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| 1 | 酶联免疫吸附法测定水中异丙隆显示文摘建立了测定水中异丙隆的酶联免疫吸附法 .灵敏度 0 97μg L ,最低检出限 0 0 3μg L .16种取代脲类除草剂的交叉反应率低于 2 2 % .水样可不经分离提取直接测定 .10 %甲醇、2 %乙腈和 2 %乙醇不影响测定 .比较了 11种与异丙隆结构相近的半抗原的活性 . | 李方实 P.Kremer A.Kettrup | 2003 | 环境科学学报2003，23，3： | 9 |
| 2 | Noninvasive biomarkers in non-alcoholic fatty liver disease:Current status and a glimpse of the future显示文摘The development of non invasive biomarkers of disease has become a major focus of interest in nonalcoholic fatty liver disease(NAFLD). The large prevalence of the disease and the invasive nature of the investigation means that screening with liver biopsy is impractical.In addition to screening, the differentiation of those with simple steatosis vs steatohepatitis and fibrosis is clinically important as the prognosis of each differs.Serum biomarkers may be a combination of simple markers derived from large data sets or direct markers of disease activity. Serum markers of inflammation,apoptosis and oxidative stress in addition to fibrosis have been extensively studied in patients with NAFLD.Other techniques such as transient elastography,magnetic resonance elastography and acoustic radiation force imaging are becoming more established as noninvasive methods of detecting fibrosis in a variety of chronic liver conditions in addition to NAFLD. Newer high throughput methods such as proteomics and glycomics allow the nonhypothesis-driven identification of novel markers and may also potentially contribute to our understanding of the pathogenesis of the condition.This review addresses some of the methodological issues which need to be considered in the search for the ideal biomarker. It is likely that a combination of serum biomarkers and techniques such as transient elastography may provide the optimal diagnostic discrimination however this remains to be proven in large studies. | Emer Fitzpatrick Anil Dhawan | 2014 | World Journal of Gastroenterology2014，20，31： | 6 |
| 3 | Comparison of levofloxacin-containing sequential and standard triple therapies for the eradication of Helicobacter pylori显示文摘 | Zulfikar Polat Abdurrahman Kadayifci Murat Kantarcioglu Ayhan Ozcan Ozdes Emer Ahmet Uygun | 2011 | European Journal of Internal Medicine2011，，2： | 5 |
| 4 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 5 | A role for peroxisome proliferator‐activated receptor gamma in resveratrol‐induced colon cancer cell apoptosis显示文摘 | Virginie Aires Bertrand Brassart Annie Carlier Alessandra Scagliarini Stéphane Mandard Emeric Limagne Eric Solary Laurent Martiny Michel Tarpin Dominique Delmas | 2014 | Mol. Nutr. Food Res2014，，9： | 2 |
| 6 | Transient Elastography Is a Useful Noninvasive Tool for the Evaluation of Fibrosis in Paediatric Chronic Liver Disease显示文摘 | Emer Fitzpatrick Alberto Quaglia Sunitha Vimalesvaran Maria Sole Basso Anil Dhawan | 2013 | Journal of Pediatric Gastroenterology and Nutrition2013，，1： | 2 |
| 7 | Efficacy of a Modified Sequential Therapy Including Bismuth Subcitrate as First‐Line Therapy to Eradicate H elicobacter pylori in a Turkish Population显示文摘 | Ahmet Uygun A. Melih OZEL Bulent Sivri Zulfikar Polat Halil Gen? Yusuf Serdar Sakin Gürkan ?elebi Oya Uygur‐Bayrami?li Cemal Nuri Er?in Abdurrahman Kadayif?i Ozdes Emer Armagan Gunal Sait Bagci | 2012 | Helicobacter2012，，6： | 2 |
| 8 | A role of the ubiquitin-proteasome system in neuropathic pain显示文摘 | ANDREW M GORDON B M EMER M | 2002 | J Neurosci2002，22，4： | 1 |
| 9 | Use of a blunt-tipped microcannula for soft tissuefiller injection in the treatment of linear scleroderma (encoup desabre)显示文摘 | Sivek R Emer J | 2014 | Dermatol Surg2014，40，12： | 1 |
| 10 | Female pattern alopecia:current perspectives显示文摘 | Levy LL Emer JJ | 2013 | Int J Womens Health2013，29，5： | 1 |
| 11 | In need of high-throughput behavioral systems显示文摘 | Dani Brunner Eric Nestler Emer Leahy | 2002 | Drug Discovery Today2002，，18： | 1 |
| 12 | Doppler broadening of neutron elastic scattering kernel in TRIPOLI-显示文摘 | ANDREA Z EMERIC B CEDRIC J | 2013 | Annals of Nuclear En- ergy2013，54，： | 1 |
| 13 | Female pattern alopecia: current perspectives显示文摘 | Levy LL Emer JJ | 2013 | Int J Womens Health2013，，5： | 1 |
| 14 | Alpha-1 antitrypsin deficiency显示文摘 | Emer Kelly Catherine M. Greene Tomas P. Carroll Noel G. McElvaney Shane J. O’Neill | 2010 | Respiratory Medicine2010，，6： | 1 |
| 15 | Inguinal cord lipomas显示文摘 | Carilli S Alper A Emer A | 2004 | Hemia2004，8，3： | 1 |
| 16 | Tarantula:A Vector Extension to the Alpha Architecture显示文摘 | Espasa R Ardanaz F Emer J | 2002 | SIGARCH Comput Archit News2002，30，2： | 1 |
| 17 | Delphos phorylation and intracellular redistribution of VENTRICU1AR connexin43 dur- ing electrical uncoupling induced by ischemia 显示文摘 | Beards LEE MA L emer DL Tadros PN | 2000 | Circ Res2000，87，： | 1 |
| 18 | Investigation of metallic and carbon fibre PEEK fracture fixation devices for three-part proximal humeral fractures显示文摘 | Emer M. Feerick Jim Kennedy Hannan Mullett David FitzPatrick Patrick McGarry | 2013 | Medical Engineering and Physics2013，，6： | 1 |
| 19 | Female pattern alopecia?:current perspectives 显示文摘 | Levy LL Emer JJ | 2013 | Int J Womens Health2013，29，5： | 1 |
| 20 | Neuropathic Sensitization of Behavioral Reflexes and Spinal NMDA Receptor/CaM Kinase II Interactions Are Disrupted in PSD-95 Mutant Mice显示文摘 | Emer M. Garry Andrew Moss Ada Delaney Francis O’Neill James Blakemore Julian Bowen Holger Husi Rory Mitchell Seth G.N. Grant Susan M. Fleetwood-Walker | 2003 | Current Biology2003，，： | 1 |
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