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| 1 | Effect of vildagliptin as add-on therapy to a low-dose metformin显示文摘AIM:To evaluate the efficacy and safety of the addition of vildagliptin to low-dose metformin and compare it to an uptitration of metformin in type 2 diabetes mellitus(T2DM) patients who have inadequate control with metformin monotherapy.METHODS:Eligible patients were randomized to receive vildagliptin 100 mg qd or metformin(500 mg qd for 2 wk and then 500 mg bid) added to open label me tformin 500 mg bid for the 24 wk.The primary endpoi nt was baseline to endpoint hemoglobin A1c(HbA1c) change.RESULTS:The adjusted mean change from baseline in HbA1c at the 24th wk was-0.51% in the vildagliptin/metformin group(mean baseline HbA1c:7.4%) and-0.37% in the metformin monothera py group(mean baseline HbA1c:7.3%).The mean diffe rence was-0.14% with 95% Confidence Interval(-0.24%,-0.05%).As non-inf e riority(margin of 0.4%) was achieved,a test for superiority was performed.This test showed statistically significant superiority of the combination over monotherapy group(P = 0.002).Gastrointestinal(GI) adverse events were signif icantly more frequent in the metformin group than the combin ation group(21.0% vs 15.4%,P = 0.032).CONCLUSION:In patients with T2DM inadequately controlled with metformin up to 1000 mg daily,the addition of vildagliptin 100 mg daily achieved larger HbA1c reduction with fewer GI events than with increa sing the metformin dose. | Claudia Filozof Sherwyn Schwartz James E Foley | 2010 | World Journal of Diabetes2010，1，1： | 8 |
| 2 | Analysis of electric vehicle charging using the traditional generation expansion planning analysis tool WASP-IV显示文摘Electric vehicles(EV)are proposed as a measure to reduce greenhouse gas emissions in transport and support increased wind power penetration across modern power systems.Optimal benefits can only be achieved,if EVs are deployed effectively,so that the exhaust emissions are not substituted by additional emissions in the electricity sector,which can be implemented using Smart Grid controls.This research presents the results of an EV roll-out in the all island grid(AIG)in Ireland using the long term generation expansion planning model called the Wien Automatic System Planning IV(WASP-IV)tool to measure carbon dioxide emissions and changes in total energy.The model incorporates all generators and operational requirements while meeting environmental emissions,fuel availability and generator operational and maintenance constraints to optimize economic dispatch and unit commitment power dispatch.In the study three distinct scenarios are investigated base case,peak and off-peak charging to simulate the impacts of EV’s in the AIG up to 2025. | Aoife FOLEY Brian O GALLACHOIR | 2015 | Journal of Modern Power Systems and Clean Energy2015，3，2： | 8 |
| 3 | A self-learning TLBO based dynamic economic/environmental dispatch considering multiple plug-in electric vehicle loads显示文摘Economic and environmental load dispatch aims to determine the amount of electricity generated from power plants to meet load demand while minimizing fossil fuel costs and air pollution emissions subject to operational and licensing requirements.These two scheduling problems are commonly formulated with non-smooth cost functions respectively considering various effects and constraints,such as the valve point effect,power balance and ramprate limits.The expected increase in plug-in electric vehicles is likely to see a significant impact on the power system due to high charging power consumption and significant uncertainty in charging times.In this paper,multiple electric vehicle charging profiles are comparatively integrated into a 24-hour load demand in an economic and environment dispatch model.Self-learning teaching-learning based optimization(TLBO)is employed to solve the non-convex non-linear dispatch problems.Numerical results onwell-known benchmark functions,as well as test systems with different scales of generation units show the significance of the new scheduling method. | Zhile YANG Kang LI Qun NIU Yusheng XUE Aoife FOLEY | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，4： | 8 |
| 4 | Assessment of stable coronary artery disease by cardiovascular magnetic resonance imaging: Current and emerging techniques显示文摘Coronary artery disease(CAD) is a leading cause of death and disability worldwide. Cardiovascular magnetic resonance(CMR) is established in clinical practice guidelines with a growing evidence base supporting its use to aid the diagnosis and management of patients with suspected or established CAD. CMR is a multi-parametric imaging modality that yields high spatial resolution images that can be acquired in any plane for the assessment of global and regional cardiac function, myocardial perfusion and viability, tissue characterisation and coronary artery anatomy, all within a single study protocol and without exposure to ionising radiation. Advances in technology and acquisition techniques continue to progress the utility of CMR across a wide spectrum of cardiovascular disease, and the publication of large scale clinical trials continues to strengthen the role of CMR in daily cardiology practice. This article aims to review current practice and explore the future directions of multi-parametric CMR imaging in the investigation of stable CAD. | James RJ Foley Sven Plein John P Greenwood | 2017 | World Journal of Cardiology2017，9，2： | 6 |
| 5 | Vildagliptin-insulin combination improves glycemic control in Asians with type 2 diabetes显示文摘AIM: To assess the efficacy and safety of vildagliptin 50 mg bid as add-on therapy to insulin in Asian patients with type 2 diabetes mellitus(T2DM).METHODS: This was a post hoc analysis of a subgroup of Asian patients from a multicenter,randomized,double-blind,placebo-controlled,parallel-group study in T2DM patients inadequately controlled by stable insulin therapy,with or without metformin.A total of 173 patients were randomized 1:1 to receive treatment with vildagliptin 50 mg bid(n = 87) or placebo(n = 86) for 24 wk.Changes in HbA1c and fasting plasma glucose(FPG),from baseline to study endpoint,were analyzed using an analysis of covariance model.Change from baseline to endpoint in body weight was summarized by treatment.Safety and tolerability of vildagliptin was also evaluated.RESULTS: After 24 wk,the difference in adjusted mean change in HbA1c between vildagliptin and placebo was 0.82%(8.96 mmol/mol;P < 0.001) in Asian subgroup,0.85%(9.29 mmol/mol;P < 0.001) in patients also receiving metformin,and 0.73%(7.98 mmol/mol;P < 0.001) in patients without metformin,all in favor of vildagliptin.There was no significant difference in the change in FPG between treatments.Weight was stable in both treatment groups(+0.3 kg and-0.2 kg,for vildagliptin and placebo,respectively).Overall,vildagliptin was safe and well tolerated with similarly low incidences of hypoglycemia(8.0% vs 8.1%) and no severe hypoglycemic events were experienced in either group.CONCLUSION: In Asian patients inadequately controlled with insulin(with or without concomitant metformin),insulin-vildagliptin combination treatment significantly reduced HbA1c compared with placebo,without an increase in risk of hypoglycemia or weight gain. | Plamen Kozlovski James Foley Qing Shao Valentina Lukashevich Wolfgang Kothny | 2013 | World Journal of Diabetes2013，4，4： | 6 |
| 6 | Dysphagia After Stroke: Incidence, Diagnosis, and Pulmonary Complications显示文摘 | Rosemary Martino Norine Foley Sanjit Bhogal Nicholas Diamant Mark Speechley Robert Teasell | 2005 | Stroke2005，，12： | 5 |
| 7 | 国外乡村环境管护制度显示文摘加强农业农村生态管护是当前农业农村生态环境综合整治和乡村管理发展的必然趋势,也是解决农业农村生态景观问题的关键管理策略。本文节选了一些国外的乡村环境管护制度,通过对国外相关政策的了解研究,有助于认识我国农业农村生态管护的现状和规范未来的发展方向。 | Foley J.A. 梁苗 | 2016 | 农村工作通讯2016，，2： | 4 |
| 8 | 护士的贡献和她们的安全性显示文摘从南非墙上标有“禁止带枪”标记的诊所到密克罗尼西亚没有自来水的乡村医院;从洛杉矶服务于全球非英语交流的城市医院到荒芜的阿拉斯加州有护理的诊所,护士都将提供她们最好的护理,这一点是值得称赞的。不过护士同样也应该照顾好自己,以使他们可以继续为患者提供护理,同时维持吸收和保留新护士的职业能力。1982-1990年的基础护理书上卫生保健人员的风险仅仅在第一章提出。这篇文章为护士安全作了一般介绍。首先健康和安全是主要部分,概括了风险减少的控制结构层次,其次美国护理学会将安全要点具体化并且护士安全职业需求将被提出,通过讨论这些患者和护士的安全性之间的连接,有关护士安全性将被引起注意。 | Mary Foley 陈景景(编译) | 2006 | 护理实践与研究2006，3，2： | 4 |
| 9 | Weight neutrality with the DPP-4 inhibitor, vildagliptin: Mechanistic basis and clinical experience显示文摘 | James Foley | 2010 | Vascular Health and Risk Management (default)2010，，： | 3 |
| 10 | Vildagliptin Enhances Islet Responsiveness to Both Hyper- and Hypoglycemia in Patients with Type 2 Diabetes显示文摘 | Bo Ahrén Anja Schweizer Sylvie Dejager Beth E. Dunning Peter M. Nilsson Margaretha Persson James E. Foley | 2009 | The Journal of Clinical Endocrinology & Metabolism2009，，4： | 3 |
| 11 | 口头诗人说了什么(用他们自己的“词”)显示文摘《怎样阅读一首口头诗歌》一书的核心要义,是向读者受众揭示诗歌创作和“阅读”的不同方式。我们将通过以下三方面的努力以成为更好的受众(alldience):1.尽可能地开阔视野;2.认识到口头艺术种类的多元性;3.重新思考关于诗性交流最为基本的假设。 | 约翰·迈尔斯·弗里(John Miles Foley) 朱刚 | 2009 | 民俗研究2009，，1： | 3 |
| 12 | Four multidetector-row helical CT: image quality and volume coverage speed显示文摘 | Hu H He H D Foley W D | 2000 | Radiology2000，215，1： | 2 |
| 13 | The Role of Endoscopy in the Assessment and Treatment of Esophageal Cancer显示文摘 | J.A. Evans D.S. Early V. Chandraskhara K.V. Chathadi R. Fanelli D.A. Fisher K. Foley J.H. Hwang T.L. Jue S. Pasha R. Sharaf A. Shergill J.A. Dominitz B.D. Cash | 2012 | Gastrointestinal Endoscopy2012，，： | 2 |
| 14 | Current knowledge and future directions of TLR and NOD signaling in sepsis显示文摘The incidence of sepsis is increasing over time, along with an increased risk of dying from the condition. Sepsis care costs billions annually in the United States. Death from sepsis is understood to be a complex process, driven by a lack of normal immune homeostatic functions and excessive production of proinflammatory cytokines, which leads to multi-organ failure. The Toll-like receptor(TLR) family, one of whose members was initially discovered in Drosophila, performs an important role in the recognition of microbial pathogens. These pattern recognition receptors(PRRs), upon sensing invading microorganisms, activate intracellular signal transduction pathways. NOD signaling is also involved in the recognition of bacteria and acts synergistically with the TLR family in initiating an efficient immune response for the eradication of invading microbial pathogens. TLRs and NOD1/NOD2 respond to different pathogenassociated molecular patterns(PAMPs). Modulation of both TLR and NOD signaling is an area of research that has prompted much excitement and debate as a therapeutic strategy in the management of sepsis. Molecules targeting TLR and NOD signaling pathways exist but regrettably thus far none have proven efficacy from clinical trials. | Niamh M Foley Jian Wang H Paul Redmond Jiang-Huai Wang | 2014 | Journal of Medical Colleges of PLA(China)2014，29，4： | 2 |
| 15 | Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus显示文摘 | Lasse R. Braathen Rolf-Markus Szeimies Nicole Basset-Seguin Robert Bissonnette Peter Foley David Pariser Rik Roelandts Ann-Marie Wennberg Colin A. Morton | 2007 | Journal of the American Academy of Dermatology2007，，： | 2 |
| 16 | An integrated biosphere model of land surface processes,terrestrial carbon balance ,and vegetation dynamics显示文摘 | Foley J A Prentice C Ramankutty N | 1996 | Global Biogeochemical cycles1996，10，4： | 2 |
| 17 | Fibrinogen as a Hemostatic Agent显示文摘 | Benny S?rensen Ole Larsen Catherine Rea Mariann Tang Jonathan Foley Christian Fenger-Eriksen | 2012 | Semin Thromb Hemost2012，，03： | 2 |
| 18 | Minimally Invasive Lumbar Fusion显示文摘 | Kevin T. Foley Langston T. Holly James D. Schwender | 2003 | Spine (S Suppl)2003，，15： | 2 |
| 19 | Impaired Uptake of Serotonin by Platelets From Patients With Irritable Bowel Syndrome Correlates With Duodenal Immune Activation显示文摘 | Stephen Foley Klara Garsed Gulzar Singh Nathalie P. Duroudier Caroline Swan Ian P. Hall Abed Zaitoun Andrew Bennett Charles Marsden Geoffrey Holmes Andrew Walls Robin C. Spiller | 2011 | Gastroenterology2011，，5： | 2 |
| 20 | Guidelines for endoscopy in pregnant and lactating women显示文摘 | Amandeep K. Shergill Tamir Ben-Menachem Vinay Chandrasekhara Krishnavel Chathadi G. Anton Decker John A. Evans Dana S. Early Robert D. Fanelli Deborah A. Fisher Kimberly Q. Foley Norio Fukami Joo Ha Hwang Rajeev Jain Terry L. Jue Khalid M. Khan Jennifer L | 2012 | Gastrointestinal Endoscopy2012，，1： | 2 |
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