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| 1 | A Text Sentiment Classification Modeling Method Based on Coordinated CNN-LSTM-Attention Model显示文摘The major challenge that text sentiment classification modeling faces is how to capture the intrinsic semantic, emotional dependence information and the key part of the emotional expression of text. To solve this problem, we proposed a Coordinated CNNLSTM-Attention(CCLA) model. We learned the vector representations of sentence with CCLA unit. Semantic and emotional information of sentences and their relations are adaptively encoded to vector representations of document.We used softmax regression classifier to identify the sentiment tendencies in the text. Compared with other methods, the CCLA model can well capture the local and long distance semantic and emotional information.Experimental results demonstrated the effectiveness of CCLA model. It shows superior performances over several state-of-the-art baseline methods. | ZHANG Yangsen ZHENG Jia JIANG Yuru HUANG Gaijuan CHEN Ruoyu | 2019 | Chinese Journal of Electronics2019，28，1： | 32 |
| 2 | Research progress in the heat resistance, toughening and filling modification of PLA显示文摘Due to its high strength, high modulus, excellent clarity, good biodegradability and biocompatibility, poly(lactic acid)(PLA), a bio-based thermoplastic polyester, has evolved into a competitive commodity material with potential to replace conventional petrochemical-based polymers. However, the wide applications of PLA have been hampered by its native drawbacks, such as low heat distortion temperature(HDT), inherent brittleness and relatively high cost. In recent years, researchers have devoted to breaking above-mentioned bottleneck and attempted to extend the application of PLA. This review will summarize recent work about the modification of PLA, especially focusing on enhancing HDT, toughening and reducing cost. | Yong Yang Lisheng Zhang Zhu Xiong Zhaobin Tang Ruoyu Zhang Jin Zhu | 2016 | Science China Chemistry2016，59，11： | 18 |
| 3 | IL-23-induced macrophage polarization and its pathological roles in mice with imiquimod-induced psoriasis显示文摘Macrophages acquire distinct phenotypes during tissue stress and inflammatory responses.Macrophages are roughly categorized into two different subsets named inflammatory M1 and anti-inflammatory M2 macrophages.We herein identified a unique pathogenic macrophage subpopulation driven by IL-23 with a distinct gene expression profile including defined types of cytokines.The freshly isolated resting mouse peritoneal macrophages were stimulated with different cytokines in vitro,the expression of cytokines and chemokines were detected by microarray,real-time PCR,ELISA and multiple colors flow cytometry.Adoptive transfer of macrophages and imiquimod-induced psoriasis mice were used.In contrast to M1-and M2-polarized macrophages,IL-23-treated macrophages produce large amounts of IL-17A,IL-22and IFN-γ.Biochemical and molecular studies showed that IL-23 induces IL-17A expression in macrophages through the signal transducer and activator of transcription 3(STAT3)-retinoid related orphan receptor-γ T (RORyT)pathway.T-bet mediates the IFN-γ production in IL-23-treated macrophages.Importantly,IL-23-treated macrophages signifi- cantly promote the dermatitis pathogenesis in a psoriasis-like mouse model.IL-23-treated resting macrophages express a distinctive gene expression prolife compared with M1 and M2 macrophages.The identification of IL-23-induced macrophage polarization may help us to understand the contribution of macrophage subpopulation in Th17-cytokines-related pathogenesis. | Yuzhu Hou Linnan Zhu Hongling Tian Hai-Xi Sun Ruoyu Wang Lianfeng Zhang Yong Zhao | 2018 | Protein & Cell2018，9，12： | 16 |
| 4 | Endocrine role of bone in the regulation of energy metabolism显示文摘Bone mainly functions as a supportive framework for the whole body and is the major regulator of calcium homeostasis and hematopoietic function.Recently,an increasing number of studies have characterized the significance of bone as an endocrine organ,suggesting that bone-derived factors regulate local bone metabolism and metabolic functions.In addition,these factors can regulate global energy homeostasis by altering insulin sensitivity,feeding behavior,and adipocyte commitment.These findings may provide a new pathological mechanism for related metabolic diseases or be used in the diagnosis,treatment,and prevention of metabolic diseases such as osteoporosis,obesity,and diabetes mellitus.In this review,we summarize the regulatory effect of bone and bone-derived factors on energy metabolism and discuss directions for future research. | Ruoyu Zhou Qiaoyue Guo Ye Xiao Qi Guo Yan Huang Changjun Li Xianghang Luo | 2021 | Bone Research2021，9，4： | 11 |
| 5 | Regulation of the inflammatory cycle by a controllable release hydrogel for eliminating postoperative inflammation after discectomy显示文摘Surgery is the final choice for most patients with intervertebral disc degeneration(IDD).Operation-caused trauma will cause inflammation in the intervertebral disc.Serious inflammation will cause tissue defects and induce tissue degeneration,IDD recurrence and the occurrence of other diseases.Therefore,we proposed a scheme to treat recurrence after discectomy by inhibiting inflammation with an aspirin(ASP)-loaded hydrogel to restore the mechanical stability of the spine and relieve local inflammation.ASP-liposomes(ASP-Lips)were incorporated into a photocrosslinkable gelatin-methacryloyl(GelMA)via mixing.This material can effectively alleviate inflammation by inhibiting the release of high mobility group box 1(HMGB1)from the nucleus to the cytoplasm.We further assessed the expression of inflammatory cytokines,such as interleukin 6(IL-6)and tumor necrosis factor-α(TNF-α),and degeneration-related factors,such as type II collagen(COL-2),Aggrecan,matrix metallopeptidases-3(MMP-3),MMP-13,a disintegrin and metalloproteinase with thrombospondin motifs-4(ADAMTS-4)and ADAMTS-5 in rat nucleus pulpous cells.The level of IDD was analyzed through H&E,safranin-O staining and immunohistochemistry in rabbit samples.In vitro,we found that ASP-Lip@GelMA treatment significantly decreased inflammatory cytokines,MMP-3 and-13,and ADAMTS-4 and-5 and up-regulated COL-2 and Aggrecan via the inhibited release of HMGB-1 from the nucleus.In vivo,ASP-Lip@GelMA can effectively inhibit inflammation of local tissue after disc surgery and fill local tissue defects.This composite hydrogel system is a promising way to treat the recurrence of IDD after surgery without persistent complications. | Yu Liu Jiacheng Du Peng Peng Ruoyu Cheng Jiayi Lin Congxin Xu Huilin Yang Wenguo Cui Haiqing Mao Yuling Li Dechun Geng | 2021 | Bioactive Materials2021，6，1： | 6 |
| 6 | FluxExplorer: A general platform for modeling and analyses of metabolic net-works based on stoichiometry显示文摘Stoichiometry-based analyses of meta- bolic networks have aroused significant interest of systems biology researchers in recent years. It is necessary to develop a more convenient modeling platform on which users can reconstruct their network models using completely graphical operations, and explore them with powerful analyzing modules to get a better understanding of the properties of metabolic systems. Herein, an in silico platform, FluxExplorer, for metabolic modeling and analyses based on stoichiometry has been developed as a publicly available tool for systems biology research. This platform integrates various analytic approaches, in- cluding flux balance analysis, minimization of meta- bolic adjustment, extreme pathways analysis, shadow prices analysis, and singular value decom- position, providing a thorough characterization of the metabolic system. Using a graphic modeling process, metabolic networks can be reconstructed and modi- fied intuitively and conveniently. The inconsistencies of a model with respect to the FBA principles can be proved automatically. In addition, this platform sup- ports systems biology markup language (SBML). FluxExplorer has been applied to rebuild a metabolic network in mammalian mitochondria, producing meaningful results. Generally, it is a powerful and very convenient tool for metabolic network modeling and analysis. | LUO Ruoyu LIAO Sha ZENG Shaoqun LI Yixue LUO Qingming | 2006 | Chinese Science Bulletin2006，51，6： | 6 |
| 7 | 美国麻醉专科护士的发展与资格认证及对我国的启示显示文摘通过综述美国麻醉专科护士的历史发展及现状,包括资格认证、课程设置及考核、执业范围及使用、工作内容及成效的内容介绍,分析了美国麻醉专科护士的经验与教训,结合我国麻醉专科护士现状,分析我国的借鉴方面,提出现阶段我国麻醉专科护士规范化发展的建议。 | 刘尚昆 Ruoyu Zhao 徐蓉 | 2018 | 中华现代护理杂志2018，24，36： | 6 |
| 8 | Th and Treg response induced by Aspergillusfumigatus pulsed dendritic cells in vitro显示文摘 | Wang Runchao Wan Zhe Li Ruoyu | 2014 | Chinese Medical Journal2014，，20： | 6 |
| 9 | On the viscosity of magnetic fluid with low and moderate solid fraction显示文摘The design of a pressurized capillary rheometer operating at prescribed temperature is described to measure the viscosity of magnetic fluids(MFs) containing Fe3O4 magnetic nanoparticles(MNPs).The equipment constant of the rheometer was obtained using liquids with predetermined viscosities.Experimentally measured viscosities were used to evaluate different equations for suspension viscosities.Deviation of measured suspension viscosities from the Einstein equation was found to be basically due to the influence of spatial distribution and aggregation of Fe3O4 MNPs.By taking account of the coating layer on MNPs and the aggregation of MNPs in MFs,a modified Einstein equation was proposed to fit the experimental data.Moreover,the influence of external magnetic field on viscosity was also taken into account.Viscosities thus predicted are in good agreement with experimental data.Temperature effect on suspension viscosity was shown experimentally to be due to the shear-thinning behavior of the MFs. | Zhiqiang Ren Yanping Han Ruoyu Hong Jianmin Ding Hongzhong Li | 2008 | Particuology2008，6，3： | 5 |
| 10 | Comparison of schemes for preparing magnetic Fe_3O_4 nanoparticles显示文摘Magnetic Fe3O4 nanoparticles were prepared by means of coprecipitation using NH3·H2O in water and in alcohol, and using NaOH in water. A series of instruments such as SEM, TEM, HRTEM, FT-IR, XRD and VSM were used to characterize the properties of the magnetic nanoparticles. The results indicated that the magnetism of Fe3O4 nanoparticles synthesized using NH3·H2O in water was the highest, although the reaction time was the longest. The process using NaOH in water was the simplest and the reaction time was the shortest, but the particle characteristics were inferior to those of the other two methods. The mean size of magnetic Fe3O4 nanoparticles prepared by coprecipitation in alcohol was the smallest among the three, but the nanoparticles aggregated severely. The magnetic Fe3O4 nanoparticles were coated with oleic acid using saturated sodium oleate, and the polarity of the surface-modified nanoparticles was measured. Fe3O4 nanoparticles prepared using NH3·H2O, not NaOH, could be coated successfully and thoroughly. | Ruoyu Hong Jianhua Li Jian Wang Hongzhong Li | 2007 | China Particuology2007，5，1： | 5 |
| 11 | Fast and uniform growth of graphene glass using confined-flow chemical vapor deposition and its unique applications显示文摘常规玻璃上的高质量的 graphene 的快、一致的生长为 graphene 玻璃的实际应用程序是很重要的。我们此处为 graphene 玻璃的高效率的制造报导一条范围流动化学药品蒸汽免职(CVD ) 途径。我们的途径的特色是 2-4 m 的制造在玻璃底层上面的宽差距,与很多的跌倒块;这差距被发现显著地增加在对方之间并且与玻璃表面的碳先锋和反应碎片的碰撞概率。作为结果, graphene 玻璃的生长率显著地增加了,和在象与那些相比的生长质量和在常规煤气的流动 CVD 技术的一致性的改进。这些高质量的 graphene 眼镜与以前报导的那些相比以许多更高的 defogging 速度和更高的稳定性展出了优秀 defogging 表演。graphene 蓝宝石玻璃被发现是为种制服和极端光滑的铝氮化物的理想的底层没有缓冲区层的乏味的免职前的薄电影。介绍范围流动 CVD 途径为 graphene 玻璃的大量生产提供一条简单、便宜的线路,它被相信支持各种各样的 graphene 眼镜的实际应用。 | Zhaolong Chen Baolu Guan Xu-dong Chen Qing Zeng Li Lin Ruoyu Wang Manish Kr. Priydarshi Jingyu Sun Zhepeng Zhang Tongbo Wei Jinmin LI Yanfeng Zhang Yingying Zhang Zhongfan Liu | 2016 | Nano Research2016，9，10： | 5 |
| 12 | Combined and synergistic effects of climate change and urbanization on water quality in the Wolf Bay watershed,southern Alabama显示文摘This study investigated potential changes in flow, total suspended solid(TSS) and nutrient(nitrogen and phosphorous) loadings under future climate change, land use/cover(LULC)change and combined change scenarios in the Wolf Bay watershed, southern Alabama,USA. Four Global Circulation Models(GCMs) under three Special Report Emission Scenarios(SRES) of greenhouse gas were used to assess the future climate change(2016–2040). Three projected LULC maps(2030) were employed to reflect different extents of urbanization in future. The individual, combined and synergistic impacts of LULC and climate change on water quantity/quality were analyzed by the Soil and Water Assessment Tool(SWAT).Under the 'climate change only' scenario, monthly distribution and projected variation of TSS are expected to follow a pattern similar to streamflow. Nutrients are influenced both by flow and management practices. The variation of Total Nitrogen(TN) and Total Phosphorous(TP) generally follow the flow trend as well. No evident difference in the N:P ratio was projected. Under the 'LULC change only' scenario, TN was projected to decrease,mainly due to the shrinkage of croplands. TP will increase in fall and winter. The N:P ratio shows a strong decreasing potential. Under the 'combined change' scenario, LULC and climate change effect were considered simultaneously. Results indicate that if future loadings are expected to increase/decrease under any individual scenario, then the combined change will intensify that trend. Conversely, if their effects are in opposite directions, an offsetting effect occurs. Science-based management practices are needed to reduce nutrient loadings to the Bay. | Ruoyu Wang Latif Kalin | 2018 | Journal of Environmental Sciences2018，30，2： | 5 |
| 13 | Sulfonate group modified Ni catalyst for highly efficient liquid-phase selective hydrogenation of bio-derived furfural显示文摘The liquid-phase furfural(FAL) hydrogenation to furfuryl alcohol(FOL) and tetrahydrofurfuryl alcohol(THFOL) was investigated using sulfonate group(-SO3 H) grafted activated carbon(AC) supported Ni catalyst, which was prepared and activated simultaneously by liquid phase reduction method. This functionalized nickel catalyst demonstrated an enhanced catalytic performance for selective hydrogenation of FAL, in which almost 100% FOL(<80℃) and THFOL(>100℃) selectivity with complete conversion was obtained, respectively. More importantly, the conversion of transfer hydrogenation of FAL to FOL also can reach almost 100% under optimal conditions(140℃, 4.0 h). The effect of-SO3 H was evaluated and systematically analyzed by the combination of reaction performance and physico-chemical characterizations. Cycling test proved the prepared catalyst could be recycled and reused for several times without noticeably reducing catalytic activity of hydrogenation. | Wanbing Gong Chun Chen Haojie Wang Ruoyu Fan Haimin Zhang Guozhong Wang Huijun Zhao | 2018 | Chinese Chemical Letters2018，29，11： | 4 |
| 14 | Conodont and Ammonoid Biostratigraphies around the Permian-Triassic Boundary from the Jianzishan of South China显示文摘Conodonts and ammonoids have played significant roles in the Permian-Triassic timescale.In order to uncover the nature of the Permian-Triassic mass extinction and subsequent recovery,we studied conodont and ammonoid biostratigraphies around the Permian-Triassic boundary from Jianzishan of Hubei,South China.A total of four conodont zones and two ammonoid beds are recognized.In ascending order,the conodont zones are Late Changhsingian Clarkina changxingensis Zone,Clarkina yini Zone and Griesbachian Hindeodus parvus Zone,Hindeodus postparvus Zone;the ammonoid beds are Late Griesbachian Ophiceras beds and Early Dienerian Ussuridiscus varaha beds.At Jianzishan,Ophiceras beds are stratigraphically younger than Hindeodus parvus Zone,but it is likely to be the same level with Hindeodus postparvus Zone.The Lower Dienerian in Bed 8 in this section is characterized by ammonoid Ussuridiscus varaha beds,which is associated with many Late Griesbachian conodonts including Hindeodus postparvus,Hindeodus praeparvus,Hindeodus typicalis,Hindeodus pisai,Hindeodus latidentatus,Hindeodus parvus,Hindeodus anterodentatus and Isarcicella turgida,indicating these conodont species could pass through the Griesbachian-Dienerian boundary and occurred in the Early Dienerian oceans. | Ruoyu Bai Xu Dai Haijun Song | 2017 | Journal of Earth Science2017，28，4： | 4 |
| 15 | Slip behavior of Bi-modal structure in a metastable β titanium alloy during tensile deformation显示文摘β titanium alloys with bi-modal structure which exhibit improved strength-ductility combination and fatigue property are widely used in aviation and aerospace industry.However,owing to the small size of primary α(αp) and nano-scaled multi variant distribution of secondary α platelets(αs),investigating the deformation behavior is really a challenging work.In this work,by applying transmission electron microscopy(TEM),the slip behavior in αp and transformed β matrix with different tensile strain was studied.After α/β solution treatment,the initial dislocation slips on {110} plane with <1 1 1> direction in β matrix.During furtherdeformation,(110),(101) and(1 1 2) multi slip is generated which shows a long straight cro s sing configuration.Dislocation cell is exhibited in β matrix at tensile strain above 20 %.Diffe rent from the solid solution treated sample,high density wavy dislocations are generated in transformedβ matrix.High fraction fine as hinders dislocation motion in β matrix effectively which in turn dominates the strength of the alloy.In primary α phase(αp),a core-shell structure is formed during deformation.Both pyramidal a+c slip and prismatic/basal a slip are generated in the shell layer.In core region,plastic deformation is governed by prismatic/basal a slip.Formation of the core-shell structure is the physical origin of the improved ductility.On one hand,the work hardening layer(shell) improves the strength of αp,which could deform compatibly with the hard transformed β matrix.Meanwhile,the center area(core) deforms homogeneously which will sustain plastic strain effectively and increase the ductility.This paper studies the slip behavior and reveals the origin of the improved strength-ductility combination in Bi-modal structure on a microscopic way,which will give theoretical advises for developing the next generation high strength β titanium alloys. | Wenguang Zhu Changsheng Tan Ruoyu Xiao Qiaoyan Sun Jun Sun | 2020 | Journal of Materials Science & Technology2020，54，22： | 4 |
| 16 | Climate change induced eutrophication of cold-water lake in an ecologically fragile nature reserve显示文摘Aquatic ecosystem sustainability around the globe is facing crucial challenges because of increasing anthropogenic and natural disturbances. In this study, the Tianchi Lake, a typical cold-water lake and a UNESCO/MAB(Man and Biosphere) nature reserve located in high latitude and elevation with the relatively low intensity of human activity was chosen as a system to examine the linkages between climate change and eutrophication. As a part of the UNESCO Bogda Man and Biosphere Reserve, Tianchi Lake has been well preserved for prevention from human intervention, but why has it been infected with eutrophication recent years? Our results show that climate change played a significant role in the eutrophication in the Tianchi Lake. Increased temperature, changed precipitation pattern and wind-induced hydrodynamic fluctuations in the summer season were suggested to make a major contribution to the accelerated eutrophication. The results also showed that the local temperature and precipitation changes were closely linked to the large-scale atmospheric circulation, which opens the door for the method to be applied in other regions without local climatic information. This study suggests that there is an urgent need to take into consideration of climate change adaptation into the conservation and management of cold-water lakes globally. | Xiaotian Lu Yonglong Lu Deliang Chen Chao Su Shuai Song Tieyu Wang Hanqin Tian Ruoyu Liang Meng Zhang Kifayatullah Khan | 2019 | Journal of Environmental Sciences2019，31，1： | 4 |
| 17 | A CORRELATION EQUATION FOR CALCULATING INCLINED JET PENETRATION LENGTH IN A GAS-SOLID FLUIDIZED BED显示文摘Numerical simulation of gas-solid flow in a two-dimensional fluidized bed with an inclined jet was performed. The numerical model is based on the two-fluid model of gas and solids phase in which the solids constitutive equations are based on the kinetic theory of granular flow. The improved ICE algorithm, which can be used for both low and high-velocity fluid flow, were used to solve the model equations. The mechanism of jet formation was analyzed using both numerical simulations and experiments. The emergence and movement of gas bubbles were captured numerically and experimentally. The influences of jet velocity, nozzle diameter, nozzle inclination and jet position on jet penetration length were obtained. A semi-empirical expression was derived and the parameters were correlated from experimental data. The correlation equation, which can be easily used to obtain the inclined jet penetration length, was compared with our experimental data and published correlation equations. | Ruoyu Hong Haibing Li Jianmin Ding Hongzhong Li | 2005 | China Particuology2005，3，5： | 3 |
| 18 | N, F?Codoped Microporous Carbon Nanofibers as Efficient Metal?Free Electrocatalysts for ORR显示文摘Currently, the oxygen reduction reaction(ORR) mainly depends on precious metal platinum(Pt) catalysts. However, Pt-based catalysts have several shortcomings, such as high cost, scarcity, and poor long-term stability. Therefore, development of e cient metal-free electrocatalysts to replace Pt-based electrocatalysts is important. In this study, we successfully prepared nitrogen-and fluorinecodoped microporous carbon nanofibers(N, F-MCFs) via electrospinning polyacrylonitrile/polyvinylidene fluoride/polyvinylpyrrolidone(PAN/PVDF/PVP) tricomponent polymers followed by a hydrothermal process and thermal treatment, which was achieved for the first time in the literature. The results indicated that N, F-MCFs exhibit a high catalytic activity(E_(onset): 0.94 V vs. RHE, E_(1/2): 0.81 V vs. RHE, and electron transfer number: 4.0) and considerably better stability and methanol tolerance for ORR in alkaline solutions as compared to commercial Pt/carbon(Pt/C, 20 wt%) catalysts. Furthermore, in acidic media, N, F-MCFs showed a four-electron transfer pathway for ORR. This study provides a new strategy for in situ synthesis of N, F-MCFs as highly e cient metal-free electrocatalysts for ORR in fuel cells. | Tianle Gong Ruoyu Qi Xundao Liu Hong Li Yongming Zhang | 2019 | Nano-Micro Letters2019，11，1： | 3 |
| 19 | Oscillating Cellulase Adsorption and Enhanced Lignocellulose Hydrolysis upon Ultrasound Treatment显示文摘We investigated the effects of ultrasound treatment on cellulase adsorption and lignocellulose hydrolysis.The activity of cellulase remained constant upon lowpower ultrasound treatment(<120 W) and decreased using high-power ultrasound(>280 W).Oscillating cellulase adsorption occurred upon ultrasound treatment with any intensity.The maxima for desorption and adsorption were41.9 and 83.1%,respectively,during 1 h of 90 W ultrasound treatment at 50 °C.A comparison between the shorttime with long-time ultrasound experiments indicated that ultrasound treatment tended to desorb cellulase from substrate.However,ultrasound treatment also led to further surface erosion of biomass,which increased cellulase accessibility.These joint actions of ultrasound treatment induced the oscillating adsorption of cellulase.The increase in cellulase accessibility caused by ultrasound treatment led to a significant enhancement in lignocellulose hydrolysis. | Rongxin Su Renjun Yang Yang Jifeng Ruoyu Du Renliang Huang Wei Qi Zhimin He | 2017 | Transactions of Tianjin University2017，23，1： | 3 |
| 20 | The role and its mechanism of intermittent fasting in tumors:friend or foe?显示文摘Intermittent fasting(IF)is becoming a prevailing topic worldwide,as it can cause changes in the body’s energy metabolism processes,improve health,and affect the progression of many diseases,particularly in the circumstance of oncology.Recent research has shown that IF can alter the energy metabolism of tumor cells,thereby inhibiting tumor growth and improving antitumor immune responses.Furthermore,IF can increase cancer sensitivity to chemotherapy and radiotherapy and reduce the side effects of these traditional anticancer treatments.IF is therefore emerging as a promising approach to clinical cancer treatment.However,the balance between long-term benefits of IF compared with the harm from insufficient caloric intake is not well understood.In this article,we review the role of IF in tumorigenesis and tumor therapy,and discuss some scientific problems that remain to be clarified,which might provide some assistance in the application of IF in clinical tumor therapy. | Xu Zhao Jing Yang Ruoyu Huang Mengmeng Guo Ya Zhou Lin Xu | 2021 | Cancer Biology & Medicine2021，18，1： | 3 |
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