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| 1 | Regional assessment of cadmium pollution in agricultural lands and the potential health risk related to intensive mining activities: A case study in Chenzhou City, China显示文摘The purpose of this study was to assess the extent of cadmium (Cd) contamination in agricultural soil and its potential risk for people. Soils, rice, and vegetables from Chenzhou City, Southern China were sampled and analyzed. In the surface soils, the 95% confidence interval for the mean concentration of Cd varied between 2.72 and 4.83 mg/kg (P < 0.05) in the survey, with a geometric mean concentration of 1.45 mg/kg. Based on the GIS map, two hot spot areas of Cd in agricultural soils with high Cd concentrations were identified to be located around the Shizhuyuan, Jinshiling, and Yaogangxian mines, and the Baoshan and Huangshaping mines, in the center of the city. About 60% of the total investigated area, where the agricultural soil Cd concentration is above 1 mg/kg, is distributed in a central belt across the region. The critical distances, at which the soil Cd concentration were increased by the mining activities, from the mines of the soils were 23 km for the Baoshan mine, 46 km for the Huangshaping mine, and 63 km for the Shizhuyuan mine, respectively. These are distances calculated from models. The Cd concentrations in rice samples ranged from 0.01 to 4.43 mg/kg and the mean dietary Cd intake from rice for an adult was 191 μg/d. Results of risk indexes showed that soil Cd concentrations possessed risks to local residents whose intake of Cd from rice and vegetables grown in soils in the vicinity of the mine was 596 μg/d. | ZHAI Limei LIAO Xiaoyong CHEN Tongbin YAN Xiulan XIE Hua WU Bin WANG Lixia | 2008 | Journal of Environmental Sciences2008，20，6： | 35 |
| 2 | Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth显示文摘 | Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang | 2014 | Cell Research2014，24，10： | 33 |
| 3 | A prospective comparative study on neovascular glaucoma and non- neovascular refractory glaucoma following Ahmed glaucoma valve implantation显示文摘 | Li Zheng Zhou Minwen Wang Wei Huang Wenbin Chen Shida Li Xingyi Gao Xinbo Zhang Xiulan | 2014 | Chinese Medical Journal2014，，8： | 18 |
| 4 | Subcellular distribution and compartmentalization of arsenic in Pteris vittata L.显示文摘The subcellular distribution of arsenic (As) in Pteris vittata L., an As-hyperaccumulator, was studied to de- termine As compartmentalization and to explore the mecha- nisms that confer As tolerance. When the plant was grown in a nutrient solution without additional As, most of the accu- mulated As was isolated to the cell wall. However, in plants growing in a nutrient solution containing 0.1 or 0.2 mmol/L As, approximately 78% of the total As accumulated within the pinna. The proportions of As accumulation in the cyto- plasmic supernatant fraction were 78% of that in the pinna and 61% of that in the plant. In either treatment group (0.1 or 0.2 mmol/L As), the fraction containing the lowest level of As was the organelle fraction. These results suggest that As accumulates in the pinna where it is primarily distributed in the cytoplasmic supernatant fraction. The role of As com- partmentalization may be intricately linked with As detoxi- fication in P. vittata L. | CHEN Tongbin YAN Xiulan LIAO Xiaoyong XIAO Xiyuan HUANG Zechun XIE Hua ZHAI Limei | 2005 | Chinese Science Bulletin2005，50，24： | 17 |
| 5 | Oleic Acid and Eicosapentaenoic Acid Reverse Palmitic Acid-induced Insulin Resistance in Human HepG2 Cells via the Reactive Oxygen Species/JUN Pathway显示文摘Oleic acid(OA),a monounsaturated fatty acid(MUFA),has previously been shown to reverse saturated fatty acid palmitic acid(PA)-induced hepatic insulin resistance(IR).However,its underlying molecular mechanism is unclear.In addition,previous studies have shown that eicosapentaenoic acid(EPA),aω-3 polyunsaturated fatty acid(PUFA),reverses PA-induced muscle IR,but whether EPA plays the same role in hepatic IR and its possible mechanism involved need to be further clarified.Here,we confirmed that EPA reversed PA-induced IR in HepG2 cells and compared the proteomic changes in HepG2 cells after treatment with different free fatty acids(FFAs).A total of 234 proteins were determined to be differentially expressed after PA+OA treatment.Their functions were mainly related to responses to stress and endogenous stimuli,lipid metabolic process,and protein binding.For PA+EPA treatment,the PA-induced expression changes of 1326 proteins could be reversed by EPA,415 of which were mitochondrial proteins,with most of the functional proteins involved in oxidative phosphorylation(OXPHOS)and tricarboxylic acid(TCA)cycle.Mechanistic studies revealed that the protein encoded by JUN and reactive oxygen species(ROS)play a role in OA-and EPA-reversed PA-induced IR,respectively.EPA and OA alleviated PA-induced abnormal adenosine triphosphate(ATP)production,ROS generation,and calcium(Ca^(2+))content.Importantly,H_(2)O_(2)-activated production of ROS increased the protein expression of JUN,further resulting in IR in HepG2 cells.Taken together,we demonstrate that ROS/JUN is a common response pathway employed by HepG2 cells toward FFA-regulated IR. | Yaping Sun Jifeng Wang Xiaojing Guo Nali Zhu Lili Niu Xiang Ding Zhensheng Xie Xiulan Chen Fuquan Yang | 2021 | Genomics, Proteomics & Bioinformatics2021，19，5： | 6 |
| 6 | Quantitative Proteomics Using Isobaric Labeling:A Practical Guide显示文摘In the past decade,relative proteomic quantification using isobaric labeling technology has developed into a key tool for comparing the expression of proteins in biological samples.Although its multiplexing capacity and flexibility make this a valuable technology for addressing various biological questions,its quantitative accuracy and precision still pose significant challenges to the reliability of its quantification results.Here,we give a detailed overview of the different kinds of isobaric mass tags and the advantages and disadvantages of the isobaric labeling method.We also discuss which precautions should be taken at each step of the isobaric labeling workflow,to obtain reliable quantification results in large-scale quantitative proteomics experiments.In the last section,we discuss the broad applications of the isobaric labeling technology in biological and clinical studies,with an emphasis on thermal proteome profiling and proteogenomics. | Xiulan Chen Yaping Sun Tingting Zhang Lian Shu Peter Roepstorff Fuquan Yang | 2021 | Genomics, Proteomics & Bioinformatics2021，19，5： | 5 |
| 7 | Online Identification of Power Battery Parameters for Electric Vehicles Using a Decoupling Multiple Forgetting Factors Recursive Least Squares Method显示文摘Li-ion batteries are widely used in electric vehicles(EVs).However,the accuracy of online SOC estimation is still challenging due to the time-varying parameters in batteries.This paper proposes a decoupling multiple forgetting factors recursive least squares method(DMFFRLS)for EV battery parameter identification.The errors caused by the different parameters are separated and each parameter is tracked independently taking into account the different physical characteristics of the battery parameters.The Thevenin equivalent circuit model(ECM)is employed considering the complexity of battery management system(BMS)on the basis of comparative analysis of several common battery ECMs.In addition,decoupling multiple forgetting factors are used to update the covariance due to different degrees of error of each parameter in the identification process.Numerous experiments are employed to verify the proposed DMFFRLS method.The parameters for commonly used LiFePO4(LFP),Li(NiCoMn)O2(NCM)battery cells and battery packs are identified based on the proposed DMFFRLS method and three conventional methods.The experimental results show that the error of the DMFFRLS method is less than 15 mV,which is significantly lower than the conventional methods.The proposed DMFFRLS shows good performance for parameter identification on different kind of batteries,and provides a basis for state of charge(SOC)estimation and BMS design of EVs. | Xiulan Liu Yuan Jin Shuang Zeng Xi Chen Yi Feng Shiqi Liu Haolu Liu | 2020 | CSEE Journal of Power and Energy Systems2020，6，3： | 5 |
| 8 | Expression analysis of two novel cotton 14-3-3 genes in root development and in response to salt stress显示文摘14-3-3 proteins are phosphoserine-binding proteins that regulate the activities of a wide array of targets via direct protein-protein interactions,and may play an important role in response to biotic and abiotic stresses. In this study,two cDNAs (designated as Gh14-3-3b and Gh14-3-3c) encoding putative 14-3-3 proteins were isolated from cotton cDNA libraries. Gh14-3-3b gene encodes a pro-tein of 268 amino acids,while Gh14-3-3c gene encodes a protein of 261 amino acids. Real-time RT-PCR analysis revealed that both the Gh14-3-3b and Gh14-3-3c genes were preferentially expressed in roots. The transcript levels of both the genes were the highest in 3-day-old roots,and then dramatically decreased to relatively low levels in parallel with root development. In addition,the expression of these Gh14-3-3 genes in roots was significantly up regulated by salt treatments,suggesting that they may be involved in the signaling pathways in response to salt stress in cotton. | Xinzheng Wei Zeting Zhang Yang Li Xiulan Wang Suqiang Shao Liang Chen Xuebao Li | 2009 | Progress in Natural Science:Materials International2009，19，2： | 5 |
| 9 | Collection efficiency in a three-dimensional randomly arranged dual-layer granular bed filter显示文摘The dual-layer granular bed filter packed with randomly arranged granules was simulated to study the effects of bed depth of the lower layer of fine granules and the inlet gas velocity on the collection mechanism.The computational results show that the collection efficiency is much better from this granular bed than a single-layer granular bed,especially for particle diameters of 1-10μm.The inlet gas velocity has less effect on the grade collection efficiency of the dual-layer granular bed than of the single-layer granular bed.The dual-layer granular bed provides a high collection efficiency and low pressure drop.The relationship between the grade collection efficiency and the Stokes number(St)based on the inlet gas velocity is obtained.If St is below a threshold,the grade collection efficiency remains stable;if St is in value above threshold,the grade collection efficiency increases linearly with lg(St).As the bed depth of the lower layer of fine granules increases,the threshold for St shifts forward. | Junlin Chen Xunfeng Li Xiulan Huai Jingzhi Zhou | 2020 | Particuology2020，18，2： | 3 |
| 10 | Mitochondria in the pathogenesis of diabetes:a proteomic view显示文摘Diabetes mellitus is a complex metabolic disorder characterized by chronic hyperglycemia due to absolute or relative lack of insulin.Though great efforts have been made to investigate the pathogenesis of diabetes,the underlying mechanism behind the development of diabetes and its complications remains unexplored.Cumulative evidence has linked mitochondrial modification to the pathogenesis of diabetes and its complications and they are also observed in various tissues affected by diabetes.Proteomics is an attractive tool for the study of diabetes since it allows researchers to compare normal and diabetic samples by identifying and quantifying the differentially expressed proteins in tissues,cells or organelles.Great progress has already been made in mitochondrial proteomics to elucidate the role of mitochondria in the pathogenesis of diabetes and its complications.Further studies on the changes of mitochondrial protein specifically post-translational modifications during the diabetic state using proteomic tools,would provide more information to better understand diabetes. | Xiulan Chen Shasha Wei Fuquan Yang | 2012 | Protein & Cell2012，3，9： | 3 |
| 11 | Family-level diversity of extracellular proteases of sedimentary bacteria from the South China Sea显示文摘Protease-producing bacteria and their extracellular proteases are key players in degrading organic nitrogen to drive marine nitrogen cycling and yet knowledge on both of them is still very limited. This study screened protease-producing bacteria from the South China Sea sediments and analyzed the diversity of their extracellular proteases at the family level through N-terminal amino acid sequencing. Results of the 16 S rRNA gene sequence analysis showed that all screened protease-producing bacteria belonged to the class Gammaproteobacteria and most of them were affiliated with different genera within the orders Alteromonadales and Vibrionales. The Nterminal amino acid sequence analysis for fourteen extracellular proteases from fourteen screened bacterial strains revealed that all these proteases belonged to the M4 family of metalloproteases or the S8 family of serine proteases. This study presents new details on taxa of marine sedimentary protease-producing bacteria and types of their extracellular proteases, which will help to comprehensively understand the process and mechanism of the microbial enzymatic degradation of marine sedimentary organic nitrogen. | Jinyu Yang Yangyang Feng Xiulan Chen Binbin Xie Yuzhong Zhang Mei Shi Xiying Zhang | 2019 | Acta Oceanologica Sinica2019，38，12： | 3 |
| 12 | Synthesis of iron-based nanoparticles by green tea extract and their degradation of malachite显示文摘 | Xiulan Weng Lanlan Huang Zuliang Chen Mallavarapu Megharaj Ravendra Naidu | 2013 | Industrial Crops & Products2013，，： | 2 |
| 13 | Numerical study of collection efficiency and heat-transfer characteristics of packed granular filter显示文摘The collection mechanism and heat-transfer characteristics of a packed granular filter were investigated using a three-dimensional randomly packed granular filter model. The bridging method was introduced to optimize the grids of contact points between granules. The influences of granular bed depth, gas velocity, and gas temperature on grade collection efficiency were investigated. The results indicated that a decrease of temperature improved collection efficiency when the particle diameter was greater than 5 |xm. The grade collection efficiency maintained a stable value when the Stokes number, St, was less than 0.009, but increased linearly with ig(St) when St > 0.009. A logarithmic mean temperature difference method was used to obtain overall heat-transfer coefficients of gas-solid two-phase flow through the packed granular filter. The results showed that convective heat transfer was enhanced due to the intro-duction of solid particles in the bed. The overall heat-transfer coefficient increased approximately linearly with an increase in particle loading ratio. The Nusselt number was related to the Reynolds number, the Archimedes number, and the particle loading ratio. | Junlin Chen Xunfeng Li Xiulan Huai Yongwei Wang Jingzhi Zhou | 2019 | Particuology2019，17，5： | 2 |
| 14 | n-Octadecanethiol Self-Assembled Monolayer Coating with Microscopic Roughness for Dropwise Condensation of Steam显示文摘Here we presented a novel technology to achieve a Super-hydrophobic coating with microscopic roughness oncopper surface. First, make a layer of verdigris grow on the fresh pure copper surface. Gain it by exposing thecopper to air and the mist of acetic acid solution. The green coating is a mixture of basic copper(Ⅱ) carbonate andcopper(Ⅱ) acetate. Second heat the coating and make it decompose to CuO. Lastly, form an n-octadecanethiolself-assembled monolayers coating on the outermost surface. Contact angle test, scanning electron microscopeanalysis and electrochemical testing were carried out to characterize the surface, and a heat transfer experimentfor dropwise condensation of steam was performed also. Results show that the modified surface bears a few Super-hydrophobicfeatures, the static contact angle is higher than that in literatures, reaching 153.1±1.7°. The microscopicroughness can be seen in SEM images, differing much from H2O2 etched surface and bare copper surface.The condensation of steam on the surface is a typical form of dropwise condensation, in the measured rangeof temperature difference, under 0.1 MPa, the average convection heat transfer coefficients of the vertical surfaceare 1.7~2.1 times for those of film condensation. At the same time, the inhibition efficiency of surface is improvedto some extent comparing with the same kind of SAMs, which suggests that the lifetime of maintenancedropwise condensation would have the possibility to surpass the existing record. | Liang CHEN Shiqiang LIANG Runsheng YAN Yanjun CHENG Xiulan HUA Shuling CHEN | 2009 | Journal of Thermal Science2009，18，2： | 2 |
| 15 | Generation of transgenic wheat resistant to wheat yellow mosaic virus and identification of gene silence induced by virus infection显示文摘The plasmid containing the promoter Actl, the coat protein (cp) gene of wheat yellow mosaic virus (WYMV) and the selectable bar gene, was delivered via particle bombardment, directly into immature embryos of a wheat culti-vars. PCR and PCR-RFLP were employed to screen the existence of the cp gene in T0 and T1 generations. Seeds from the positive T1 plants were sowed in fields heavily contaminated with WYMV to detect their resistance. In field trial of virus infection, one of the transgenic wheat lines, P8-T2, exhibited highly disease-resistance. Western blot and RT-PCR analysis showed that the expression level of cp gene in the resistant transgenic line was reduced greatly compared to those susceptible to WYMV infection. This provided evidence to presume that the resistance obtained by the transgenic wheat line was stimulated by the mechanism of the virus induced gene silencing. | DONG Jin HE Zhentian HAN Chenggui CHEN Xiulan ZHANG Lingdi LIU Weihua HAN Yuepeng WANG Jinrong ZHAI Yafeng YU Jialin LIU Yi XIAO Yueyan | 2002 | Chinese Science Bulletin2002，47，17： | 2 |
| 16 | Electrical properties of yttrium calcium oxyborate crystal annealed at high temperature and low oxygen partial pressure显示文摘The yttrium calcium oxyborate crystal(YCa_(4)O(BO_(3))_(3),YCOB)has been actively studied for hightemperature piezoelectric sensing applications.In this work,the stability of electric properties of YCOB crystal annealed in critical conditions(high-temperatures of 900-1100℃ with a low oxygen partial pressure of 4×10^(-6) atm for 24 h)was investigated and the recovery mechanism for the electrical resisitivity,dielectric permittivity and dielectric loss were studied,taking advantage of the X-ray photoelectron spectra and the first principle calculations.The electrical resistivity of the annealed YCOB crystal was slightly decreased when compared to the pristine counterpart,being(2-5)×10^(7) Ω·cm at 850C.The dielectric permittivity and dielectric loss were found to increase after annealing,showing recoverable behaviours after thermal treatment above 650℃ in air.The calculated vacancy formation energy indicates that the oxygen vacancy is the dominant defects in YCOB.The formation of oxygen vacancy weakens the chemical bonding strength between B(Ca or Y)and O atoms,introduces extra donor levels in the band gap,which excites the electrons to conduction band more easily thus enhances the electrical conductivity and dielectric loss.The recovered electrical properties are believed to be associated with the reduced vacancy defects at elevated temperatures in air. | Shiwei Tian Lili Li Feifei Chen Chao Jiang Fapeng Yu Yanlu Li Xiulan Duan Zhengping Wang Shujun Zhang Xian Zhao | 2019 | Journal of Materiomics2019，5，3： | 2 |
| 17 | Carrier concentration profiling in magnetic GaMnSb/GaSb investigated by electrochemistry capacitance-voltage profiler显示文摘Depth profiles of carrier concentrations in Ga-MnSb/GaSb are investigated by electrochemistry capacitance-voltage profiler and electrolyte of Tiron. The carrier concentration in GaMnSb/GaSb measured by this method is coincident with the results of Hall and X-ray diffraction measurements. It is indicated that most of the Mn atoms in GaMnSb take the site of Ga, play a role of acceptors, and provide shallow acceptor level(s). | ZHANG Xiulan ZHANG Fuqiang SONG Shulin CHEN Nuofu WANG Zhanguo LIN Lanying | 2002 | Chinese Science Bulletin2002，47，21： | 1 |
| 18 | The Role of Antioxidation in Beneficial Effect of Proper Stress on Mice′sBehavior显示文摘The purpose of this study is to elucidate the mechanism of delaying aging process under proper stress. An aging model was established by intraperitoneal injection of D galactose at the dose of 0.12 mg·(g·d) -1 for six weeks, and swimming daily for 15min at 18℃ water was used as proper stressor. Six weeks later, learning and memory ability, the contents of SOD and MDA in hippocampus and heart were measured. The results showed that proper stress could ①retard the decline of learning and memory ability (P<0.001) induced by D galactose;②increase the content of SOD (P<0.001) and reduce the production of MDA (P<0.05). The results indicated that proper stress may delay aging process by improving the antioxidant level and reducing the toxicity of free radicals. | Sun Xiulan(孙秀兰) Gu Luo(顾 洛) Zhang Xiaohu(张小虎) Chen Qisheng(陈启盛)Department of Physiology, Nanjing Medical University,Nanjing 210029, P. R. China | 1999 | The Journal of Biomedical Research1999，23，2： | 1 |
| 19 | Investigation on the applicability of turbulent- Prandtl-number models for liquid lead-bismuth euteetie 显示文摘 | CHEN Fei HUAI Xiulan CAI Juan | 2013 | Nuclear Engineering and Design2013，257，： | 1 |
| 20 | Effects of Chemical Reaction Caused by Cooling Stream on Film Cooling Effectiveness显示文摘With the increase of inlet temperature of gas turbines, the benefits by using the conventional methods are likely to approach their limits. Therefore, it is essential to study novel film cooling methods for surpassing these current limits. Based on the theory of heat transfer enhancement, a film cooling method with chemical reaction by cool- ing stream is proposed. In order to test the feasibility of the proposed method, numerical simulations have been conducted. The classic flat plate structure with a 30 degree hole is used for the simulation. In the present study, the effects of the parameters in relation to the chemical reaction on film cooling effectiveness, such as chemical heat sink, volume changes, and reaction rate, are investigated numerically. The conventional film cooling is also calculated for the comparison. The results show that film cooling effectiveness is improved obviously due to the chemical reaction, and the reaction heat and reaction rate of cooling stream have an important effect on film ef- fectiveness. However, the effect of volume changes can be ignored. | Keyong Cheng Shiqiang Liang Xiulan Huai Wei Chen Yongxian Guo | 2012 | Journal of Thermal Science2012，21，1： | 1 |
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