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| 1 | 颅内出血患者抗栓药逆转指南美国神经重症监护学会和美国重症医学会对医疗卫生专业人员的声明显示文摘背景抗栓药的使用,包括抗凝药、抗血小板药和溶栓药,在过去10年中日益增多并且预计将继续上升。虽然抗栓药相关性颅内出血可能是灾难性的,但快速逆转凝血功能障碍可能有助于限制血肿增大和改善转归。方法美国神经重症监护学会联合美国重症医学会组建了一个国际性多机构委员会,涉及的专业领域包括神经重症监护、神经内科、神经外科、卒中、血液学、血液病理学、急诊医学、药学、护理和指南制定,目的是进行文献评价并制定一份循证实践指南。该委员会进行了正式的文献检索,并对符合标准的研究进行了评价。结果利用GRADE方法学,委员会提出了在颅内出血情况下逆转维生素K拮抗药、直接Xa因子拮抗药、直接凝血酶抑制药、普通肝素、低分子肝素、类肝素、戊多糖、溶栓药和抗血小板药的推荐意见。结论该指南提供了及时和循证的抗栓药逆转策略以协助临床医生治疗抗栓药相关性颅内出血。 | Jennifer A. Frontera John J. Lewin Ⅲ Alejandro A. Rabinstein Imo P. Aisiku Anne W. Alexandrov Aaron M. Cook Gregory J. del Zoppo Monisha A. Kumar Ellinor I. B. Peerschke Michael F. Stiefel Jeanne S Teitelbaum Katja E. Wartenberg Cindy L. Zerfoss 杨一萍 谢丽丽 宁小金 季宇腾 柯开富 | 2016 | 国际脑血管病杂志2016，24，11： | 24 |
| 2 | Applying real time seismic monitoring technology for slope stability assessment—An Indian opencast coal mine perspective显示文摘This paper outlines the results obtained from real time microseismic monitoring of an opencast coal mine in South India.The objective of the study is to investigate the stress changes within the rockmass along the slope due to underground mine development operation and their impact on the stability of the highwall slope.The installed microseismic systems recorded the seismic triggerings down toà2 moment magnitude.In general,most of the events recorded during the monitoring period are weak in seismic energy.The study adopts a simple and more reliable tool to characterize the seismically active zone for assessing the stability of the highwall in real time.The impact of underground working on the slope is studied on the basis of the seismic event impact contours and seismic clusters.During the monitoring period,it is observed that the intensity of the overall microseismic activity along the slope due to the mine development operations did not cause any adverse impact on the highwall stability. | Vinoth S. Ajay Kumar L. | 2014 | International Journal of Mining Science and Technology2014，24，1： | 9 |
| 3 | Effect of micro-environmental factors on natural regeneration of Sal (Shorea robusta)显示文摘Micro-environmental factors viz., soil moisture and light in- tensity are important factors that affect natural regeneration in forests. These factors vary spatially depending on the overhead canopy density of the forest. The present study focused on studying the effect of variation of soil moisture and light intensity on natural regeneration of sal species (Shorea robusta) under different micro-environments due to overhead canopy of varying forest density. Experimental plots of 40m× 40m size were laid under different overhead canopy densities in a small sal for- ested watershed in the foot hills of Himalayas in Nainital District of Uttarakhand State, India. The plots were monitored on a long term basis for soil moisture at multi depths, light intensity and natural regeneration of sal. The results of the study revealed that the natural regeneration was highest under C1 (up to-0.30) canopy followed by C2 (0.30 0.50), and C3 (0.50 0.70) canopies. The C3 canopy showed the dying back of sal shoots over 4 years of study. The highest R 2 value of linear regression between incremental score of plot regeneration and average soil moisture content was obtained as 0.156 for average soil moisture content during non-monsoon months at 100 cm depth. The R 2 value between incre- mental score of plot regeneration and annual average light intensity was obtained as 0.688 which indicated that the regeneration is largely de- pendent on the light intensity conditions during the year. The multiple linear regression analysis between the incremental score of regeneration and the average light intensity and average soil moisture content revealed that that about 80% of variation in regeneration is explained by both the factors. | J. V. Tyagi Rakesh Kumar S. L. Srivastava R. D. Singh | 2011 | Journal of Forestry Research2011，22，4： | 4 |
| 4 | )plication of geo-microbial prospecting method for finding oil and gas reservoirs显示文摘 | M. A. Rasheed Syed Zaheer Hasan P. L. Srinivasa Rao Annapurna Boruah V.Sudarshan B. Kumar T. Harinarayana | 2015 | Frontiers of Earth Science2015，9，1： | 3 |
| 5 | In vivo modulation of androgen receptor by androgens显示文摘Aim:To study the effect of androgen and antiandrogen on the level of androgen receptor(AR)mRNA.Methods:The totalRNA was extracted from the prostate and analyzed by slot blot analysis,The blots were hybrid-ized with ARcDNA probe and 1Aprobe(internal control)and autoradionraphy was performed.The intensity of signal was measured with a densitometer and the ratio of AR RNAand1ARNAwas calculated.Results:Androgenic deprivation produced by castration decreased the weight of the prostate and increased the levels of ARmRNA.Treatment of the castrated rats with testostrone increased the weight of prostate and decreased the levels of ARmRNA.Treatment of normal rats with flutamide decreased the weight of the gland and increased the levels of AR mRNA.Conclusion:Androgens produce proliferative effect on the prostate and negatively regulate the AR transcription. | V. L. Kumar P.K. Majumder V. Kumar | 2002 | Asian Journal of Andrology2002，4，3： | 3 |
| 6 | PLANT RETROTRANSPOSONS显示文摘 | Amar Kumar Jeffrey L. Bennetzen | 1999 | Annual Review of Genetics1999，，： | 3 |
| 7 | The IRAK-ERK-p67phox-Nox-2 axis mediates TLR4, 2-induced ROS production for IL-lp transcription and processing in monocytes显示文摘 | Ankita Singh Vishal Singh Rajiv L. Tiwari Tulika Chandra Ashutosh Kumar Madhu Dikshit Manoj K. Barthwal | 2016 | Cellular & Molecular Immunology2016，13，6： | 3 |
| 8 | Model for end-stage liver disease and Child-Turcotte-Pugh score as predictors of pretransplantation disease severity, posttransplantation outcome, and resource utilization in United Network for Organ Sharing status 2A patients显示文摘 | Robert S. Brown K.Shiva Kumar Mark W. Russo Milan Kinkhabwala Dianne L. Rudow Patricia Harren Steven Lobritto Jean C. Emond | 2002 | Liver Transplantation2002，，3： | 2 |
| 9 | Development and evaluation of a cloud-gap-filled MODIS daily snow-cover product显示文摘 | Dorothy K. Hall George A. Riggs James L. Foster Sujay V. Kumar | 2009 | Remote Sensing of Environment2009，，3： | 2 |
| 10 | 食物特异性IgG4抗体指导的限制性饮食可改善肠易激综合征症状和直肠顺应性 | Zar S. Mincher L. Benson M.J. Kumar D. 郝筱倩 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，12： | 2 |
| 11 | MSH1 Is a Plant Organellar DNA Binding and Thylakoid Protein under Precise Spatial Regulation to Alter Development显示文摘作为新陈代谢的中心,植物细胞器参予维护,防卫,并且发信号。MSH1 是在线粒体和质体涉及 organellar 染色体稳定性的植物特定的蛋白质。MSH1 的质体弄空在开发和 DNA methylation 引起可继承的、非基因的变化。我们从抑制衬里到亚 compartmentalize MSH1 效果的 RNAi 用半互补异种和 transgene 空的 segregants 调查了 msh1 显型。我们证明那 MSH1 表情空间地被调整,明确地在外皮和脉管的实质以内本地化到质体。蛋白质绑 DNA 并且本地化 nucleoids,而是分别和蛋白质蛋白质相互作用数据到质体和 mitochondrial 显示 MSH1 也与 thylakoid 膜联系。在上色,不能生活的压力忍耐,可变生长率,和推迟的成熟的质体 MSH1 弄空结果。从在植物的 7%-10% 的线粒体结果的弄空在叶形态学,热忍耐,和 mitochondrial 染色体稳定性改变了。MSH1 不直接在原子核以内本地化,但是质体弄空在是 MSH1 的可继承的独立人士的 flowering 时间,成熟,和生长率生产非基因的变化。MSH1 弄空在质体和 mitochondrially 改变的线的一个子集改变非光敏的氧化还原作用行为。宫外的表示生产有害效果,加重它的严格的表达式控制。解开 MSH1 效果的复杂性提供卓见进扳机植物特定, transgenerational 改编行为。 | Kamaldeep S. Virdi Yashitola Wamboldt Hardik Kundariya John D. Laurie Ido Keren K.R. Sunil Kumar Anna Block Gilles Basset Steve Luebker Christian Elowsky Philip M. Day Johnna L. Roose Terry M. Bricker Thomas Elthon Sally A. Mackenzie | 2016 | Molecular Plant2016，9，2： | 2 |
| 12 | Practice Parameters for the Management of Perianal Abscess and Fistula-in-Ano显示文摘 | Scott R. Steele Ravin Kumar Daniel L. Feingold Janice L. Rafferty W. Donald Buie | 2011 | Diseases of the Colon & Rectum2011，，： | 2 |
| 13 | Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism显示文摘 | K. Ganesh Kumar James L. Trevaskis Daniel D. Lam Gregory M. Sutton Robert A. Koza Vladimir N. Chouljenko Konstantin G. Kousoulas Pamela M. Rogers Robert A. Kesterson Marie Thearle Anthony W. Ferrante Randall L. Mynatt Thomas P. Burris Jesse Z. Dong Heathe | 2008 | Cell Metabolism2008，，： | 2 |
| 14 | The AIMS65 score compared with the Glasgow-Blatchford score in predicting outcomes in upper GI bleeding显示文摘 | Brian H. Hyett Marwan S. Abougergi Joseph P. Charpentier Navin L. Kumar Suzana Brozovic Brian L. Claggett Anne C. Travis John R. Saltzman | 2012 | Gastrointestinal Endoscopy2012，，： | 2 |
| 15 | Pharmacokinetics of the novel PAR-1 antagonist vorapaxar in patients with hepatic impairment显示文摘 | Paul Statkevich Teddy Kosoglou Richard A. Preston Bharath Kumar Fengjuan Xuan Craig Trusley James E. Schiller Ronald B. Langdon David L. Cutler | 2012 | European Journal of Clinical Pharmacology2012，，11： | 1 |
| 16 | Knockdown of RNA Binding Protein Musashi-1 Leads to Tumor Regression In Vivo显示文摘 | Sripathi M. Sureban Randal May Robert J. George Brian K. Dieckgraefe Howard L. McLeod Satish Ramalingam Kumar S. Bishnupuri Gopalan Natarajan Shrikant Anant Courtney W. Houchen | 2008 | Gastroenterology2008，，5： | 1 |
| 17 | Influence of milk and sugar on antioxidant potential of black tea显示文摘 | Vasundhara Sharma H. Vijay Kumar L. Jagan Mohan Rao | 2007 | Food Research International2007，，2： | 1 |
| 18 | Oncologic Colorectal Resection, Not Advanced Endoscopic Polypectomy, Is the Best Treatment for Large Dysplastic Adenomas显示文摘 | Joon Ho Jang Emre Balik Daniel Kirchoff Wouter Tromp Anjali Kumar Michael Grieco Daniel L. Feingold Vesna Cekic Linda Njoh Richard L. Whelan | 2012 | Journal of Gastrointestinal Surgery2012，，1： | 1 |
| 19 | The Frustrating Search for Arrhythmia Risk Stratifiers in Heart Failure Due to Nonischemic Cardiomyopathy显示文摘 | Richard L. Verrier Kapil Kumar Mark E. Josephson | 2007 | Journal of the American College of Cardiology2007，，： | 1 |
| 20 | The Effect of Multiple Doses of Ketoconazole or Rifampin on the Single- and Multiple-Dose Pharmacokinetics of Vorapaxar显示文摘 | Teddy Kosoglou Paul Statkevich Bharath Kumar Fengjuan Xuan James E. Schiller Amy O. Johnson-Levonas Sophia Young David L. Cutler | 2013 | Journal of Clinical Pharmacology2013，，5： | 1 |
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