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| 1 | Infected pancreatic necrosis: Not necessarily a late event in acute pancreatitis显示文摘It is widely believed that infection of pancreatic necrosis is a late event in the natural course of acute pancreatitis. This paper discusses the available data on the timing of pancreatic infection. It appears that infected pancreatic necrosis occurs early in almost a quarter of patients. This has practical implications for the type, timing and duration of preventive strategies used in these patients. There are also implications for the classification of severity in patients with acute pancreatitis. Given that the main determinants of severity are both local and systemic complications and that they can occur both early and late in the course of acute pancreatitis, the classification of severity should be based on their presence or absence rather than on when they occur. To do otherwise, and in particular overlook early infected pancreatic necrosis, may lead to a misclassification error and fallacies of clinical studies in patients with acute pancreatitis. | Maxim S Petrov Vincent Chong John A Windsor | 2011 | World Journal of Gastroenterology2011，17，27： | 10 |
| 2 | Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting. | Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov | 2014 | World Journal of Gastroenterology2014，20，45： | 9 |
| 3 | Determinant-Based Classification of Acute Pancreatitis Severity: An International Multidisciplinary Consultation显示文摘 | E. Patchen Dellinger Christopher E. Forsmark Peter Layer Philippe Lévy Enrique Maraví-Poma Maxim S. Petrov Tooru Shimosegawa Ajith K. Siriwardena Generoso Uomo David C. Whitcomb John A. Windsor | 2012 | Annals of Surgery2012，，6： | 7 |
| 4 | Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 2: Current management显示文摘 | Axel Dignass James O. Lindsay Andreas Sturm Alastair Windsor Jean-Frederic Colombel Mathieu Allez Gert D’Haens André D’Hoore Gerassimos Mantzaris Gottfried Novacek Tom ?resland Walter Reinisch Miquel Sans Eduard Stange Severine Vermeire Simon Travis Gert | 2012 | Journal of Crohn’s and Colitis2012，，10： | 4 |
| 5 | Helicobacter pylori eradication in Western Australia using novel quadruple therapy combinations显示文摘 | C. Y. Tay H. M. Windsor F. Thirriot W. Lu C. Conway T. T. Perkins B. J. Marshall | 2012 | Aliment Pharmacol Ther (pt)2012，，11： | 3 |
| 6 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Current management显示文摘 | A. Dignass G. Van Assche J.O. Lindsay M. Lémann J. S?derholm J.F. Colombel S. Danese A. D’Hoore M. Gassull F. Gomollón D.W. Hommes P. Michetti C. O’Morain T. ?resland A. Windsor E.F. Stange S.P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 7 | Organ Failure and Infection of Pancreatic Necrosis as Determinants of Mortality in Patients With Acute Pancreatitis显示文摘 | Maxim S. Petrov Satyanarayan Shanbhag Mandira Chakraborty Anthony R.J. Phillips John A. Windsor | 2010 | Gastroenterology2010，，3： | 2 |
| 8 | Numerically quantifying the relative importance of topography and buoyancy in driving groundwater flow显示文摘Both topography and buoyancy can drive groundwater flow;however,the interactions between them are still poorly understood.In this paper,the authors conduct numerical simulations of variable-density fluid flow and heat transport to quantify their relative importance.The finite element modeling experiments on a 2-D conceptual model reveal that the pattern of groundwater flow depends largely upon the relative magnitude of the flow rate due to topography alone and the flow rate due to buoyancy alone.When fluid velocity due to topography is greater than that due to buoyancy at large water table gradients,topography-driven 'forced convection' overwhelms buoyancy-driven 'free convection'.When flow velocity due to buoyancy is greater than that due to topography at small water table gradients,mixed free and forced convection takes place.In this case,free convection becomes dominant,but topography-driven flow still plays an important role since it pushes the free convection cells to migrate laterally in the downhill direction.Consequently,hydrothermal fluid flow remains changing periodically with time and no steady state can be reached.The presence of a low-permeability layer near the surface helps eliminate the topography effect on the underlying free convection. | YANG JianWen 1,2,FENG ZuoHai 1,LUO XianRong 1 & CHEN YuanRong 1 1 Faculty of Earth Sciences,Guilin University of Technology,Guilin 541004,China 2 Department of Earth and Environmental Sciences,University of Windsor,Windsor,Ontario,N9B 3P4,Canada | 2010 | Science China Earth Sciences2010，53，1： | 2 |
| 9 | Ac Stark effect in a doubly driven three- level atom 显示文摘 | CHANGJIANG WEI SUTER D WINDSOR A S | 1998 | 58:2310-23181998，58，： | 2 |
| 10 | Fluid Therapy in Acute Pancreatitis: Anybody?s Guess显示文摘 | Matthew D. Haydock Anubhav Mittal Heath R. Wilms Anthony Phillips Maxim S. Petrov John A. Windsor | 2013 | Annals of Surgery2013，，2： | 2 |
| 11 | Esmolol potentiates reduction of minimum alveolar isoflurane concentration by alfentanil显示文摘 | JOHANSEN JW SCHNEIDER G WINDSOR AM | 1998 | Anesth Analg1998，87，1： | 1 |
| 12 | Neutron Diffraction Methods for the Study of Residual Stress Fields显示文摘 | ALLEN A J HUTCHINGS M T WINDSOR C G | 1985 | Adv Phys1985，34，4： | 1 |
| 13 | Diagnosis and management of isolated pancreatic tuberculosis:recent experience and literature review显示文摘 | Woodfield JC Windsor JA Godfrey CC | 2004 | ANZ J Surg2004，74，： | 1 |
| 14 | Tile effects of tumor necrosis factor-al- pha,interleukin-lbeta,interleukin-6,and transforming growth factor- betal on pulp fibroblast mediated collagen degradation 显示文摘 | Wisithphrom K Windsor LJ | 2006 | J Endod2006，32，9： | 1 |
| 15 | Foot- and- mouth disease control and eradication in the bicol surveillance buffer zone of the Philippines 显示文摘 | WINDSOR P A FREEMAN P G ABILAR | 2011 | Transbound Emerg Dis2011，58，5： | 1 |
| 16 | Sclerosing peritonitis due to practolol:a report on 9 cases and their surgical management显示文摘 | Eltringham WK Espiner HJ Windsor CW | 1977 | Br J Surg1977，64，4： | 1 |
| 17 | Immediate IL-10 expression following major orthopaedic trauma: relationship to anti-inflammatory response and subsequent development of sepsis显示文摘 | P. V. Giannoudis R. M. Smith S. L. Perry A. J. Windsor R. A. Dickson M. C. Bellamy | 2000 | Intensive Care Medicine2000，，8： | 1 |
| 18 | Compared with parenteral nutrition,enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis 显示文摘 | Windsor AC Kanwar S Li AG | 1998 | 42(3):431-4351998，42，3： | 1 |
| 19 | Experimental therapies in Ewing's sarcoma 显示文摘 | Windsor R Strauss S Seddon R | 2009 | Expert Opin Investig Drugs2009，18，2： | 1 |
| 20 | Inhibiting cholesterol absorption with CP-88, 818 (beta-tigogenin cellobioside; tiqueside): studies in normal and hyperlipidemic subjects 显示文摘 | Harris W S Dujovne C A Windsor S L | 1997 | J Cardiovasc Phar- macol1997，30，1： | 1 |
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