CoV-2 antibodies were analyzed.No serious UC-MSCs infusion-associated adverse events were observed.Two patients receiving UC-MSCs developed transient facial flushing and fever,and one patient developed transient hypoxia at 12 h post UC-MSCs transfusion.Mechanical ventilation was required in one patient in the treatment group compared with four in the control group.All patients recovered and were discharged.Our data show that intravenous UC-MSCs infusion in patients with moderate and severe COVID-19 is safe and well tolerated.Phase 2/3 randomized,controlled,double-blinded trials with long-term follow-up are needed to evaluate the therapeutic use of UC-MSCs to reduce deaths and improve long-term treatment outcomes in patients with serious COVID-19.Fanping Meng Ruonan Xu Siyu Wang Zhe Xu Chao Zhang Yuanyuan Li Tao Yang Lei Shi Junliang Fu Tianjun Jiang Lei Huang Peng Zhao Xin Yuan Xing Fan Ji-Yuan Zhang Jinwen Song Dawei Zhang Yanmei Jiao Limin Liu Chunbao Zhou Markus Maeurer Alimuddin Zumla Ming Shi Fu-Sheng Wang 2020Signal Transduction and Targeted Therapy2020,5,1:16
19Generating dense and super-resolution ISAR image by combining bandwidth extrapolation and compressive sensing显示文摘Recent developing compressive sensing (CS) theory indicates that it is possible to obtain precise recovery of a sparse signal from very limited measurements,which provides a new way for data acquisition and signal processing as nature signals usually involve some degree of sparsity.In this paper,we present an algorithm for inversed synthetic aperture radar (ISAR) imaging with super resolution by combining CS and bandwidth extrapolation (BWE) technique.For ISAR imaging,the backscattering field of target is usually contributed by a few strong scattering centers,whose number is much less than that of image pixels.Thus,CS is intuitively suitable for constructing super resolution ISAR image.According to CS theory,the number of extracted dominating scatterers relies on the signal length,which indicates that if only limited data is available,it is difficult to generate dense ISAR image robustly by CS,and some signal components tend to lose.To soften this constraint,BWE is combined with CS imaging to increase the degree of freedom of signal while preserving its coherence.A refined CS-based formation for ISAR image-resolution enhancement is then developed.Both real and simulated data experiments are performed to evaluate the proposed approach,and an example of using this technique demonstrates the enhanced image resolution in application of maneuvering target imaging.QUAN YingHui ZHANG Lei GUO Rui XING MengDao BAO Zheng 2011Science China(Information Sciences)2011,54,10:15
20Role of baicalin in regulating Toll-like receptor 2/4 after ischemic neuronal injury显示文摘LI Hui-ying YUAN Zhi-yi WANG Yu-gang WAN Hong-jiao HU Jun CHAI Yu-shuang LEI Fan XING Dong-ming DU Li-jun 2012Chinese Medical Journal2012,,9:15
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