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| 1 | Localization of AKAP4 and tubulin proteins in sperm with reduced motility显示文摘瞄准:表现屏蔽,与 A-kinase 抛锚蛋白质有关 4 (AKAP4 ) 并且导管素蛋白质,在有不在或严重地减少的活动性的精子组织以便检测含纤维的鞘和 axonemal 的地位。方法:免疫细胞化学导管素学习,用作积极控制,并且 AKAP4 被执行检测存在和在不同精子样品的这些蛋白质的分发。精子的词法特征被传播电子显微镜(TEM ) 学习,结果用在以前的研究报导的一个公式被详细描述。PCR 在从外部血淋巴细胞提取分析 Akap4 和 Akap3 基因的部分序列的 DNA 上被执行。结果:导管素和 AKAP4 的 Immunolabelling 显示出不同模式,它导致了我们把病人划分成组。在组Ⅰ, AKAP4 和导管素的缺席被揭示,尽管这些病人没在 Akap4/Akap3 有约束力的地点显示出改变。TEM 评估加亮那坏死的高存在与全部的精子无法移动被联系。在组Ⅱ,一个常规 AKAP4 和导管素信号是在场的,尽管活动性被减少, TEM 分析揭示了未成熟的存在。在组Ⅲ,一个弱 AKAP4 标签与正常在联系了,染色的导管素和减少的活动性被观察,含纤维的鞘的严重组织的破坏被 TEM 加亮。结论:当在精子活动性的 AKAP4 的角色是不清楚的时,不在或弱的标记 AKAP4 似乎与不在或弱的精子活动性被联系。 | Elena Moretti Giacomo Scapigliati Nicola Antonio Pascarelli Baccio Baccetti Giulia Collodel | 2007 | Asian Journal of Andrology2007，9，5： | 6 |
| 2 | Can Helicobacter pylori infection influence human reproduction?显示文摘Helicobacter pylori(H.pylori)infection could be associated with extra-digestive diseases.Here,we report the evidences concerning the decrease in reproductive potential occurring in individuals infected by H.pylori,especially by strains expressing CagA.This infection is more prevalent in individuals with fertility disorders.Infected women have anti-H.pylori antibodies in cervical mucus and follicular fluid that may decrease sperm motility and cross react immunologically with spermatozoa,conceivably hampering the oocyte/sperm fusion.Infection by CagA positive organisms enhances the risk of preeclampsia,which is a main cause of foetus death.These findings are supported by the results of experimental infections of pregnant mice,which may cause reabsorption of a high number of foetuses and alter the balance between Th1 and Th2 cell response.Infected men have decreased sperm motility,viability and numbers of normally shaped sperm and augmented systemic levels of inflammatory cytokines,such as TNF-α,which may damage spermatozoa.In countries where parasitic infestation is endemic,detrimental effects of infection upon spermatozoa may not occur,because the immune response to parasites could determine a switch from a predominant Th1 type to Th2 type lymphocytes,with production of anti-inflammatory cytokines.In conclusion,the evidences gathered until now should be taken into consideration for future studies aiming to explore the possible role of H.pylori infection on human reproduction. | Elena Moretti Natale Figura Giulia Collodel Antonio Ponzetto | 2014 | World Journal of Gastroenterology2014，20，19： | 6 |
| 3 | 18,X,Y aneuploidies and transmission electron microscopy studies in spermatozoa from five carriers of different reciprocal translocations显示文摘我们与不同平衡相互的 translocations 从五个不肥沃的人分析了呼喊的精子贡献染色体的 meiotic 分离的学习 18, X 和 Y 并且另外由传播评估精子形态学电子显微镜学(TEM ) 分析。常规淋巴细胞 karyotype 分析加亮不同相互的平衡 translocations:t (12; 13 ) , t (4; 9 ) , t (X; 8 ) , t (8; 10 ) 并且 t (3; 16 ) 。精液分析被光和 TEM 执行。在 situ 杂交的荧光为染色体用 centromeric 探针在精子原子核上直接被执行 18, X 和 Y。在现在的学习考虑的平衡相互的 translocations 的搬运人显示出精子病理的一个很类似的模式:apoptosis 和未成熟的传播存在。所有病人显示出 meiotic 分离精神错乱,由特别地与第一个 meiotic 部门的失败有关的精子 diploidies 和性染色体 disomies 的存在加亮。然而,染色体 18 aneuploidy 的增加的发生从 t 在精子被检测(X; 8 ) 并且 t (8; 10 ) 搬运人。我们也从象 t 那样的性染色体报导了价值(X; 8 ) ,尽管 X 染色体涉及 translocation。因为有相互的 translocations 和 spermatogenetic 缺陷的病人是 intracytoplasmic 精子注射周期的候选人,精子参数,并且特别地 aneuploidy 的水平的学习评价,将在风险为夫妇提供更好的信息并且将在整个 meiotic 过程上为 chromosomal 重新整理的效果的更好的理解在文学贡献数据并且,特别地在没涉及 translocation 的染色体上。 | Elena Moretti Nicola Antonio Pascarelli Valentina Giannerini Michela Geminiani Cecilia Anichini Giulia Collodel | 2009 | Asian Journal of Andrology2009，11，3： | 4 |
| 4 | Effect of trans- resveratrol on induced oxidative stress in human sperm and in rat germinal cells 显示文摘 | Collodel G Federico MG Geminiani M | 2011 | Reprod Toxicol2011，2，31： | 1 |
| 5 | Apoptosis in human ejaculated sperm cells (notulae seminologicae 9)显示文摘 | Baccetti B Collodel G Piomboni P | 1996 | Submicrose Cytol Patbol1996，28，4： | 1 |
| 6 | Localization of human follicle-stimulating hormone in the testis显示文摘 | Baccetti B Collodel G Costantino-Ceccarini E | 1998 | FASEB J1998，12，11： | 1 |
| 7 | Fluorescence in situ hybridization and molecular studies in infertile men with dysplasia of the fibrous sheath显示文摘 | Baccetti B Collodel G Gambera L | | 0，，1： | 1 |
| 8 | Gene deletions in an infertile man with sperm fibrous sheath dysplasia显示文摘 | Baccetti B Collodel G Estenoz M | | 0，，10： | 1 |
| 9 | Generic sperm defects and consanguinity显示文摘 | Baccetti B Capitani S Collodel G | 2001 | Hum Reprod2001，16，7： | 1 |
| 10 | Detection of obestatin in seminal plasma and its relationship with ghrelin and semen parameters显示文摘 | Elena Moretti Giulia Collodel Francesca Iacoponi Michela Geminiani Nicola Antonio Pascarelli Stella Campagna Beatrice Franci Natale Figura | 2011 | Fertility and Sterility2011，，7： | 1 |
| 11 | Effect of a bacterial lipopolysaccharide treatment on rabbit testis and ejaculated sperm显示文摘 | Collodel G Castellini C del Vecchio MT | | 0，，03： | 1 |
| 12 | Localization of human follicle-stimulating hormone in the testis 显示文摘 | BACCETTI B COLLODEL G COSTANTINO-CECCARINI E | 1998 | FASEBJ1998，12，： | 1 |
| 13 | Apoptosis in human ejaculated sperm cells显示文摘 | Baccetti B Collodel G Piomboni P | 1996 | J Submicrosc Cytol Pathol1996，28，4： | 1 |
| 14 | Pathophysiology of acute meningitis caused by Streptococcus pneumoniae and adjunctive therapy approaches显示文摘 | Barichello T Generoso JS Collodel A | | 0，，05： | 1 |
| 15 | Biochemical and morphological study of human articular chondrocytes cultivat- ed in the presence of pulsed signal therapy 显示文摘 | Fioravanti A Nerucci F Collodel G | 2002 | Ann Rheum Dis2002，61，11： | 1 |
| 16 | Targets for adjunctive therapy in pneumococcal,meningitis显示文摘 | Barichello T Collodel A Generoso J S et aI | 2015 | J Neuroimmunol2015，278，： | 1 |
| 17 | TEM,FISH and molecular studies in infertile men with pericentric inversionof chromosome 9显示文摘 | COLLODEL G MORETTI E CAPITANI S | | 0，，： | 1 |
| 18 | Localization ofhuman follicle-stimulating hormone in the testis 显示文摘 | Baccetti B Collodel G Costantino-Ceccarini E | 1998 | FASEB J1998，12，11： | 1 |
| 19 | Effect of trans - res- veratrol on induced oxidative stress in human sperm and in rat ger- minal cells 显示文摘 | Collodel G Federico MG Geminiani M | 2011 | Reprod Toxicol2011，31，23： | 1 |
| 20 | Recent advances in human sperm pathology显示文摘 | Baccetti B Capitani S Collodel G | 2002 | Contraception2002，65，4： | 1 |
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