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| 1 | Liver pathology of hepatitis C,beyond grading and stagingof the disease显示文摘Liver biopsy evaluation plays a critical role in management of patients with viral hepatitis C. In patients with acute viral hepatitis, a liver biopsy, though uncommonly performed, helps to rule out other nonviral causes of deranged liver function. In chronic viral hepatitis C, it is considered the gold standard in assessment of the degree of necroinflammation and the stage of fibrosis, to help guide treatment and determine prognosis. It also helps rule out any concomitant diseases such as steatohepatitis, hemochromatosis or others. In patients with chronic progressive liver disease with cirrhosis and dominant nodules, a targeted liver biopsy is helpful in differentiating a regenerative nodule from dysplastic nodule or hepatocellular carcinoma. In the setting of transplantation, the liver biopsy helps distinguish recurrent hepatitis C from acute rejection and also is invaluable in the diagnosis of fibrosing cholestatic hepatitis, a rare variant of recurrent hepatitis C. This comprehensive review discusses the entire spectrum of pathologic findings in the course of hepatitis C infection. | Sadhna Dhingra Stephen C Ward Swan N Thung | 2016 | World Journal of Gastroenterology2016，22，4： | 6 |
| 2 | Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography显示文摘AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures. | Michael P Swan Michael J Bourke Stephen J Williams Sina Alexander Alan Moss Rick Hope David Ruppin | 2011 | World Journal of Gastroenterology2011，17，45： | 6 |
| 3 | Authors and Open Access:Effective Ways to Achieve OA in China显示文摘Although there are effective methods available to authors for providing open access to their work, more than half are still not doing so and provision in China is poorer than in many other countries. There are a number of issues and concerns that dissuade authors from making their work open access: some are still unaware of the concept and of the increased visibility and impact that open access brings; many are unfamiliar with open access journals and how they work; many are uninformed about self-archiving and for some of those who are aware of the possibility of providing open access by this means, concerns about copyright and technical issues remain.Yet all these worries can be addressed with simple facts that reassure and encourage authors to adopt open access to benefit themselves,their research and their teaching. There is also a wealth of resources now available to authors that provide information and advice on open access and its effects. As institutions and research funders, both with a strong interest in maximising the visibility and impact of research they support, begin to develop formal policies on open access, models for its provision are emerging. The optimal model is a frills' variant) or by service providers who add functionality or selectivity to provide users with value-enhanced products. | Alma Swan | 2005 | 图书情报工作2005，49，12： | 5 |
| 4 | 肝的周期性的巨大的 hemangiomas : 有文学评论的二个稀罕案例的报告显示文摘 Most hepatic hemangiomas(HHs) are small,asymptomatic and do not require clinical intervention.Surgical resection is only indicated for symptomatic hemangiomas.We report here cases of recurrent HHs in 2 women of 37 and 40 years old,who initially presented with abdominal pain and mass.Radiological examination of each tumor revealed a solitary tumor of 14 and 20 cm in diameter,respectively.Surgical liver segmental resections were performed in both,and the diagnosis of cavernous hemangioma was confirmed.Both patients had recurrent tumor on subsequent radiological examination 4-5 years after the initial surgery.In the first patient,a 15 cm recurrent hemangioma was resected,but multiple hemangiomas were again detected 8 years later occupying the other hepatic lobe,which was not amendable for resection.In the second patient,a 16 cm hemangioma was seen on radiogram,and because the lesion was not symptomatic,conservative observation was offered.Recurrence after liver resection of giant hemangioma is extremely rare.The pathogenesis of tumor progression and recurrence is unknown,as is the management of these patients with recurrent hemangioma,particularly when it is extensive and unresectable. | Hongfa Zhu Khaled Obeidat Jie Ouyang Sasan Roayaie Myron E Schwartz Swan N Thung | 2012 | World Journal of Gastrointestinal Surgery2012，4，11： | 5 |
| 5 | Preoperative immunonutrition in patients undergoing liver resection:A prospective randomized trial显示文摘BACKGROUND Preoperative supplementation with immunonutrients, including arginine and n-3 fatty acids, has been shown in a number of systematic reviews to reduce infectious complications in patients who have undergone gastrointestinal surgery. Limited information, however, is available on the benefits of nutritional supplementation enriched with arginine and n-3 fatty acids in patients undergoing liver resection.AIM To evaluate the effects of preoperative nutritional supplementation enriched with arginine and n-3 fatty acids on inflammatory and immunologic markers and clinical outcome in patients undergoing liver resection.METHODS Thirty-four patients undergoing liver resection were randomized to either five days of preoperative Impact? [1020 kcal/d, immunonutrition(IMN) group], or standard care [no supplementation, standard care(STD) group]. Nutritional status was measured at study entry by subjective global assessment(SGA).Functional assessments(grip strength, fatigue and performance status) were carried out at study entry, on the day prior to surgery, and on postoperative day(POD) 7 and 30. Inflammatory and immune markers were measured at study entry, on the day prior to surgery, and POD 1, 3, 5, 7, 10 and 30. Postoperative complications were recorded prospectively until POD30.RESULTS A total of 32 patients(17 IMN and 15 STD) were analysed. All except four patients were SGA class A. The plasma ratio of(eicosapentaenoic acid plus docosahexaenoic acid) to arachidonic acid was higher in IMN patients on the day prior to surgery and POD 1, 3, 5 and 7(P < 0.05). Plasma interleukin(IL)-6 concentrations were elevated in the IMN group(P = 0.017 for POD7). No treatment effect was detected for functional measures, immune response(white cell count and total lymphocytes) or markers of inflammation(C-reactive protein,tumour necrosis factor-α, IL-8, IL-10). There were 10 patients with infectious complications in the IMN group and 4 in the STD group(P = 0.087). Median hospital stay was 9(range 4–49) d in the IMN group and 8(3-34) d in the STD group(P = 0.476).CONCLUSION In well-nourished patients undergoing elective liver resection, this study failed to show any benefit of preoperative immunonutrition. | Kylie Russell Han-Guang Zhang Lyn K GillANDers Adam SJR Bartlett Helena L Fisk Philip C Calder Peter J Swan Lindsay D Plank | 2019 | World Journal of Hepatology2019，11，3： | 3 |
| 6 | 开放获取机构知识库:强制性存储政策显示文摘全世界所有学科中共有约24000种同行评议期刊,这些期刊每年出版研究论文的约有2亿5千万篇。尽管宣传开放获取的益处使得人们对开放获取的了解有所增加,出版界也逐渐开始进行开放获取实验,但目前只有15%的论文通过作者自愿进行自存储而实现了开放获取(Open Access,即自由地联机获取)。 | Les Carr(著) Alma Swan(著) 李麟(编译) | 2006 | 图书情报工作动态2006，，9： | 3 |
| 7 | Morphologic Features of Extrahepatic Manifestations of Hepatitis C Virus Infection显示文摘 | Huaibin M. Ko Juan C. Hernandez-Prera Hongfa Zhu Steven H. Dikman Harleen K. Sidhu Stephen C. Ward Swan N. Thung Domenico Sansonno | 2012 | Clinical and Developmental Immunology2012，，： | 3 |
| 8 | Combining Clinical, Pathology, and Gene Expression Data to Predict Recurrence of Hepatocellular Carcinoma显示文摘 | Augusto Villanueva Yujin Hoshida Carlo Battiston Victoria Tovar Daniela Sia Clara Alsinet Helena Cornella Arthur Liberzon Masahiro Kobayashi Hiromitsu Kumada Swan N. Thung Jordi Bruix Philippa Newell Craig April Jian–Bing Fan Sasan Roayaie Vincenzo Mazzaf | 2011 | Gastroenterology2011，，5： | 3 |
| 9 | Case Report of Successful Treatment of Fibrosing Cholestatic Hepatitis C with Sofosbuvir and Ribavirin after Liver Transplantation显示文摘 | Brian Kim Anshu Trivedi Swan Thung Priya Grewal | 2014 | Semin Liver Dis2014，，01： | 2 |
| 10 | Clinical course and management of SARS in health care workers in Toronto:a case series显示文摘 | Avendano M Derkach P Swan S | 2003 | CMAJ2003，168，： | 2 |
| 11 | 开放获取发展史大事记显示文摘2007年是开放获取在政策制订和实践推动方面发展迅速的一年。在2007年即将结束的时候,开放获取事业又向前迈出了一步,美国国会将NIH的强制性开放获取政策纳入08年财政拨款法案,意味着如果美国总统批准,该政策将成为法律。此外,越来越多的国家、政府部门、研究机构和资助机构制订并开始实施强制性的开放获取政策,这与最初鼓励性的软性建议相比,无疑具有更积极的意义。
本期我们组织了开放获取专题,集中报道近一段时间来,国际开放获取事业的发展。Alma Swan推出了她一年一度的开放获取主题的台历,今年的主题是开放获取发展史回顾;eIFL今年的开放获取会议在香港举办,视角聚焦在开放获取知识库的建设;从研究人员到信息服务机构都在倡议、呼吁强制性的开放获取政策,甚至针对出版商的抵制活动直接行动起来以行动和对策相回应;在制订开放获取政策的同时,政策制订者们开始考虑与政策相配套的机制的建立,如专职的开放获取办公室、开放获取专员等等。 | Alma Swan(汇编) 刘兰(编译) 黄国彬(编译) 孙巍(编译) 李麟(校) | 2007 | 图书情报工作动态2007，，10： | 2 |
| 12 | Factors that predict bleeding following endoscopic mucosal resection of large colonic lesions显示文摘 | A. Metz M. Bourke A. Moss S. Williams M. Swan K. Byth | 2011 | Endoscopy2011，，06： | 2 |
| 13 | Legislation by Hypothesis: The Case of Task-Based Instruction显示文摘 | Michael Swan | 2005 | Applied Linguistics2005，，： | 2 |
| 14 | Wnt-Pathway Activation in Two Molecular Classes of Hepatocellular Carcinoma and Experimental Modulation by Sorafenib显示文摘 | Anja Lachenmayer Clara Alsinet Radoslav Savic Laia Cabellos Sara Toffanin Yujin Hoshida Augusto Villanueva Beatriz Minguez Philippa Newell Hung-Wen Tsai Jordi Barretina Swan Thung Stephen C. Ward Jordi Bruix Vincenzo Mazzaferro Myron Schwartz Scott L. Fri | 2012 | Clinical Cancer Research2012，，18： | 2 |
| 15 | Impaired Uptake of Serotonin by Platelets From Patients With Irritable Bowel Syndrome Correlates With Duodenal Immune Activation显示文摘 | Stephen Foley Klara Garsed Gulzar Singh Nathalie P. Duroudier Caroline Swan Ian P. Hall Abed Zaitoun Andrew Bennett Charles Marsden Geoffrey Holmes Andrew Walls Robin C. Spiller | 2011 | Gastroenterology2011，，5： | 2 |
| 16 | Parental cigarette smoking and the risk of spontaneous abortion显示文摘 | Windham GC Swan SH Fenster L | 1992 | Am J Epidemiol1992，135，： | 2 |
| 17 | Economic growth and capital accumulation 显示文摘 | Swan T W | 1956 | Economic Record1956，，32： | 1 |
| 18 | Serum uric acid as an index of impaired oxdative metabolism in chronic heart failure显示文摘 | Leyva F Anlcer S Swan Jw | 1997 | Eur Heart J1997，18，： | 1 |
| 19 | Inflammatory cytokine (interleukins 1, 6 and 8 and tumor necrosis factor-ct release from cultured human fetal membranes in response to endotoxic lipopolysacchraride mirrors amniotic fluid concentrations显示文摘 | Fortunato SJ Menon RP Swan KF | 1996 | Am J Obstet Gynecol1996，174，6： | 1 |
| 20 | External fixation techniques for distal radius fractures显示文摘 | CAPO J T SWAN K G Jr TAN V | 2006 | Clin Orthop Relat Res2006，445，5： | 1 |
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