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| 1 | ERCP in acute pancreatitis:What takes place in routine clinical practice?显示文摘AIM:To evaluate the data from a survey carried out in Italy regarding the endoscopic approach to acute pancreatitis in order to obtain a picture of what takes place after the release of an educational project on acute pancreatitis sponsored by the Italian Association for the Study of the Pancreas.METHODS:Of the 1 173 patients enrolled in our survey,the most frequent etiological category was biliary forms(69.3%) and most patients had mild pancreatitis(85.8%).RESULTS:344/1 173(29.3%) underwent endoscopic retrograde cholangiopancreatography(ERCP).The mean interval between the onset of symptoms and ERCP was 6.7 ± 5.0 d;only 89 examinations(25.9%) were performed within 72 h from the onset of symptoms.The main indications for ERCP were suspicion of common bile duct stones(90.3%),jaundice(44.5%),clini cal worsening of acute pancreatitis(14.2%) and cho langitis(6.1%).Biliary and pancreatic ducts were visua lized in 305 patients(88.7%) and in 93 patients(27.0%) respectively.The success rate in obtaining a cholangio gram was statistically higher(P = 0.003) in patients with mild acute pancreatitis(90.6%) than in patients with severe disease(72.2%).Biliary endoscopic sphinc terotomy was performed in 295 of the 305 patients(96.7%) with no difference between mild and severe disease(P = 0.985).ERCP morbidity was 6.1% and mortality was 1.7%;the mortality was due to the complications of acute pancreatitis and not the endoscopic procedure.CONCLUSION:The results of this survey,as with those carried out in other countries,indicate a lack of compliance with the guidelines for the indications for interventional endoscopy. | Armando Gabbrielli Raffaele Pezzilli Generoso Uomo Alessandro Zerbi Luca Frulloni Paolo De Rai Laura Castoldi Guido Costamagna Claudio Bassi Valerio Di Carlo | 2010 | World Journal of Gastrointestinal Endoscopy2010，2，9： | 14 |
| 2 | Determinant-Based Classification of Acute Pancreatitis Severity: An International Multidisciplinary Consultation显示文摘 | E. Patchen Dellinger Christopher E. Forsmark Peter Layer Philippe Lévy Enrique Maraví-Poma Maxim S. Petrov Tooru Shimosegawa Ajith K. Siriwardena Generoso Uomo David C. Whitcomb John A. Windsor | 2012 | Annals of Surgery2012，，6： | 7 |
| 3 | VHL and HIF-1α: gene variations and prognosis in early-stage clear cell renal cell carcinoma显示文摘 | Francesca Lessi Chiara Maria Mazzanti Sara Tomei Claudio Cristofano Andrea Minervini Michele Menicagli Alessandro Apollo Lorenzo Masieri Paola Collecchi Riccardo Minervini Marco Carini Generoso Bevilacqua | 2014 | Medical Oncology2014，，3： | 2 |
| 4 | 基于局部因素和全身因素对急性胰腺炎严重程度的新分级——概要与解读显示文摘急性胰腺炎严重程度的准确分级对于临床实践和研究十分重要。在临床实践中,准确的分型有助于正确地评估疾病的严重程度,监测疾病的发展,制定治疗策略。而临床研究中,准确的分型对于患者的正确入组、实验结果的有效性都有很大影响。一个多世纪以来,急性胰腺炎的严重程度被简单地分为轻型和重型,而且对于轻型和重型的定义尚未统一。近年来,研究发现重型胰腺炎又有不同的亚组,而不同亚组患者的预后有很大差异,轻型和重型二分法的局限性慢慢显现。 | 李维勤 张璐瑶 黎介寿 E.Patchen Dellinger Christopher E.Forsmark Peter Layer Philippe L'evy Enrique Maravi-Poma Maxim S.Petrov Tooru Shimosegawa Ajith K.Siriwardena Generoso Uomo David C.Whitcomb John A.Windsor | 2014 | 浙江医学2014，36，10： | 2 |
| 5 | Comparison of two dosing regimens of gabexate in the prophylaxis of post-ERCP pancreatitis显示文摘 | Enzo Masci Giorgio Cavallini Alberto Mariani Luca Frulloni Pier Alberto Testoni Simona Curioni Alberto Tittobello Generoso Uomo Guido Costamagna Sandro Zambelli Gianpiero Macarri Paolo Innocenti Carola Dragonetti | 2003 | The American Journal of Gastroenterology2003，，10： | 2 |
| 6 | Aerosol effect on cloud droplet size monitored from satellite显示文摘 | Breon F M Generoso T D | 2002 | Science2002，295，： | 1 |
| 7 | Brain-blood barrier breakdown and pro-inflammatory mediators in neonate rats submitted meningitis by Streptococcus pneumonia 显示文摘 | Barichello T Fagundes GD Generoso JS | 2012 | Brain Res2012，1471，： | 1 |
| 8 | Threhalose production at high temperature exploiting an immobilized cell bioreactor显示文摘 | Lernia I D Schiraldi C Generoso M | 2002 | Extremophiles2002，6，： | 1 |
| 9 | Protection against increased intestinal permeability and bacterial translocation induced by intestinal obstruction in mice treated with viable and heat-killed Saccha- romyces boulardii显示文摘 | GENEROSO S V VIANA M L SANTOS R G | 2011 | Eur J Nntr2011，50，4： | 1 |
| 10 | Aerosols effect on the cloud droplet size monitored from satellite显示文摘 | Breon F TanréD Generoso S | | Science0，202，2955： | 1 |
| 11 | The role of L-arginine-nitrie oxide pathway in bacterial transloeation显示文摘 | Viana M L Dos Santos Rd Generoso Sde V | 2013 | Amino Acids2013，45，5： | 1 |
| 12 | Prevalence ofpressure ulcers in hospitals in Brazil and association with nutri-tional status-a multicenter, cross-sectional study 显示文摘 | Brito PA de Vasconcelos Generoso S Correia MI | 2013 | Nutri-tion2013，29，4： | 1 |
| 13 | Subjective global assessment:a reliable nutritional assessment tool to predict outcomes in critically ill patients显示文摘 | Fontes D Generoso Sde V Toulson Davisson Correia MI | 2014 | Clin Nutr2014，33，2： | 1 |
| 14 | Pathophysiology of acute meningitis caused by Streptococcus pneumoniae and adjunctive therapy approaches显示文摘 | Barichello T Generoso JS Collodel A | | 0，，05： | 1 |
| 15 | Gluta- mine supplementation decreases intestinal permeability and preserves gut mucosa integrity in an experimental mouse model显示文摘 | Dos Santos R D Viana M L Generoso S V | 2010 | JPEN J Parenter Enteral Nutr2010，34，4： | 1 |
| 16 | Prevalence of pressure ulcers in hospitals in Brazil and association with nutritional status--a multicenter,cross-section study显示文摘 | Brito P A Generoso Sde V Correia M I | 2013 | Nutrition2013，29，4： | 1 |
| 17 | Targets for adjunctive therapy in pneumococcal,meningitis显示文摘 | Barichello T Collodel A Generoso J S et aI | 2015 | J Neuroimmunol2015，278，： | 1 |
| 18 | Evaluation of the brain-derived neurotrophic factor,nerve growth factor and memory in adult rats survivors of the neonatal menin gitis by Streptococcus agalactiae 显示文摘 | Barichello T Lemos JC Generoso JS | 2013 | Brain Research Bul letin2013，92，： | 1 |
| 19 | The role of l -arginine-nitric oxide pathway in bacterial translocation显示文摘 | Mirelle Lomar Viana Rosana das Gra?as Carvalho Santos Simone de Vasconcelos Generoso Jacques Robert Nicoli Flaviano dos Santos Martins José Augusto Nogueira-Machado Rosa Maria Esteves Arantes Maria Isabel Toulson Davisson Correia Valbert Nascimento Cardos | 2013 | Amino Acids2013，，： | 1 |
| 20 | Are the Clinical and Pathological Features of Differentiated Thyroid Carcinoma Really Changed over the Last 35 Years? Study on 4187 Patients from a Single Italian Institution to Answer this Question显示文摘 | Rossella Elisei Eleonora Molinaro Laura Agate Valeria Bottici Lucio Masserini Claudia Ceccarelli Francesco Lippi Lucia Grasso Fulvio Basolo Generoso Bevilacqua Paolo Miccoli Giancarlo Di Coscio Paolo Vitti Furio Pacini Aldo Pinchera | 2010 | The Journal of Clinical Endocrinology & Metabolism2010，，4： | 1 |
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