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| 1 | Homocysteine enhances cell proliferation in vascular smooth muscle cells: role of p38 MAPK and p47phox显示文摘血 homocysteine 层次(hyperhomocysteinemia ) 的举起是为心血管的混乱的一个风险因素。homocysteine 由导致动脉粥样硬化的机制之一是在反应的氧种(ROS ) 支持脉管的光滑的肌肉细胞(VSMC ) 的增长依赖的举止。homocysteine 在 VSMC 通过 NAD (P) H oxidases 的激活导致 ROS 的生产,这被显示出。在这研究,我们调查了涉及 NAD (P) H oxidases 的激活的信号 transduction 小径。Homocysteine 在 VSMC 支持了 DNA 合成。由 N-acetyl-l-cysteine (一种抗氧化剂) 和 apocynin (NAD (P) H oxidases 的一个禁止者) 的 ROS 的抑制显著地在 VSMC 堵住了导致 homocysteine 的增长。Homocysteine 在 p38-mitogen-activated 蛋白质 kinase (p38 MAPK ) 的 phosphorylation 导致了快速的增加。p38 MAPK 接着由导致 p47phox 的 phosphorylation 激活 NAD (P) H oxidases,导致 ROS 的产生。ROS 导致了 Akt 的 phosphorylation,它为在 VSMC 的增长可能负责。这些调查结果证明 homocysteine 由激活 p38 MAPK 并且提高 p47phox 的 phosphorylation 在 VSMC 在 NAD (P) H oxidases 的活动导致增加。 | Tong Zou Weihong Yang Zongliu Hou Jiefu Yang | 2010 | Acta Biochimica et Biophysica Sinica2010，42，12： | 23 |
| 2 | Generation and Photocatalytic Activities of Bi@Bi2O3 Microspheres显示文摘合成 Bi@Bi2O3 microspheres 经由一条帮助微波的 solvothermal 线路被综合了。Bi@Bi2O3 microspheres 在范围有狭窄的尺寸分布 1.22.8 公里。葡萄糖作为 reductant 被选择,是的 BiCl3 铋来源,和乙烯乙二醇(例如) 作为在合成系统的溶剂。同样综合的样品被X光检查衍射( XRD )描绘,拉曼光谱学,X光检查光电子光谱学( XPS ),扫描电子显微镜学( SEM ),传播电子显微镜学( TEM ),粒子直径分发,精力散X光检查光谱学(版本),紫外可见(紫外力)光谱学,并且光致发光( PL )光谱学。Bi@Bi2O3 microspheres 的 photocatalytic 活动被玫瑰精 B (RhB ) 和甲基橘子(瞬间) 染料的 photodegradation 在紫外轻照耀下面评估。降级面对同样综合的 Bi@Bi2O3 microspheres 在 4 h 反应以后为瞬间为 RhB 和 100% 到达了 96.6% 。 | Xiangwen Liu Huaqiang Cao Jiefu Yin | 2011 | Nano Research2011，4，5： | 11 |
| 3 | Quantitative analysis on strengthening mechanism of ultra-thin hot strip of low carbon steel produced by CSP technique显示文摘Based on experimental data of positron annihilation technology, electrolytic dissolution technique, electron back-scattered pattern, etc. And by analysis the strengthening factors, the strengthening mechanism of ultra-thin hot strip of low carbon steel produced by CSP (Compact Strip Production) technique was investigated. The value of each strengthening mechanism and its contribution percentage to yield strength were achieved. The results show that refinement strengthening is the predominant strengthening mode; precipitation strengthening and dislocation strengthening are second to it, their contributions to yield strength are almost equal. | HaoYu YonglinKang XueyingXiong KeluWang JieFu GuijiangChen LiejunLi | 2004 | Journal of University of Science and Technology Beijing2004，11，5： | 8 |
| 4 | Novel roll effector based on zero-mass-flux dual synthetic jets and its flight test显示文摘The autonomous and controllable Dual Synthetic Jet Actuator(DSJA)is firstly integrated into the Unmanned Aerial Vehicle(UAV),and flight tests without the deflection of rudders are carried out to verify the viability of DSJA to control the attitudes of UAV during cruising.DSJA is improved into an actuator with two diaphragms and three cavities,which has higher energy levels.Actuators,differentially distributed on both sides of the wings,are installed on the trailing edge close to the wing tips.Flight tests,containing Differential Circulation Control(DCC)using double-side actuators,Positive Circulation Control(PCC)using left-side actuators and Negative Circulation Control(NCC)using right-side actuators,are implemented at cruising speed of 25 m/s.Results show that roll attitude control without rudders could be realized by DSJAs.DCC and NCC can generate the rightward roll and yaw angular velocity,prompting UAV to turn right.The stronger controlling ability can be achieved by DCC,with the maximum roll angular velocity of 15.62(°)/s.PCC can generate a rightward roll moment,but a leftward yaw moment will be produced at the same time.Leftward yaw induces the leftward rolling moment,which weakens the roll control effect,making UAV keep to yaw to the left with a small slope. | Zhenbing LUO Zhijie ZHAO Jiefu LIU Xiong DENG Mu ZHENG Hang YANG Qingyang CHEN Shiqing LI | 2022 | Chinese Journal of Aeronautics2022，35，8： | 7 |
| 5 | Clinical diagnosis and treatment of alpha-fetoprotein-negative small hepatic lesions显示文摘Objective: We examined 103 cases over the last five years and discussed diagnosis and treatment of alpha- fetoprotein (AFP)-negative small hepatic lesions. Background: Small hepatic lesions (less than 2 cm in diameter) usually have no typical imaging characteristics and therefore are difficult to diagnose, especially when AFP tests provide a negative result. Methods: A total of 103 patients with AFP-negative small hepatic lesions from January 2003 to December 2008 were retrospectively reviewed. Differential diagnosis was performed by digital subtraction angiography (DSA), dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), contrast-enhanced ultrasound (CEUS), or positron emission tomography-computed tomography (PET-CT) based on the multiplicity of lesions. Ninety-four patients with suspected cancers underwent partial hepatectomy. Clinical data were collected from hospital records and follow-up questionnaires. Results: Hepatocellular carcinoma (HCC) diagnostic sensitivity of DSA, DCE-MRI, CEUS and PET-CT was 88.2%, 93.9%, 88.9% and 88.9%, respectively. The surgery-related complication rate was 6.4%. Prognosis was good, with 1- and 3-year survival rates of 98.8% and 76.1%, respectively. Conclusions: DSA, DCE-MRI, CEUS and PET-CT are valuable for diagnosis of small hepatic lesions. Partial hepatectomy is a preferred surgical procedure. Surgery for small liver cancers usually has little risk and good prognosis, therefore it can be actively applied in suspected HCC cases. | Yiyao Xu Xin Lu Yilei Mao Xinting Sang Haitao Zhao Shunda Du Haifeng Xu Yongliang Sun Huayu Yang Tianyi Chi Zhiying Yang Shouxian Zhong Jiefu Huang | 2013 | Chinese Journal of Cancer Research2013，25，4： | 6 |
| 6 | Ag_(2)Se Complex Nanostructures with Photocatalytic Activity and Superhydrophobicity显示文摘Single-crystalline Ag_(2)Se complex nanostructures have been synthesized via a solvothermal route in which selenophene(C4H4Se)as a selenylation source reacts with AgNO3 at a temperature of 240°C.An orthorhombic phaseβ-Ag_(2)Se nanostructure was identified by X-ray diffraction(XRD),Raman spectroscopy,field emission scanning electron microscopy(FE-SEM),high resolution transmission electron microscopy(HRTEM),and photoluminescence(PL)spectroscopy.The wettability of the as-synthesizedβ-Ag_(2)Se nanostructure was studied by measurement of the water contact angle(CA).Static water CA values of over 150°were obtained,which can be attributed to theβ-Ag_(2)Se complex nanostructure having a combination of micro-and nanostructures.The superhydrophobic Ag_(2)Se nanostructure may find applications in self-cleaning.Additionally,the photocatalytic activity of the as-synthesizedβ-Ag_(2)Se nanostructure was evaluated by photodegradation of rhodamine B(RhB)dye under ultraviolet(UV)light irradiation. | Huaqiang Cao Yujiang Xiao Yuexiang Lu Jiefu Yin Baojun Li Shuisheng Wu Xiaoming Wu | 2010 | Nano Research2010，3，12： | 4 |
| 7 | Development and molecular analysis of a novel acetohydroxyacid synthase rapeseed mutant with high resistance to sulfonylurea herbicides显示文摘With the increasing promotion of simplified rapeseed cultivation in recent years,the development of cultivars with high resistance to herbicides is urgently needed.We previously developed M342,which shows sulfonylurea herbicide resistance,by targeting acetohydroxyacid synthase(AHAS),a key enzyme in branched-chain amino acid synthesis.In the present study,we used a progeny line derived from M342 for an additional round of ethyl methane sulfonate mutagenesis,yielding the novel mutant DS3,which harbored two mutations in AHAS genes and showed high sulfonylurea resistance.One mutation was the substitution Trp574 Leu,as in M342,according to Arabidopsis protein sequencing.The other site was a newly recognized substitution,Pro197 Leu.A KASP marker targeting Pro197 Leu was developed and reliably predicted the response to sulfonylurea herbicides in the F2 population.The combination of Trp574 Leu and Pro197 Leu in DS3 produced a synergistic effect that greatly increased herbicide resistance.Analysis of the protein structures of AHAS1 and AHAS3 in wild-type and single-gene mutant plants revealed three-dimensional protein conformational changes that could account for differences in herbicide resistance characteristics including toxicity tolerance,AHAS enzyme activity,and AHAS gene expression. | Yue Guo Changle Liu Weihua Long Jianqin Gao Jiefu Zhang Song Chen Huiming Pu Maolong Hu | 2022 | The Crop Journal2022，10，1： | 3 |
| 8 | Microstructure evolution and precipitation behavior of low carbon steel hot strips produced by CSP显示文摘The microstructures of low carbon steel before, during and after rolling deformation of each stand were observed using optical microscope. The result showed that the microstructures were very fine after six passes rolling deformation. The effect of the first stand reduction on microstructure refinement was very distinct. During the rolling process, with the increase of the accumulated strain, the microstructures would further refine, and the density of dislocation would increase at the same time. In continuous casting thin slabs and each finishing stand, lots of observed precipitates were mainly Al2O3 and MnS along the grain boundaries or in grains, which played an important role in the mechanical properties of the hot strips of low carbon steel produced by CSP (compact strip production) technology. | YonglinKang KeluWang HaoYu JieFu DeluLiu ZhongbingWang XuewenChen | 2004 | Journal of University of Science and Technology Beijing2004，11，4： | 3 |
| 9 | PhGRL2 Protein, Interacting with PhACO1, Is Involved in Flower Senescence in the Petunia显示文摘 | Yinyan Tan Juanxu Liu Fang Huang, Jiefu Guan, Shan Zhong, Na Tang, Ji Zhao, Weiyuan Yang Yixun Yu | 2014 | Molecular Plant2014，7，8： | 3 |
| 10 | Effect of renewed SS-cream on spinal somatosensory evokedpotential in rabbits显示文摘Aim:The effect of a renewed SS-cream (RSSC) on the treatment of premature ejaculation (PE) was evaluated and compared with the original SS-cream (OSSC).Methods: Sixty male white New Zealand rabbits,weighing 2.5kg-3.0kg,were divided at random into 3 groups:the RSSC,OSSC and placebo groups.The spinal somatosensory evoked potential (SSEP) elicited by electric stimulation of the glans penis with disk electrode was investigated with an electrophysiograph (Poseidomn,Shanghai,China) before and 10,30 and 60 min after drug or placebo application on the glans.The Onset and the N1 latencies and the amplitude of SSEP were recorded and analyzed. Results:There was no significant difference (P>0.05) in the mean Onset and N1 latency of SSEP among the 3 groups before drug application.Compared with the pre-application value,the mean Onset and N 1 latencies in the RSSC and OSSC groups were significantly prolonged at 10,30 and 60 min after treatment (P<0.05),while they were not significantly changed (P>0.05) in the placebo group.The mean Onset latency of RSSC at 10 and 30 min and that of OSSC at 30 min were significantly delayed (P<0.05) compared with the placebo group.The mean N1 latency of RSSC at 30 and 60 min and that of OSSC group at 30 min were also significantly delayed (P<0.05).Conclusion:RSSC delays the latencies of SSEP,suggesting a local desensitizing effect on the sensory receptor of the glans penis dorsal nerve,which provides the potential for PE treatment.The desensitizing effect of RSSC is higher than that of OSSC.( Asian J Androl 2004 Mar;6:15-18) | LongTian Zhong-ChengXin HuaXin JieFu Yi-MingYuan Wu-JiangLiu ChunYang | 2004 | Asian Journal of Andrology2004，6，1： | 2 |
| 11 | Polymer complexation for functional fibers显示文摘Polymer complex is a polymer association of different polymers with good miscibility resulting from the relatively strong intermolecular interactions or stereo match effect between polymer chains. Polymer complexes have been utilized in various fields, such as food, biomedical, cosmetic, and pharmacy. Fiber is one of the most important material forms, and shaping polymer complex into fiber will further extend its applications. This review briefly introduces the fundamentals of polymer complex, and then demonstrates the main approaches to produce polymer complex fibers(PCFs). Followed by, the modification of fibers with polymer complexes is presented. Finally, the applications of PCFs and the polymer complex modified fibers are provided, and the prospect of polymer complexation for fibers is discussed properly. | HUANG WenTao LIU DeZhong LI JieFu ZHU LiPing YANG ShuGuang | 2019 | Science China(Technological Sciences)2019，62，6： | 2 |
| 12 | Functionalization-Directed Stabilization of Hydrogen-Bonded Polymer Complex Fibers:Elasticity and Conductivity显示文摘Elastic,repairable and conductive fibers are desirable in the newly emerging field of soft electronic and wearable devices.Here,we design a multifunctional fiber by incorporation of different components to optimize its performance.The combination of the poly(acrylic acid)(PAA)and poly(ethylene oxide)(PEO)through hydrogen bonding endows the fiber with high elasticity and repairability.Polydopamine(PDA)significantly increases the stability of the fiber,thus the fiber will not dissolve in alkaline solutions and still keep the repairable ability.The fiber shows a reversible swelling-shrinking property as pH values go up and down.Further,the conductive component,carbon nanotube,is adsorbed at the swelling state and then is fastened with fiber shrinking. | Jiefu Li Jiaxing Sun Di Wu Wentao Huang Meifang Zhu Elsa Reichmanis Shuguang Yang | 2019 | Advanced Fiber Materials2019，1，1： | 2 |
| 13 | Identification of prognostic biomarkers in hepatitis B virus-related hepatocellular carcinoma and stratification by integrative multi-omics analysis显示文摘 | Ruoyu Miao Haitao Luo Huandi Zhou Guangbing Li Dechao Bu Xiaobo Yang Xue Zhao Haohai Zhang Song Liu Ying Zhong Zhen Zou Yan Zhao Kuntao Yu Lian He Xinting Sang Shouxian Zhong Jiefu Huang Yan Wu Rebecca A. Miksad Simon C. Robson Chengyu Jiang Yi Zhao Haita | 2014 | Journal of Hepatology2014，，： | 2 |
| 14 | Adoptive Transfer of Human Gingiva‐Derived Mesenchymal Stem Cells Ameliorates Collagen‐Induced Arthritis via Suppression of Th1 and Th17 Cells and Enhancement of Regulatory T Cell Differentiation显示文摘 | Maogen Chen Wenru Su Xiaohong Lin Zhiyong Guo Julie Wang Qunzhou Zhang David Brand Bernhard Ryffel Jiefu Huang Zhongmin Liu Xiaoshun He Anh D. Le Song Guo Zheng | 2013 | Arthritis & Rheumatism2013，，5： | 1 |
| 15 | Minimally invasive technique of triple anterior screw fixation for an acute combination at-las-axis fracture:case report and literature review显示文摘 | Dean Q Jiefu S Jie W | | 0，，02： | 1 |
| 16 | Orthotopic liver transplantation hepatocellular carcinoma显示文摘 | Huang Jiefu Lu Minqiang He xiaoshun | 2001 | Chin J Gen Surg2001，16，1： | 1 |
| 17 | Ethical and legislative perspectives on liver transplantation in the People' s Republic of China 显示文摘 | Huang Jiefu | 2007 | Liver Transplant2007，13，2： | 1 |
| 18 | Grain refinement of low carbon steel produced by CSP process显示文摘In comparison with conventional production for hot strips, compact strip production (CSP) brings about some new microstructural phenomena. Investigations were carried out to clarify the grain refinement mechanism of low carbon steel strips produced by the EAF-CSP process. Samples, obtained from the same rolling stock during continuous rolling, were examined through SEM,TEM and XEDS. Thin slabs have a dominant columnar structure and the spacing of the secondary dendrite arms ranges from 90 to ~125 μm. The average grain sizes for the central area of the samples from the 1st to 6th pass are 41.6, 25.2, 21.4, 20.2, 13.1, 6.7 μm,respectively. Large number of nanometer oxide and sulfide have been found in the low carbon steel produced by the CSP process.The grain refinement mechanism can be summarized as follows: finer solidification structure of the thin slab; austenite recrystallization at higher temperature and stain accumulation at lower temperature caused by the great reduction of single rolling pass during continuous rolling; nano-scaled precipitates of sulfide and oxide which drag grain boundaries of austenite or ferrite to prevent the grain coarsening. | XiangdongHuo DeluLiu YuanliWang NanjingChen YonglinKang JieFu | 2004 | Journal of University of Science and Technology Beijing2004，11，2： | 1 |
| 19 | Minimally invasive technique of triple anterior screw fixation for an acute combination atlas - axis fracture: case report and literature review 显示文摘 | Dean Q Jiefu S Jie W | 2010 | Spinal Cord2010，2，： | 1 |
| 20 | An ultradense genetic recombination map for Brassica napus, consisting of 13551 SRAP markers显示文摘 | Zudong Sun Zining Wang Jinxing Tu Jiefu Zhang Fengqun Yu Peter B. E. McVetty Genyi Li | 2007 | Theoretical and Applied Genetics2007，，8： | 1 |
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